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1. 发明申请

WO2007136176A1 POLYURETHANE FOAM DRESSING COMPRISING DRUG-CONTAINING LAYER AND METHOD FOR MANUFACTURING THE SAME 审中-公开
标题翻译：包含含药层的聚氨酯泡沫包衣及其制造方法
公开(公告)号：WO2007136176A1
公开(公告)日：2007-11-29
申请号：PCT/KR2007/002078
申请日：2007-04-27
申请人： WONBIOGEN CO., LTD. , KIM, Won Il , KANG, Jeong Yeol
发明人： KIM, Won Il , KANG, Jeong Yeol
IPC分类号： A61L15/10
CPC分类号： B32B5/18 , A61L15/26 , A61L15/425 , A61L15/44 , A61L2300/23 , A61L2300/30 , A61L2300/404 , A61L2300/606 , B32B5/20 , B32B27/065 , B32B27/40 , B32B2266/0278 , B32B2535/00 , C08L75/04
摘要： Disclosed herein are a polyurethane foam dressing comprising a drug-containing layer and a method for manufacturing the same, which are suitable for healing an infected wound or a wound where there is a danger of infection. By formation of a drug-containing layer separated from a foam layer, the polyurethane foam dressing enables drugs to be favorably delivered to the wound, regardless of secretion/nonsecretion of exudates and the amount of exudates secreted. The method comprises forming a nonporous waterproof polyurethane film layer, forming a tacky gel-like polyurethane foam layer, laminating the polyurethane foam layer on the polyurethane film layer, and forming a drug-containing layer. The polyurethane foam dressing is capable of preventing drug waste which results from addition of excessive drugs, based on favorable release of drugs via the drug-containing layer separated from a foam layer. In addition, the polyurethane foam dressing enables favorable drug release, regardless of secretion/nonsecretion of exudates and the amount of exudates, thus rendering the drug to be sufficiently delivered even to wounds hardly secreting exudates as well as wounds in a middle or late stage.
摘要翻译：本文公开了一种包含药物含有层的聚氨酯泡沫敷料及其制造方法，其适用于治疗感染伤口或存在感染危险的伤口。通过形成从泡沫层分离的含药层，不管分泌物的分泌/分泌和分泌的渗出物的量如何，聚氨酯泡沫敷料使得药物能够有利地递送到伤口。该方法包括形成无孔防水聚氨酯膜层，形成粘性凝胶状聚氨酯泡沫层，将聚氨酯泡沫层层压在聚氨酯膜层上，形成含药层。基于通过从泡沫层分离的含药层有利地释放药物，聚氨酯泡沫敷料能够防止由于添加过量药物而引起的药物浪费。此外，聚氨酯泡沫敷料能够有效地释放药物，而不管渗出物的分泌/分泌物和渗出物的量如何，因此即使在中期或晚期难以分泌渗出物以及伤口的伤口也能充分地输送药物。

2. 发明申请

WO2008156285A1 METHOD FOR PRODUCING HYDROPHILIC FOAM DRESSING AND HYDROPHILIC FOAM DRESSING PRODUCED THEREBY 审中-公开
标题翻译：生产水泥发泡软管的方法和生产水泥发泡软管
公开(公告)号：WO2008156285A1
公开(公告)日：2008-12-24
申请号：PCT/KR2008/003414
申请日：2008-06-17
申请人： WONBIOGEN CO., LTD. , KUMOH NATIONAL INSTITUTE OF TECHNOLOGY INDUSTRY-ACADEMIC COOPERATION FOUNDATION , LEE, Hyang Lim , KIM, Won Il , JANG, Seoung Wan , KIM, Woo Kyun , KWON, Oh Hyeong
发明人： KIM, Won Il , JANG, Seoung Wan , KIM, Woo Kyun , KWON, Oh Hyeong
IPC分类号： A61F13/02
CPC分类号： A61F13/00991 , A61F13/0283 , A61F2013/00634 , A61L15/26 , A61L15/425 , B32B5/18 , B32B27/08 , B32B27/40 , C08L75/04
摘要： Disclosed herein is a method for producing a polyurethane foam dressing that protects injuries such as wounds or burns and is useful for wound healing. More particularly, the present invention provides a method for manufacturing a polyurethane foam dressing with remarkably improved productivity and processing efficiency, which can improve physical properties of the polyurethane foam dressing. The method comprises: preparing a moisture permeable waterproof polyurethane film layer; preparing a polyurethane prepolymer; preparing a polyurethane foaming mixture; obtaining a tacky gel type polyurethane foam layer; laminating the tacky gel type polyurethane foam layer on the polyurethane film layer; and winding the produced polyurethane foam dressing in a roll form and then ageing the foam dressing. The method further includes, impregnating the polyurethane foam with a moisturizer and drying the foam and, then, treating the foam with oxygen plasma to modify a surface of the foam dressing, thereby improving absorption rate of the foam dressing. The method of the present invention has advantages such as remarkably improved productivity and processing efficiency allowing mass production of foam dressings, thereby considerably reducing production costs and enabling supply of low cost foam dressings with improved physical properties.
摘要翻译：本文公开了一种用于生产聚氨酯泡沫敷料的方法，其用于保护伤口如伤口或烧伤，并且可用于伤口愈合。更具体地，本发明提供了一种制造聚氨酯泡沫敷料的方法，其具有显着提高的生产率和加工效率，其可改善聚氨酯泡沫敷料的物理性能。该方法包括：制备透湿防水聚氨酯膜层; 制备聚氨酯预聚物; 制备聚氨酯发泡混合物; 得到粘性凝胶型聚氨酯泡沫层; 在聚氨酯膜层上层压粘性凝胶型聚氨酯泡沫层; 并将生产的聚氨酯泡沫敷料卷成卷状，然后老化泡沫敷料。该方法还包括：用保湿剂浸渍聚氨酯泡沫并干燥泡沫，然后用氧等离子体处理泡沫以改变泡沫敷料的表面，从而提高泡沫敷料的吸收速率。本发明的方法具有显着提高的生产率和加工效率，从而大量生产泡沫敷料，从而显着降低了生产成本，并且能够提供具有改进物理性能的低成本泡沫敷料。

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