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1. 发明专利

JPH08104697A TIN DERIVATIVE AT ANOMERIC POSITION OF SUGAR 失效
公开(公告)号：JPH08104697A
公开(公告)日：1996-04-23
申请号：JP20908095
申请日：1995-07-25
申请人： UNIV BAR ILAN , YEDA RES & DEV
发明人： EIBURAHAMU NUDERUMAN , YAAKOBU HERUJIGU , EFUDO KEINAN
IPC分类号： C07H13/06 , C07F7/22 , C07H1/00 , C07H13/10 , C07H15/04 , C07H23/00

2. 发明专利

JPH02258723A COMPOSITION AND METHOD FOR IDUCING GENERATION OF CYTOKINE 失效
公开(公告)号：JPH02258723A
公开(公告)日：1990-10-19
申请号：JP1596290
申请日：1990-01-25
申请人： UNIV BAR ILAN
发明人： BENJIYAMIN SUREDONI , MAIKERU ARUBETSUKU
IPC分类号： A61K33/04 , A61K33/16 , A61K33/18 , A61P31/12 , A61P35/00 , A61P37/00 , C07C395/00
摘要： PURPOSE: To obtain a composition for inducing cytokine formation by compounding a tellurium tetrahalide as an active component. CONSTITUTION: This pharmaceutical composition is composed of a tellurium tetrahalide and a pharmaceutically permissible support. The treatment of cancer, immunodeficiency, an autoimmune disease or an infectious disease is performed by using a tellurium tetrahalide as a supplemental agent or a primary treating agent. The composition stimulates cytokine formation in a living body. Further, the dose of the compound for treating said disease is 0.01-1 mg/kg-body weight, preferably 0.02-0.5mg/kg-body weight, and in the case of in vitro use, the compound in the range of 1×10 to 1×10 g, preferably 1×10 to 1×10 g is used for 10 cells/ml.

3. 发明专利

JPH0242056A COMPOSITE OF TELLULIUM AND SELENIUM DERIVATIVES 失效
公开(公告)号：JPH0242056A
公开(公告)日：1990-02-13
申请号：JP6341789
申请日：1989-03-14
申请人： UNIV BAR ILAN
发明人： BENJIYAMIN SUREDONII , MAIKERU ARUBETSUKU , REO PABURIFU
IPC分类号： A61K31/095 , A61K20060101 , A61K31/04 , A61K31/065 , A61K31/33 , A61K31/66 , A61K33/04 , A61P17/00 , A61P31/04 , A61P35/00 , A61P37/00 , C07C391/00 , C07C395/00 , C07D329/00 , C07F20060101 , C07F9/54 , C07F15/00

4. 发明专利

JP2011140505A Method and pharmaceutical composition for healing wound 有权
标题翻译：治疗方法和药物组合物
公开(公告)号：JP2011140505A
公开(公告)日：2011-07-21
申请号：JP2011046656
申请日：2011-03-03
申请人： Univ Bar Ilan , バル・イラン・ユニバーシティBar Ilan University
发明人： TENNENBAUM TAMAR , SAMPSON SANFORD , KUROKI TOSHIO , ALT ADDY , SHEN SHLOMZION
IPC分类号： A61K38/28 , C12N15/09 , A61K31/7088 , A61K35/12 , A61K35/36 , A61K38/45 , A61K45/00 , A61K48/00 , A61P3/10 , A61P17/02 , A61P43/00 , C12N5/071 , C12N5/10 , C12N9/12 , C12N15/54
CPC分类号： C12N5/0629 , A61K35/12 , A61K38/28 , A61K38/45 , C12N9/1205 , C12N2501/33 , C12N2501/70 , C12N2510/00 , C12N2799/022
摘要： PROBLEM TO BE SOLVED: To provide a pharmaceutical composition for inducing or accelerating a healing process of a wound by inducing and/or accelerating cell proliferation and/or cell differentiation.
SOLUTION: There is provided a method for inducing or accelerating the healing process of skin wound comprising a step to administer a therapeutically active amount of insulin to the skin wound for inducing or accelerating the healing process of the skin wound.
COPYRIGHT: (C)2011,JPO&INPIT
摘要翻译：待解决的问题：提供通过诱导和/或促进细胞增殖和/或细胞分化来诱导或加速伤口愈合过程的药物组合物。提供了诱导或加速皮肤伤口愈合过程的方法，包括向皮肤伤口施用治疗活性量的胰岛素以诱导或加速皮肤伤口愈合过程的步骤。版权所有（C）2011，JPO＆INPIT

