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1. 发明申请

US20110198742A1 SEMICONDUCTOR DEVICE AND ELECTRONIC DEVICE 有权
标题翻译：半导体器件和电子器件
公开(公告)号：US20110198742A1
公开(公告)日：2011-08-18
申请号：US13094383
申请日：2011-04-26
申请人： Tadatoshi Danno , Tsutomu Tsuchiya
发明人： Tadatoshi Danno , Tsutomu Tsuchiya
IPC分类号： H01L23/495
CPC分类号： H01L24/32 , H01L21/561 , H01L23/3107 , H01L23/49503 , H01L23/49548 , H01L23/50 , H01L23/66 , H01L24/45 , H01L24/48 , H01L24/49 , H01L24/73 , H01L24/85 , H01L24/97 , H01L2223/6611 , H01L2224/05554 , H01L2224/27013 , H01L2224/29007 , H01L2224/32013 , H01L2224/32014 , H01L2224/32245 , H01L2224/45015 , H01L2224/45144 , H01L2224/48011 , H01L2224/48091 , H01L2224/48095 , H01L2224/48247 , H01L2224/48253 , H01L2224/48257 , H01L2224/484 , H01L2224/48599 , H01L2224/4911 , H01L2224/49171 , H01L2224/73265 , H01L2224/85 , H01L2224/92 , H01L2224/92247 , H01L2224/97 , H01L2924/00014 , H01L2924/01005 , H01L2924/01006 , H01L2924/01013 , H01L2924/01014 , H01L2924/01015 , H01L2924/01019 , H01L2924/01023 , H01L2924/01029 , H01L2924/01033 , H01L2924/01039 , H01L2924/01046 , H01L2924/01047 , H01L2924/01078 , H01L2924/01079 , H01L2924/01082 , H01L2924/01087 , H01L2924/014 , H01L2924/10162 , H01L2924/10253 , H01L2924/12036 , H01L2924/1306 , H01L2924/13091 , H01L2924/14 , H01L2924/15747 , H01L2924/181 , H01L2924/19041 , H01L2924/19043 , H01L2924/19107 , H01L2924/20752 , H01L2924/30105 , H01L2924/30107 , H01L2924/3011 , H01L2924/3025 , H01L2924/351 , H03F3/189 , H01L2924/20645 , H01L2224/83 , H01L2224/78 , H01L2924/00012 , H01L2924/00 , H01L2224/85399 , H01L2224/05599
摘要： This invention provides a high frequency power module which is incorporated into a mobile phone and which incorporates high frequency portion analogue signal processing ICs including low noise amplifiers which amplify an extremely weak signal therein. A semiconductor device includes a sealing body which is made of insulation resin, a plurality of leads which are provided inside and outside the sealing body, a tab which is provided inside the sealing body and has a semiconductor element fixing region and a wire connection region on a main surface thereof, a semiconductor element which is fixed to the semiconductor element fixing region and includes electrode terminals on an exposed main surface, conductive wires which connect electrode terminals of the semiconductor element and the leads, and conductive wires which connect electrode terminals of the semiconductor element and the wire connecting region of the tab. In such a semiconductor device, a circuit formed in the semiconductor element in a monolithic manner is comprised of a plurality of circuit parts and, in a specified circuit part (a low noise amplifier) which forms a portion of the circuit parts, all grounding electrode terminals out of electrode terminals of the semiconductor element are not connected to the tab through wires but are connected with the leads through wires.
摘要翻译：本发明提供一种并入移动电话中的高频功率模块，其包括高频部分模拟信号处理IC，包括放大其中极弱信号的低噪声放大器。一种半导体器件，包括由绝缘树脂制成的密封体，设置在密封体的内部和外部的多个引线，设置在密封体内部并具有半导体元件固定区域和导线连接区域的突片其主表面，固定到半导体元件固定区并且在暴露的主表面上包括电极端子的半导体元件，连接半导体元件的电极端子和引线的导线以及连接半导体元件的电极端子的导线半导体元件和引线连接区域。在这种半导体装置中，以单片方式形成在半导体元件中的电路由多个电路部分构成，并且在形成电路部分的一部分的规定电路部分（低噪声放大器）中，所有接地极半导体元件的电极端子之外的端子不通过导线连接到突片，而是通过导线与引线连接。

