专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明专利

BR5900623U 未知
公开(公告)号：BR5900623U
公开(公告)日：1980-11-11
申请号：BR5900623
申请日：1979-05-09
申请人： TSUTOMU NAGATA
发明人： TSUTOMU NAGATA
IPC分类号： A45F3/04 , A47D13/08

2. 发明专利

BR5801642U 未知
公开(公告)号：BR5801642U
公开(公告)日：1980-05-27
申请号：BR5801642
申请日：1978-11-21
申请人： TSUTOMU NAGATA
发明人： TSUTOMU NAGATA
IPC分类号： A61F5/01

3. 发明授权

US10086649B2 Bearing device for wheel 有权
公开(公告)号：US10086649B2
公开(公告)日：2018-10-02
申请号：US14771555
申请日：2014-02-14
申请人： Takayuki Norimatsu , Tsutomu Nagata
发明人： Takayuki Norimatsu , Tsutomu Nagata
IPC分类号： B60B27/00 , F16C35/06 , F16C19/18 , F16D1/076 , F16C35/063 , F16D1/072 , F16B39/10 , F16D1/10 , F16D3/223
摘要： A bearing device for a wheel has a wheel bearing including inner and outer rings, a hub wheel, and balls between outer raceway surfaces of the outer ring and inner raceway surfaces of the hub wheel and the inner ring. A stem section is fitted into an inner diameter of the hub wheel to couple a constant velocity universal joint to the wheel bearing through a screw fastening structure so that a shoulder portion of an outer joint member abuts against a crimped portion of the hub wheel. Projecting portions formed on the stem section are press-fitted into the hub wheel having depressed portions formed to interfere with the projecting portions, and a shape of the projecting portions is transferred to the hub wheel providing a projection and depression fitting structure in which the projecting and depressed portions are in close contact at an entire fitting contact portion therebetween.

4. 发明申请

US20130230501A9 Cycloalkyl-Substituted Imidazole Derivative 有权
标题翻译：环烷基取代咪唑衍生物
公开(公告)号：US20130230501A9
公开(公告)日：2013-09-05
申请号：US13550366
申请日：2012-07-16
申请人： Tsutomu Nagata , Masahiro Inoue , Yuka Ashida , Kengo Noguchi , Makoto Ono
发明人： Tsutomu Nagata , Masahiro Inoue , Yuka Ashida , Kengo Noguchi , Makoto Ono
IPC分类号： A61K31/4172 , C07D405/12 , C07D403/06 , C07D401/12 , A61K31/4178 , A61K31/4439 , A61K38/43 , C07D233/90 , C07C271/22 , A61P7/02 , A61P9/10 , A61P3/10 , A61P35/00 , A61P11/00 , A61P1/16 , A61P27/02 , A61P35/04 , C07D233/64
CPC分类号： C07D405/12 , A61K9/0014 , A61K9/0019 , A61K9/06 , A61K9/08 , A61K9/10 , A61K9/2054 , A61K9/2059 , A61K9/4866 , A61K9/4875 , A61K31/417 , A61K31/4172 , A61K31/4178 , A61K31/4439 , A61K45/06 , A61K47/38 , C07D233/64 , C07D233/90 , C07D401/12 , C07D403/06 , C07D413/06
摘要： A compound represented by the following general formula (I) or a pharmacologically acceptable salt thereof, wherein A represents a C3 to C12 cycloalkyl group which may be substituted by one to three selected from a fluoro group, a hydroxy group, a C1 to C6 alkyl group, etc; R1, R2, and R3 each independently represent a hydrogen atom, a fluoro group, or a C1 to C6 alkyl group; R4 represents a hydrogen atom or a prodrug group; and Y represents —CH2—CHR5—CH2—NHR6 (wherein R5 represents a hydrogen atom, a C1 to C6 alkyl group, or a C1 to C6 alkoxy group, and R6 represents a hydrogen atom or a prodrug group), or the like exhibits excellent TAFIa inhibitory activity and is useful as a therapeutic drug for myocardial infarction, angina pectoris, acute coronary syndrome, cerebral infarction, deep vein thrombosis, pulmonary embolism, and the like.
摘要翻译：由以下通式（I）表示的化合物或其药理学上可接受的盐，其中A表示可以被1-3个选自氟基，羟基，C 1至C 6烷基中的1至3个取代的C 3至C 12环烷基集团等; R 1，R 2和R 3各自独立地表示氢原子，氟基或C 1至C 6烷基; R4表示氢原子或前药基团; Y表示-CH 2 -CHR 5 -CH 2 -NHR 6（其中，R5表示氢原子，C1〜C6烷基或C1〜C6烷氧基，R6表示氢原子或前药基）等表现出优良的TAFIa抑制活性，可用作心肌梗塞，心绞痛，急性冠状动脉综合征，脑梗死，深静脉血栓形成，肺栓塞等治疗药物。

