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1. 发明授权

US08672783B2 Sports ball 有权
标题翻译：运动球
公开(公告)号：US08672783B2
公开(公告)日：2014-03-18
申请号：US13407979
申请日：2012-02-29
申请人： Takashi Fujikura , Masanobu Morishige , Shuzo Matsuno
发明人： Takashi Fujikura , Masanobu Morishige , Shuzo Matsuno
IPC分类号： A63B41/08
CPC分类号： A63B41/08 , A63B2243/0025 , A63B2243/0033 , A63B2243/0095
摘要： Surface panels of a sports ball are arranged to facilitate bending of their outer peripheral edge portions into an arc, without reducing strength of an elastic member, to define a groove at a seam between adjacent panels. Panels are adhered through the elastic members to a body defining a ball core with high adhesion strength. The panels have sheet material backed by an elastic member, each panel having an arched portion formed by bending inwardly an outer peripheral edge portion of each panel with a radius of curvature more than the thickness of the panel, after formation of many apertures in an inner peripheral edge portion of the elastic member. Lower edges of the arched portions of adjacent panels abut each other. A groove is defined at seams between adjacent panels, and the panels are adhered to a ball core body by adhering the elastic members to the body.
摘要翻译：运动球的表面面板布置成便于其外围边缘部分弯曲成弧形，而不会降低弹性构件的强度，以在相邻面板之间的接缝处限定凹槽。面板通过弹性构件粘附到限定具有高粘合强度的球芯的主体。这些面板具有由弹性构件支撑的片材，每个面板具有拱形部分，该拱形部分通过在每个面板的外周边缘部分的内部弯曲大于面板的厚度，在内部形成许多孔之后向内弯曲弹性构件的周边部分。相邻板的拱形部分的下边缘彼此邻接。在相邻面板之间的接缝处限定凹槽，并且通过将弹性构件粘附到身体而将面板粘附到球芯体。

2. 发明申请

US20130021674A1 ZOOM LENS AND IMAGE PICKUP APPARATUS USING THE SAME 有权
标题翻译：使用相同的变焦镜头和图像拾取装置
公开(公告)号：US20130021674A1
公开(公告)日：2013-01-24
申请号：US13542002
申请日：2012-07-05
申请人： Takashi FUJIKURA
发明人： Takashi FUJIKURA
IPC分类号： G02B15/14
CPC分类号： G02B15/173
摘要： A zoom lens includes, in order from the object side, a positive first lens group, a negative second lens group, a positive third lens group, a positive fourth lens group, a negative fifth lens group, and a positive sixth lens group. The first lens group, the third lens group, and the sixth lens group are fixed. The second lens group, fourth lens group, and the fifth lens group are movable. The first lens group includes a reflecting optical element that bends the optical path. The second lens group includes a negative lens and a cemented lens made up of a negative lens and a positive lens. The third lens group includes an aperture stop. The fourth lens group includes a positive lens and a negative lens. The fifth lens group includes a negative lens.
摘要翻译：变焦透镜从物体侧依次包括正的第一透镜组，负的第二透镜组，正的第三透镜组，正的第四透镜组，负的第五透镜组和正的第六透镜组。第一透镜组，第三透镜组和第六透镜组是固定的。第二透镜组，第四透镜组和第五透镜组是可移动的。第一透镜组包括弯曲光路的反射光学元件。第二透镜组包括负透镜和由负透镜和正透镜构成的胶合透镜。第三透镜组包括孔径光阑。第四透镜组包括正透镜和负透镜。第五透镜组包括负透镜。