2. 发明申请

US20080146187A1 SEMICONDUCTOR DEVICE AND ELECTRONIC DEVICE 有权
标题翻译：半导体器件和电子器件
公开(公告)号：US20080146187A1
公开(公告)日：2008-06-19
申请号：US12032690
申请日：2008-02-17
申请人： Tadatoshi DANNO , Tsutomu Tsuchiya
发明人： Tadatoshi DANNO , Tsutomu Tsuchiya
IPC分类号： H04B1/28
CPC分类号： H01L24/32 , H01L21/561 , H01L23/3107 , H01L23/49503 , H01L23/49548 , H01L23/50 , H01L23/66 , H01L24/45 , H01L24/48 , H01L24/49 , H01L24/73 , H01L24/85 , H01L24/97 , H01L2223/6611 , H01L2224/05554 , H01L2224/27013 , H01L2224/29007 , H01L2224/32013 , H01L2224/32014 , H01L2224/32245 , H01L2224/45015 , H01L2224/45144 , H01L2224/48011 , H01L2224/48091 , H01L2224/48095 , H01L2224/48247 , H01L2224/48253 , H01L2224/48257 , H01L2224/484 , H01L2224/48599 , H01L2224/4911 , H01L2224/49171 , H01L2224/73265 , H01L2224/85 , H01L2224/92 , H01L2224/92247 , H01L2224/97 , H01L2924/00014 , H01L2924/01005 , H01L2924/01006 , H01L2924/01013 , H01L2924/01014 , H01L2924/01015 , H01L2924/01019 , H01L2924/01023 , H01L2924/01029 , H01L2924/01033 , H01L2924/01039 , H01L2924/01046 , H01L2924/01047 , H01L2924/01078 , H01L2924/01079 , H01L2924/01082 , H01L2924/01087 , H01L2924/014 , H01L2924/10162 , H01L2924/10253 , H01L2924/12036 , H01L2924/1306 , H01L2924/13091 , H01L2924/14 , H01L2924/15747 , H01L2924/181 , H01L2924/19041 , H01L2924/19043 , H01L2924/19107 , H01L2924/20752 , H01L2924/30105 , H01L2924/30107 , H01L2924/3011 , H01L2924/3025 , H01L2924/351 , H03F3/189 , H01L2924/20645 , H01L2224/83 , H01L2224/78 , H01L2924/00012 , H01L2924/00 , H01L2224/85399 , H01L2224/05599
摘要： This invention provides a high frequency power module which is incorporated into a mobile phone and which incorporates high frequency portion analogue signal processing ICs including low noise amplifiers which amplify an extremely weak signal therein. A semiconductor device includes a sealing body which is made of insulation resin, a plurality of leads which are provided inside and outside the sealing body, a tab which is provided inside the sealing body and has a semiconductor element fixing region and a wire connection region on a main surface thereof, a semiconductor element which is fixed to the semiconductor element fixing region and includes electrode terminals on an exposed main surface, conductive wires which connect electrode terminals of the semiconductor element and the leads, and conductive wires which connect electrode terminals of the semiconductor element and the wire connecting region of the tab. In such a semiconductor device, a circuit formed in the semiconductor element in a monolithic manner is comprised of a plurality of circuit parts and, in a specified circuit part (a low noise amplifier) which forms a portion of the circuit parts, all grounding electrode terminals out of electrode terminals of the semiconductor element are not connected to the tab through wires but are connected with the leads through wires.
摘要翻译：本发明提供一种并入移动电话中的高频功率模块，其包括高频部分模拟信号处理IC，包括放大其中极弱信号的低噪声放大器。一种半导体器件，包括由绝缘树脂制成的密封体，设置在密封体的内部和外部的多个引线，设置在密封体内部并具有半导体元件固定区域和导线连接区域的突片其主表面，固定到半导体元件固定区并且在暴露的主表面上包括电极端子的半导体元件，连接半导体元件的电极端子和引线的导线以及连接半导体元件的电极端子的导线半导体元件和引线连接区域。在这种半导体装置中，以单片方式形成在半导体元件中的电路由多个电路部分构成，并且在形成电路部分的一部分的规定电路部分（低噪声放大器）中，所有接地极半导体元件的电极端子之外的端子不通过导线连接到突片，而是通过导线与引线连接。

