专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

WO2019023149A1 USE OF BROMODOMAIN-CONTAINING PROTEIN 9 ANTAGONISTS IN COMBINATION WITH VITAMIN D RECEPTOR AGONISTS IN DIABETES TREATMENT 审中-公开
公开(公告)号：WO2019023149A1
公开(公告)日：2019-01-31
申请号：PCT/US2018/043345
申请日：2018-07-23
申请人： SALK INSTITUTE FOR BIOLOGICAL STUDIES , EVANS, Ronald M. , DOWNES, Michael , WEI, Zong , ATKINS, Annette , YU, Ruth T.
发明人： EVANS, Ronald M. , DOWNES, Michael , WEI, Zong , ATKINS, Annette , YU, Ruth T.
IPC分类号： A61K31/592 , A61K31/593 , A61K31/4365 , A61P3/10 , A61P37/00
摘要： Methods are provided for reducing blood glucose, which utilize an agent that increases the biological activity of a vitamin D receptor (VDR) (e.g., a VDR agonist), in combination with an antagonist of bromodomain-containing protein 9 (BRD9). In some examples, such methods treat type II diabetes.

2. 发明申请

US20080270080A1 Hierarchical Real-Time Patient State Indices for Patient Monitoring 审中-公开
标题翻译：用于患者监测的分层实时患者状态指标
公开(公告)号：US20080270080A1
公开(公告)日：2008-10-30
申请号：US12097278
申请日：2006-12-14
申请人： Wei Zong
发明人： Wei Zong
IPC分类号： G06F11/00
CPC分类号： A61B5/00 , A61B5/0205 , A61B5/0402 , A61B5/14546 , A61B5/201 , A61B5/412 , A61B5/4839 , A61B5/7275 , A61B6/465 , G06Q50/22 , G16H15/00 , G16H50/20 , G16H50/50
摘要： A medical patient is monitored, and simultaneous patient state indices (416) based on function of respective organs and/or presence of respective disease in the monitored patient, i.e., the respective patient sub-area, are updated in real time. The indices are displayed, alongside actual past and predictive trend data for the index (320, 328). The screen hierarchy provides immediate access, from a screen showing an overall index and a summary of patient sub-areas, to a screen (500) offering more detail on the selected sub-area. Further immediate traversal is available to the raw measurements (420-432) supportively underlying the derived indices.
摘要翻译：监测医疗病人，并且基于各个器官的功能和/或所监视的患者中相应疾病的存在，即相应的患者子区域的患者状态指数（416）的实时更新。这些指数与索引的实际过去和预测趋势数据一起显示（320,328）。屏幕层次结构提供从显示总体索引和患者子区域的总结的屏幕到在所选子区域提供更多细节的屏幕（500）的即时访问。进一步的直接遍历可用于支持衍生指数的原始测量（420 - 432）。

3. 发明申请

US20120078131A1 ECG MONITORING WITH REDUCED FALSE ASYSTOLE ALARMS 有权
标题翻译：心电监护与减少假手机报警
公开(公告)号：US20120078131A1
公开(公告)日：2012-03-29
申请号：US13321841
申请日：2010-05-12
申请人： Wei Zong
发明人： Wei Zong
IPC分类号： A61B5/02
CPC分类号： A61B5/0452 , A61B5/021 , A61B5/024 , A61B5/0468 , A61B5/746
摘要： A patient monitor comprises: an electrocardiograph (14, 20) monitoring an electrocardiographic signal (40) of a patient (10); a secondary physiological signal monitor (16, 20) monitoring a second physiological signal (50) of the patient concurrently with the electrocardiograph monitoring the electrocardiographic signal of the patient; an alarm condition detector (42, 44) configured to detect an alarm condition based on the electrocardiographic signal of the patient; an alarm condition validator (52, 54, 56) configured to validate the alarm condition based on pulse regularity of a pulsatile component of the concurrently monitored second physiological signal of the patient; and an alarm indicator (24, 26, 58) configured to generate a human perceptible alarm conditional upon both the alarm condition detector detecting an alarm condition and the alarm condition validator validating the alarm condition.
摘要翻译：患者监护仪包括：监测患者（10）的心电图信号（40）的心电图仪（14,20）; 二次生理信号监测器（16,20），与监测患者的心电图信号的心电图仪同时监测患者的第二生理信号（50）; 被配置为基于患者的心电图信号来检测警报状况的警报状态检测器（42,44）; 一个报警条件验证器（52,54,56），被配置为基于同时监视的患者第二生理信号的脉冲分量的脉冲规律性来验证报警状况; 以及报警指示器（24,26,58），其被配置为在所述报警条件检测器检测到报警状况和所述报警条件验证器两者的情况下生成人感知报警。

