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1. 发明申请

US20180104655A1 Improvements In and Relating to Polymeric Membranes 审中-公开
公开(公告)号：US20180104655A1
公开(公告)日：2018-04-19
申请号：US15562663
申请日：2016-03-24
申请人： WHATMAN GMBH
发明人： Marcel Thieme , Klaus Hochleitner , Suzana Kiel , Alexander Schenk , Wolfgang Thamm , Daniela Katarzynski , Georg Peter Danisch
IPC分类号： B01D67/00 , B01D71/20 , B01D65/02
CPC分类号： B01D67/0088 , B01D65/02 , B01D67/0009 , B01D67/0013 , B01D67/0095 , B01D71/14 , B01D71/20 , B01D2321/30 , B01D2323/08 , B01D2323/42
摘要： Disclosed is a method and apparatus for manufacturing a continuous web of polymeric membrane and for continuous downstream processing of said web. The apparatus (10) comprises: a casting station (20) for casting the continuous web (M); a carrier (24) for carrying the web downstream; a membrane drier (30) downstream of the carrier, for drying the web; and a brushing station (40) downstream of the drier for brushing the web. Said drier is located immediately downstream of the carrier, and upstream of said brushing station. The apparatus (10) further includes an additional drying station (50) downstream of the brushing station (40). Brushing after drying retains more surfactant in the membrane which is useful for certain applications. In addition, initial drying eliminates virtually all solvents from the membrane, but leaves some non-solvent (e.g. water) within it, which in turn fixes the surfactant on the nitrocellulose fibers, which improves significantly the consistency and reproducibility of the membrane.

2. 发明授权

US09707523B2 Membrane filter including bile acid and a method of manufacturing the same 有权
公开(公告)号：US09707523B2
公开(公告)日：2017-07-18
申请号：US14380488
申请日：2013-02-22
申请人： WHATMAN GMBH
发明人： Klaus Hochleitner , Suzana Kiel
IPC分类号： B01D71/12 , B01D71/16 , B01D71/20 , B01D67/00 , B01D69/02 , C12Q1/24 , G01N1/40
CPC分类号： B01D71/12 , B01D67/0002 , B01D67/0086 , B01D67/0088 , B01D67/0095 , B01D69/02 , B01D71/16 , B01D71/20 , B01D2325/08 , B01D2325/12 , C12Q1/24 , G01N2001/4088
摘要： A membrane filter 26 is disclosed comprising cellulous material 23 allowing the transition of fluid therethrough, and, in a substantially dry state, said membrane comprising also a salt of deoxycholic acid. Optionally, the air side of the membrane (the side facing away from the screen or belt used to manufacture the membrane) faces the sample fluid during use of the membrane. A method of manufacture of the membrane material is disclosed also, employing deoxycholic acid as a surfactant, to improve the recovery rate of the membrane filter in use.

3. 发明申请

US20170115287A1 IMPROVEMENTS IN AND RELATING TO LATERAL FLOW TESTING 审中-公开
公开(公告)号：US20170115287A1
公开(公告)日：2017-04-27
申请号：US15300558
申请日：2015-03-17
申请人： Whatman GmbH
发明人： Alexander Schenk , Klaus Hochleitner , Suzana Kiel , Marcel Thieme , Wei Sun
IPC分类号： G01N33/558 , G01N33/52
CPC分类号： G01N33/558 , G01N33/525
摘要： In a lateral flow test (LFT) device, the liquid conduit element 20 is formed from a substrate 21, 22 or 24 having at least two layers, including a first layer 21b, 22b or 24b not exceeding 75 μm in thickness formed from a porous material for wicking liquid, and a second layer 21a,22a or 24a of additional thickness formed from a generally non-porous polymer material acting as backing layer. The layered arrangement is incorporated into an LFT device to reduce sample volume requirements.

4. 发明申请

US20150377872A1 MEDICAL DIAGNOSTIC TEST SYSTEMS, AND A MATRIX THEREFOR 审中-公开
标题翻译：医学诊断测试系统及其基础
公开(公告)号：US20150377872A1
公开(公告)日：2015-12-31
申请号：US14766397
申请日：2014-02-03
申请人： WHATMAN GMBH
发明人： Klaus HOCHLEITNER , Suzana KIEL , Alexander SCHENK , Wei SUN
IPC分类号： G01N33/543
CPC分类号： G01N33/5436 , B01D69/02 , B01D69/06 , B01D69/10 , B01D69/12 , B01D71/10 , B01D71/20 , B01D2325/04 , B01L3/5023 , B01L2200/12 , B01L2300/0825 , G01N33/548
摘要： The invention discloses a reduced thickness membrane matrix for carrying liquids consisting of a cellulosic material with a thickness of between 10 and 50 μm and a pore size between 0.1 μm and 20 μm for use with diagnostic tests such as lateral flow tests, thereby reducing the amount of test reagents required.
摘要翻译：本发明公开了一种减小厚度的膜基质，用于承载由纤维素材料组成的液体，其厚度为10至50μm，孔径为0.1μm至20μm，用于诊断测试如横向流动测试，从而减少了量的测试试剂。

