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1. 发明公开

EP1755870A1 METHOD FOR THE MANUFACTURE OF A FILTER PLATE 审中-公开
标题翻译： VERFAHREN ZUR HERSTELLUNG EINER FILTERPLATTE
公开(公告)号：EP1755870A1
公开(公告)日：2007-02-28
申请号：EP05760358.1
申请日：2005-06-10
申请人： MILLIPORE CORPORATION , Stankowski, Ralph J. , Vigna, James J.
发明人： STANKOWSKI, Ralph , VIGNA, James, J.
IPC分类号： B29C70/76 , B01D25/21 , B29C45/14 , B01D25/12
CPC分类号： B01D63/081 , B01D29/012 , B01D35/30 , B01D63/08 , B01D2313/025 , B29C45/1671 , B29C70/763 , B29L2031/14 , B33Y70/00 , B33Y80/00 , Y10S264/48
摘要： substantially flat polymer, preferably thermoplastic, frame and substantially flat filter material seated fixedly therein. The method is characterized by its reduced exposure of the filter material to adverse mechanical stresses resultant of polymeric frame formation and curing. Toward such end, the substantially flat polymeric frame is formed in at least two separate steps, in the course of which said substantially flat filter material is incorporated. The portion formed first (100) serves as a mechanical restraint, insulating the later incorporated filter material from any propensity of the second 'embedding portion (18) to shrink or otherwise warp during its formation.
摘要翻译：公开了一种用于制造基本平坦的过滤板的方法，该过滤板包括基本上平坦的聚合物该方法的特征在于其过滤材料暴露于聚合物框架形成和固化所产生的不利的机械应力。为此，基本上平坦的聚合物框架以至少两个分开的步骤形成，在该过程中所述基本平坦的过滤材料被结合。首先形成的部分用作机械约束，使后续结合的过滤材料与第二“嵌入”部分的任何倾向绝缘，以在其形成期间收缩或以其它方式翘曲。

2. 发明申请

WO2009151514A1 STIRRED TANK BIOREACTOR 审中-公开
标题翻译：搅拌罐生物反应器
公开(公告)号：WO2009151514A1
公开(公告)日：2009-12-17
申请号：PCT/US2009/002787
申请日：2009-05-06
申请人： MILLIPORE CORPORATION , KELLY, James, E., Jr. , MULDOON, Joseph, William , PROULX, Stephen , VIGNA, James, J.
发明人： KELLY, James, E., Jr. , MULDOON, Joseph, William , PROULX, Stephen , VIGNA, James, J.
IPC分类号： C12M1/10 , C12M1/24
CPC分类号： C12M23/46 , C12M23/20 , C12M23/28 , C12M23/38 , C12M23/48 , C12M27/00 , C12M29/00
摘要： The present invention is a disposable bioreactor formed of molded plastic. The bioreactor (2) is presterilized and has a top (16) and body (22) sealed to each other. One or more ports (30a-c, 32a-c) are formed in the top and side of the housing Preferably at least one port is below the liquid/air level for the housing. The one or more ports that are below the liquid/air interface level may be used as sampling ports or access ports for probes or drains or supply ports for liquids or gases. The bioreactor provides a direct retrofit for the existing glass or steel assembly that utilizes the existing support structures and controls. The molded design overcomes issues of discontinuity, dead spots and the like due to its fixed dimensions that are built in by the molding process. Reproducable probe and other equipment location is also guaranteed through the use of the molded port features. The molded plastic allows for greater flexibility in material selection to reduce or eliminate lipid or cholesterol binding.
摘要翻译：本发明是由模制塑料形成的一次性生物反应器。生物反应器（2）被预灭灭并具有彼此密封的顶部（16）和主体（22）。一个或多个端口（30a-c，32a-c）形成在壳体的顶部和侧部。优选地，至少一个端口在用于壳体的液体/空气水平的下方。低于液体/空气界面水平的一个或多个端口可以用作用于液体或气体的探针或排水口或供应端口的采样端口或访问端口。生物反应器为现有的玻璃或钢组件提供直接改造，利用现有的支撑结构和控制。模制设计克服了由于其通过模制工艺内置的固定尺寸的不连续性，死点等问题。可再生探头等设备的位置也通过使用成型口的特点保证。模制塑料允许在材料选择中更大的灵活性以减少或消除脂质或胆固醇结合。

3. 发明申请

WO2006009638A1 METHOD FOR THE MANUFACTURE OF A FILTER PLATE 审中-公开
标题翻译：过滤板的制造方法
公开(公告)号：WO2006009638A1
公开(公告)日：2006-01-26
申请号：PCT/US2005/020591
申请日：2005-06-10
申请人： MILLIPORE CORPORATION , STANKOWSKI, Ralph , VIGNA, James, J.
发明人： STANKOWSKI, Ralph , VIGNA, James, J.
IPC分类号： B29C70/76
CPC分类号： B01D63/081 , B01D29/012 , B01D35/30 , B01D63/08 , B01D2313/025 , B29C45/1671 , B29C70/763 , B29L2031/14 , B33Y70/00 , B33Y80/00 , Y10S264/48
摘要： substantially flat polymer, preferably thermoplastic, frame and substantially flat filter material seated fixedly therein. The method is characterized by its reduced exposure of the filter material to adverse mechanical stresses resultant of polymeric frame formation and curing. Toward such end, the substantially flat polymeric frame is formed in at least two separate steps, in the course of which said substantially flat filter material is incorporated. The portion formed first (100) serves as a mechanical restraint, insulating the later incorporated filter material from any propensity of the second "embedding portion (18) to shrink or otherwise warp during its formation.
摘要翻译：基本平坦的聚合物，优选热塑性的，框架和固体地固定在其中的基本平坦的过滤材料。该方法的特征在于其过滤材料暴露于聚合物框架形成和固化所产生的不利的机械应力。为此，基本上平坦的聚合物框架形成在至少两个分开的步骤中，其中结合有基本平坦的过滤材料。首先形成的部分（100）用作机械约束，使后续结合的过滤材料与第二“嵌入部分”（18）的任何倾向绝缘，以在其形成期间收缩或以其它方式翘曲。

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