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1. 发明申请

US20130041135A1 FILLER FOR AFFINITY CHROMATOGRAPHY AND METHOD FOR ISOLATING IMMUNOGLOBULIN 有权
标题翻译：亲和色谱填充剂和分离免疫球蛋白的方法
公开(公告)号：US20130041135A1
公开(公告)日：2013-02-14
申请号：US13636410
申请日：2011-03-23
申请人： Kouji Tamori , Tetsuo Fukuta , Masaaki Miyaji , Yong Wang , Takayoshi Abe , Yusuke Okano , Masaki Momiyama , Takahiro Kawai
发明人： Kouji Tamori , Tetsuo Fukuta , Masaaki Miyaji , Yong Wang , Takayoshi Abe , Yusuke Okano , Masaki Momiyama , Takahiro Kawai
IPC分类号： C07K17/02 , C07K1/22
CPC分类号： C07K1/22 , B01D15/3804 , B01J20/286 , B01J20/288 , B01J20/3219 , B01J20/3274 , C07K2317/10
摘要： Provided are a filler for affinity chromatography which has excellent alkali resistance, and a method for isolating immunoglobulin. The filler for affinity chromatography is a filler in which a protein represented by the following formula (1) is immobilized on a carrier. R—R2 (1) wherein R represents an amino acid sequence consisting of 4 to 300 amino acid residues containing a region consisting of 4 to 20 contiguous histidine residues; and R2 represents an amino acid sequence capable of binding to immunoglobulin, the amino acid sequence consisting of 50 to 500 amino acid residues containing Z domain of Protein A or a fragment thereof, or a variant thereof, provided that the R binds to C-terminus or N-terminus of the R2.
摘要翻译：提供了具有优异的耐碱性的亲和色谱法的填充剂和分离免疫球蛋白的方法。用于亲和层析的填料是其中由下式（1）表示的蛋白质固定在载体上的填料。 R-R2（1）其中R表示由4至300个氨基酸残基组成的氨基酸序列，其含有由4至20个连续组氨酸残基组成的区域; 并且R 2表示能够结合免疫球蛋白的氨基酸序列，所述氨基酸序列由含有蛋白A的Z结构域或其片段的50至500个氨基酸残基或其变体组成，条件是R与C-末端结合或R2的N-末端。

2. 发明申请

US20080160277A1 MAGNETIC PARTICLES, METHOD FOR PRODUCING SAME, AND BIOCHEMICAL CARRIER 审中-公开
标题翻译：磁性颗粒，其生产方法和生物化学载体
公开(公告)号：US20080160277A1
公开(公告)日：2008-07-03
申请号：US11961562
申请日：2007-12-20
申请人： Kouji Tamori , Eiji Takamoto , Takahiro Kawai
发明人： Kouji Tamori , Eiji Takamoto , Takahiro Kawai
IPC分类号： B32B27/14 , H01F1/00
CPC分类号： C01G49/0018 , B82Y25/00 , C01G49/0027 , C01G49/06 , C01G49/08 , C01G51/00 , C01G53/00 , C01P2004/03 , C01P2004/51 , C01P2004/61 , C01P2004/62 , C01P2004/80 , C01P2004/84 , C01P2006/42 , C09C3/12 , H01F1/0054 , H01F1/36
摘要： Magnetic particles comprise magnetic mother particles (A) having a particle diameter of d and non-magnetic child particles (B) having a particle diameter of d/2 or less stacked on the surface of the magnetic mother particles (A).
摘要翻译：磁性粒子包含具有粒径d的磁性母体颗粒（A）和堆积在磁性母体颗粒（A）的表面上的粒径为d / 2或更小的非磁性子颗粒（B）。

3. 发明授权

US06363514B1 Sound reproducing system and method capable of decoding audio data even in case of failure of detecting syncword 失效
标题翻译：即使在检测到同步字失败的情况下也能够对音频数据进行解码的声音再现系统和方法
公开(公告)号：US06363514B1
公开(公告)日：2002-03-26
申请号：US09225345
申请日：1999-01-05
申请人： Takahiro Kawai , Chuya Hayashi
发明人： Takahiro Kawai , Chuya Hayashi
IPC分类号： H03M1333
CPC分类号： G11B20/10527 , G11B20/1252 , G11B20/1806 , G11B27/10 , G11B27/3027
摘要： A sound reproducing system that decodes audio data in a frame with which detection of a syncword fails, if a syncword included in a subsequent frame is detected, if correctness of bit stream information in the subsequent frame is proved, and if no CRC error is detected (when CRC is included). This makes it possible to solve a problem involved in a conventional system in that when a unit frame without an error check pattern is input and a synchronization detector produces a synchronization detection error signal, unpleasant sound interruption can take place even if the audio data is correct, because the correctness of the audio data cannot be checked, and hence the audio data cannot be decoded in this case.
摘要翻译：如果检测到后续帧中包括的同步字，则如果检测到后续帧中的比特流信息的正确性，并且如果没有检测到CRC错误，则解码同步字的检测失败的帧中的音频数据的声音再现系统（包括CRC时）。这使得可以解决常规系统中涉及的问题，即当没有错误检查图案的单位帧被输入并且同步检测器产生同步检测误差信号时，即使音频数据是正确的也可能发生不愉快的声音中断，因为音频数据的正确性不能被检查，因此在这种情况下音频数据不能被解码。