5. 发明授权

US08088796B2 Triamine derivative 失效
标题翻译：三胺衍生物
公开(公告)号：US08088796B2
公开(公告)日：2012-01-03
申请号：US11909802
申请日：2006-03-31
申请人： Akiyoshi Mochizuki , Tsutomu Nagata
发明人： Akiyoshi Mochizuki , Tsutomu Nagata
IPC分类号： A61K31/444 , C07D419/04
CPC分类号： C07D413/14 , C07D471/04 , C07D513/04
摘要： An object of the present invention is to provide a novel compound which has a potent inhibitory effect on FXa and exhibits an excellent antithrombotic effect when orally administered. The present invention provides a compound represented by the following general formula (1): wherein R1 and R2 each independently represent a hydrogen atom, a hydroxy group, an alkyl group or an alkoxy group; Q1 represents a saturated or unsaturated bicyclic or tricyclic fused hydrocarbon group which may be substituted, a saturated or unsaturated bicyclic or tricyclic fused heterocyclic group which may be substituted, or the like; Q2 represents a single bond, a straight-chained or branched alkylene group having 1 to 6 carbon atoms, a straight-chained or branched alkenylene group having 2 to 6 carbon atoms, or the like; R3 and R4 each represent an alkyl group, or the like; m and n each represent an integer from 0 to 3; Q4 represents an aryl group; and T0 and T1 each represent a carbonyl group or the like, and a medicine containing the compound.
摘要翻译：本发明的目的是提供一种对FXa具有强效抑制作用的新型化合物，并且在口服时具有优异的抗血栓形成作用。本发明提供由以下通式（1）表示的化合物：其中R 1和R 2各自独立地表示氢原子，羟基，烷基或烷氧基; Q1表示可以被取代的饱和或不饱和的二环或三环稠合烃基，可被取代的饱和或不饱和的双环或三环稠合杂环基等; Q2表示单键，具有1〜6个碳原子的直链或支链亚烷基，碳原子数2〜6的直链或支链亚烯基等; R3和R4各自表示烷基等; m和n各自表示0至3的整数; Q 4表示芳基; 并且T0和T1各自表示羰基等，以及含有该化合物的药物。

6. 发明申请

US20090281074A1 DRUG COMPOSITIONS AND METHODS FOR PREVENTING AND TREATING THROMBOSIS OR EMBOLISM 审中-公开
标题翻译：药物组合物和预防和治疗血栓形成或栓塞的方法
公开(公告)号：US20090281074A1
公开(公告)日：2009-11-12
申请号：US12250586
申请日：2008-10-14
申请人： Toshiharu OHTA , Satoshi Komoriya , Toshiharu Yoshino , Kouichi Outo , Yumi Nakamoto , Hiroyuki Naito , Akiyoshi Mochizuki , Tsutomu Nagata , Hideyuki Kanno , Noriyasu Haginoya , Kenji Yoshikawa , Masatoshi Nagamochi , Syozo Kobayashi , Makoto Ono
发明人： Toshiharu OHTA , Satoshi Komoriya , Toshiharu Yoshino , Kouichi Outo , Yumi Nakamoto , Hiroyuki Naito , Akiyoshi Mochizuki , Tsutomu Nagata , Hideyuki Kanno , Noriyasu Haginoya , Kenji Yoshikawa , Masatoshi Nagamochi , Syozo Kobayashi , Makoto Ono
IPC分类号： A61K31/397 , A61K31/437 , A61K31/502 , A61K31/5377 , A61K31/55
CPC分类号： C07D498/04 , C07D213/75 , C07D401/12 , C07D401/14 , C07D409/04 , C07D409/12 , C07D413/12 , C07D413/14 , C07D417/14 , C07D471/04 , C07D487/04 , C07D513/14 , C07D519/00
摘要： Drug compositions containing a substituted diamine compound represented by formula (1): Q1-Q2-r-N(R1)-Q3-N(R2) (1) wherein Q3 represents the following group wherein Q5 represents an alkylene group having 4 carbon atoms, R3 represents a hydrogen atom, and R4 represents a 3-6 membered heterocyclic group which may be substituted; are useful for preventing and/or treating cerebral infarction, cerebral embolism, myocardial infarction, angina pectoris, pulmonary infarction, pulmonary embolism, Buerger's disease, deep venous thrombosis, disseminated intravascular coagulation syndrome, thrombus formation after artificial valve or joint replacement, thrombus formation and reocclusion after angioplasty, systemic inflammatory response syndrome (SIRS), multiple organ dysfunction syndrome (MODS), thrombus formation during extracorporeal circulation, or blood clotting upon blood drawing.
摘要翻译：含有式（1）表示的取代二胺化合物的药物组合物：Q1-Q2-rN（R1）-Q3-N（R2）（1）其中Q3表示以下基团，其中Q5表示具有4个碳原子的亚烷基，R3 表示氢原子，R4表示可以被取代的3-6元杂环基; 可用于预防和/或治疗脑梗死，脑栓塞，心肌梗死，心绞痛，肺梗塞，肺栓塞，Buerger病，深静脉血栓形成，弥散性血管内凝血综合征，人工瓣膜或关节置换后血栓形成，血栓形成和血管成形术后再闭塞，全身炎症反应综合征（SIRS），多器官功能障碍综合征（MODS），体外循环期间的血栓形成或血液抽血时的凝血。

