专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

2. 发明授权

US5643929A 1,2,4-oxidiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents 失效
标题翻译： 1,2,4-氧化噻吩基 - 苯氧基烷基异恶唑及其作为抗病毒剂的用途
公开(公告)号：US5643929A
公开(公告)日：1997-07-01
申请号：US444795
申请日：1995-05-19
申请人： Guy Dominic Diana , Theodore John Nitz
发明人： Guy Dominic Diana , Theodore John Nitz
IPC分类号： A61K31/42 , A61K31/422 , A61K31/4245 , A61P31/12 , C07D413/12 , C07D413/14 , A01K31/41
CPC分类号： C07D413/10 , C07D413/12 , C07D413/14
摘要： Compounds of the formula ##STR1## wherein: R.sub.1 is alkyl, alkoxy, hydroxy, cycloalkyl, hydroxyalkyl, alkoxyalkyl, hydroxyalkoxy, alkylthioalkyl, alkylsulfinylalkyl, alkylsulfonylalkyl, aminoalkyl, alkylaminoalkyl, dialkylaminoalkyl, alkoxycarbonyl, carboxy, or cyanomethyl;Y is alkylene of 3 to 9 carbon atoms,R.sub.2 and R.sub.3 independently are hydrogen, alkyl, alkoxy, halo, cyano, trifluoromethyl and nitro;R.sub.4 is alkoxy, hydroxy, halomethyl, dihalomethyl, trihalomethyl, dihaloethyl, cycloalkyl, heterocyclyl, alkoxycarbonyl, hydroxyalkyl, alkoxyalkyl, alkanecarbonyloxyalkyl, cyano, halo, thioalkyl, alkylthioalkyl, alkylthio, thio, 2,2,2-trifluoro-ethyl, (4-methylphenyl)sulfonyloxymethyl, N=Q or CON=Q, where N=Q is amino, alkylamino or dialkylamino;R.sub.5 is hydrogen or halo or alkyl.
摘要翻译：其中：R1是烷基，烷氧基，羟基，环烷基，羟基烷基，烷氧基烷基，羟基烷氧基，烷基硫代烷基，烷基亚磺酰基烷基，烷基磺酰基烷基，氨基烷基，烷基氨基烷基，二烷基氨基烷基，烷氧基羰基，羧基或氰基甲基。 Y是3至9个碳原子的亚烷基，R2和R3独立地是氢，烷基，烷氧基，卤素，氰基，三氟甲基和硝基; R4是烷氧基，羟基，卤代甲基，二卤代甲基，三卤代甲基，二卤代乙基，环烷基，杂环基，烷氧基羰基，羟基烷基，烷氧基烷基，烷基羰氧基烷基，氰基，卤素，硫代烷基，烷基硫代烷基，烷硫基，硫代，2,2,2-三氟乙基，（4 - 甲基苯基）磺酰氧基甲基，N = Q或CON = Q，其中N = Q是氨基，烷基氨基或二烷基氨基; R5是氢或卤素或烷基。

IPRDB

热门服务

关于我们

友情链接

联系方式