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1. 发明授权

US08754112B2 Sulfone derivative 有权
标题翻译：砜衍生物
公开(公告)号：US08754112B2
公开(公告)日：2014-06-17
申请号：US13388218
申请日：2010-08-04
申请人： Shigeo Yamanoi , Hidenori Namiki , Takahiro Katagiri , Mayuko Akiu , Katsuji Kagechika , Takeshi Honda , Koji Matsumoto , Ryutaro Nakashima
发明人： Shigeo Yamanoi , Hidenori Namiki , Takahiro Katagiri , Mayuko Akiu , Katsuji Kagechika , Takeshi Honda , Koji Matsumoto , Ryutaro Nakashima
IPC分类号： A61K31/4245 , C07D271/06
CPC分类号： C07D271/06 , A61K31/4245 , A61K31/4439 , C07D413/12 , C07D413/14
摘要： Provided are a compound having an excellent hypoglycemic action, or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition having an excellent therapeutic effect and/or prophylactic effect on type 1 diabetes, type 2 diabetes, and the like, which cause an increase in the blood sugar level due to abnormal sugar metabolism. A compound represented by general formula (I), or a pharmaceutically acceptable salt thereof, is disclosed.
摘要翻译：提供具有优异的降血糖作用的化合物或其药学上可接受的盐，以及对1型糖尿病，2型糖尿病等具有优异的治疗效果和/或预防效果的药物组合物，其引起增加血糖水平由于糖代谢异常。公开了由通式（I）表示的化合物或其药学上可接受的盐。

2. 发明授权

US08722711B2 Acylbenzene derivative 有权
标题翻译：酰基苯衍生物
公开(公告)号：US08722711B2
公开(公告)日：2014-05-13
申请号：US13879076
申请日：2011-10-13
申请人： Shigeo Yamanoi , Takahiro Katagiri , Hidenori Namiki , Madoka Hatta , Koji Matsumoto , Kanako Takahashi , Tomomi Yoshitomi , Yuichi Ochiai
发明人： Shigeo Yamanoi , Takahiro Katagiri , Hidenori Namiki , Madoka Hatta , Koji Matsumoto , Kanako Takahashi , Tomomi Yoshitomi , Yuichi Ochiai
IPC分类号： A61K31/4245 , C07D271/06
CPC分类号： C07D271/06 , A61K31/4245
摘要： Provided are compounds having an excellent hypoglycemic action and a β cell- or pancreas-protecting action or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition having an excellent therapeutic effect and/or prophylactic effect on type 1 diabetes, type 2 diabetes, and the like, which cause an increase in the blood sugar level due to abnormal sugar metabolism. A compound represented by general formula (I), or a pharmaceutically acceptable salt thereof, is disclosed.
摘要翻译：提供具有优异的降血糖作用和重要的化合物细胞或胰腺保护作用或其药学上可接受的盐，以及对1型糖尿病，2型糖尿病等具有优异的治疗效果和/或预防效果的药物组合物，其导致血糖水平升高由于糖代谢异常。公开了由通式（I）表示的化合物或其药学上可接受的盐。

3. 发明申请

US20120129832A1 AMIDE DERIVATIVE 有权
公开(公告)号：US20120129832A1
公开(公告)日：2012-05-24
申请号：US13388210
申请日：2010-08-04
申请人： Shigeo Yamanoi , Hidenori Namiki , Takahiro Katagiri , Mayuko Akiu , Katsuji Kagechika , Takeshi Honda , Koji Matsumoto , Ryutaro Nakashima
发明人： Shigeo Yamanoi , Hidenori Namiki , Takahiro Katagiri , Mayuko Akiu , Katsuji Kagechika , Takeshi Honda , Koji Matsumoto , Ryutaro Nakashima
IPC分类号： A61K31/5377 , C07D413/12 , A61P1/18 , A61P3/10 , A61P3/04 , C07D413/14 , A61K31/4245
CPC分类号： C07D413/12 , C07D271/06 , C07D413/14
摘要： Provided are a compound having an excellent hypoglycemic action, or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition having an excellent therapeutic effect and/or prophylactic effect on type 1 diabetes, type 2 diabetes, and the like, which cause an increase in the blood sugar level due to abnormal sugar metabolism. A compound represented by general formula (I), or a pharmaceutically acceptable salt thereof, is disclosed.
摘要翻译：提供具有优异的降血糖作用的化合物或其药学上可接受的盐，以及对1型糖尿病，2型糖尿病等具有优异的治疗效果和/或预防效果的药物组合物，其引起增加血糖水平由于糖代谢异常。公开了由通式（I）表示的化合物或其药学上可接受的盐。

4. 发明授权

US08557802B2 Amide derivative 有权
标题翻译：酰胺衍生物
公开(公告)号：US08557802B2
公开(公告)日：2013-10-15
申请号：US13388210
申请日：2010-08-04
申请人： Shigeo Yamanoi , Hidenori Namiki , Takahiro Katagiri , Mayuko Akiu , Katsuji Kagechika , Takeshi Honda , Koji Matsumoto , Ryutaro Nakashima
发明人： Shigeo Yamanoi , Hidenori Namiki , Takahiro Katagiri , Mayuko Akiu , Katsuji Kagechika , Takeshi Honda , Koji Matsumoto , Ryutaro Nakashima
IPC分类号： A61K31/4245 , C07D413/10 , C07D413/12 , C07D413/14
CPC分类号： C07D413/12 , C07D271/06 , C07D413/14
摘要： Provided are a compound having an excellent hypoglycemic action, or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition having an excellent therapeutic effect and/or prophylactic effect on type 1 diabetes, type 2 diabetes, and the like, which cause an increase in the blood sugar level due to abnormal sugar metabolism. A compound represented by general formula (I), or a pharmaceutically acceptable salt thereof, is disclosed.
摘要翻译：提供具有优异的降血糖作用的化合物或其药学上可接受的盐，以及对1型糖尿病，2型糖尿病等具有优异的治疗效果和/或预防效果的药物组合物，其引起增加血糖水平由于糖代谢异常。公开了由通式（I）表示的化合物或其药学上可接受的盐。

