专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

US20180258511A1 Process for the production of metallic gold nanoparticles from na efluente arising from acid mine drainage bioremediation 审中-公开
公开(公告)号：US20180258511A1
公开(公告)日：2018-09-13
申请号：US15764415
申请日：2015-09-30
申请人： Universidade do Algarve , Centro de Ciências do Mar - CCMAR
发明人： Maria Clara Silva Costa , Ana Filipa Benedito Assunção
IPC分类号： C22B3/00 , B22F9/24
CPC分类号： C22B11/042 , B22F1/0018 , B22F9/24 , B22F2301/255 , C22B7/00 , C22B7/006 , C22B11/04 , Y02P10/238
摘要： The present request describes a process to obtain metallic gold nanoparticles from an effluent containing sulfide, resulting from a bioremediation process of acid mine drainage (AMD) based on the use of sulfate-reducing bacteria. The disclosed process consists of the effluent addition to a gold solution in concentrations between 20-250 mg/L, in batch or continuous systems, allowing to obtain nanoparticles of Au(0) with a yield of 70-100%.

2. 发明公开

US20240045441A1 COMPUTER IMPLEMENTED METHOD FOR THE INDEXING OF TWO DIMENSIONAL SPACES, ROBOT LOCATION SYSTEM, COMPUTER PROGRAM, AND COMPUTER-READABLE DATA CARRIER THEREOF 审中-公开
公开(公告)号：US20240045441A1
公开(公告)日：2024-02-08
申请号：US18266780
申请日：2021-12-09
申请人： UNIVERSIDADE DO ALGARVE
发明人： Jânio Miguel EVANGELISTA FERREIRA MONTEIRO , André DA SILVA PEDRO , António João FREITAS GOMES DA SILVA
IPC分类号： G05D1/02
CPC分类号： G05D1/0274 , G05D1/027 , G05D1/0246
摘要： The invention comprises a computer implemented method for the indexing of one and two-dimensional spaces using Gray code sequences, wherein the said method comprises a spatial indexing based in a triangular coordinate system, wherein the triangles are subdivided forming a plurality of sub-triangles, which are further encoded, resulting in a plurality of encoded layers; and a generation of a hexagonal coordinate system, which can be used to define the location of an autonomous robot.
The invention meets the requirements for the spatial encoding, since it allows that two adjacent locations have a high degree of similarity, it is immune to transition errors when moving between adjacent locations, and allows the logical aggregation of neighbor locations to enable the spatial indexing of assets and objects that might span over several spatial units.

3. 发明申请

US20220404845A1 PRESSURE STABILIZER 有权
公开(公告)号：US20220404845A1
公开(公告)日：2022-12-22
申请号：US17774131
申请日：2020-11-04
申请人： UNIVERSIDADE DE COIMBRA , UNIVERSIDADE DO ALGARVE
发明人： João Luís MENDES PEDROSO DE LIMA , Jorge Manuel GUIEIRO PEREIRA ISIDORO
IPC分类号： G05D16/04 , F16K17/18
摘要： The present invention relates to a pressure stabilizer (14) comprising a constant pressure chamber (10) to which 3 pipes are attached, namely an outlet pipe (13), located downstream of the pressure stabilizer (14), an inlet pipe (11) and a return pipe (12), both placed upstream of the pressure stabilizer (14). The pressure stabilizer (14) prevents hydraulic shocks, which can potentially damage hydraulic installations. The devices described in the state of the art do not allow to stabilize efficiently spiky pressure fluctuations by means of simple hydraulic systems. The present invention by means of the combined operation of a pressure reducing valve (2) and a relief valve (3), will eliminate the pressure peaks at the inlet of hydraulic installations.