5. 发明申请

US20150027945A1 MEMBRANE FILTER INCLUDING BILE ACID AND A METHOD OF MANUFACTURING THE SAME 有权
标题翻译：包含双酸的膜过滤器及其制造方法
公开(公告)号：US20150027945A1
公开(公告)日：2015-01-29
申请号：US14380488
申请日：2013-02-22
申请人： WHATMAN GMBH
发明人： Klaus Hochleitner , Suzana Kiel
IPC分类号： B01D71/12 , B01D71/20 , B01D67/00 , B01D71/16
CPC分类号： B01D71/12 , B01D67/0002 , B01D67/0086 , B01D67/0088 , B01D67/0095 , B01D69/02 , B01D71/16 , B01D71/20 , B01D2325/08 , B01D2325/12 , C12Q1/24 , G01N2001/4088
摘要： A membrane filter 26 is disclosed comprising cellulous material 23 allowing the transition of fluid therethrough, and, in a substantially dry state, said membrane comprising also a salt of deoxycholic acid. Optionally, the air side of the membrane (the side facing away from the screen or belt used to manufacture the membrane) faces the sample fluid during use of the membrane. A method of manufacture of the membrane material is disclosed also, employing deoxycholic acid as a surfactant, to improve the recovery rate of the membrane filter in use.
摘要翻译：公开了一种膜过滤器26，其包括允许流体从其中过渡的纤维素材料23，并且在基本干燥的状态下，所述膜还包含脱氧胆酸盐。可选地，膜的空气侧（背离用于制造膜的筛网或带的一侧）在使用膜期间面向样品流体。还公开了使用脱氧胆酸作为表面活性剂的膜材料的制造方法，以提高膜过滤器在使用中的回收率。

6. 发明申请

WO2014122094A1 MEDICAL DIAGNOSTIC TEST SYSTEMS, AND A MATRIX THEREFOR 审中-公开
标题翻译：医学诊断测试系统及其基础
公开(公告)号：WO2014122094A1
公开(公告)日：2014-08-14
申请号：PCT/EP2014/052051
申请日：2014-02-03
申请人： WHATMAN GMBH
发明人： HOCHLEITNER, Klaus , KIEL, Suzana , SCHENK, Alexander , SUN, Wei
IPC分类号： B01D71/20 , B01D69/10 , B01D69/06 , B01L3/00 , B01D69/02 , B01D69/12 , B01D71/10
CPC分类号： G01N33/5436 , B01D69/02 , B01D69/06 , B01D69/10 , B01D69/12 , B01D71/10 , B01D71/20 , B01D2325/04 , B01L3/5023 , B01L2200/12 , B01L2300/0825 , G01N33/548
摘要： The invention discloses a reduced thickness membrane matrix for carrying liquids consisting of a cellulosic material with a thickness of between10 and 50 µm and a pore size between 0.1 µm and 20 µm for use with diagnostic tests such as lateral flow tests, thereby reducing the amount of test reagents required.
摘要翻译：本发明公开了一种用于承载由纤维素材料组成的厚度为10μm至50μm，孔径为0.1μm至20μm的液体的减小厚度的膜基质，用于诊断试验如横向流动试验，从而减少了测试试剂需要。

7. 发明申请

WO2015150067A1 IMPROVEMENTS IN AND RELATING TO LATERAL FLOW TESTING 审中-公开
标题翻译：改进和相关的横向流量测试
公开(公告)号：WO2015150067A1
公开(公告)日：2015-10-08
申请号：PCT/EP2015/055579
申请日：2015-03-17
申请人： WHATMAN GMBH
发明人： SCHENK, Alexander , HOCHLEITNER, Klaus , KIEL, Suzana , THIEME, Marcel , SUN, Wei
IPC分类号： G01N33/52 , G01N33/558
CPC分类号： G01N33/558 , G01N33/525
摘要： In a lateral flow test (LFT) device, the liquid conduit element 20 is formed from a substrate 21, 22 or 24 having at least two layers, including a first layer 21b, 22b or 24b not exceeding 75 µm in thickness formed from a porous material for wicking liquid, and a second layer 21a, 22a or 24a of additional thickness formed from a generally non-porous polymer material acting as backing layer. The layered arrangement is incorporated into an LFT device to reduce sample volume requirements.
摘要翻译：在侧向流动试验（LFT）装置中，液体导管元件20由具有至少两层的基底21,22或24形成，包括不超过75μm的第一层21b，22b或24b，其厚度由多孔用于芯吸液体的材料和由用作背衬层的通常无孔聚合物材料形成的附加厚度的第二层21a，22a或24a。分层布置被并入LFT装置以减少样品体积要求。

