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1. 发明申请

WO1989006485A1 PROCESS FOR OBTAINING INTACT FERTILE ARABIDOPSIS PLANTS FROM PROTOPLASTS 审中-公开
标题翻译：从原始植物获取积极的阿拉伯种植体的方法
公开(公告)号：WO1989006485A1
公开(公告)日：1989-07-27
申请号：PCT/DE1989000043
申请日：1989-01-23
申请人： INSTITUT FÜR GENBIOLOGISCHE FORSCHUNG BERLIN GMBH , DAMM, Brigitte , WILLMITZER, Lothar
发明人： INSTITUT FÜR GENBIOLOGISCHE FORSCHUNG BERLIN GMBH
IPC分类号： A01G07/00
CPC分类号： C12N15/8206 , A01H4/00 , C12N5/04
摘要： In a regeneration process, new Arabidopsis plants are obtained from protoplasts isolated from differentiated tissues, undifferentiated tissues and various organs of Arabidopsis plants which are embedded in a polymer matrix and then cultured in the dark under constant illumination during a photoperiod. The process is used to obtain new Arabidopsis mutants and their genetic complements. The genetic material is transferred directly to the plant cells by incubating the DNA to be transformed together with Arabidopsis protoplasts in suitable incubation media.

2. 发明公开

EP1135480A1 PROMOTOREN ZUR GENEXPRESSION IN WURZELN VON PFLANZEN 审中-公开
标题翻译：基因表达的启动子植物的根
公开(公告)号：EP1135480A1
公开(公告)日：2001-09-26
申请号：EP99959279.3
申请日：1999-11-16
申请人： ETH Zürich , Riesmeier, Jörg , Willmitzer, Lothar
发明人： RIESMEIER, Jörg , WILLMITZER, Lothar , BUCHER, Marcel
IPC分类号： C12N15/11 , C12N15/29 , C12N15/82 , C12N1/21 , C12N5/10 , A01H5/06 , A01H5/00 , A01H5/10 , C12Q1/68
CPC分类号： C12N15/8227 , C07K14/415
摘要： The present invention relates to promoters effecting root-specific expression of coding nucleotide sequences controlled thereby and expression cassettes, recombinant vectors and microorganisms that contain such promoters. The invention also relates to transformed transgenic plants, in addition to a method for the production and a method for the isolation of root-specific promoters.

3. 发明申请

WO2008077635A8 DETERMINATION AND PREDICTION OF THE EXPRESSION OF TRAITS OF PLANTS FROM THE METABOLITE PROFILE AS A BIOMARKER 审中-公开
标题翻译：从生物标志物的代谢物形态表达植物的行为的确定和预测
公开(公告)号：WO2008077635A8
公开(公告)日：2008-09-04
申请号：PCT/EP2007011392
申请日：2007-12-21
申请人： MAX PLANCK GESELLSCHAFT , ALTMANN THOMAS , WILLMITZER LOTHAR , SELBIG JOACHIM , MEYER RHONDA C , STEINFATH MATTHIAS , LISEC JAN , FIEHN OLIVER
发明人： ALTMANN THOMAS , WILLMITZER LOTHAR , SELBIG JOACHIM , MEYER RHONDA C , STEINFATH MATTHIAS , LISEC JAN , FIEHN OLIVER
IPC分类号： G01N30/72 , G01N33/50
CPC分类号： G01N33/5097 , G01N30/7206
摘要： The present invention relates to a method for determining the correlation between the metabolite profiles (MPs) and the expression or potential for expression of a trait of a group of plants, and further to a method for determining or predicting the expression of a trait of a plant by taking advantage of the determined MP of said plant and a determined correlation between the MPs and the expression or potential for the expression of said trait in a group of plants. Particularly, the present invention relates to a method for determining or predicting the biomass production/growth rate of a plant by taking advantage of the determined MP of said plant and a determined correlation between the MPs and the biomass production/growth rate or the potential for biomass production/growth rate of a group of plants. The present invention also relates to a method for breeding of a plant that takes advantage of a method of determining the expression or potential for expression of a trait of said plant according to any one of the methods as disclosed, and selecting said plant on the basis of the expression or potential for expression of said trait. Furthermore, the present invention relates to a method for identifying quantitative trait loci (QTLs) for a trait or for the potential for expression of a trait of a group of plants comprising the step of identifying QTLs for metabolite combinations showing correlation with the expression or potential for expression of said trait of said group of plants. The present invention also relates to and a method for identifying a candidate gene involved in the determination of expression or potential for expression of a trait of a plant comprising the step of isolating a gene corresponding to any one of the QTLs as identified by the corresponding method of the present invention. Additionally, the present invention relates to a method of screening for a plant that exhibits a desired expression or potential for expression of a trait as well as to a method of determining whether a treatment influences the expression or potential for expression of a trait of a plant.
摘要翻译：本发明涉及一种用于确定代谢物谱（MPs）与一组植物的性状的表达或潜在性之间的相关性的方法，并且还涉及用于确定或预测植物的性状的表达的方法植物通过利用所确定的所述植物的MP和MP之间的确定的相关性以及在一组植物中表达所述性状的表达或潜力。特别地，本发明涉及通过利用所确定的所述植物的MP和确定的MP与生物量生产/生长速率之间的相关性来确定或预测植物的生物量生产/生长速率的方法或潜在的一组植物的生物量生产/生长速率。本发明还涉及一种植物育种方法，其利用根据所公开的方法中的任一方法确定所述植物的性状的表达或潜力的方法的方法，并且基于所述方法选择所述植物表达或表达所述性状的潜力。此外，本发明涉及用于鉴定一组性状或用于表达一组植物的性状的潜力的数量性状基因座（QTL）的方法，包括鉴定与表达或潜在相关的代谢物组合的QTL的步骤用于表达所述植物组的所述性状。本发明还涉及用于鉴定涉及用于表达植物性状的表达或潜在性的候选基因的方法，包括分离与通过相应方法鉴定的任何一个QTL相对应的基因的步骤的本发明。另外，本发明涉及一种筛选表现出性状表达所需表达或潜力的植物的方法以及确定处理是否影响植物性状的表达或潜力的方法。

