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1. 发明授权

US08668650B2 Pressure-sensing guidewire and sheath 有权
标题翻译：压力传感导线和护套
公开(公告)号：US08668650B2
公开(公告)日：2014-03-11
申请号：US10027154
申请日：2001-12-20
申请人： Timothy G. J. Ehr , Bruce Howard Asmus
发明人： Timothy G. J. Ehr , Bruce Howard Asmus
IPC分类号： A61B5/02 , A61B5/00
CPC分类号： A61B5/02158 , A61B5/02007 , A61B5/0215 , A61M25/0108 , A61M2025/0002 , A61M2025/0003
摘要： A pressure sensing device is provided that can monitor and measure pressure at two points in a vessel or artery without moving the outer sheath or catheter of the device. The outer sheath or catheter includes two spaced apart openings that may be positioned in a vessel or artery on opposing sides of an occlusion. The device also includes an inner elongated tube with at least one opening. The inner elongated tube is slidable with respect to the outer sheath or catheter thereby permitting the opening of the elongated tube to be moved into selective registration with one of the openings of the outer sheath. A pressure measurement may be taken through one of the openings in the outer sheath by aligning the opening of the elongated tube with said opening and, then, a second pressure reading may be taken by sliding the elongated tube within the outer sheath so that the opening of the elongated tube is in registry with the other opening of the tubular sheath. As a result, pressure measurements at two points in a vessel or artery may be taken without moving the outer sheath or catheter.
摘要翻译：提供压力感测装置，其可以在不移动装置的外护套或导管的情况下监测和测量容器或动脉中的两个点处的压力。外鞘或导管包括两个间隔开的开口，其可以位于闭塞的相对侧上的血管或动脉中。该装置还包括具有至少一个开口的内部细长管。内部细长管可相对于外部护套或导管滑动，从而允许细长管的开口移动成与外护套中的一个开口选择性对准。可以通过将细长管的开口与所述开口对准而将外部护套中的一个开口进行压力测量，然后可以通过将细长管滑动到外护套内，从而使开口细长管与管状护套的另一个开口对齐。因此，可以在不移动外护套或导管的情况下取出容器或动脉中的两个点处的压力测量。

2. 发明授权

US07731746B2 Stent 有权
公开(公告)号：US07731746B2
公开(公告)日：2010-06-08
申请号：US12025382
申请日：2008-02-04
申请人： Graig L. Kveen , Timothy G. J. Ehr , Brian J. Brown
发明人： Graig L. Kveen , Timothy G. J. Ehr , Brian J. Brown
IPC分类号： A61F2/06
CPC分类号： A61F2/915 , A61F2/91 , A61F2002/91533 , A61F2002/91541 , A61F2002/91583
摘要： A radially expandable stent comprising a plurality of spaced band-like elements and intersecting links is disclosed. The band-like elements have a generally serpentine configuration to provide continuous waves of generally sinusoidal character to each band-like element. The waves are characterized by a plurality of peaks and troughs taking a generally longitudinal direction along the cylinder such that the waves in the band-like elements open as the stent is expanded from a first diameter to a second diameter. The intersecting links are substantially U-shaped and terminate in first and second shanks. The first shank of a link emanates from a region between a peak and trough on a band-like element and the second shank of the link emanates from a region between a peak and trough on an adjacent band-like element.

