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1. 发明专利

JP2006096336A Wheel rim for vehicle 审中-公开
标题翻译：车轮车轮
公开(公告)号：JP2006096336A
公开(公告)日：2006-04-13
申请号：JP2005274146
申请日：2005-09-21
申请人： Ting-Fang Wang , 亭芳王
发明人： WANG TING-FANG
IPC分类号： B60B21/02 , B60B3/04 , B60B21/00
CPC分类号： B60B3/002 , B60B3/10 , B60B23/10 , Y10T29/49524
摘要： PROBLEM TO BE SOLVED: To provide a wheel rim for a vehicle with high strength and long use life in addition to light weight. SOLUTION: The wheel rim 4 for the vehicle has a wheel rim part 41, integrally molded to a cylindrical body 46 having both opposed ends by deep drawing working, in which a rib 42 bent like a pleat projected from an outer peripheral side to an inner peripheral side central direction is formed on one end side of a peripheral surface part of the cylindrical body 46 and a plurality of through holes 421 directed in a lateral direction are provided on a side surface of the bent rib 42 with a predetermined interval. COPYRIGHT: (C)2006,JPO&NCIPI
摘要翻译：要解决的问题：除了重量轻之外，为车辆提供高强度和长使用寿命的轮辋。解决方案：用于车辆的轮辋4具有轮辋部分41，其通过深冲加工一体地模制成具有两相对端的圆筒体46，其中弯曲成从外周侧突出的褶皱的肋42 在圆筒体46的周面部的一端侧形成有内周侧中心方向，并且在弯曲肋42的侧面以规定的间隔设置有朝向横方向的多个贯通孔421 。版权所有（C）2006，JPO＆NCIPI

2. 发明授权

US08034910B2 SUMO fusion protein expression system for producing native proteins 有权
标题翻译：用于产生天然蛋白质的SUMO融合蛋白表达系统
公开(公告)号：US08034910B2
公开(公告)日：2011-10-11
申请号：US12436211
申请日：2009-05-06
申请人： Ting-Fang Wang
发明人： Ting-Fang Wang
IPC分类号： C07H21/02 , C12P21/06 , A23J1/00
CPC分类号： C07K1/22 , C07K2319/20 , C07K2319/21 , C07K2319/23 , C07K2319/24 , C07K2319/50 , C12P21/02 , C12P21/06
摘要： A simple and efficient SUMO fusion protein expression system for producing native proteins.
摘要翻译：一种用于产生天然蛋白质的简单有效的SUMO融合蛋白表达系统。

3. 发明申请

US20100183649A1 METHOD OF PRODUCING VIRUS-LIKE PARTICLES OF PICORNAVIRUS USING A SMALL-UBIQUITIN-RELATED FUSION PROTEIN EXPRESSION SYSTEM 有权
标题翻译：使用与小蛋白质相关的融合蛋白表达系统生产拟南芥的病毒颗粒的方法
公开(公告)号：US20100183649A1
公开(公告)日：2010-07-22
申请号：US12683568
申请日：2010-01-07
申请人： Ting-Fang Wang , Shu-Mei Liang
发明人： Ting-Fang Wang , Shu-Mei Liang
IPC分类号： A61K39/135 , C12P21/00 , C12P21/06 , A61P31/12 , C12N1/20
CPC分类号： A61K39/135 , A61K39/12 , A61K2039/5258 , A61K2039/552 , C07K2319/21 , C07K2319/35 , C07K2319/95 , C12N7/00 , C12N2770/32123 , C12N2770/32134
摘要： A method for producing picornaviral capsid protein complexes (e.g., picornavirus like particles) in E. coli using a small-ubiquitin-related fusion protein expression system and an E. coli strain used in practicing this method. Also disclosed is use of the picornaviral capsid protein complexes like thus prepared for eliciting immune responses.
摘要翻译：使用小泛素相关融合蛋白表达系统和用于实施该方法的大肠杆菌菌株在大肠杆菌中生产小核糖核酸病毒衣壳蛋白复合物（例如，小核糖核酸病毒样颗粒）的方法。还公开了如此制备的小核糖核酸病毒衣壳蛋白复合物用于引发免疫应答。