7. 发明授权

US07342014B2 Diamine derivatives 有权
标题翻译：二胺衍生物
公开(公告)号：US07342014B2
公开(公告)日：2008-03-11
申请号：US10773344
申请日：2004-02-09
申请人： Toshiharu Ohta , Satoshi Komoriya , Toshiharu Yoshino , Kouichi Uoto , Yumi Nakamoto , Hiroyuki Naito , Akiyoshi Mochizuki , Tsutomu Nagata , Hideyuki Kanno , Noriyasu Haginoya , Kenji Yoshikawa , Masatoshi Nagamochi , Syozo Kobayashi , Makoto Ono
发明人： Toshiharu Ohta , Satoshi Komoriya , Toshiharu Yoshino , Kouichi Uoto , Yumi Nakamoto , Hiroyuki Naito , Akiyoshi Mochizuki , Tsutomu Nagata , Hideyuki Kanno , Noriyasu Haginoya , Kenji Yoshikawa , Masatoshi Nagamochi , Syozo Kobayashi , Makoto Ono
IPC分类号： A61K31/50 , A61K31/44 , A61K31/445 , C07D471/02 , C07D401/00
CPC分类号： C07D513/04 , C07D209/42
摘要： A compound represented by the general formula (1): Q1-Q2-T0-N(R1)-Q3-N(R2)-T1-Q4 (1) wherein R1 and R2 are hydrogen atoms or the like; Q1 is a saturated or unsaturated, 5- or 6-membered cyclic hydrocarbon group which may be substituted, or the like; Q2 is a single bond or the like; Q3 is a group in which Q5 is an alkylene group having 1 to 8 carbon atoms, or the like; and T0 and T1 are carbonyl groups or the like; a salt thereof, a solvate thereof, or an N-oxide thereof. The compound is useful as an agent for preventing and/or treating cerebral infarction, cerebral embolism, myocardial infarction, angina pectoris, pulmonary infarction, pulmonary embolism, Buerger's disease, deep venous thrombosis, disseminated intravascular coagulation syndrome, thrombus formation after valve or joint replacement, thrombus formation and reocclusion after angioplasty, systemic inflammatory response syndrome (SIRS), multiple organ dysfunction syndrome (MODS), thrombus formation during extracorporeal circulation, or blood clotting upon blood drawing.
摘要翻译：由通式（1）表示的化合物：<？in-line-formula description =“In-line Formulas”end =“lead”？> Q ^{1 -N（R 1） - N（R 2） - N（R 2） - T （1）<？in-line-formula description =“In-line Formulas”end =“tail”？>其中R 1 < / SUP>和R 2是氢原子等; Q 1是可被取代的饱和或不饱和的5或6元环烃基，等等; Q 2是单键等; Q 3是其中Q 5是具有1〜8个碳原子的亚烷基等的基团; T 0和T 1是羰基等; 其盐，其溶剂合物或其N-氧化物。该化合物可用作预防和/或治疗脑梗塞，脑栓塞，心肌梗死，心绞痛，肺梗塞，肺栓塞，Buerger病，深静脉血栓形成，弥散性血管内凝血综合征，瓣膜或关节置换后血栓形成，血管成形术后的血栓形成和再闭塞，全身炎症反应综合征（SIRS），多器官功能障碍综合征（MODS），体外循环期间的血栓形成或血液抽血时的凝血。}

8. 发明授权

US07333746B2 Developing device and image forming apparatus provided with same 有权
标题翻译：显影装置和图像形成装置
公开(公告)号：US07333746B2
公开(公告)日：2008-02-19
申请号：US11249746
申请日：2005-10-14
申请人： Tsutomu Nagata , Takahiko Kimura
发明人： Tsutomu Nagata , Takahiko Kimura
IPC分类号： G03G15/08
CPC分类号： G03G15/0817 , G03G15/0942 , G03G2215/0609
摘要： A developing device is arranged such that Dg
摘要翻译：布置开发装置使得Dg <3d <3Dg和3Dg