4. 发明申请

US20110316704A1 SYSTEM AND METHOD FOR AUTOMATIC CAPTURE AND ARCHIVE OF CLINICALLY MEANINGFUL VITALS 有权
标题翻译：用于自动捕获和临床意义上的储存的系统和方法
公开(公告)号：US20110316704A1
公开(公告)日：2011-12-29
申请号：US13147373
申请日：2010-01-12
申请人： Larry Nielsen , Gregory H. Raber , Brian D. Gross , Wei Zong , Mohammed Saeed
发明人： Larry Nielsen , Gregory H. Raber , Brian D. Gross , Wei Zong , Mohammed Saeed
IPC分类号： G08B23/00 , G06F17/40
CPC分类号： A61B5/0002 , A61B5/0205 , A61B5/021 , A61B5/02116 , A61B5/7203 , A61B5/7221 , A61B5/7232 , G06F19/00 , G16H15/00 , G16H50/20
摘要： Medical vital signs (110) are captured, recorded, processed, and a signal quality assessment (160) is computed based on signal waveform components such as slope, amplitude, time to rise, time at peak, and degree to which signal peaks (420) and valleys (430). The signal assessment (160) may be used as a basis for rating the quality (130) of the underlying vital signal, to increase the quality of the signal by removing noisy segments and physiologically impossible peaks (424) and valleys (434), to detect a parameter value (120), to label a waveform (140), or to prompt an alarm (550) to indicate the signal has reached a critical level and issue a warning to the user of the vital data. The signal and the assessment are stored in an indexed, searchable data storage memory (590) from which the signals may be retrieved and displayed (300).
摘要翻译：医疗生命体征（110）被捕获，记录，处理，并且基于诸如斜率，振幅，上升时间，峰值时间和信号峰值的信号波形分量（420）计算信号质量评估（160））和谷（430）。信号评估（160）可以用作评估潜在生命信号的质量（130）的基础，以通过去除噪声段和生理上不可能的峰值（424）和谷（434）来增加信号的质量，以检测参数值（120），标记波形（140），或者提示警告（550）指示信号已经达到临界水平，并向使用者发出重要数据的警告。信号和评估被存储在索引的可搜索的数据存储器（590）中，从中可以检索和显示信号（300）。

5. 发明申请

US20110009714A1 HEMODYNAMIC MONITORS AND ALARMS 审中-公开
标题翻译：动物监测和报警
公开(公告)号：US20110009714A1
公开(公告)日：2011-01-13
申请号：US12919819
申请日：2009-02-02
申请人： Wei Zong
发明人： Wei Zong
IPC分类号： A61B5/02
CPC分类号： A61B5/021 , A61B5/02028 , A61B5/024 , A61B5/7264 , A61B5/7275 , G16H40/63
摘要： A hemodynamic monitoring instrument includes a processor and an output device. The processor (30) is arranged to receive a physiological parameter indicative of heart rate and a physiological parameter indicative of arterial blood pressure and is configured to compute (50) a hemodynamic parameter correlating with systemic vascular resistance (SVR) based on the received physiological parameter indicative of heart rate and the received physiological parameter indicative of arterial blood pressure. The output device includes least one of: (i) a display (24) configured to display the computed hemodynamic parameter; and (ii) an alarm (32, 34) configured to generate a perceptible signal responsive to the computed hemodynamic parameter satisfying an alarm criterion (52). The processor in some embodiments computes the hemodynamic parameter using a fuzzy membership function representing the heuristic ‘quantitative ABP measure is low AND quantitative HR measure is slightly high or high’ OR ‘quantitative ABP measure is very low’.
摘要翻译：血液动力学监测仪器包括处理器和输出装置。处理器（30）被布置成接收指示心率的生理参数和指示动脉血压的生理参数，并且被配置为基于接收到的生理参数来计算（50）与全身血管阻力（SVR）相关的血液动力学参数指示心率和接受的指示动脉血压的生理参数。输出装置包括以下中的至少一个：（i）被配置为显示所计算的血液动力学参数的显示器（24）以及（ii）响应于所述计算出的满足报警标准（52）的血液动力学参数而产生可感知信号的报警器（32,34）。在一些实施例中，处理器使用表示启发式的定量ABP测量的模糊隶属函数计算血液动力学参数，并且定量HR测量略高或高“OR”定量ABP测量非常低“。