4. 发明申请

WO1994004692A1 DNA SEQUENCES WHICH LEAD TO THE FORMATION OF POLYFRUCTANS (LEVANS), PLASMIDS CONTAINING THESE SEQUENCES AS WELL AS A PROCESS FOR PREPARING TRANSGENIC PLANTS 审中-公开
标题翻译：导致形成聚赖氨酸（LEVANS）的DNA序列，包含这些序列的PLASMIDS作为制备转基因植物的方法
公开(公告)号：WO1994004692A1
公开(公告)日：1994-03-03
申请号：PCT/EP1993002110
申请日：1993-08-09
申请人： INSTITUT FÜR GENBIOLOGISCHE FORSCHUNG BERLIN GMBH , RÖBER, Manuela , GEIER, Gebhardt , GEIDER, Klaus , WILLMITZER, Lothar
发明人： INSTITUT FÜR GENBIOLOGISCHE FORSCHUNG BERLIN GMBH
IPC分类号： C12N15/82
CPC分类号： C12N9/1055 , C12N15/8246
摘要： There are described DNA sequences, which lead to the formation of polyfructans (levans), plasmids containing theses DNA sequences, as well as a process using these plasmids for preparing transgenic plants with polyfructan (levan) expression.
摘要翻译：描述了DNA序列，其导致形成多聚果糖（levans），含有这些DNA序列的质粒，以及使用这些质粒制备具有多聚果糖（levan）表达的转基因植物的方法。

5. 发明申请

WO1992001042A1 TRANSGENIC PLANTS EXPRESSING INDUSTRIAL ENZYMES 审中-公开
标题翻译：显示工业酶的转基因植物
公开(公告)号：WO1992001042A1
公开(公告)日：1992-01-23
申请号：PCT/DK1991000194
申请日：1991-07-05
申请人： NOVO NORDISK A/S , WILLMITZER, Lothar , SONNEWALD, Uwe , RÖBER, Manuela , CARLSEN, Soren, Knud
发明人： NOVO NORDISK A/S
IPC分类号： C12N05/14
CPC分类号： C12N9/6481 , C12N9/00 , C12N9/58 , C12N15/8257
摘要： A transgenic plant comprises an inserted DNA sequence encoding an industrial enzyme which is heterologous to said plant, with the exception of enzymes conferring improved growth properties or desirable physical characteristics to living plants producing them. The transgenic plant may be used for the production of industrial enzymes by cultivating a seed or other propagatable part thereof, and the enzyme may then be recovered from the plant.
摘要翻译：转基因植物包括编码与所述植物异源的工业酶的插入DNA序列，除了赋予生产它们的生物植物改善的生长特性或期望的物理特性的酶以外。转基因植物可用于通过种植种子或其它可传播的部分来生产工业酶，然后可以从植物中回收酶。

6. 发明专利

DE19852757A1 未知
公开(公告)号：DE19852757A1
公开(公告)日：2000-05-18
申请号：DE19852757
申请日：1998-11-16
申请人： ETH ZUERICH ZUERICH , WILLMITZER LOTHAR , RIESMEIER JOERG
发明人： BUCHER MARCEL , RIESMEIER JOERG , WILLMITZER LOTHAR
IPC分类号： A01H5/00 , C07K14/415 , C12N1/21 , C12N5/10 , C12N15/09 , C12N15/82 , C12Q1/68 , C12N15/11 , A01H5/06
摘要： The present invention relates to promoters effecting root-specific expression of coding nucleotide sequences controlled thereby and expression cassettes, recombinant vectors and microorganisms that contain such promoters. The invention also relates to transformed transgenic plants, in addition to a method for the production and a method for the isolation of root-specific promoters.