3. 外观设计

USD516600S1 Video camera 有权
公开(公告)号：USD516600S1
公开(公告)日：2006-03-07
申请号：US29216211
申请日：2004-10-29
申请人： Tsutomu Tsuchiya
设计人： Tsutomu Tsuchiya

4. 发明授权

US6075135A 3,4-di-O,N-Protected-4-amino-2,4,6-trideoxy-2-fluoro-L-manno-pyranosyl halide and a process for its preparation 失效
标题翻译： 3,4-二-O，N-保护的-4-氨基-2,4,6-三脱氧-2-氟-L-壬烷 - 吡喃糖基卤化物及其制备方法
公开(公告)号：US6075135A
公开(公告)日：2000-06-13
申请号：US282200
申请日：1999-03-31
申请人： Tomio Takeuchi , Sumio Umezawa , Tsutomu Tsuchiya , Yasushi Takagi
发明人： Tomio Takeuchi , Sumio Umezawa , Tsutomu Tsuchiya , Yasushi Takagi
IPC分类号： A61K31/70 , A61K31/7028 , A61K31/7034 , A61K31/704 , A61P35/00 , C07H15/244 , C07H15/252 , C07H1/00 , C07H5/00
CPC分类号： C07H15/252 , C07H15/244 , Y02P20/55
摘要： 7-O-(4-Amino-2,4,6-trideoxy-2-fluoro-.alpha.-L-mannopyranosyl)-daunomycinone or -adriamycinone is now synthesized as a daunomycinone or adriamycinone derivative having the general formula ##STR1## wherein R is a hydrogen atom or hydroxyl group. These novel compounds according to this invention exhibit excellent antitumor activities and have a high solubility in water, and hence they are useful as an antitumor agent.
摘要翻译：现在，合成7-O-（4-氨基-2,4,6-三脱氧-2-氟-α-L-吡喃甘露糖基） - 日诺霉素酮或阿曲达霉素，作为具有通式的道诺霉素酮或阿霉素酮衍生物，其中R是氢原子或羟基。根据本发明的这些新化合物表现出优异的抗肿瘤活性，并且在水中的溶解度高，因此它们可用作抗肿瘤剂。