3. 发明授权

US5391825A Sulfamoyl substituted phenethylamine intermediates 失效
标题翻译：磺酰基取代的苯乙胺中间体
公开(公告)号：US5391825A
公开(公告)日：1995-02-21
申请号：US174608
申请日：1993-12-28
申请人： Kunihiro Niigata , Takashi Fujikura
发明人： Kunihiro Niigata , Takashi Fujikura
IPC分类号： A61K31/18 , C07C311/16 , C07C311/24 , C07C317/14 , C07D203/10
CPC分类号： C07D203/10 , C07C309/00
摘要： Pharmaceutical compositions are provided for the treatment of disorders in a subject, such as hypertension, congestive heart failure, angina pectoris, lower urinary tract dysfunction and prostatic hypertrophy. The compositions when administered to a subject produce an .alpha.-adrenergic blocking action and contain as an active ingredient sulfamoyl-substituted phenethylamine derivatives, such as optically active 5-2-[2-(2-ethoxyphenoxy)ethylamino]-2-methylethyl-2-methoxybenzenesulfonamide, and a pharmaceutically acceptable carrier.
摘要翻译：提供药物组合物用于治疗受试者中的疾病，例如高血压，充血性心力衰竭，心绞痛，下尿路功能障碍和前列腺肥大。给予受试者时的组合物产生α-肾上腺素能阻断作用并含有作为活性成分的氨磺酰基取代的苯乙胺衍生物，例如光学活性的5-2- [2-（2-乙氧基苯氧基）乙基氨基] -2-甲基乙基-2 - 甲氧基苯磺酰胺和药学上可接受的载体。

4. 发明授权

US5378849A Substituted tetrahydroisoquinoline compounds, and process for producing them, and composition containing them 失效
标题翻译：取代的四氢异喹啉化合物及其制备方法和含有它们的组合物
公开(公告)号：US5378849A
公开(公告)日：1995-01-03
申请号：US981137
申请日：1992-11-24
申请人： Akihiro Tanaka , Takashi Fujikura , Ryuji Tsuzuki , Masaki Yokota , Takeyuki Yatsu
发明人： Akihiro Tanaka , Takashi Fujikura , Ryuji Tsuzuki , Masaki Yokota , Takeyuki Yatsu
IPC分类号： C07D217/16 , C07D495/04 , C07D513/04 , C07D471/02 , C07D217/00
CPC分类号： C07D495/04 , C07D217/16 , C07D513/04
摘要： This invention provides certain novel substituted tetrahydroisoquinoline opticulisomers of the formula: ##STR1## wherein A represents the formula ##STR2## wherein R is hydrogen or halogen; R.sup.1 is hydrogen, lower alkyl, hydroxyl, halogen, amino, or lower acylamino;R.sup.2 is hydrogen, lower alkyl, hydroxyl, amino, or lower alkylsulfonylamino;R.sup.3 is hydrogen, lower alkyl, or hydroxyl;R.sup.4 is a hydrogen atom or a lower alkylsulfonyl;with the proviso that when R.sup.1 is hydroxyl, R.sup.2 and R.sup.3 are all not hydrogen, or salts thereof.
摘要翻译：本发明提供了一些具有下式的新型取代的四氢异喹啉视觉异构体：其中+ E，crc / A /代表式其中R是氢或卤素; R1是氢，低级烷基，羟基，卤素，氨基或低级酰基氨基; R2是氢，低级烷基，羟基，氨基或低级烷基磺酰基氨基; R3是氢，低级烷基或羟基; R4是氢原子或低级烷基磺酰基; 条件是当R 1是羟基时，R 2和R 3都不是氢或其盐。

5. 发明授权

US5079256A Substituted tetrahydroisoquinoline compounds and method containing them 失效
标题翻译：取代的四氢喹啉化合物和含有它们的方法
公开(公告)号：US5079256A
公开(公告)日：1992-01-07
申请号：US412840
申请日：1989-09-26
申请人： Akihiro Tanaka , Takashi Fujikura , Ryuji Tsuzuki , Masaki Yokota , Takeyuki Yatsu
发明人： Akihiro Tanaka , Takashi Fujikura , Ryuji Tsuzuki , Masaki Yokota , Takeyuki Yatsu
IPC分类号： C07D217/16 , C07D277/44 , C07D495/04 , C07D513/04
CPC分类号： C07D495/04 , C07D217/16 , C07D513/04
摘要： A compound of the formula (I) or its salt and a process for producing the compounds. The compounds have the effect of dilating neophrovascular tracts; ##STR1## wherein ##STR2## represents the formula ##STR3## wherein R.sup.4 is a hydrogen atom or lower alkylsulfonyl;R.sup.1 is hydrogen, lower alkyl, hydroxyl, halogen, amino, or lower acylamino;R.sup.2 is hydrogen, lower alkyl, hydroxyl, amino, or lower alkylsulfonylamino;R.sup.3 is hydrogen, lower alkyl, or hydroxyl;R is hydrogen or halogen;with the proviso that when R.sup.1 is hydroxyl, there is no case that all of R.sup.2, R.sup.3 and R are hydrogens, and further with the proviso that when R is hydrogen, A excludes ##STR4## or a salt thereof.