7. 发明专利

CA2036103A1 PLASMIDS FOR THE PREPARATION OF TRANSGENIC PLANTS HAVING A MODIFIED HABIT AND YIELD 未知
公开(公告)号：CA2036103A1
公开(公告)日：1991-08-14
申请号：CA2036103
申请日：1991-02-11
申请人： WILLMITZER LOTHAR , SONNEWALD UWE , VON SCHAEVEN ANTJE , HOECHST SCHERLING AGREVO GMBH
发明人： WILLMITZER LOTHAR , SONNEWALD UWE , VON SCHAEVEN ANTJE
IPC分类号： A01H5/00 , C07K14/81 , C12N5/10 , C12N9/26 , C12N15/09 , C12N15/56 , C12N15/82 , C12N15/64 , C12N5/04
摘要： There is disclosed plasmids for the preparation of transgenic plants, as well as the plants, that are modified through the transfer and the expression of genes influencing the sugar metabolism or the sugar partitioning within a plant, which are localised on these plasmids. The transferred genes cause a modified distribution of assimilates in the transgenic plant which result in significant changes in habit, such as size, leaf shape, internode separation and root formation, as well as improvements in yield. Plasmids are also described which enable foreign proteins to be directed into the vacuoles of transgenic plants.

8. 发明申请

WO2008077635A1 DETERMINATION AND PREDICTION OF THE EXPRESSION OF TRAITS OF PLANTS FROM THE METABOLITE PROFILE AS A BIOMARKER 审中-公开
标题翻译：作为生物标记物的代谢物谱中植物性状表达的测定和预测
公开(公告)号：WO2008077635A1
公开(公告)日：2008-07-03
申请号：PCT/EP2007/011392
申请日：2007-12-21
申请人： MAX-PLANCK-GESELLSCHAFT ZUR FÖRDERUNG DER WISSENSCHAFTEN E.V. , ALTMANN, Thomas , WILLMITZER, Lothar , SELBIG, Joachim , MEYER, Rhonda, C. , STEINFATH, Matthias , LISEC, Jan , FIEHN, Oliver
发明人： ALTMANN, Thomas , WILLMITZER, Lothar , SELBIG, Joachim , MEYER, Rhonda, C. , STEINFATH, Matthias , LISEC, Jan , FIEHN, Oliver
IPC分类号： G01N30/72 , G01N33/50
CPC分类号： G01N33/5097 , G01N30/7206
摘要： The present invention relates to a method for determining the correlation between the metabolite profiles (MPs) and the expression or potential for expression of a trait of a group of plants, and further to a method for determining or predicting the expression of a trait of a plant by taking advantage of the determined MP of said plant and a determined correlation between the MPs and the expression or potential for the expression of said trait in a group of plants. Particularly, the present invention relates to a method for determining or predicting the biomass production/growth rate of a plant by taking advantage of the determined MP of said plant and a determined correlation between the MPs and the biomass production/growth rate or the potential for biomass production/growth rate of a group of plants. The present invention also relates to a method for breeding of a plant that takes advantage of a method of determining the expression or potential for expression of a trait of said plant according to any one of the methods as disclosed, and selecting said plant on the basis of the expression or potential for expression of said trait. Furthermore, the present invention relates to a method for identifying quantitative trait loci (QTLs) for a trait or for the potential for expression of a trait of a group of plants comprising the step of identifying QTLs for metabolite combinations showing correlation with the expression or potential for expression of said trait of said group of plants. The present invention also relates to and a method for identifying a candidate gene involved in the determination of expression or potential for expression of a trait of a plant comprising the step of isolating a gene corresponding to any one of the QTLs as identified by the corresponding method of the present invention. Additionally, the present invention relates to a method of screening for a plant that exhibits a desired expression or potential for expression of a trait as well as to a method of determining whether a treatment influences the expression or potential for expression of a trait of a plant.
摘要翻译：本发明涉及用于确定代谢物谱（MP）与一组植物性状表达或表达潜力之间的相关性的方法，并且还涉及用于确定通过利用所确定的所述植物的MP和所确定的MP与所述性状在一组植物中的表达或表达潜力之间的相关性来预测植物性状的表达。具体而言，本发明涉及一种通过利用所确定的所述植物的MP和所确定的MP与生物量生产/生长速率之间的相关性或可能性来确定或预测植物的生物量生产/生长速率的方法一组植物的生物量产量/增长率。本发明还涉及利用根据所公开的任何一种方法确定所述植物性状表达或表达潜力的方法并且基于所述方法选择所述植物的方法所述性状的表达或表达潜力。此外，本发明涉及用于鉴定性状的数量性状基因座（QTL）或用于表达植物组的性状的潜力的方法，其包括鉴定代谢物组合的QTL的步骤，其显示与表达或潜力的相关性用于表达所述植物组的所述性状。本发明还涉及鉴定参与确定植物性状表达或表达潜力的候选基因的方法，该方法包括以下步骤：分离相应于由相应方法鉴定的任何一个QTL的基因的本发明。另外，本发明涉及筛选表现出期望表达或性状表达潜力的植物的方法，以及确定处理是否影响植物性状的表达或表达潜力的方法