5. 发明申请

US20130217733A1 ACYLBENZENE DERIVATIVE 有权
标题翻译：苯乙烯衍生物
公开(公告)号：US20130217733A1
公开(公告)日：2013-08-22
申请号：US13879076
申请日：2011-10-13
申请人： Shigeo Yamanoi , Takahiro Katagiri , Hidenori Namiki , Madoka Hatta , Koji Matsumoto , Kanako Takahashi , Tomomi Yoshitomi , Yuichi Ochiai
发明人： Shigeo Yamanoi , Takahiro Katagiri , Hidenori Namiki , Madoka Hatta , Koji Matsumoto , Kanako Takahashi , Tomomi Yoshitomi , Yuichi Ochiai
IPC分类号： C07D271/06
CPC分类号： C07D271/06 , A61K31/4245
摘要： Provided are compounds having an excellent hypoglycemic action and a β cell- or pancreas-protecting action or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition having an excellent therapeutic effect and/or prophylactic effect on type 1 diabetes, type 2 diabetes, and the like, which cause an increase in the blood sugar level due to abnormal sugar metabolism. A compound represented by general formula (I), or a pharmaceutically acceptable salt thereof, is disclosed.
摘要翻译：提供具有优异的降血糖作用和β细胞或胰腺保护作用的化合物或其药学上可接受的盐，以及对1型糖尿病，2型糖尿病具有优异的治疗效果和/或预防效果的药物组合物，因为糖代谢异常导致血糖水平升高。公开了由通式（I）表示的化合物或其药学上可接受的盐。

6. 发明申请

US20080176399A1 METALLIC SILICIDE FORMING METHOD AND METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE 审中-公开
标题翻译：金属硅化物形成方法和制造半导体器件的方法
公开(公告)号：US20080176399A1
公开(公告)日：2008-07-24
申请号：US11671589
申请日：2007-02-06
申请人： Takahiro Katagiri , Yasunori Sogoh
发明人： Takahiro Katagiri , Yasunori Sogoh
IPC分类号： H01L21/44
CPC分类号： H01L21/28518 , H01L21/28052 , H01L29/665 , H01L29/6659 , H01L29/7833
摘要： A metallic silicide forms method of forming a metallic silicide layer on a semiconductor region containing silicon. The method includes the steps of: forming a first metal layer containing a first metal on the semiconductor region; forming a second metal layer containing a second metal on the semiconductor region to cover the first metal layer formed in the step of forming a first metal layer; and siliciding the semiconductor region with at least one of the first metal layer and the second metal layer by performing a heat treatment for the semiconductor region in which the second metal layer is formed to cover the first metal layer in the step of forming a second metal layer, forming the metallic silicide layer. The first metal layer is formed at a first temperature to be silicided. The second metal layer is formed at a second temperature lower than the first temperature.
摘要翻译：金属硅化物形成在含硅的半导体区域上形成金属硅化物层的方法。该方法包括以下步骤：在半导体区域上形成含有第一金属的第一金属层; 在半导体区域上形成含有第二金属的第二金属层，以覆盖在形成第一金属层的步骤中形成的第一金属层; 以及通过在形成第二金属的步骤中对形成有第二金属层以覆盖第一金属层的半导体区进行热处理，使半导体区域与第一金属层和第二金属层中的至少一个硅化，层，形成金属硅化物层。在第一温度下形成第一金属层以进行硅化处理。第二金属层在比第一温度低的第二温度下形成。

7. 发明申请

US20120129891A1 SULFONE DERIVATIVE 有权
公开(公告)号：US20120129891A1
公开(公告)日：2012-05-24
申请号：US13388218
申请日：2010-08-04
申请人： Shigeo Yamanoi , Hidenori Namiki , Takahiro Katagiri , Mayuko Akiu , Katsuji Kagechika , Takeshi Honda , Koji Matsumoto , Ryutaro Nakashima
发明人： Shigeo Yamanoi , Hidenori Namiki , Takahiro Katagiri , Mayuko Akiu , Katsuji Kagechika , Takeshi Honda , Koji Matsumoto , Ryutaro Nakashima
IPC分类号： A61K31/4439 , A61K31/4245 , A61P1/18 , A61P3/10 , A61P3/04 , C07D413/12 , C07D413/14
CPC分类号： C07D271/06 , A61K31/4245 , A61K31/4439 , C07D413/12 , C07D413/14
摘要： Provided are a compound having an excellent hypoglycemic action, or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition having an excellent therapeutic effect and/or prophylactic effect on type 1 diabetes, type 2 diabetes, and the like, which cause an increase in the blood sugar level due to abnormal sugar metabolism. A compound represented by general formula (I), or a pharmaceutically acceptable salt thereof, is disclosed.
摘要翻译：提供具有优异的降血糖作用的化合物或其药学上可接受的盐，以及对1型糖尿病，2型糖尿病等具有优异的治疗效果和/或预防效果的药物组合物，其引起增加血糖水平由于糖代谢异常。公开了由通式（I）表示的化合物或其药学上可接受的盐。

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