6. 发明授权

US4904660A Histidine derivatives as superior renin inhibitors 失效
标题翻译：组氨酸衍生物作为优良的肾素抑制剂
公开(公告)号：US4904660A
公开(公告)日：1990-02-27
申请号：US160173
申请日：1988-02-25
申请人： Kohji Nakano , Takashi Fujikura , Ryuichiro Hara , Masato Ichihara , Yukiko Fukunaga , Masayuki Shibasaki
发明人： Kohji Nakano , Takashi Fujikura , Ryuichiro Hara , Masato Ichihara , Yukiko Fukunaga , Masayuki Shibasaki
IPC分类号： A61K38/00 , C07D233/54 , C07D403/12 , C07D405/12 , C07D405/14 , C07D409/12 , C07D417/12 , C07K5/02 , C07K5/065
CPC分类号： C07D233/64 , C07D403/12 , C07D405/12 , C07D405/14 , C07D409/12 , C07D417/12 , C07K5/0227 , C07K5/06078 , A61K38/00 , Y10S530/86
摘要： Novel compounds of the following formula (I) and their salts: A compound of the formula (I) ##STR1## These compounds are expected to be useful for renin inhibitors. Thus, the compounds are useful medical agents, in particular, anti-hypertensive agents.

7. 发明授权

US4880841A Process of producing phenethylamine derivatives 失效
标题翻译：生产苯乙胺衍生物的方法
公开(公告)号：US4880841A
公开(公告)日：1989-11-14
申请号：US307200
申请日：1989-02-03
申请人： Kazuo Imai , Kunihiro Niigata , Takashi Fujikura , Shinichi Hashimoto , Toichi Takenaka , Kazuo Honda
发明人： Kazuo Imai , Kunihiro Niigata , Takashi Fujikura , Shinichi Hashimoto , Toichi Takenaka , Kazuo Honda
IPC分类号： A61K20060101 , A61K31/135 , A61K31/255
CPC分类号： A61K31/135 , A61K31/255
摘要： Phenethylamine derivatives shown by the general formula ##STR1## wherein Ro represents a lower alkyl group; R.sub.1 represents a lower alkyl group or a lower alkoxy group; R.sub.2 represents hydrogen atom or a hydroxyl group; R.sub.3 and R.sub.4 each represents hydrogen atom or a lower alkyl group; R.sub.5 represents hydrogen atom or a lower alkoxy group; X represents oxygen atom or a methylene group; m is an integer of 1 -3; and n is an integer of 0-2 and the acid addition salts thereof.These compounds exhibit a strong .alpha.-adreneregic blocking action and are useful as an antihypertensive agent.
摘要翻译：苯乙胺衍生物，其通式为：其中R a代表低级烷基; R1表示低级烷基或低级烷氧基; R2表示氢原子或羟基; R3和R4各自表示氢原子或低级烷基; R5表示氢原子或低级烷氧基; X表示氧原子或亚甲基; m为1-3的整数; n为0-2的整数，及其酸加成盐。这些化合物表现出强烈的α肾上腺素能阻断作用，可用作抗高血压药。

8. 发明授权

US4703063A Sulfamoyl substituted phenethylamine derivatives and process of producing them 失效
标题翻译：磺酰胺取代的苯乙胺衍生物及其制备方法
公开(公告)号：US4703063A
公开(公告)日：1987-10-27
申请号：US756790
申请日：1985-07-18
申请人： Kazuo Imai , Kunihiro Niigata , Takashi Fujikura , Shinichi Hashimoto , Toichi Takenaka
发明人： Kazuo Imai , Kunihiro Niigata , Takashi Fujikura , Shinichi Hashimoto , Toichi Takenaka
IPC分类号： A61K31/18 , A61K31/205 , A61K31/255 , A61P9/04 , A61P9/12 , C07C67/00 , C07C301/00 , C07C303/40 , C07C311/15 , C07C311/16 , C07C311/29 , C07C311/37 , C07C317/00 , C07D203/10 , C07C143/78 , C07C143/80
CPC分类号： C07D203/10 , C07C309/00
摘要： Novel sulfamoyl-substituted phenethylamine derivatives which exhibit .alpha.-adrenergic blocking action and are useful as an antihypertensive agent and an agent for the treatment of congestive heart failure.

