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    • 2. 发明授权
    • Method for the production of esters
    • 酯的制备方法
    • US06720447B1
    • 2004-04-13
    • US09889401
    • 2001-07-17
    • Klaus DitrichUlrich Block
    • Klaus DitrichUlrich Block
    • C07C6966
    • C07C67/08C07C69/708
    • The present invention relates to a novel process for the preparation of esters of the general formula I from compounds of the general formula II contained in aqueous solutions which comprises a) extracting the compounds of the general formula II directly or after liberation from their salts in the presence of a C1-C8-alcohol and a water-immiscible solvent and b) then esterifying with the C1-C8-alcohol in the presence of a catalyst and of an entraining agent under the conditions of an azeotropic distillation, where the process steps (a) and (b) can be carried out separately in terms of time and space or else in a successive continuous or batchwise sequence and where the variables and substituents in the formulae I and II have the following meanings: R1=F, Cl, —OH, —OC1-C10-alkyl, R2=H, C1-C10-alkyl; R3=C1-C8-alkyl, Q=—OH, —O−K+, where K+ is an alkali metal cation or alkaline earth metal cation, n=0, 1 or 2.
    • 本发明涉及制备通式II所示的通式II的化合物的新方法,其中包含在水溶液中的通式II的化合物,它包括:a)直接或者在其存在下直接从其盐中释放出通式II的化合物 C1-C8-醇和一种与水不混溶的溶剂,b)然后在共沸蒸馏条件下,在催化剂和夹带剂的存在下,用C1-C8-醇酯化,其中工艺步骤(a)和( b)可以在时间和空间方面分开进行,或者以连续的或间歇的顺序进行,其中式I和II中的变量和取代基具有以下含义:R 1 = F,Cl,-OH ,-OC 1 -C 10 - 烷基,R 2 = H,C 1 -C 10 - 烷基; R 3 = C 1 -C 8烷基,Q = -OH,-OK 2,其中K < +>是碱金属阳离子或碱土金属阳离子,n = 0,1或2。
    • 3. 发明授权
    • Production of anhydrous or substantially anhydrous formic acid
    • 生产无水或基本无水的甲酸
    • US4326073A
    • 1982-04-20
    • US131501
    • 1980-03-18
    • Dieter WolfRudolf SchmidtUlrich BlockHartmut SchoenmakersKaspar BottGerd Kaibel
    • Dieter WolfRudolf SchmidtUlrich BlockHartmut SchoenmakersKaspar BottGerd Kaibel
    • C07C53/02C07C27/02C07C51/00C07C51/09C07C51/44C07C51/48C07C67/00
    • C07C51/09C07C51/48
    • Anhydrous or substantially anhydrous formic acid is obtained by hydrolysis of methyl formate, in a process wherein(a) methyl formate is hydrolyzed,(b) the methanol and excess methyl formate are distilled from the hydrolysis mixture obtained,(c) the bottom product of distillation (b), consisting of formic acid and water, is extracted, in a liquid-liquid extraction, with an extractant which in the main takes up the formic acid,(d) the resulting extract phase, consisting of formic acid, the extractant and a part of the water, is subjected to distillation,(e) the top product obtained from this distillation and consisting of all or part of the water introduced into the distillation, and part of the formic acid, is recycled, as vapor, into the lower part of the distillation column of stage (b),(f) the bottom product of distillation stage (d), consisting of the extractant, with or without part of the water, and the greater part of the formic acid, is separated by distillation into anhydrous or substantially anhydrous formic acid and the extractant, and(g) the extractant leaving stage (f) is recycled to the process.
    • 在(a)甲酸甲酯水解的过程中,(甲)甲醇和过量的甲酸甲酯从得到的水解混合物中蒸馏得到,(c)甲酸叔丁酯的底部产物 蒸馏(b)由甲酸和水组成,在液 - 液萃取中用主要萃取甲酸的萃取剂萃取,(d)所得提取相由甲酸,萃取剂 和一部分水进行蒸馏,(e)由该蒸馏获得的顶部产物,并且由引入蒸馏的全部或部分水和部分甲酸作为蒸气循环进入 阶段(b)的蒸馏塔的下部,(f)蒸馏阶段(d)的底部产物,由萃取剂组成,有或没有部分水和大部分甲酸分离 通过蒸馏成无水 粗粉或基本上无水的甲酸和萃取剂,和(g)离开阶段(f)的萃取剂再循环到该方法中。