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1. 发明申请

WO2020051288A1 CONVERTER HAVING A TRANSFORMER WITH SECONDARY CENTRAL POINT TAP 审中-公开
公开(公告)号：WO2020051288A1
公开(公告)日：2020-03-12
申请号：PCT/US2019/049679
申请日：2019-09-05
申请人： THE UNIVERSITY OF TEXAS AT AUSTIN
发明人： HUANG, Alex Q.
IPC分类号： H02M5/257 , H02J3/18 , H02M5/14 , H02M3/335
摘要： A method and apparatus include a primary transformer coil, a secondary transformer coil, and a center tapped inductor coupled to the secondary transformer coil. A first switch may be in electrical communication with the center tapped inductor and may be configured to affect the first output voltage. A second switch may be in electrical communication with the center tapped inductor and may be configured to affect the second output voltage. In a particular example with an analog current (AC) output voltage, the two output voltages are out of phase to each other. In a direct current (DC) implementation, the transformer may be operated to output a positive and a negative output voltage. The apparatus may function as a resonant converter, or may operate in non-resonant mode. In one implementation, an H bridge may provide reactive power support. An inductor filter may be in electrical communication with the secondary transformer coil. Where desired, a diode bridge may be in electrical communication with the primary transformer coil.

2. 发明申请

WO2012161823A1 NERVE COAPTATION APPARATUS 审中-公开
标题翻译：神经科技设备
公开(公告)号：WO2012161823A1
公开(公告)日：2012-11-29
申请号：PCT/US2012/026764
申请日：2012-02-27
申请人： THE GENERAL HOSPITAL CORPORATION d/b/a MASSACHUSETTS GENERAL HOSPITAL , THE UNIVERSITY OF TEXAS AT AUSTIN , WINOGRAD, Jonathan M. , KEATING, Cameron P. , OMOBONO, Mark , BITTNER, George D. , GONZALEZ-LIMA, Francisco , ZUZEK, Aleksej , FAN, Jerry
发明人： WINOGRAD, Jonathan M. , KEATING, Cameron P. , OMOBONO, Mark , BITTNER, George D. , GONZALEZ-LIMA, Francisco , ZUZEK, Aleksej , FAN, Jerry
IPC分类号： A61B17/11
CPC分类号： A61B17/1128 , A61B2017/00893 , A61B2017/1132 , A61M5/00
摘要： An apparatus for coaptation of first and second severed nerve segments. The apparatus includes a plurality of nerve-engaging features or coupling members that each connect to another coupling member to form coupling pairs. The coupling pairs are advantageously movable relative to each other to permit nerve swelling, inhibit nerve compression, and facilitate delivery of pharmaceutical agents.
摘要翻译：一种用于第一和第二切断神经节段接合的装置。该装置包括多个神经接合特征或联接构件，每个连接构件连接到另一联接构件以形成联接对。耦合对有利地相对于彼此移动以允许神经肿胀，抑制神经压迫，并且便于药剂的递送。

3. 发明申请

WO2011100753A2 INTERVENTIONAL PHOTOACOUSTIC IMAGING SYSTEM 审中-公开
标题翻译：传统摄影成像系统
公开(公告)号：WO2011100753A2
公开(公告)日：2011-08-18
申请号：PCT/US2011/024917
申请日：2011-02-15
申请人： THE JOHNS HOPKINS UNIVERSITY , BOCTOR, Emad , KANG, Jin , EMELIANOV, Stanislav , KARPIOUK, Andrei , THE UNIVERSITY OF TEXAS AT AUSTIN
发明人： BOCTOR, Emad , KANG, Jin , EMELIANOV, Stanislav , KARPIOUK, Andrei
IPC分类号： A61N7/00 , A61B8/12
CPC分类号： A61B5/0095 , A61B5/4331 , A61B5/4381 , A61B5/6848 , A61B5/6852 , A61B5/7225 , A61B8/08 , A61B8/0841 , A61B10/0233 , A61B18/00 , A61B18/1477 , A61B18/1485 , A61B18/20 , A61B18/24 , A61B90/11 , A61B2017/4225 , A61B2018/2005 , A61B2090/378 , A61N5/1001 , A61N5/1007 , A61N5/1027 , A61N2005/1058
摘要： An interventional photoacoustic imaging system and method for cancer treatment comprises an optical source for applying laser energy to optically excite a treatment area, a needle, ablation tool or catheter for inserting the optical source into a body of a patient adjacent the treatment area, and an ultrasonic transducer for detecting the acoustic waves. A processor receives the raw data from the ultrasound system and processes it to thereby form a photoacoustic image of the tissue in real time. As such, image formation may be performed preoperatively, intraoperatively, and postoperatively.
摘要翻译：用于癌症治疗的介入性光声成像系统和方法包括用于施加激光能量以光学激发治疗区域的光源，用于将光源插入邻近治疗区域的患者体内的针，消融工具或导管，以及用于检测声波的超声换能器。处理器从超声系统接收原始数据并对其进行处理，从而实时地形成组织的光声像。因此，可以在手术前，术中和术后进行图像形成。

