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1. 发明授权

US5945532A Method for manufacture of cephalosporin and intermediates thereof 有权
标题翻译：头孢菌素的制造方法及其中间体
公开(公告)号：US5945532A
公开(公告)日：1999-08-31
申请号：US154787
申请日：1998-09-16
申请人： Debashish Datta , Vinod George , Bishwa Prakash Rai
发明人： Debashish Datta , Vinod George , Bishwa Prakash Rai
IPC分类号： C07D257/04 , C07D277/20 , C07D501/00 , C07D501/34 , C07D501/36
CPC分类号： C07D257/04 , C07D277/587 , C07D501/00
摘要： This invention relates to reactive derivatives of 2-(2-aminothiazol-4-yl)-2-methoxyimino acetic acid and 1H-tetrazol-1-acetic acid of the following general formula I, ##STR1## wherein ##STR2## as well as to use thereof in the manufacture of cephalosporin antibiotics such as cefotaxime, ceftriaxone and cefazolin.
摘要翻译：本发明涉及以下通式I的2-（2-氨基噻唑-4-基）-2-甲氧基亚氨基乙酸和1H-四唑-1-乙酸的活性衍生物，其中以及其在制造中的用途的头孢菌素类抗生素如头孢噻肟，头孢曲松和头孢唑啉。

2. 发明申请

US20110082293A1 PROCESS FOR THE PREPARATION OF STERILE DORIPENEM 失效
标题翻译：制备多西勒多烯的方法
公开(公告)号：US20110082293A1
公开(公告)日：2011-04-07
申请号：US12934348
申请日：2009-03-23
申请人： Vinod George , Hashim Nizar Poovanathil Nagoor Meeran , Neera Tiwari , Mohan Prasad
发明人： Vinod George , Hashim Nizar Poovanathil Nagoor Meeran , Neera Tiwari , Mohan Prasad
IPC分类号： C07D487/04
CPC分类号： C07D477/20
摘要： The present invention relates to a process for the preparation of sterile doripenem.
摘要翻译：本发明涉及无菌多立培南的制备方法。

3. 发明授权

US08445673B2 Process for the preparation of sterile doripenem 失效
标题翻译：无菌多立培南的制备方法
公开(公告)号：US08445673B2
公开(公告)日：2013-05-21
申请号：US12934348
申请日：2009-03-23
申请人： Vinod George , Hashim Nizar Poovanathil Nagoor Meeran , Neera Tiwari , Mohan Prasad
发明人： Vinod George , Hashim Nizar Poovanathil Nagoor Meeran , Neera Tiwari , Mohan Prasad
IPC分类号： C07D477/20
CPC分类号： C07D477/20
摘要： The present invention relates to a process for the preparation of sterile doripenem.
摘要翻译：本发明涉及无菌多立培南的制备方法。

4. 发明申请

US20110172201A1 PROCESS FOR PREPARING A CARBAPENEM ANTIBIOTIC COMPOSITION 审中-公开
标题翻译：制备抗生素组合物的方法
公开(公告)号：US20110172201A1
公开(公告)日：2011-07-14
申请号：US12997668
申请日：2009-06-12
申请人： Vinod George , Bhupendra Vashishta , Mohan Prasad , Naresh Kumar , Vinod Kumar Arora
发明人： Vinod George , Bhupendra Vashishta , Mohan Prasad , Naresh Kumar , Vinod Kumar Arora
IPC分类号： A61K31/407 , C07D477/20 , A61P31/04
CPC分类号： A61K9/0019 , A61K9/19 , A61K31/407 , C07D477/20
摘要： The present invention relates to a process for preparing a carbapenem antibiotic composition. The present invention further relates to a carbapenem antibiotic composition substantially free of degradation impurities. The present invention further relates to a polymorphic form of ertapenem mono sodium designated as Form D and its preparation.
摘要翻译：本发明涉及一种制备碳青霉烯类抗生素组合物的方法。本发明还涉及基本上不含降解杂质的碳青霉烯类抗生素组合物。本发明还涉及被称为D型的ertapenem单钠的多晶形式及其制备方法。

