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1. 发明申请

WO2007143083A3 A SYSTEM AND METHODS FOR CHRONIC DISEASE MANAGEMENT AND HEALTH ASSESSMENT 审中-公开
标题翻译：一种用于慢性疾病管理和健康评估的系统和方法
公开(公告)号：WO2007143083A3
公开(公告)日：2008-04-10
申请号：PCT/US2007012924
申请日：2007-06-01
申请人： WELLDOC COMMUNICATIONS INC , SYSKO SUZANNE , NORDMANN YVES , ZILBERSHLAG SHIMON
发明人： SYSKO SUZANNE , NORDMANN YVES , ZILBERSHLAG SHIMON
IPC分类号： A61B5/00 , G06Q10/00
CPC分类号： G06Q10/00 , G06Q50/22 , G16H50/30
摘要： The systems and methods are provided to enable consistent lifestyle modifications for chronic disease management. More specifically, systems and methods are directed to performing subjective health assessments (HAs) and objective stage-of-change (SOC) status evaluations of a patient's health based on data collected from the patient. These data are collected directly from the patient via the Internet and/or portable communications devices and maintained electronically for easy access by both the patient and health care providers.
摘要翻译：提供了系统和方法，以实现对慢性病管理的一致的生活方式修改。更具体地，系统和方法旨在基于从患者收集的数据来执行患者健康的主观健康评估（HA）和客观变化阶段（SOC）状态评估。这些数据通过因特网和/或便携式通信设备直接从病人收集，并以电子方式进行维护，以便患者和保健提供者容易地进入。

2. 发明申请

WO2007143083A2 A SYSTEM AND METHODS FOR CHRONIC DISEASE MANAGEMENT AND HEALTH ASSESSMENT 审中-公开
标题翻译：一种用于慢性疾病管理和健康评估的系统和方法
公开(公告)号：WO2007143083A2
公开(公告)日：2007-12-13
申请号：PCT/US2007/012924
申请日：2007-06-01
申请人： WELLDOC COMMUNICATIONS, INC. , ZILBERSHLAG, Shimon , SYSKO, Suzanne , NORDMANN, Yves , SILBERSHLAG, Shimon
发明人： ZILBERSHLAG, Shimon , SYSKO, Suzanne , NORDMANN, Yves , SILBERSHLAG, Shimon
IPC分类号： G06Q50/00
CPC分类号： G06Q10/00 , G06F19/00 , G06Q50/22 , G16H50/30
摘要： The systems and methods are provided to enable consistent lifestyle modifications for chronic disease management. More specifically, systems and methods are directed to performing subjective health assessments (HAs) and objective stage-of-change (SOC) status evaluations of a patient's health based on data collected from the patient. These data are collected directly from the patient via the Internet and/or portable communications devices and maintained electronically for easy access by both the patient and health care providers.
摘要翻译：提供了系统和方法，以实现对慢性病管理的一致的生活方式修改。更具体地，系统和方法旨在基于从患者收集的数据来执行患者健康的主观健康评估（HA）和客观变化阶段（SOC）状态评估。这些数据通过因特网和/或便携式通信设备直接从病人收集，并以电子方式进行维护，以便患者和保健提供者容易地进入。

3. 发明申请

WO2008103827A1 SYSTEM AND METHOD FOR PROVIDING TREATMENT RECOMMENDATIONS BASED ON MODELS 审中-公开
标题翻译：基于模型提供治疗建议的系统和方法
公开(公告)号：WO2008103827A1
公开(公告)日：2008-08-28
申请号：PCT/US2008/054583
申请日：2008-02-21
申请人： WELLDOC COMMUNICATIONS, INC. , SYSKO, Ryan, A. , SYSKO, Suzanne, K. , MINOR, James, M. , IYER, Anand, K. , FLETCHER, Andrew, V.
发明人： SYSKO, Ryan, A. , SYSKO, Suzanne, K. , MINOR, James, M. , IYER, Anand, K. , FLETCHER, Andrew, V.
IPC分类号： G06F19/00
CPC分类号： G06F19/325 , G06F19/00 , G06Q50/24 , G16H50/50
摘要： Methods, computer-readable media, and systems for providing disease management. A system develops a treatment recommendation for a patient based on patient data. The system receives patient data, executes a basic model of the physiological system of the patient to generate a modified model for the patient based on the patient data, performs a statistical analysis of the patient data to detect data excursions of the parameter values; uses the modified model to determine factors causing the data excursions; and uses the model to develop a treatment recommendation to ameliorate negative effects of the disease.
摘要翻译：方法，计算机可读介质和用于提供疾病管理的系统。系统根据患者数据开发针对患者的治疗推荐。系统接收患者数据，执行病人生理系统的基本模型，根据患者数据生成患者的修改模型，对患者数据进行统计分析，检测参数值的数据偏移; 使用修改的模型来确定导致数据偏移的因素; 并使用该模型制定治疗建议，以改善疾病的负面影响。

4. 发明申请

WO2008046056A1 REDUCTION OF NONSPECIFIC BINDING IN NUCLEIC ACID ASSAYS AND NUCLEIC ACID SYNTHESIS REACTIONS 审中-公开
标题翻译：在核酸测定中减少非特异性结合和核酸合成反应
公开(公告)号：WO2008046056A1
公开(公告)日：2008-04-17
申请号：PCT/US2007/081282
申请日：2007-10-12
申请人： WELLDOC COMMUNICATIONS, INC. , MINOR, James
发明人： MINOR, James
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6832 , C12Q1/6848 , C12Q2527/143
摘要： The methods of the present invention described herein may be carried out to reduce unwanted binding of probes or other nucleic acids, and thereby reduce noise (i.e., improve signal-to-noise characteristics of signals read from these probes for their intended targets) or interference in nucleic acid assays and nucleic acid synthesis reactions. The time such assays or reactions take to complete is also reduced. The present invention relates to at least two methods: (i) methods of reducing noise and increasing efficiency in nucleic acid assays; and (ii) methods of increasing efficiency and accuracy of nucleic acid synthesis. By increasing efficiency in assays, it is meant that the reaction time to achieve a given signal is reduced and the signal strength may be increased. By increasing efficiency in nucleic acid synthesis, it is meant that greater copy numbers of accurate nucleic acids are produced in shorter periods of time.
摘要翻译：可以进行本文描述的本发明的方法以减少探针或其他核酸的不期望的结合，从而降低噪声（即，提高从这些探针读取的信号对于其预期目标的信噪比特性）或干扰在核酸测定和核酸合成反应中。这种测定或反应完成的时间也减少了。本发明涉及至少两种方法：（i）降低噪声并提高核酸测定效率的方法; 和（ii）提高核酸合成效率和准确性的方法。通过提高测定的效率，意味着实现给定信号的反应时间降低，信号强度可能增加。通过提高核酸合成的效率，意味着在更短的时间内产生更多的精确核酸拷贝数。

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