5. 发明专利

JPH10152436A MEDICINAL COMPOSITION CONTAINING BIOLOGICALLY ACTIVE CARBOXYLIC ACID ESTERS 失效
公开(公告)号：JPH10152436A
公开(公告)日：1998-06-09
申请号：JP31537197
申请日：1997-11-17
申请人： UNIV BAR ILAN , KUPAT HOLIM HEALTH INSURANCE
发明人： NUDELMAN ABRAHAM , SHAKLAI MATITIAHU , REPHAELI ADA
IPC分类号： C07C271/16 , A61K31/215 , A61K31/22 , A61K31/225 , A61K31/335 , A61K31/357 , A61P35/00 , A61P37/00 , A61P37/02 , A61P37/04 , C07C67/00 , C07C69/003 , C07C69/28 , C07C69/96 , C07C227/00 , C07C227/16 , C07C227/18 , C07C229/08 , C07C229/36 , C07C239/00 , C07D307/83 , C07D307/89 , C07D317/34 , C07D317/40
摘要： PROBLEM TO BE SOLVED: To obtain the subject composition which is active in a low concentration and useful as an antitumor agent and for treatment of immunodeficiency by including a biologically active specific carboxylic acid ester and a carrier, etc. SOLUTION: This medicinal composition is obtained by including at least one compound represented by the formula CH3 -CH2 CH2 -C(=O)-O-CHR-O-(O=)C- R' (R is H or an alkyl; R' is an alkyl except when R is H and R' is tertiary butyl) and an adjuvant, a diluent or a carrier. The composition is extremely effective and low in toxicity to hosts.

6. 发明专利

JPH0276817A ANTI-ALLERGIC EXTRACT 失效
公开(公告)号：JPH0276817A
公开(公告)日：1990-03-16
申请号：JP11619989
申请日：1989-05-11
申请人： UNIV BAR ILAN
发明人： SHIROMO GUROSUMAN , RINA RETSUNIKU , DEBITSUDO ARUTOMAN
IPC分类号： A61K36/00 , A61K20060101 , A61K9/22 , A61K9/52 , A61K36/18 , A61K36/185 , A61P17/00 , A61P29/00 , A61P37/08 , C07G99/00 , C12N9/04
摘要： PURPOSE: To obtain a medicinal composition containing an aqueous extract from a plant belonging to the order of Malvales and useful for the treatment of rheumatic and psoriasis. CONSTITUTION: This water soluble antiallergic extract capable of inhibiting the formation of at least one kind selected from the group consisting of a histamine and a leucotriene in a living body, is obtained by finely crushing a plant selected from plants belonging to the order of Malvales, preferably family of Malvaceae, especially the genus of Malva, Althaeae and Lavatera, then extracting the plant by using water in an amount of the plant to water ratio of (5:100)-(1.0:0.5) range at a temperature of 4-100 deg.C. The extract is subject to a chromatography, and a fraction having a high activity evaluated as to the antiallergic activity, is separated. The active component is used as preparations such as a solution, a syrup, an injectable material, tablets, capsules and cream, and in the case of a form for an internal use, the active component is contained in an amount of giving 20-500mg/kg active component.