4. 发明公开

US20240068046A1 METHODS OF ANALYSIS OF ALLELIC EXPRESSION OF PIK3CA IN CANCER AND USES THEREOF 审中-公开
公开(公告)号：US20240068046A1
公开(公告)日：2024-02-29
申请号：US18460549
申请日：2023-09-03
申请人： UNIVERSIDADE DO ALGARVE
发明人： Ana Teresa LUÍS LOPES MAIA , Joana GONÇALVES DE GOUVEIA MAIA XAVIER , Lizelle WINKELSTRÖTER CORREIA , Ramiro Emanuel MAGNO MORGADO
IPC分类号： C12Q1/6886
CPC分类号： C12Q1/6886 , C12Q2600/158 , C12Q2600/156 , C12Q2600/118 , C12Q2600/106
摘要： The invention provides a method of identifying a subset of cancer patients with a poor prognosis, comprising comparing the allelic expression of a mutant and wildtype PIK3CA allele in a patient sample. The invention further teaches the use of drugs targeting the mutant PI3K protein in a subset of patients which are determined to express the a mutant PIK3CA allele above a certain threshold, in addition to a kit, or system with which PIK3CA allelic expression may be assessed.

5. 发明公开

US20240336979A1 METHODS OF ANALYSIS OF 17Q22 POLYMORPHISMS ASSOCIATED WITH CANCER AND USES THEREOF 审中-公开
公开(公告)号：US20240336979A1
公开(公告)日：2024-10-10
申请号：US18735246
申请日：2024-06-06
申请人： UNIVERSIDADE DO ALGARVE
发明人： Joana GONÇALVES DE GOUVEIA MAIA XAVIER , Ana Teresa LUÍS LOPES MAIA , Filipa Alexandra OLEIRO ESTEVES RIBEIROS
IPC分类号： C12Q1/6886 , C12Q1/6851
CPC分类号： C12Q1/6886 , C12Q1/6851 , C12Q2600/106 , C12Q2600/156 , C12Q2600/158
摘要： The invention relates to a method of predicting a subject's likelihood of being diagnosed with a malignant cancer, comprising measuring the relative expression level of a reference allele and an alternative allele of selected cancer risk associated polymorphisms in 17q22 in blood samples.

6. 发明公开

US20240238385A1 ISOLATED OR ARTIFICIAL NUCLEOTIDE SEQUENCES FOR USE IN NEURODEGENERATIVE DISEASES 审中-公开
公开(公告)号：US20240238385A1
公开(公告)日：2024-07-18
申请号：US18559936
申请日：2022-05-13
申请人： Universidade do Algarve
发明人： Clévio David RODRIGUES NÓBREGA , Rebekah COVACO KOPPENOL , Adriana Isabel DO VALE MARCELO , André Filipe VIEIRA DA CONCEIÇÃO
IPC分类号： A61K38/46 , A61K48/00
CPC分类号： A61K38/46 , A61K48/0033 , A61K48/005
摘要： The present disclosure relates to an isolated or artificial nucleotide sequence encoding the GTPase-activating protein-binding protein 1 (G3BP1), for use in medicine, preferably in the treatment of polyglutamine diseases. Furthermore, the present invention is also related to a vector comprising such sequence, a host cell comprising such vector, a protein G3BP1, or a composition thereof, for use for use in medicine, preferably in the treatment of polyglutamine diseases.

7. 发明申请

WO2010024704A4 A GAMMACARBOXYGLUTAMATE-RICH PROTEIN, METHODS AND ASSAYS FOR ITS DETECTION, PURIFICATION AND QUANTIFICATION AND USES THEREOF 审中-公开
公开(公告)号：WO2010024704A4
公开(公告)日：2010-03-04
申请号：PCT/PT2009/000046
申请日：2009-08-27
申请人： UNIVERSIDADE DO ALGARVE , FERNANDES RODRIGUES DA COSTA SIMES, Dina Cristina , SÃO BENTO VIEGAS, Carla Alexandra , QUINTAIS CANCELA DA FONSECA, Maria Leonor
发明人： FERNANDES RODRIGUES DA COSTA SIMES, Dina Cristina , SÃO BENTO VIEGAS, Carla Alexandra , QUINTAIS CANCELA DA FONSECA, Maria Leonor
IPC分类号： C07K14/46 , C07K14/78 , C07K16/18 , G01N33/50 , G01N33/53
摘要： The present invention refers to a gammacarboxyglutamate -rich protein that shows in vivo a high capacity to bind calcium through specific gamma carboxylated glutamic acid residues (Gla). It includes a description of the referred protein, purification procedures, protein detection and quantification tools and methods.. This invention also refers to a kit for the detection and quantification of said protein in samples. This kit includes the use of one or more antibodies produced against the homologous sequence of the target species to be analyzed, and thus, methods for the production of such antibodies are disclosed as well. In another aspect of the invention, the methods and tools described hereby are used as biomarkers for evaluation of presence or risk to develop certain diseases. In another aspect of this invention, available complete GRP cDNA and gene sequences obtained from several species also enable the in vitro production of antigens, the quantification of GRP expression, the screening of GRP polymorphisms to access the predisposition for certain diseases and the screening for GRP mutations.