5. 发明授权

US6151567A Data communication analysis and simulation tool 失效
标题翻译：数据通信分析与仿真工具
公开(公告)号：US6151567A
公开(公告)日：2000-11-21
申请号：US250139
申请日：1994-05-27
申请人： Arnold A. Ames , Charles H. Gooden , Donald P. Krakauskas , Vinod George
发明人： Arnold A. Ames , Charles H. Gooden , Donald P. Krakauskas , Vinod George
IPC分类号： H04L12/24 , H04L12/26 , G06F3/00
CPC分类号： H04L41/0806 , H04L41/0846 , H04L41/145 , H04L41/22 , H04L43/14 , H04L43/50 , H04L43/045 , H04L43/0847 , H04L43/0894 , Y04S40/162 , Y04S40/168
摘要： A data communication analysis and simulation tool capable of simulating in real time the transmissions and data responses of at least one line replaceable unit communicating on at least one communication bus with at least one line replaceable unit under test, comprising a computer operating under a real time operating system and having available memory and means for accepting user input, and a programmed simulator resident in said computer comprising a plurality of processes to effectuate the simulation of the transmissions and data responses of at least one line replaceable unit. The programmed simulator allocates a portion of the available memory as a shared memory segment serving as a central database and supporting inter-process communication. The programmed simulator further generates graphical and textural images in response to communicated data from the line replaceable unit under test and user input to a monitor coupled to the computer. The programmed simulator inputs digital and analog inputs and updates the data transmissions in real time, inputs communication data and outputs digital outputs in real time, and maintains data validity and freshness in real time. It allows entry of named engineering unit data to be transmitted and displays received data in engineering units. The simulator is automatically configured for transmission from user defined text file simplifying adaptation. Further, the simulator allows user defined configuration and monitor conditions to be inputed and saved by the user.
摘要翻译：一种数据通信分析和仿真工具，其能够实时模拟至少一个线路可替换单元的传输和数据响应，所述至少一个线路可更换单元在至少一个通信总线上与至少一个可测试线路可替换单元通信，包括实时运行的计算机操作系统并具有用于接受用户输入的可用存储器和装置，以及驻留在所述计算机中的编程模拟器，其包括多个处理以实现对至少一个线路可替换单元的传输和数据响应的模拟。编程的模拟器将可用存储器的一部分分配为用作中央数据库的共享存储器段并且支持进程间通信。编程的模拟器还响应于来自待测线路可更换单元的通信数据和用户输入到耦合到计算机的监视器，生成图形和纹理图像。编程仿真器实时输入数字和模拟输入，更新数据传输，实时输入通信数据和输出数字输出，实时保持数据有效性和新鲜度。允许输入要发送的命名工程单位数据，并以工程单位显示接收到的数据。模拟器自动配置为从用户定义的文本文件传输，从而简化了适配。此外，模拟器允许用户定义的配置和监视条件由用户输入和保存。

6. 发明授权

US5856502A Method for manufacture of cephalosporin and intermediates thereof 失效
标题翻译：头孢菌素的制造方法及其中间体
公开(公告)号：US5856502A
公开(公告)日：1999-01-05
申请号：US995074
申请日：1997-12-19
申请人： Debashish Datta , Vinod George , Bishwa Prakash Rai
发明人： Debashish Datta , Vinod George , Bishwa Prakash Rai
IPC分类号： C07D257/04 , C07D277/20 , C07D501/00 , C07D501/34 , C07D501/36 , C07D277/587
CPC分类号： C07D257/04 , C07D277/587 , C07D501/00
摘要： This invention relates to reactive derivatives of 2-(2-aminothiazol-4-yl)-2-methoxyimino acetic acid and 1H-tetrazol-1-acetic acid of the following general formula I, ##STR1## wherein ##STR2## as well as to use thereof in the manufacture of cephalosporin antibiotics such as cefotaxime, ceftriaxone and cefazolin.
摘要翻译：本发明涉及以下通式I的2-（2-氨基噻唑-4-基）-2-甲氧基亚氨基乙酸和1H-四唑-1-乙酸的反应性衍生物，其中以及其在制造头孢菌素抗生素如头孢噻肟，头孢曲松和头孢唑啉中的用途。

7. 发明授权

US5739346A Dimethyl formiminium chloride chlorosulphate derivatives useful as intermediates for producing cephalosporins 失效
标题翻译：氯化二甲基氯化亚锡盐酸盐衍生物可用作生产头孢菌素的中间体
公开(公告)号：US5739346A
公开(公告)日：1998-04-14
申请号：US624737
申请日：1996-03-26
申请人： Debashish Datta , Vinod George , Bishwa Prakash Rai
发明人： Debashish Datta , Vinod George , Bishwa Prakash Rai
IPC分类号： C07D257/04 , C07D277/20 , C07D501/00 , C07D501/34 , C07D501/36 , C07D277/587
CPC分类号： C07D257/04 , C07D277/587 , C07D501/00
摘要： This invention relates to reactive derivatives of 2-(2-aminothiazol-4-yl)-2-methoxyimino acetic acid and 1H-tetrazol-1-acetic acid of the following general formula I, ##STR1## wherein R.sub.3 = ##STR2## as well as to use thereof in the manufacture of cephalosporin antibiotics such as cefotaxime, ceftriaxone and cefazolin.
摘要翻译：本发明涉及以下通式I的2-（2-氨基噻唑-4-基）-2-甲氧基亚氨基乙酸和1H-四唑-1-乙酸的反应性衍生物，其中R3 = 的头孢菌素类抗生素如头孢噻肟，头孢曲松和头孢唑啉。

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