4. 发明申请

US20060061209A1 Vehicle wheel rim 审中-公开
标题翻译：车轮轮辋
公开(公告)号：US20060061209A1
公开(公告)日：2006-03-23
申请号：US11193109
申请日：2005-07-30
申请人： Ting-Fang Wang
发明人： Ting-Fang Wang
IPC分类号： B60B3/10
CPC分类号： B60B3/002 , B60B3/10 , B60B23/10 , Y10T29/49524
摘要： A vehicle wheel rim includes a wheel rim body having a tubular wall formed by deep drawing and having two opposite ends, and an annular protrusion formed as one piece with and projecting radially and inwardly from the tubular wall between the two ends. The annular protrusion has a first bent part which is bent inwardly from the tubular wall, and a second bent part which is bent outwardly from the first bent part. The first and second bent parts are flattened to abut each other. The annular protrusion further has a plurality of angularly spaced-apart through holes that extend through the first and second bent parts.
摘要翻译：车轮轮缘包括轮辋主体，其具有通过深拉制成并具有两个相对端的管状壁，以及形成为一体的环形突起，并且从两端之间的管状壁径向向内突出。环形突起具有从管状壁向内弯曲的第一弯曲部和从第一弯曲部向外弯曲的第二弯曲部。第一和第二弯曲部分被平坦化以彼此邻接。环形突起还具有延伸穿过第一和第二弯曲部分的多个角度间隔开的通孔。

5. 发明申请

US20100035300A1 Producing a Target Protein Using Intramolecular Cleavage by TEV Protease 审中-公开
标题翻译：通过TEV蛋白酶分子内切割产生靶蛋白
公开(公告)号：US20100035300A1
公开(公告)日：2010-02-11
申请号：US11364716
申请日：2006-02-27
申请人： Andrew H.-J. Wang , Ting-Fang Wang , Yan-Ping Shih , Hui-Chung Wu , Su-Ming Hu
发明人： Andrew H.-J. Wang , Ting-Fang Wang , Yan-Ping Shih , Hui-Chung Wu , Su-Ming Hu
IPC分类号： C12P21/00 , C12N1/20
CPC分类号： C12P21/06 , C07K2319/50 , C12N9/503
摘要： A cis-TEVP fusion protein including a TEVP protease, a TEVP cleavage site and a target protein provide a platform for expression of the target protein. A trans-TEVP fusion protein including a TEVP cleavage site and a target protein, the amino-terminal portion of the target protein adjacent to the C-terminal portion of the TEVP cleavage site, the amino acidic residue in position P2 of the TEVP cleavage site being a Valine also produces the target protein by the same process. A cis-TEVP fusion protein system comprising the first fusion protein and a suitable host cell; a trans-TEVP fusion protein system comprising the second fusion protein and a suitable host cell; associated methods to produce target proteins, and kits of parts are also disclosed herein.
摘要翻译：包含TEVP蛋白酶，TEVP切割位点和靶蛋白的顺式TEVP融合蛋白提供靶蛋白表达的平台。包含TEVP切割位点和靶蛋白的TETEP融合蛋白，与TEVP切割位点的C末端部分相邻的靶蛋白的氨基末端部分，TEVP切割位点P2位置的氨基酸残基作为缬氨酸也通过相同的过程产生靶蛋白。包含第一融合蛋白和合适宿主细胞的顺-TEVP融合蛋白系统; 包含第二融合蛋白和合适的宿主细胞的反TEVP融合蛋白系统; 本文还公开了产生靶蛋白的相关方法和成分的试剂盒。

6. 发明申请

US20090280535A1 SUMO Fusion Protein Expression System for Producing Native Proteins 有权
标题翻译： SUMO融合蛋白表达系统产生天然蛋白质
公开(公告)号：US20090280535A1
公开(公告)日：2009-11-12
申请号：US12436211
申请日：2009-05-06
申请人： Ting-Fang Wang
发明人： Ting-Fang Wang
IPC分类号： C12P21/00 , C12N15/00 , C07K1/00
CPC分类号： C07K1/22 , C07K2319/20 , C07K2319/21 , C07K2319/23 , C07K2319/24 , C07K2319/50 , C12P21/02 , C12P21/06
摘要： A simple and efficient SUMO fusion protein expression system for producing native proteins.
摘要翻译：一种用于产生天然蛋白质的简单有效的SUMO融合蛋白表达系统。

7. 发明申请

US20090280531A1 Preparation of Soluble Capsid Proteins of Picornaviruses Using SUMO Fusion Technology 审中-公开
标题翻译：使用SUMO融合技术制备微小核糖核酸病毒的可溶性衣壳蛋白
公开(公告)号：US20090280531A1
公开(公告)日：2009-11-12
申请号：US12436215
申请日：2009-05-06
申请人： Ting-Fang Wang
发明人： Ting-Fang Wang
IPC分类号： C12P21/00 , C07H21/04
CPC分类号： C07K14/005 , C07K2319/21 , C12N2770/32122 , C12N2800/101
摘要： A method of producing a soluble capsid protein of a picornavirus using a novel and efficient SUMO fusion protein expression system.
摘要翻译：使用新型高效SUMO融合蛋白表达系统生产小核糖核酸病毒的可溶性衣壳蛋白的方法。