9. 发明申请

WO1998023734A1 POLYMER MEMBRANE WITH ENZYMES LOCALISED IN THE MEMBRANE AND PROCESS FOR PREPARING PRODUCTS BY REACTIONS THAT TAKE PLACE IN POLYMER MEMBRANES 审中-公开
标题翻译：高分子膜与本地化的膜酶和方法，为产品意味着聚合物膜排水降反应中生产出
公开(公告)号：WO1998023734A1
公开(公告)日：1998-06-04
申请号：PCT/DE1997002736
申请日：1997-11-22
申请人： GKSS-FORSCHUNGSZENTRUM GEESTHACHT GMBH , MAX-PLANCK-GESELLSCHAFT ZUR FÖRDERUNG DER WISSENSCHAFTEN e.V. , PAUL, Dieter , BECKER, Margot , OECHEL, Annett , PAPRA, Alexander , NEDELMANN, Heinz , WEIGEL, Thomas , ULBRICHT, Mathias , HICKE, Hans-Georg , WILLMITZER, Lothar
发明人： GKSS-FORSCHUNGSZENTRUM GEESTHACHT GMBH , MAX-PLANCK-GESELLSCHAFT ZUR FÖRDERUNG DER WISSENSCHAFTEN e.V.
IPC分类号： C12N11/08
CPC分类号： C12N11/00 , C12N11/08
摘要： A polymer membrane (10) in whose pores are localised enzymes for biocatalytic purposes is formed by open pores (11) that extend through the membrane (10) with cylindrical to conical pores (10) in the cross-section of the membrane (10). At least the pore length (13) and/or pore cross-section (16) are adjusted depending on the type of a substrate (15) supplied to the membrane (10) and on a product (16) formed from the substrate (15) by the enzymes (12). Also disclosed is a process in which the enzyme charge density in the pores of the membrane is adjusted depending on pore diameter and pore length, so that the transverse diffusion of the substrate that flows through the pores up to the enzymes arranged in a side wall area of the pores be an adjustable parameter of the desired chain length and/or ramification of the thus obtained macromolecular product.
摘要翻译：它是一种聚合物膜（10），其中，用于生物催化的目的毛孔酶被本地化建议。聚合物膜（10）由膜片（10）形成穿过开孔（11）在所述膜（10），直到锥形孔（10）的横截面的基本上为圆柱形的，其中，至少所述孔的长度（13）和/或所述孔的横截面（ 16）根据（10）施加到基板（15膜的类型）和的（从基板15）（通过酶的手段12）产物（16）而形成，也可调节的，它提出了一种方法，其中的密度酶加载在膜的孔eingesellt作为孔直径的函数，并且所述孔的长度，使得所述孔穿过所述基板的交叉扩散，从而到达基本上布置在所述孔的侧壁部分内切酶的可调节参数的以实现所需的链长和/或分支的是大分子产品。

10. 发明申请

WO1997045547A2 LOCALISED CELL DEATH IN PLANTS 审中-公开
标题翻译：属地化细胞死亡植物
公开(公告)号：WO1997045547A2
公开(公告)日：1997-12-04
申请号：PCT/EP1997002749
申请日：1997-05-27
申请人： MAX-PLANCK-GESELLSCHAFT ZUR FÖRDERUNG DER WISSENSCHAFTEN E.V. , WILLMITZER, Lothar , MÜLLER-RÖBER, Bernd
发明人： MAX-PLANCK-GESELLSCHAFT ZUR FÖRDERUNG DER WISSENSCHAFTEN E.V.
IPC分类号： C12N15/82
CPC分类号： C12N9/2408 , C12N9/1055 , C12N15/8263 , C12N15/8279 , C12N15/8289
摘要： The invention relates to nucleic acid molecules for production of localised cell death in plants, and vectors containing said nucleic acid molecules. It also relates to plant cells and plants which are genetically modified by said nucleic acid molecules.
摘要翻译：将描述的核酸分子在植物中产生的局部细胞死亡，以及含有这样的核酸分子的载体，以及被遗传与这样的核酸分子修饰的植物细胞和植物。

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