5. 发明授权

US5789386A Fluorine-containing anthracycline derivatives having hydroxyl groups(s) mono- or di-o-aminoalkanoylated in the sugar moiety thereof 失效
标题翻译：在其糖部分中具有单或二氨基烷氧基的羟基的含氟蒽环类衍生物
公开(公告)号：US5789386A
公开(公告)日：1998-08-04
申请号：US709297
申请日：1996-09-09
申请人： Tomio Takeuchi , Sumio Umezawa , Tsutomu Tsuchiya , Yasushi Takagi , Hiromi Sohtome
发明人： Tomio Takeuchi , Sumio Umezawa , Tsutomu Tsuchiya , Yasushi Takagi , Hiromi Sohtome
IPC分类号： C07H15/252 , A61K31/70 , C07H15/24
CPC分类号： C07H15/252
摘要： To provide novel fluorine-containing anthracycline derivatives having high antitumor activities and a solubility in water, there have now been synthesized a 7-O-(2,6-dideoxy-2-fluoro-3-O- or -4-O- or -3,4-di-O-aminoalkanoyl-.alpha.-L-talopyranosyl)daunomycinone or -adriamycinone of general formula (I) shown below, as well as a 7-O-(3-O- or -4-O- or -3,4-di-O-aminoalkanoyl-2,6-dideoxy-2,6,6,6-tetrafluoro-.alpha.-L-talopyranosyl- or -2,6-dideoxy-6,6,6-trifluoro-.alpha.-L-lyxo-hexopyranosyl)adriamycinone of general formula (II) shown below: General formula (I) ##STR1## General formula (II) ##STR2## wherein either one or both of A.sup.1 and A.sup.2 is or are an .alpha.-amino acid residue or an .omega.-amino acid residue and T denotes a fluorine or hydrogen atom. The novel fluorine-containing anthracycline derivatives of general formulae (I) and (II) are highly active against tumors and soluble in water, and they are useful as antitumor agents administrable in the form of injectable solution.
摘要翻译：为了提供具有高抗肿瘤活性和在水中的溶解性的新型含氟蒽环类衍生物，现在已经合成了7-O-（2,6-二脱氧-2-氟-3-O-或-4-O-或 -3,4-二-O-氨基链烷酰-α-L-吡喃葡萄糖基）道诺霉素酮或下列通式（I）的阿霉素酮，以及7-O-（3-O-或-4-O-或 -3,4-二-O-氨基链烷酰基-2,6-二脱氧-2,6,6,6-四氟-α-L-吡喃木糖基或-2,6-二脱氧-6,6,6-三氟-α （II）的通式（Ⅰ）所示的通式（Ⅰ）所示的通式（Ⅰ）的L-赖氨酸 - 六吡喃糖基）的阿霉素酮：通式（Ⅰ）是α-氨基酸残基或ω-氨基酸残基，T表示氟或氢原子。通式（I）和（II）的新型含氟蒽环类衍生物对肿瘤具有高度活性并且可溶于水，并且它们可用作以可注射溶液形式施用的抗肿瘤剂。

6. 外观设计

USD384940S Remote controller 失效
公开(公告)号：USD384940S
公开(公告)日：1997-10-14
申请号：US55259
申请日：1996-06-03
申请人： Kenichiro Kono , Masayoshi Tsuchiya , Ryuta Kanno , Tsutomu Tsuchiya
设计人： Kenichiro Kono , Masayoshi Tsuchiya , Ryuta Kanno , Tsutomu Tsuchiya