8. 发明申请

WO2016156250A1 IMPROVEMENTS IN AND RELATING TO POLYMERIC MEMBRANES 审中-公开
标题翻译：改进和相关于聚合物膜
公开(公告)号：WO2016156250A1
公开(公告)日：2016-10-06
申请号：PCT/EP2016/056667
申请日：2016-03-24
申请人： WHATMAN GMBH
发明人： THIEME, Marcel , HOCHLEITNER, Klaus , KIEL, Suzana , SCHENK, Alexander , THAMM, Wolfgang , KATARZYNSKI, Daniela , DANISCH, Georg Peter
IPC分类号： B01D65/02 , B01D67/00 , B01D71/14
CPC分类号： B01D67/0088 , B01D65/02 , B01D67/0009 , B01D67/0013 , B01D67/0095 , B01D71/14 , B01D71/20 , B01D2321/30 , B01D2323/08 , B01D2323/42
摘要： Disclosed is a method and apparatus for manufacturing a continuous web of polymeric membrane and for continuous downstream processing of said web. The apparatus (10) comprises: a casting station (20) for casting the continuous web (M);a carrier (24) for carrying the web downstream; a membrane drier (30) downstream of the carrier, for drying the web; and a brushing station (40) downstream of the drier for brushing the web. Said drier is located immediately downstream of the carrier, and upstream of said brushing station. The apparatus (10) further includes an additional drying station (50) downstream of the brushing station (40). Brushing after drying retains more surfactant in the membrane which is useful for certain applications. In addition, initial drying eliminates virtually all solvents from the membrane, but leaves some non-solvent (e.g. water) within it, which in turn fixes the surfactant on the nitrocellulose fibers, which improves significantly the consistency and reproducibility of the membrane.
摘要翻译：公开了一种用于制造聚合物膜的连续幅材并用于所述幅材的连续下游处理的方法和装置。装置（10）包括：用于铸造连续卷材（M）的铸造工位（20）;用于在下游承载纸幅的载体（24）; 在所述载体的下游的膜干燥器（30），用于干燥所述幅材; 以及在干燥器下游的刷洗站（40），用于刷涂网。所述干燥器位于所述载体的紧邻的下游，并且位于所述刷洗站的上游。所述设备（10）还包括在刷洗站（40）下游的另外的干燥站（50）。干燥后刷洗在膜中保留更多的表面活性剂，可用于某些应用。此外，初始干燥几乎消除了所有来自膜的溶剂，但在其中留下一些非溶剂（例如水），其又将表面活性剂固定在硝化纤维素纤维上，这显着改善了膜的稠度和再现性。

9. 发明申请

WO2013127709A1 MEMBRANE FILTER INCLUDING BILE ACID AND A METHOD OF MANUFACTURING THE SAME 审中-公开
标题翻译：包含胆酸的膜过滤器及其制造方法
公开(公告)号：WO2013127709A1
公开(公告)日：2013-09-06
申请号：PCT/EP2013/053620
申请日：2013-02-22
申请人： WHATMAN GMBH
发明人： HOCHLEITNER, Klaus , KIEL, Suzana
IPC分类号： B01D69/02 , B01D71/16 , B01D71/20 , C12Q1/10 , C12Q1/24
CPC分类号： B01D71/12 , B01D67/0002 , B01D67/0086 , B01D67/0088 , B01D67/0095 , B01D69/02 , B01D71/16 , B01D71/20 , B01D2325/08 , B01D2325/12 , C12Q1/24 , G01N2001/4088
摘要： A membrane filter 26 is disclosed comprising cellulous material 23 allowing the transition of fluid therethrough, and, in a substantially dry state, said membrane comprising also a salt of deoxycholic acid. Optionally, the air side of the membrane (the side facing away from the screen or belt used to manufacture the membrane) faces the sample fluid during use of the membrane. A method of manufacture of the membrane material is disclosed also, employing deoxycholic acid as a surfactant, to improve the recovery rate of the membrane filter in use.
摘要翻译：公开了一种膜过滤器26，其包括允许流体通过其过渡的纤维素材料23，并且在基本干燥的状态下，所述膜还包含脱氧胆酸盐。可选地，膜的空气侧（背离用于制造膜的筛网或带的一侧）在使用膜期间面向样品流体。还公开了使用脱氧胆酸作为表面活性剂的膜材料的制造方法，以提高膜过滤器在使用中的回收率。

10. 发明专利

AT413910T 未知
公开(公告)号：AT413910T
公开(公告)日：2008-11-15
申请号：AT01108809
申请日：2001-04-07
申请人： WHATMAN GMBH
发明人： KONSTANTIN PETER , KEMENJI DIETER , GEBHARDT MICHAEL
IPC分类号： B01D35/30 , B01D29/075

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