9. 发明授权

US4217305A Phenylethanolamine derivatives 失效
标题翻译：苯乙醇胺衍生物
公开(公告)号：US4217305A
公开(公告)日：1980-08-12
申请号：US946192
申请日：1978-09-27
申请人： Kazuo Imai , Kunihiro Niigata , Takashi Fujikura , Shinichi Hashimoto , Toichi Takenaka
发明人： Kazuo Imai , Kunihiro Niigata , Takashi Fujikura , Shinichi Hashimoto , Toichi Takenaka
IPC分类号： C07C311/37 , A61K31/137 , A61P9/12 , C07C43/23 , C07C317/32 , C07C323/67 , C07D303/34 , C07D317/64 , C07D319/20 , C07C143/78 , A61K31/18 , A61K31/335 , C07D319/18
CPC分类号： C07D317/64 , C07C43/23 , C07D303/34 , C07D319/20
摘要： Novel phenylethanolamine derivatives represented by the formula ##STR1## wherein R represents a hydrogen atom, a halogen atom, a hydroxyl group, a lower alkyl group, a lower alkoxy group, a lower alkylthio group, an amino group, a lower acylamino group, a lower alkylsulfonyl group, or a lower alkylsulfonylamino group; R.sub.1, R.sub.2, R.sub.3 and R.sub.4, which may be the same or different, each represents hydrogen or a lower alkyl group; R.sub.5 represents an aryl group which may have a substituent, a benzodioxane ring group which may have a substituent, an aryloxy group which may have a substituent, or an arylthio group which may have a substituent; said R.sub.5 being, however, a benzodioxane ring group which may have a substituent, an aryloxy group which may have a substituent, or an arylthio group which may have a substituent when R is a hydroxyl group; and n represents 0 or an integer of 1-3 and the acid addition salts thereof.The compounds of this invention exhibit .alpha.- and .beta.-adrenergic blocking actions and are useful as antihypertensive agents.
摘要翻译：其中R表示氢原子，卤素原子，羟基，低级烷基，低级烷氧基，低级烷硫基，氨基，低级酰氨基，低级烷基氨基，低级烷基磺酰基或低级烷基磺酰基氨基; R 1，R 2，R 3和R 4可以相同或不同，各自表示氢或低级烷基; R5表示可以具有取代基的芳基，可以具有取代基的苯并二恶烷环基，可以具有取代基的芳氧基或可以具有取代基的芳硫基; 然而，R 5表示可以具有取代基的苯并二恶烷环基，可以具有取代基的芳氧基或当R为羟基时可具有取代基的芳硫基; n表示0或1-3的整数，以及其酸加成盐。本发明的化合物显示出α-和β-肾上腺素能阻断作用并且可用作抗高血压药。

10. 发明授权

US4210751A Process for producing 7.beta.-amino-7.alpha.-methoxycephalosporins 失效
标题翻译：制备7种β-氨基-7α-甲氧基头孢菌素的方法
公开(公告)号：US4210751A
公开(公告)日：1980-07-01
申请号：US930214
申请日：1978-08-02
申请人： Kazuharu Tamazawa , Takashi Fujikura , Tadao Kojima , Masaru Iwanami
发明人： Kazuharu Tamazawa , Takashi Fujikura , Tadao Kojima , Masaru Iwanami
IPC分类号： C07D501/04 , C07D501/18 , C07D501/36 , C07D501/57
CPC分类号： C07D501/18 , C07D501/57
摘要： Process for producing 7.beta.-amino-7.alpha.-methoxycephalosporins without the epimerization or formation of the corresponding 7.alpha.-amino-7.beta.-methoxy isomers by deacylating cephalosporin derivatives having 7.beta.-acylamino-7.alpha.-methoxy group.
摘要翻译：通过脱酰基具有7个β-酰基氨基-7α-甲氧基的头孢菌素衍生物，生产7个β-氨基-7α-甲氧基头孢菌素而没有差向异构化或形成相应的7个α-氨基-7β-甲氧基异构体的方法。

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