6. 发明授权

US08989853B2 ECG monitoring with reduced false asystole alarms 有权
标题翻译： ECG监测减少了假性心脏停搏报警
公开(公告)号：US08989853B2
公开(公告)日：2015-03-24
申请号：US13321841
申请日：2010-05-12
申请人： Wei Zong
发明人： Wei Zong
IPC分类号： A61B5/04 , A61B5/0452 , A61B5/021 , A61B5/024 , A61B5/0468
CPC分类号： A61B5/0452 , A61B5/021 , A61B5/024 , A61B5/0468 , A61B5/746
摘要： A patient monitor comprises: an electrocardiograph (14, 20) monitoring an electrocardiographic signal (40) of a patient (10); a secondary physiological signal monitor (16, 20) monitoring a second physiological signal (50) of the patient concurrently with the electrocardiograph monitoring the electrocardiographic signal of the patient; an alarm condition detector (42, 44) configured to detect an alarm condition based on the electrocardiographic signal of the patient; an alarm condition validator (52, 54, 56) configured to validate the alarm condition based on pulse regularity of a pulsatile component of the concurrently monitored second physiological signal of the patient; and an alarm indicator (24, 26, 58) configured to generate a human perceptible alarm conditional upon both the alarm condition detector detecting an alarm condition and the alarm condition validator validating the alarm condition.
摘要翻译：患者监护仪包括：监测患者（10）的心电图信号（40）的心电图仪（14,20）; 二次生理信号监测器（16,20），与监测患者的心电图信号的心电图仪同时监测患者的第二生理信号（50）; 被配置为基于患者的心电图信号来检测警报状况的警报状态检测器（42,44）; 一个报警条件验证器（52,54,56），被配置为基于同时监视的患者第二生理信号的脉冲分量的脉冲规律性来验证报警状况; 以及报警指示器（24,26,58），其被配置为在所述报警条件检测器检测到报警状况和所述报警条件验证器两者的情况下生成人感知报警。

7. 发明申请

US20080214904A1 Apparatus To Measure The Instantaneous Patients' Acuity Value 有权
标题翻译：用于测量瞬时患者的敏感度值的装置
公开(公告)号：US20080214904A1
公开(公告)日：2008-09-04
申请号：US11917767
申请日：2006-06-13
申请人： Mohammed Saeed , Larry Nielsen , Joseph J. Frassica , Walid S.I. Ali , Larry J. Eshelman , Wei Zong , Omar Abdala
发明人： Mohammed Saeed , Larry Nielsen , Joseph J. Frassica , Walid S.I. Ali , Larry J. Eshelman , Wei Zong , Omar Abdala
IPC分类号： A61B5/00 , G06Q50/00 , G06F17/30
CPC分类号： A61B5/0006 , G06F19/00 , G06Q50/22 , G16H10/60 , G16H15/00 , G16H40/63 , G16H50/30
摘要： In a patient monitoring system (10), shorter interval physiological parameters and longer interval clinical data are collected from a monitored patient (12). A composite acuity score generator (70) generates or updates a composite acuity score indicative of wellbeing of the patient (12) based at least on the sensed physiological parameters and the longer interval data. A monitor (22, 56) displays current values of at least one of selected sensed physiological parameters, longer interval data, and the composite acuity score.
摘要翻译：在患者监测系统（10）中，从监测的患者（12）收集较短的间隔生理参数和更长的间隔临床数据。复合视敏度分数生成器（70）至少基于所感测的生理参数和较长的间隔数据来生成或更新指示患者（12）的健康的复合视力分数。显示器（22,56）显示所选择的感测生理参数，较长间隔数据和复合视力评分中的至少一个的当前值。