7. 发明授权

US5527781A 4-O-(aminoglycosyl)- or 4,6-di-O-(aminoglycosyl)-2,5-dideoxy-5,5-difluorostreptamine derivatives 失效
标题翻译： 4-O-（氨基糖基） - 或4,6-二-O-（氨基糖基）-2,5-二脱氧-5,5-二氟色胺衍生物
公开(公告)号：US5527781A
公开(公告)日：1996-06-18
申请号：US39447
申请日：1993-04-21
申请人： Tomio Takeuchi , Sumio Umezawa , Tsutomu Tsuchiya , Tetsuo Shitara , Shunzo Fukatsu , Eijiro Umemura
发明人： Tomio Takeuchi , Sumio Umezawa , Tsutomu Tsuchiya , Tetsuo Shitara , Shunzo Fukatsu , Eijiro Umemura
IPC分类号： A01N43/16 , A61K31/70 , A61K31/7028 , A61K31/7034 , A61K31/7036 , A61P31/04 , C07H15/224 , C07H15/234 , C07H15/236 , C07H15/22
CPC分类号： C07H15/224 , C07H15/234 , C07H15/236 , Y02P20/55
摘要： As new compounds are now synthetized 5-deoxy-5,5-difluoro derivatives of aminoglycosidic antibiotics of neamine, kanamycin A-series, kanamycin B-series, gentamicin-series and seldomycin-series. Further, the 1-N-(.alpha.-hydroxy-.omega.-aminoalkanoyl) derivatives are synthetized from 5-deoxy-5,5-difluorokanamycins A and B, as well as their analogues now obtained. The 5-deoxy-5,5-difluoro derivatives of the aminoglycosidic antibiotics now provided according to this invention have such antibacterial activities enhanced much more than or equal to those of the respectively corresponding parent aminoglycosidic antibiotics, while these 5-deoxy-5,5-difluoro derivatives exhibit values of the 50% lethal dosage (LD.sub.50) which are improved remarkably better when they are intravenously administered to mice, so that they have remarkedly reduced toxicities to mammals.
摘要翻译： PCT No.PCT / JP91 / 01115 Sec。 371日期：1993年4月21日 102（e）日期1993年4月21日PCT 1991年8月22日提交PCT公布。出版物WO92 / 03460 日期为199年3月3日。作为新化合物，目前合成了新胺，卡那霉素A系列，卡那霉素B系列，庆大霉素系列和青霉素系列氨基糖苷类抗生素的5-脱氧-5,5-二氟衍生物。此外，1-N-（α-羟基ω-氨基烷酰基）衍生物由5-脱氧-5,5-二氟吗啉霉素A和B以及它们现在获得的类似物合成。现在根据本发明提供的氨基糖苷类抗生素的5-脱氧-5,5-二氟衍生物具有比分别对应的母体氨基糖苷类抗生素的这些抗菌活性更强或更多的抗菌活性，而这些5-脱氧-5,5 二氟衍生物显示50％致死剂量（LD50）的值，当它们静脉内施用于小鼠时，其显着改善，从而显着降低对哺乳动物的毒性。

8. 发明授权

US4945081A Mycaminosyl tylonolide derivatives 失效
标题翻译：碳霉糖太乐内酯衍生物
公开(公告)号：US4945081A
公开(公告)日：1990-07-31
申请号：US232904
申请日：1988-08-16
申请人： Hamao Umezawa , Sumio Umezawa , Tsutomu Tsuchiya , Tomio Takeuchi , Akihiro Tanaka , Shuichi Sakamoto
发明人： Hamao Umezawa , Sumio Umezawa , Tsutomu Tsuchiya , Tomio Takeuchi , Akihiro Tanaka , Shuichi Sakamoto
IPC分类号： A61K31/70 , A61K31/7042 , A61K31/7048 , A61P31/04 , C07H17/08
CPC分类号： C07H17/08 , Y02P20/55
摘要： Mycaminosyl tylonolide derivatives represented by the following general formula ##STR1## (wherein R.sup.1 denotes hydroxyl group, a lower alkanoyloxy group, benzyloxy group, azido group, or amino group which may optionally be substituted with a lower alkyl or a lower alkanoyl radical; R.sup.2 stands for hydrogen atom or hydroxyl group; R.sup.3 expresses hydrogen atom or formyl group; and means a double bond or a radical represented by ##STR2## and salts thereof.