3. 发明授权

US06676590B1 Catheter system having tubular radiation source 失效
标题翻译：具有管状辐射源的导管系统
公开(公告)号：US06676590B1
公开(公告)日：2004-01-13
申请号：US08984490
申请日：1997-12-08
申请人： Michael J. Urick , Timothy G. J. Ehr , Roger N. Hastings
发明人： Michael J. Urick , Timothy G. J. Ehr , Roger N. Hastings
IPC分类号： A61N500
CPC分类号： A61N5/1002 , A61M2025/0063 , A61N2005/1003 , A61N2005/1004
摘要： A radiation source for inhibiting restenosis including a radiation delivery tube having a radioactive distal region, the tube being adapted to slide over a guide wire within a radiation delivery catheter. One tube has radioactive material incorporated into the tube wall material. Another tube has radioactive material secured to the tube surface. One radiation delivery balloon catheter includes a common inflation and radiation delivery lumen, the lumen being sealed distally and having a radiation source guide wire within the lumen. The lumen is sealed from contact with bodily fluids and is filled with inflation fluid during use. In use, the catheter balloon is advanced to a site to be treated, the balloon inflated, and the radioactive tube advanced over the radiation source guide wire within the lumen.
摘要翻译：一种用于抑制再狭窄的辐射源，其包括具有放射性远侧区域的辐射递送管，所述管适于在辐射递送导管内的导丝上滑动。一管将放射性物质并入管壁材料中。另一管具有固定到管表面的放射性材料。一个辐射递送球囊导管包括公共的充气和辐射递送腔，该内腔被向远侧密封并且在内腔内具有辐射源导丝。管腔与体液接触密封，并在使用过程中充满充气液。在使用中，导管球囊前进到要治疗的部位，气囊膨胀，并且放射管在腔内的辐射源导丝上前进。

4. 发明授权

US06261319B1 Stent 失效
标题翻译：支架
公开(公告)号：US06261319B1
公开(公告)日：2001-07-17
申请号：US09111531
申请日：1998-07-08
申请人： Graig L. Kveen , Timothy G. J. Ehr , Brian J. Brown
发明人： Graig L. Kveen , Timothy G. J. Ehr , Brian J. Brown
IPC分类号： A61F206
CPC分类号： A61F2/915 , A61F2/91 , A61F2002/91533 , A61F2002/91541 , A61F2002/91583
摘要： A radially expandable stent comprising a plurality of spaced band-like elements and intersecting links is disclosed. The band-like elements have a generally serpentine configuration to provide continuous waves of generally sinusoidal character to each band-like element. The waves are characterized by a plurality of peaks and troughs taking a generally longitudinal direction along the cylinder such that the waves in the band-like elements open as the stent is expanded from a first diameter to a second diameter. The intersecting links are substantially U-shaped and terminate in first and second shanks. The first shank of a link emanates from a region between a peak and trough on a band-like element and the second shank of the link emanates from a region between a peak and trough on an adjacent band-like element.
摘要翻译：公开了一种包括多个间隔开的带状元件和相交连接件的可径向扩张的支架。带状元件具有大致蛇形结构，以向每个带状元件提供大致正弦曲线的连续波。波的特征在于沿着圆柱体大致纵向方向的多个峰和谷，使得当支架从第一直径扩展到第二直径时，带状元件中的波浪打开。交叉连接件基本上为U形并终止在第一和第二柄部中。链节的第一柄从带状元件上的峰和谷之间的区域发出，并且链节的第二柄从相邻带状元件上的峰和谷之间的区域发出。

5. 发明授权

US5441104A Fluid circulator and temperature regulator 失效
标题翻译：流体循环器和温度调节器
公开(公告)号：US5441104A
公开(公告)日：1995-08-15
申请号：US181579
申请日：1994-01-13
申请人： Timothy G. J. Ehr , Michael E. Hansen , Scott T. Breyer
发明人： Timothy G. J. Ehr , Michael E. Hansen , Scott T. Breyer
IPC分类号： B01L7/02 , G01N27/447 , F28D15/00
CPC分类号： G01N27/44708 , B01L7/02
摘要： A fluid circulator and temperature regulator apparatus for use in an electrophoresis process with a sequencing cell including a cooling jacket having an inlet and an outlet, the apparatus comprising an inlet adapted to be connected to the cooling jacket outlet, an outlet adapted to be connected to the cooling jacket inlet, a reservoir having an inlet, an outlet and a vent, a heat exchanger having an inlet and an outlet, a pump having an inlet and an outlet, the reservoir, the heat exchanger and the pump being fluidly connected in a flow path having an upstream end and a downstream end, with the reservoir being downstream of the pump, and valves operable in a first mode for connecting the downstream end of the flow path with the outlet port and for connecting the inlet port with the upstream end of the flow path, and operable in a second mode for connecting the downstream end of the flow path with the upstream end the flow path internally of the apparatus such that fluid flows from the downstream end of the flow path to the upstream end of the flow path without flowing to the outlet.
摘要翻译：一种流体循环器和温度调节器装置，用于具有测序单元的电泳过程，所述测序单元包括具有入口和出口的冷却套，所述设备包括适于连接到所述冷却套管出口的入口，适于连接到冷却套管入口，具有入口，出口和通风口的储存器，具有入口和出口的热交换器，具有入口和出口的泵，所述储存器，所述热交换器和所述泵以具有上游端和下游端的流路，其中所述储存器位于所述泵的下游，以及可操作的第一模式的阀，用于将所述流动路径的下游端与所述出口连接并将所述入口与所述上游端连接并且可以在第二模式中操作，用于将流动路径的下游端与上游端连接在设备内部的流动路径，使得流体从到流动路径的上游端的流动路径的下游端，而不流到出口。