8. 发明授权

US09167968B2 Apparatus to measure the instantaneous patients' acuity value 有权
标题翻译：用于测量瞬时患者敏感度值的装置
公开(公告)号：US09167968B2
公开(公告)日：2015-10-27
申请号：US11917767
申请日：2006-06-13
申请人： Mohammed Saeed , Larry Nielsen , Joseph J. Frassica , Walid S. I. Ali , Larry J. Eshelman , Wei Zong , Omar Abdala
发明人： Mohammed Saeed , Larry Nielsen , Joseph J. Frassica , Walid S. I. Ali , Larry J. Eshelman , Wei Zong , Omar Abdala
IPC分类号： A61B5/00 , G06Q50/22 , G06F19/00
CPC分类号： A61B5/0006 , G06F19/00 , G06Q50/22 , G16H10/60 , G16H15/00 , G16H40/63 , G16H50/30
摘要： In a patient monitoring system (10), shorter interval physiological parameters and longer interval clinical data are collected from a monitored patient (12). A composite acuity score generator (70) generates or updates a composite acuity score indicative of wellbeing of the patient (12) based at least on the sensed physiological parameters and the longer interval data. A monitor (22, 56) displays current values of at least one of selected sensed physiological parameters, longer interval data, and the composite acuity score.
摘要翻译：在患者监测系统（10）中，从监测的患者（12）收集较短的间隔生理参数和更长的间隔临床数据。复合视敏度分数生成器（70）至少基于所感测的生理参数和较长的间隔数据来生成或更新指示患者（12）的健康的复合视力分数。显示器（22,56）显示所选择的感测生理参数，较长间隔数据和复合视力评分中的至少一个的当前值。

9. 发明授权

US08878677B2 System and method for automatic capture and archive of clinically meaningful vitals 有权
标题翻译：用于自动捕获和归档临床有意义的生物体的系统和方法
公开(公告)号：US08878677B2
公开(公告)日：2014-11-04
申请号：US13147373
申请日：2010-01-12
申请人： Larry Nielsen , Gregory H. Raber , Brian D. Gross , Wei Zong , Mohammed Saeed
发明人： Larry Nielsen , Gregory H. Raber , Brian D. Gross , Wei Zong , Mohammed Saeed
IPC分类号： G08B23/00 , G06F19/00 , G06F17/40 , A61B5/00 , A61B5/021 , A61B5/0205
CPC分类号： A61B5/0002 , A61B5/0205 , A61B5/021 , A61B5/02116 , A61B5/7203 , A61B5/7221 , A61B5/7232 , G06F19/00 , G16H15/00 , G16H50/20
摘要： Medical vital signs (110) are captured, recorded, processed, and a signal quality assessment (160) is computed based on signal waveform components such as slope, amplitude, time to rise, time at peak, and degree to which signal peaks (420) and valleys (430). The signal assessment (160) may be used as a basis for rating the quality (130) of the underlying vital signal, to increase the quality of the signal by removing noisy segments and physiologically impossible peaks (42) and valleys (434), to detect a parameter value (120), to label a waveform (140), or to prompt an alarm (550) to indicate the signal has reached a critical level and issue a warning to the user of the vital data. The signal and the assessment are stored in an indexed, searchable data storage memory (590) from which the signals may be retrieved and displayed (300).
摘要翻译：医疗生命体征（110）被捕获，记录，处理，并且基于诸如斜率，振幅，上升时间，峰值时间和信号峰值的信号波形分量（420）计算信号质量评估（160））和谷（430）。信号评估（160）可以用作评估潜在生命信号的质量（130）的基础，通过去除噪声段和生理上不可能的峰值（42）和谷（434）来增加信号的质量，以检测参数值（120），标记波形（140），或者提示警告（550）指示信号已经达到临界水平，并向使用者发出重要数据的警告。信号和评估被存储在索引的可搜索的数据存储器（590）中，从中可以检索和显示信号（300）。

10. 发明申请

US20200349769A1 APPARATUS AND METHOD FOR OPTIMIZED IMAGE STITCHING BASED ON OPTICAL FLOW 审中-公开
公开(公告)号：US20200349769A1
公开(公告)日：2020-11-05
申请号：US16642894
申请日：2017-09-27
申请人： Feng YUAN , Wei ZONG , Juan ZHAO , Junkai WU
发明人： Feng YUAN , Wei ZONG , Juan ZHAO , Junkai WU
IPC分类号： G06T19/00 , G06T3/40 , G06T5/50 , G06T7/246
摘要： An apparatus and method for efficient image optimized image stitching. For example, one embodiment of an apparatus comprises: feature search area identification circuitry/logic to narrow down a feature search area based on possible overlap between two image frames; feature detection circuitry/logic to identify a plurality of feature points in a first image frame of the two image frames; feature matching circuitry/logic to map one or more of the plurality of feature points from the first image frame to corresponding feature points in the right image frame; image frame stitching and blending circuitry/logic to stitch the first image frame and second image frame based on the mapping of the feature points between the two image frames and to blend a portion of the first image frame with a portion of the second image frame.

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式