9. 发明授权

US4873225A 1-n-(4-amino-3-fluoro-2-hydroxybutyryl)-kanamycins 失效
标题翻译： 1-正（4-氨基-3-氟-2-羟基丁酰） - 卡那霉素
公开(公告)号：US4873225A
公开(公告)日：1989-10-10
申请号：US158628
申请日：1988-02-22
申请人： Sumio Umezawa , Tsutomu Tsuchiya , Tomio Takeuchi , Kazuo Umezawa , Yoshiaki Takahashi , Tetsuo Shitara , Yoshihiko Kobayashi , Yasushi Takagi
发明人： Sumio Umezawa , Tsutomu Tsuchiya , Tomio Takeuchi , Kazuo Umezawa , Yoshiaki Takahashi , Tetsuo Shitara , Yoshihiko Kobayashi , Yasushi Takagi
IPC分类号： C07H15/234 , A61K31/70 , A61K31/7028 , A61K31/7034 , A61K31/7036 , A61P31/04 , C07H15/236
CPC分类号： C07H15/234
摘要： As new compound are now provided ten compounds, namely 1-N-{(2R,3R)-4-amino-3-fluoro-2-hydroxybutyryl}kanamycin A; 1-N-{(2R,3R)-4-amino-3-fluoro-2-hydroxybutyryl}-2',3'-dideoxykanamycin A; 1-N-{(2R,3R)-4-amino-3-fluoro-2-hydroxybutyryl}-2',3'-dideoxy-2'-fluorokanamycin A; 1-N-{(2R,3R)-4-amino-3-fluoro-2-hydroxybutyryl}-5-deoxy-5-fluorokanamycin A; 1-N-{(2R,3R)-4-amino-3-fluoro-2-hydroxybutyryl}-kanamycin B; 1-N-{(2R,3R)-4-amino-3-fluoro-2-hydroxybutyryl}-3'-deoxykanamycin B; 1-N-{(2R,3R)-4-amino-3-fluoro-2-hydroxybutyryl}-3',4'-dideoxykanamycin B; 1-N-{(2R,3R) -4-amino-3-fluoro-2-hydroxybutyryl}-5-deoxy-5-fluorokanamycin B; 1-N-{(2R,3R)-4-amino-3-fluoro-2-hydroxybutyryl}-5,3'-dideoxy-5-fluorokanamycin B; and 1-N{(2R,3R)-4-amino-3-fluoro-2-hydroxybutyryl}-5,3',4'-trideoxy-5-fluorokanamycin B, which are all useful as antibacterial agent in the therapeutic treatment of bacterial infections.

10. 发明授权

US4634688A 3'-fluoro-3'-deoxykanamycin A 失效
标题翻译： 3'-氟-3'-脱氧卡那霉素A
公开(公告)号：US4634688A
公开(公告)日：1987-01-06
申请号：US758819
申请日：1985-07-25
申请人： Hamao Umezawa , Sumio Umezawa , Tsutomu Tsuchiya , Yoshiaki Takahashi
发明人： Hamao Umezawa , Sumio Umezawa , Tsutomu Tsuchiya , Yoshiaki Takahashi
IPC分类号： C07H15/234 , A61K31/70 , A61K31/7028 , A61K31/7034 , A61K31/7036 , A61P31/04 , C07H9/04 , C07H15/236 , A61K31/71 , C07H15/22
CPC分类号： C07H15/234 , C07H9/04 , Y02P20/55
摘要： A new compound, 3'-fluoro-3'-deoxykanamycin A is now provided, which is active against gram-negative and gram-positive bacteria, including kanamycin-resistant strains of bacteria and is useful as antibacterial agent for therapeutic treatment of bacterial infections. This new compound is produced by a process comprising reacting a 6-azido-2,4-di-O-protected-3,6-dideoxy-3-fluoro-.alpha.-D-glucopyranosyl bromide with the 4-hydroxyl group of a 6-O-(2'-O-protected-3'-N-protected-3'-amino-4',6'-di-O-protected-3'-deoxy-.alpha.-D-glucopyranosyl)-1,3-bis-N-protected-2-deoxystreptamine, reducing the azido group of the resulting reaction product into an amino group, and removing the remaining protective groups from the reduction product.
摘要翻译：现在提供了一种新的化合物3'-氟-3'-脱氧卡那霉素A，其对革兰氏阴性和革兰氏阳性细菌具有活性，包括卡那霉素抗性细菌菌株，并且可用作细菌感染的治疗性治疗用抗菌剂。该新化合物通过包括使6-叠氮基-2,4-二-O-保护的3,6-二脱氧-3-氟-α-D-吡喃葡萄糖基溴与6位的4-羟基反应的方法制备 -O-（2'-O-保护的3'-N-保护的3'-氨基-4'，6'-二-O-保护的-3'-脱氧-α-D-吡喃葡萄糖基） 3-双-N-保护的2-脱氧链霉胺，将所得反应产物的叠氮基还原成氨基，并从还原产物中除去剩余的保护基团。

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