6. 发明授权

US5323846A Fluid circulator and temperature regulator 失效
标题翻译：流体循环器和温度调节器
公开(公告)号：US5323846A
公开(公告)日：1994-06-28
申请号：US820529
申请日：1992-01-14
申请人： Timothy G. J. Ehr , Michael E. Hansen
发明人： Timothy G. J. Ehr , Michael E. Hansen
IPC分类号： B01L7/02 , G01N27/447 , F28D15/00
CPC分类号： G01N27/44708 , B01L7/02
摘要： A fluid circulator and temperature regulator apparatus for use in an electrophoresis process with a sequencing cell including a cooling jacket having an inlet and an outlet, the apparatus being adapted to be connected to the cooling jacket inlet and outlet, and the apparatus comprising a reservoir, a pump for circulating cooling fluid through the cooling jacket, and a heat exchanger for regulating the temperature of the cooling fluid, the apparatus being operable for filling and draining the reservoir, for degasifying fluid in the reservoir, and for filling and draining the cell.
摘要翻译：一种流体循环器和温度调节器装置，用于具有测序单元的电泳过程，所述测序单元包括具有入口和出口的冷却套，所述设备适于连接到所述冷却套入口和出口，并且所述设备包括储存器，用于使冷却流体通过冷却套管循环的泵，以及用于调节冷却流体温度的热交换器，该装置可操作用于填充和排出储存器，用于对储存器中的流体进行脱气，以及用于填充和排出池。

7. 发明授权

US5242568A Electrophoresis apparatus 失效
标题翻译：电泳装置
公开(公告)号：US5242568A
公开(公告)日：1993-09-07
申请号：US820558
申请日：1992-01-14
申请人： Timothy G. J. Ehr , Stephen H. Gorski , Richard K. Vitek
发明人： Timothy G. J. Ehr , Stephen H. Gorski , Richard K. Vitek
IPC分类号： G01N27/447
CPC分类号： G01N27/44704 , G01N27/44756
摘要： Electrophoresis apparatus comprising a base including a water jacket, a generally horizontal bottom plate having an upper surface, and a lower surface which is supported by the base and which extends over the water jacket, an endless gasket having a lower surface engaging the upper surface of the bottom plate, and having an upper surface, and a generally horizontal top plate having a lower surface seated on the upper surface of the gasket so as to define between the plates and inside the gasket a space adapted to contain a separation medium.
摘要翻译：电泳装置，包括一个底座，该底座包括一个水套，一个具有上表面的大体上水平的底板，以及一个由底座支撑并在水套上方延伸的下表面，一个环形衬垫，底板，并具有上表面，以及大致水平的顶板，其下表面位于垫片的上表面上，以便在板之间和垫圈内部限定适于容纳分离介质的空间。