8. 发明公开

EP4055461A1 PRESSURE STABILIZER 无效
公开(公告)号：EP4055461A1
公开(公告)日：2022-09-14
申请号：EP20833982.0
申请日：2020-11-04
申请人： Universidade de Coimbra , Universidade Do Algarve
发明人： MENDES PEDROSO DE LIMA, João Luís , GUIEIRO PEREIRA ISIDORO, Jorge Manuel
IPC分类号： G05D16/04 , B05B12/08

9. 发明公开

EP2326664A2 A GAMMACARBOXYGLUTAMATE-RICH PROTEIN, METHODS AND ASSAYS FOR ITS DETECTION, PURIFICATION AND QUANTIFICATION AND USES THEREOF 审中-公开
标题翻译： FOR ITS，其纯化及其量化AND A GAMMACARBOXYGLUTAMATREICHES蛋白质，方法和检测方法及其用途
公开(公告)号：EP2326664A2
公开(公告)日：2011-06-01
申请号：EP09737193.4
申请日：2009-08-27
申请人： Universidade Do Algarve
发明人： FERNANDES RODRIGUES DA COSTA SIMES, Dina Cristina , SÃO BENTO VIEGAS, Carla Alexandra , QUINTAIS CANCELA DA FONSECA, Maria Leonor
IPC分类号： C07K14/435
CPC分类号： C07K14/461 , C07K14/46 , C07K14/78 , C07K16/18 , G01N33/68 , G01N33/6893
摘要： The present invention refers to a gammacarboxyglutamate -rich protein that shows in vivo a high capacity to bind calcium through specific gamma carboxylated glutamic acid residues (Gla). It includes a description of the referred protein, purification procedures, protein detection and quantification tools and methods.. This invention also refers to a kit for the detection and quantification of said protein in samples. This kit includes the use of one or more antibodies produced against the homologous sequence of the target species to be analyzed, and thus, methods for the production of such antibodies are disclosed as well. In another aspect of the invention, the methods and tools described hereby are used as biomarkers for evaluation of presence or risk to develop certain diseases. In another aspect of this invention, available complete GRP cDNA and gene sequences obtained from several species also enable the in vitro production of antigens, the quantification of GRP expression, the screening of GRP polymorphisms to access the predisposition for certain diseases and the screening for GRP mutations.
摘要翻译：当前盘游离缺失的主题是指富gammacarboxyglutamate蛋白确实显示了在体内通过特定的γ羧化谷氨酸残基（GLA）结合钙的高容量。它包括由蛋白质，纯化方法，蛋白检测和定量的工具和方法的称为的描述。一种用于所述蛋白质的样品中检测和定量试剂盒是预期的。该试剂盒可以包括使用对目标物种的同源序列产生的一种或多种抗体被分析，并且因此，用于生产检测抗体的方法是游离缺失盘以及。在另一个方面中，所述方法和在此所描述的工具可以被用作生物标志物的存在或风险评估开发某些疾病。在游离缺失的主题的光盘的另一个方面中，从几个物种中获得可用的完整GRP cDNA和基因序列从而能够在体外生产抗原，GRP表达的定量，GRP多态性的筛选以访问某些疾病和筛选易感性 GRP的突变。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式