4. 发明申请

WO2005123937A2 METHODS FOR EXPRESSING RNP PARTICLES IN EUKARYOTIC CELLS 审中-公开
标题翻译：用于在核细胞中表达RNP颗粒的方法
公开(公告)号：WO2005123937A2
公开(公告)日：2005-12-29
申请号：PCT/US2005/020893
申请日：2005-06-14
申请人： THE UNIVERSITY OF TEXAS AT AUSTIN , CUI, Xiaoxia , LAMBOWITZ, Alan , SALDANHA, Roland
发明人： CUI, Xiaoxia , LAMBOWITZ, Alan , SALDANHA, Roland
IPC分类号： C12P21/06
CPC分类号： C12N15/63 , C12N15/85
摘要： Provided herein are nucleic acid constructs and methods for producing or enhancing the production of group II intron RNP particles in eukaryotic cells. The present methods comprise introducing at least one nucleic acid construct comprising a nucleic acid encoding a modified or wild type group II intron RNA and a wild-type or modified group II intron-encoded protein into the eukaryotic cell, and maintaining the cell under conditions that allow for expression of the group II intron RNA and the group II intron-encoded protein in the cell. The nucleic acid encoding the group II intron RNA is operably linked to an RNA polymerase I, an RNA polymerase II, or an RNA polymerase III promoter, and the nucleic acid encoding the group II intron-encoded protein is operably linked to an RNA polymerase II promoter. In certain embodiments, a subcellular localization signal is attached to the group II intron-encoded protein.
摘要翻译：本文提供了核酸构建体和用于在真核细胞中产生或增强II组内含子RNP颗粒的生产的方法。本发明的方法包括将包含编码经修饰或野生型II组内含子RNA的核酸和野生型或修饰II型内含子编码蛋白质的至少一种核酸构建体引入真核细胞中，并将细胞维持在允许在细胞中表达II组内含子RNA和II组内含子编码的蛋白质。编码II组内含子RNA的核酸可操作地连接到RNA聚合酶I，RNA聚合酶II或RNA聚合酶III启动子，编码II组内含子编码蛋白的核酸可操作地连接到RNA聚合酶II 子。在某些实施方案中，将亚细胞定位信号连接到II组内含子编码的蛋白质。

5. 发明申请

WO2005123962A3 GENE TARGETING IN EUKARYOTIC CELLS BY GROUP II INTRON RIBONUCLEOPROTEIN PARTICLES 审中-公开
公开(公告)号：WO2005123962A3
公开(公告)日：2005-12-29
申请号：PCT/US2005/020894
申请日：2005-06-14
申请人： THE UNIVERSITY OF TEXAS AT AUSTIN , CUI, Xiaoxia , LAMBOWITZ, Alan , VERNON, Jamie, L. , WATANBE, Kazuo
发明人： CUI, Xiaoxia , LAMBOWITZ, Alan , VERNON, Jamie, L. , WATANBE, Kazuo
IPC分类号： C12N15/85
摘要： Provided herein are methods of disrupting DNA substrates in eukaryotic cells and methods of introducing exogenous polynucleotides into target sites in the DNA substrates In certain embodiments the methods comprise introducing a purified group II intron ribonucleoprotein (RNP) particle into the host cell. In certain embodiments the method comprises introducing a group II intron RNP particle and a DNA construct comprising an exogenous polynucleotide flanked by sequences that are homologous to sequences that flank the target site in the endogenous DNA substrate. In certain embodiments, the methods also involve introducing magnesium ions into the eukaryotic cells.

6. 发明申请

WO2020051285A1 LATERAL SEMICONDUCTOR DEVICE AND METHOD OF MANUFACTURE 审中-公开
公开(公告)号：WO2020051285A1
公开(公告)日：2020-03-12
申请号：PCT/US2019/049672
申请日：2019-09-05
申请人： THE UNIVERSITY OF TEXAS AT AUSTIN
发明人： HUANG, Alex Q.
IPC分类号： H01L29/10 , H01L29/872 , H01L29/08 , H01L29/40 , H01L29/423 , H01L29/78
摘要： A method and apparatus include an n-doped layer having a first applied charge, and a p - -doped layer having a second applied charge. The p - -doped layer may be positioned below the n-doped layer. A p + -doped buffer layer may have a third applied charge and be positioned below the p - -doped layer. The respective charges at each layer may be determined based on a dopant level and a physical dimension of the layer. In one example, the n-doped layer, the p - -doped layer, and the p + -doped buffer layer comprise a lateral semiconductor manufactured from silicon carbide (SiC).