8. 发明授权

US08663951B2 Method of producing virus-like particles of picornavirus using a small-ubiquitin-related fusion protein expression system 有权
标题翻译：使用小泛素相关融合蛋白表达系统生产小核糖核酸病毒样颗粒的方法
公开(公告)号：US08663951B2
公开(公告)日：2014-03-04
申请号：US12683568
申请日：2010-01-07
申请人： Ting-Fang Wang , Shu-Mei Liang
发明人： Ting-Fang Wang , Shu-Mei Liang
IPC分类号： C12N15/41 , A61K39/125
CPC分类号： A61K39/135 , A61K39/12 , A61K2039/5258 , A61K2039/552 , C07K2319/21 , C07K2319/35 , C07K2319/95 , C12N7/00 , C12N2770/32123 , C12N2770/32134
摘要： A method for producing picornaviral capsid protein complexes (e.g., picornavirus like particles) in E. coli using a small-ubiquitin-related fusion protein expression system and an E. coli strain used in practicing this method. Also disclosed is use of the picornaviral capsid protein complexes like thus prepared for eliciting immune responses.
摘要翻译：使用小泛素相关融合蛋白表达系统和用于实施该方法的大肠杆菌菌株在大肠杆菌中生产小核糖核酸病毒衣壳蛋白复合物（例如，小核糖核酸病毒样颗粒）的方法。还公开了如此制备的小核糖核酸病毒衣壳蛋白复合物用于引发免疫应答。

9. 发明授权

US07107809B2 Method for shaping a seamless aluminum wheel rim 失效
标题翻译：无缝铝轮圈成型方法
公开(公告)号：US07107809B2
公开(公告)日：2006-09-19
申请号：US10644946
申请日：2003-08-19
申请人： Ting-Fang Wang , Juei-Hung Hung
发明人： Ting-Fang Wang , Juei-Hung Hung
IPC分类号： B21D22/00
CPC分类号： B21D53/26 , Y10T29/49529
摘要： A method for manufacturing a seamless wheel rim includes the steps of deeply drawing a pre-cut circular aluminum alloy plate into a cup-shaped embryo body, punching out the bottom surface thereof to form a hollow cylinder, then putting it into an expanding-pressing female die with an expanding die cavity at both ends thereof respectively, and finally pressing and expanding both ends of the embryo body by two sets of expanding-pressing male dies to form a seamless aluminum wheel rim in sequence.
摘要翻译：制造无缝轮辋的方法包括以下步骤：将预切圆形铝合金板深入到杯形胚体内，冲出其底表面以形成中空圆筒，然后将其放入膨胀压制雌性模具分别在其两端具有扩张的模腔，并且最后通过两组扩压按压阳模挤压和扩大胚体的两端，以依次形成无缝铝轮圈。

10. 发明申请

US20070169347A1 Method of making vehicle wheel rim 审中-公开
标题翻译：制造车轮轮辋的方法
公开(公告)号：US20070169347A1
公开(公告)日：2007-07-26
申请号：US11716966
申请日：2007-03-12
申请人： Ting-Fang Wang
发明人： Ting-Fang Wang
IPC分类号： B23P17/00
CPC分类号： B60B3/002 , B60B3/10 , B60B23/10 , Y10T29/49524
摘要： A method of making a vehicle wheel rim includes the steps of: deep drawing a metal plate to form a substantially cylindrical blank having two axially opposite first and second open end portions; roll-bending a ring portion of the cylindrical blank between the open end portions so that the ring portion is bent inwardly and substantially radially; placing into a mold the cylindrical blank that has been bent; forcing upper and lower press members respectively into the open end portions of the cylindrical blank; and forming the open end portions by pressing the open end portions against a cavity wall of the mold using lateral faces of the press members, and pressing two opposite sides of the bent ring portion to form a folded annular protrusion using end faces of the press members which are transverse to the lateral faces thereof, thereby providing a wheel rim body.
摘要翻译：制造车轮轮缘的方法包括以下步骤：深拉金属板以形成具有两个轴向相对的第一和第二开口端部的大致圆柱形的坯料; 在所述开口端部之间滚动所述圆筒状坯料的环形部分，使得所述环形部分向内并大体径向弯曲; 将已弯曲的圆柱形坯料放入模具中; 分别将上下压构件分别压入圆筒坯的开口端部; 并且通过使用所述按压构件的侧面将所述开口端部压靠在所述模具的空腔壁上并且将所述弯曲环部分的两个相对侧按压以形成折叠环形突起并形成所述开口端部，所述折叠环形突起使用所述按压构件的端面其横向于其侧面，从而提供轮辋主体。

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