9. 发明申请

US20050245565A1 Diamine derivatives 审中-公开
标题翻译：二胺衍生物
公开(公告)号：US20050245565A1
公开(公告)日：2005-11-03
申请号：US10481629
申请日：2002-06-20
申请人： Toshiharu Ohta , Satoshi Komoriya , Toshiharu Yoshino , Kouichi Uoto , Yumi Nakamoto , Hiroyuki Naito , Akiyoshi Mochizuki , Tsutomu Nagata , Hideyuki Kanno , Noriyasu Haginoya , Kenji Yoshikawa , Masatoshi Nagamochi , Syozo Kobayashi , Makoto Ono
发明人： Toshiharu Ohta , Satoshi Komoriya , Toshiharu Yoshino , Kouichi Uoto , Yumi Nakamoto , Hiroyuki Naito , Akiyoshi Mochizuki , Tsutomu Nagata , Hideyuki Kanno , Noriyasu Haginoya , Kenji Yoshikawa , Masatoshi Nagamochi , Syozo Kobayashi , Makoto Ono
IPC分类号： C07D401/12 , A61K20060101 , A61P20060101 , A61P7/02 , A61P9/00 , A61P9/10 , A61P29/00 , C07D20060101 , C07D209/42 , C07D401/14 , C07D417/12 , C07D417/14 , C07D487/04 , C07D495/04 , C07D498/04 , C07D513/04 , C07D513/14 , C07D519/00 , C07K5/06 , C07K5/08 , C07D471/02 , A61K31/4745 , C07D43/02
CPC分类号： C07D401/12 , A61K31/428 , A61K31/429 , A61K31/4365 , A61K31/437 , A61K31/4439 , A61K31/444 , A61K31/454 , A61K31/4545 , C07D209/42 , C07D401/14 , C07D417/12 , C07D417/14 , C07D487/04 , C07D495/04 , C07D498/04 , C07D513/04 , C07D513/14 , C07K5/06191 , C07K5/0827
摘要： A compound represented by the general formula (1): Q1-Q2-T0-N(R1)-Q3-N(R2) -T1-Q4 (1) wherein R1 and R2 are hydrogen atoms or the like; Q1 is a saturated or unsaturated, 5- or 6-membered cyclic hydrocarbon group which may be substituted, or the like; Q2 is a single bond or the like; Q3 is a group in which Q5 is an alkylene group having 1 to 8 carbon atoms, or the like; and T0 and T1 are carbonyl groups or the like; a salt thereof, a solvate thereof, or an N-oxide thereof. The compound is useful as an agent for preventing and/or treating cerebral infarction, cerebral embolism, myocardial infarction, angina pectoris, pulmonary infarction, pulmonary embolism, Buerger's disease, deep venous thrombosis, disseminated intravascular coagulation syndrome, thrombus formation after valve or joint replacement, thrombus formation and reocclusion after angioplasty, systemic inflammatory response syndrome (SIRS), multiple organ dysfunction syndrome (MODS), thrombus formation during extracorporeal circulation, or blood clotting upon blood drawing.
摘要翻译：由通式（1）表示的化合物：<？in-line-formula description =“In-line Formulas”end =“lead”？> Q ^{1 -O（R 1） - N 3 - （R 2） - N（R 2） - T （1）<？in-line-formula description =“In-line Formulas”end =“tail”？>其中R 1 < / SUP>和R 2是氢原子等; Q 1是可被取代的饱和或不饱和的5或6元环烃基，等等; Q 2是单键等; Q 3是其中Q 5是具有1〜8个碳原子的亚烷基等的基团; T 0和T 1是羰基等; 其盐，其溶剂合物或其N-氧化物。该化合物可用作预防和/或治疗脑梗塞，脑栓塞，心肌梗死，心绞痛，肺梗塞，肺栓塞，Buerger病，深静脉血栓形成，弥散性血管内凝血综合征，瓣膜或关节置换后血栓形成，血管成形术后的血栓形成和再闭塞，全身炎症反应综合征（SIRS），多器官功能障碍综合征（MODS），体外循环期间的血栓形成或血液抽血时的凝血。}

10. 外观设计

USD462713S1 Developing unit for an image forming apparatus 失效
标题翻译：用于图像形成装置的显影单元
公开(公告)号：USD462713S1
公开(公告)日：2002-09-10
申请号：US29148030
申请日：2001-09-14
申请人： Naotaka Funayama , Jun Yamaguchi , Tsutomu Nagata , Yoshiaki Sanada , Takahiko Kimura
设计人： Naotaka Funayama , Jun Yamaguchi , Tsutomu Nagata , Yoshiaki Sanada , Takahiko Kimura

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式