7. 发明专利

JPS61215386A CYTOKINE PRODUCTION STIMULATING COMPOUND 失效
公开(公告)号：JPS61215386A
公开(公告)日：1986-09-25
申请号：JP25097785
申请日：1985-11-11
申请人： UNIV BAR ILAN
发明人： MAIKERU ARUBETSUKU , BENJIYAMIN SUREDONI
IPC分类号： A61K9/08 , A61K31/047 , A61K31/095 , A61K31/28 , A61K31/33 , A61K31/555 , A61K31/66 , A61K31/665 , A61K33/04 , A61K33/24 , A61P31/12 , A61P35/00 , A61P37/00 , A61P43/00 , C01B19/00 , C07C395/00 , C07D329/00 , C07D517/10

8. 发明专利

JPH10152454A BIOLOGICALLY ACTIVE CARBOXYLIC ACID ESTERS 失效
公开(公告)号：JPH10152454A
公开(公告)日：1998-06-09
申请号：JP31537497
申请日：1997-11-17
申请人： UNIV BAR ILAN , KUPAT HOLIM HEALTH INSURANCE
发明人： NUDELMAN ABRAHAM , SHAKLAI MATITIAHU , REPHAELI ADA
IPC分类号： C07C271/16 , A61K31/215 , A61K31/22 , A61K31/225 , A61K31/335 , A61K31/357 , A61P35/00 , A61P37/00 , A61P37/02 , A61P37/04 , C07C67/00 , C07C69/003 , C07C69/28 , C07C69/96 , C07C227/00 , C07C227/16 , C07C227/18 , C07C229/08 , C07C229/36 , C07C239/00 , C07D307/83 , C07D307/89 , C07D317/34 , C07D317/40
摘要： PROBLEM TO BE SOLVED: To obtain the subject new compound useful as a medicine for suppressing proliferation of malignant tumor and stimulating differentiation of malignant cell. SOLUTION: This compound is shown by the formula CH3 -CH2 -CH2 -C(=0)-0- CHR-O(O=C)C-R' (R is H or an alkyl; R' is an alkoxy) such as pivaloyloxymethyl butyrate. The compound of the formula is produced by reacting butyric acid with a reagent of the formula Y-CHR-0-(0=)C-R' (Y is an eliminable group such as a halogen or methanesulfonate) in the presence of a base. For example, a trialkylamine or an alkali metal carbonate is used as the base.

9. 发明专利

JPH07330803A BIOLOGICALLY ACTIVE CONJUGATE OF CELLULOSE WITH AMINO COMPOUND 失效
公开(公告)号：JPH07330803A
公开(公告)日：1995-12-19
申请号：JP5436794
申请日：1994-02-15
申请人： UNIV BAR ILAN
发明人： SHIYUROMO MAAGERU , SOFUAA SUTOUUCHIYATSUKU
IPC分类号： A61K38/00 , A61K38/46 , A61K45/00 , A61K47/48 , A61L15/40 , A61L15/44 , A61L26/00 , A61P43/00 , C08B15/06 , C08B37/00

10. 发明专利

JPH05250499A 失效
公开(公告)号：JPH05250499A
公开(公告)日：1993-09-28
申请号：JP85093
申请日：1993-01-06
申请人： UNIV BAR ILAN
发明人： ISURAERU GOTSUTORIIBU , IEEDA SHINGAA
IPC分类号： G06F15/82 , G06F9/38 , G06F9/44 , G06F11/34
摘要： PURPOSE: To provide a data flow machine with which a critical path is executed in a minimum time by executing a path process depending on data. CONSTITUTION: A device is provided for filling an instruction queue 110 with plural instructions and one correspondent external operand 124 at least and according to plural data depending path processes, further, the instructions are successively applied to a device for instructing which data depending path process the instruction belongs to, one external operand 124 at least for respective instructions in the instruction queue 110, and active operand corresponding to the data depending path process to which the instruction belongs. At the same time, this machine is provided with an executing device 100 for generating the result from the respective instructions and a means for storing the result as the active operand so as to use it through an executing means corresponding to the next instruction of the data depending path process.

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