8. 发明授权

US08668731B2 Stent 有权
标题翻译：支架
公开(公告)号：US08668731B2
公开(公告)日：2014-03-11
申请号：US13531064
申请日：2012-06-22
申请人： Graig L. Kveen , Timothy G. J. Ehr , Brian J. Brown
发明人： Graig L. Kveen , Timothy G. J. Ehr , Brian J. Brown
IPC分类号： A61F2/82
CPC分类号： A61F2/915 , A61F2/91 , A61F2002/91533 , A61F2002/91541 , A61F2002/91583
摘要： A radially expandable stent comprising a plurality of spaced band-like elements and intersecting links is disclosed. The band-like elements have a generally serpentine configuration to provide continuous waves of generally sinusoidal character to each band-like element. The waves are characterized by a plurality of peaks and troughs taking a generally longitudinal direction along the cylinder such that the waves in the band-like elements open as the stent is expanded from a first diameter to a second diameter. The intersecting links are substantially U-shaped and terminate in first and second shanks. The first shank of a link emanates from a region between a peak and trough on a band-like element and the second shank of the link emanates from a region between a peak and trough on an adjacent band-like element.
摘要翻译：公开了一种包括多个间隔开的带状元件和相交连接件的可径向扩张的支架。带状元件具有大致蛇形结构，以向每个带状元件提供大致正弦曲线的连续波。波的特征在于沿着圆柱体大致纵向方向的多个峰和谷，使得当支架从第一直径扩展到第二直径时，带状元件中的波浪打开。交叉连接件基本上为U形并终止在第一和第二柄部中。链节的第一柄从带状元件上的峰和谷之间的区域发出，并且链节的第二柄从相邻带状元件上的峰和谷之间的区域发出。

9. 发明申请

US20110166642A1 Stent Configurations 有权
标题翻译：支架配置
公开(公告)号：US20110166642A1
公开(公告)日：2011-07-07
申请号：US13048474
申请日：2011-03-15
申请人： Timothy G. J. Ehr , Graig L. Kveen
发明人： Timothy G. J. Ehr , Graig L. Kveen
IPC分类号： A61F2/82
CPC分类号： A61F2/91 , A61F2/915 , A61F2002/91525 , A61F2002/91533 , A61F2002/91541 , A61F2002/9155 , A61F2002/91558 , A61F2002/91583 , A61F2230/0054
摘要： The invention is directed to an expandable stent which is longitudinally flexible in both the unexpanded and expanded conditions. The stent includes spiral structures which at least partially unwind upon expansion of the stent to limit stent recoil. Regions of low strain in the stent during expansion are provided by the spiral structures.
摘要翻译：本发明涉及一种在未膨胀和膨胀的条件下纵向柔性的可扩张支架。支架包括螺旋结构，其在支架膨胀时至少部分退绕以限制支架反冲。在扩张期间支架中的低应变区域由螺旋结构提供。

10. 发明授权

US07442203B2 Stent configurations 有权
标题翻译：支架配置
公开(公告)号：US07442203B2
公开(公告)日：2008-10-28
申请号：US10321089
申请日：2002-12-17
申请人： Timothy G. J. Ehr , Graig L. Kveen
发明人： Timothy G. J. Ehr , Graig L. Kveen
IPC分类号： A61F2/06
CPC分类号： A61F2/915 , A61F2/91 , A61F2002/91525 , A61F2002/91541 , A61F2002/91558
摘要： Improved stent configurations exhibiting limited recoil, resistance to compression and improved longitudinal flexibility are disclosed. The stent comprised of a plurality of annular elements aligned to form a cylindrical stent body. The annular elements are comprised of a plurality of open, generally boomerang-shaped segments interconnected top-to-bottom around each of the annular elements. Adjacent annular elements are interconnected by interconnecting element.
摘要翻译：公开了改进的展示有限的反冲，抗压缩性和改进的纵向柔性的支架结构。所述支架由多个环形元件组成，所述环形元件对准以形成圆柱形支架体。环形元件由围绕每个环形元件的顶部到底部相互连接的多个开放的，一般为回旋形的形状的段组成。相邻的环形元件通过互连元件相互连接。

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