7. 发明申请

WO2019217577A1 MODULAR HIGH STEP-DOWN DC/DC CONVERTER 审中-公开
公开(公告)号：WO2019217577A1
公开(公告)日：2019-11-14
申请号：PCT/US2019/031357
申请日：2019-05-08
申请人： THE UNIVERSITY OF TEXAS AT AUSTIN
发明人： HUANG, Alex , HUANG, Qingyun
IPC分类号： H02M3/158
摘要： Method and apparatus include a circuit having a duty cycle and interleaving modulation configured to realize high density and efficient energy transfer. The circuit may efficiently achieve higher step-down voltage ratios with fewer electrical components. For example, as few as seven electrical devices, such as switches and diodes, may be used to realize at least a four-to-one conversion ratio. The high density of the circuit is advantageous to meet shrinking space demands. A modulator may interleave signals sent to the electrical components (e.g., switching devices via driver circuitry). The driver signals may include a duty cycle of l/(nc+l), where nc is (n-l)/3, and n is the number of devices.

8. 发明申请

WO2006102615A2 CRASH PREDICTION NETWORK WITH GRADED WARNING FOR VEHICLE 审中-公开
标题翻译：用于车辆的等级警告的冲击预测网络
公开(公告)号：WO2006102615A2
公开(公告)日：2006-09-28
申请号：PCT/US2006/010888
申请日：2006-03-23
申请人： TOYOTA TECHNICAL CENTER USA, INC. , THE UNIVERSITY OF TEXAS AT AUSTIN , SHERONY, Rini , MIKKULAINEN, Risto, P. , STANLEY, Kenneth, O. , KOHL, Nathaniel, F.
发明人： SHERONY, Rini , MIKKULAINEN, Risto, P. , STANLEY, Kenneth, O. , KOHL, Nathaniel, F.
IPC分类号： B60R22/00
CPC分类号： G08G1/165 , B60R21/013 , B60W40/09 , B60W50/14 , B60W2050/0057
摘要： A method for facilitating the avoidance of a vehicle collision with an object includes the following steps: a) providing a neural network, b) evolving a good driver, c) evolving a crash predictor, and d) outputting a graded warning signal.
摘要翻译：一种便于避免车辆与物体碰撞的方法包括以下步骤：a）提供神经网络，b）演进好的驾驶员，c）演变碰撞预测器，以及d）输出分级警告信号。

9. 发明申请

WO2021081290A1 METHOD FOR PLUGGING AND ABANDONING OIL AND GAS WELLS 审中-公开
公开(公告)号：WO2021081290A1
公开(公告)日：2021-04-29
申请号：PCT/US2020/056999
申请日：2020-10-23
申请人： BOARD OF REGENTS, THE UNIVERSITY OF TEXAS AT AUSTIN , PQ CORPORATION
发明人： VAN OORT, Eric , MCDONALD, Michael
IPC分类号： E21B33/13 , C09K8/42
摘要： A method and agent to induce accelerated creep deformation of shale rock formations in the annular gap between a shale formation and non-cemented sections of a casing string have been developed. A fluid containing alkali silicate or a modified alkali silicate is added to the annular space between the shale rock formation and the casing string. The alkali silicate promotes creep deformation of the shale rock, effectively closing the annulus surrounding the casing. It has been found lithium silicate provides the strongest shale-casing bond and is the presently preferred material for closing abandoned wells.

10. 发明申请

WO2019113649A1 METAL ORGANIC FRAMEWORK MEMBRANES 审中-公开
公开(公告)号：WO2019113649A1
公开(公告)日：2019-06-20
申请号：PCT/AU2018/051341
申请日：2018-12-14
申请人： MONASH UNIVERSITY , COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION , THE UNIVERSITY OF TEXAS AT AUSTIN
发明人： WANG, Huanting , ZHANG, Huacheng , LI, Xingya , LU, Jun , FREEMAN, Benny , HILL, Anita Joyce
IPC分类号： B01D61/44 , B01D67/00 , B01D69/02 , B01J20/22
摘要： Disclosed herein is an ion selective separation membrane including:a metal organic framework layer formed on, in, and/or around a substrate, the metal organic framework having a crystal structure that includes a first surface and a second surface and includes ion transport channels formed between respective pore windows in the first surface and the second surface;first and second electrodes to apply a potential difference across the membrane;wherein the respective pore windows have a pore size that is less than the hydrated diameter of the ion for which the ion selective separation membrane is selective.

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