4. 发明授权

US5200253A Hologram forming sheet and process for producing the same 失效
标题翻译： HOLOGRAM成型片及其制造方法
公开(公告)号：US5200253A
公开(公告)日：1993-04-06
申请号：US562316
申请日：1990-08-03
申请人： Masahisa Yamaguchi , Hitoshi Fujii , Shuichi Kobayashi , Takahiro Kawai
发明人： Masahisa Yamaguchi , Hitoshi Fujii , Shuichi Kobayashi , Takahiro Kawai
IPC分类号： B29C43/22 , B32B27/08 , B44F1/08 , G03H1/02
CPC分类号： B44F1/08 , B29C43/222 , B32B27/08 , G03H1/0252 , G03H1/028 , B29K2023/06 , B29K2023/086 , B29K2023/12 , B29K2067/00 , B29K2077/00 , G03H1/0236 , G03H2001/187 , G03H2250/10 , G03H2250/12 , G03H2250/36 , G03H2250/40 , G03H2270/12 , Y10S428/915 , Y10S428/916 , Y10T428/24802 , Y10T428/24843 , Y10T428/31993
摘要： A thin film of molten polypropylene resin extruded from a T die is pressed and cooled with a chill roll equipped with a hologram relief master plate on its peripheral surface, whereupon a hologram pattern is simultaneously formed as an integral part of the polypropylene resin sheet being molded. Since the polypropylene resin has a Rockwell hardness of at least 70, the hologram pattern formed in the resulting hologram forming sheet is less likely to be damaged or lost during subsequent processing.
摘要翻译：将从T模头挤出的熔融聚丙烯树脂薄膜在其外周表面上用装备有全息图浮雕原版的冷却辊进行压制和冷却，随后全息图同时形成为模塑的聚丙烯树脂片的组成部分。由于聚丙烯树脂的洛氏硬度至少为70，所以在随后的加工中，形成的全息图形成片中的全息图不太可能被损坏或损失。

5. 发明授权

US5301294A Address bus control system 失效
标题翻译：地址总线控制系统
公开(公告)号：US5301294A
公开(公告)日：1994-04-05
申请号：US689556
申请日：1991-04-23
申请人： Takahiro Kawai , Masatsugu Shinozaki , Hitoshi Sadamitsu , Tadashi Kyoda , Katsuya Takanashi , Hironori Uchida
发明人： Takahiro Kawai , Masatsugu Shinozaki , Hitoshi Sadamitsu , Tadashi Kyoda , Katsuya Takanashi , Hironori Uchida
IPC分类号： G06F13/14 , G06F12/02 , G06F12/06
CPC分类号： G06F12/0223 , G06F12/0661
摘要： An address bus control system is provided of the type in which a controller including a central processing unit is connected through an address bus and a data bus to hardware modules which control equipment to be controlled. An address space defined by an address bus includes a discrimination space for discriminating the attribute of the hardware module and a function space for allocating and clearing an address space for a function interface of the hardware module. The attribute of a hardware module connected to a connector having a corresponding address is recognized using the discrimination space. The function interface of each hardware module is assigned a space within the function space in accordance with the contents of the discrimination space in concern, or the assigned space is canceled. An address of the function space can be allocated to only a necessary function interface, merely by connecting the hardware module to the connector, allowing to set up hardware modules equal to or larger than the total address space.
摘要翻译：提供地址总线控制系统，其中包括中央处理单元的控制器通过地址总线和数据总线连接到控制要控制的设备的硬件模块。由地址总线定义的地址空间包括用于识别硬件模块的属性的鉴别空间和用于分配和清除硬件模块的功能接口的地址空间的功能空间。使用识别空间来识别连接到具有相应地址的连接器的硬件模块的属性。每个硬件模块的功能接口根据关注的鉴别空间的内容在功能空间内分配一个空间，或者分配的空间被取消。仅通过将硬件模块连接到连接器，可以将功能空间的地址分配给必要的功能接口，允许设置等于或大于总地址空间的硬件模块。

6. 发明申请

US20110262748A1 PACKING MATERIAL FOR AFFINITY CHROMATOGRAPHY 有权
标题翻译：包装材料的亲和色谱
公开(公告)号：US20110262748A1
公开(公告)日：2011-10-27
申请号：US13121124
申请日：2009-09-24
申请人： Kouji Tamori , Tetsuo Fukuta , Masaaki Miyaji , Yong Wang , Takayoshi Abe , Yuusuke Okano , Masaki Momiyama , Takahiro Kawai
发明人： Kouji Tamori , Tetsuo Fukuta , Masaaki Miyaji , Yong Wang , Takayoshi Abe , Yuusuke Okano , Masaki Momiyama , Takahiro Kawai
IPC分类号： B01D15/38 , C08F24/00
CPC分类号： C07K1/22 , B01J20/286 , B01J20/321 , B01J20/3219 , B01J20/3274 , Y10T428/29
摘要： An affinity chromatography packing material includes porous mother particles that include a copolymer of a monomer mixture including a crosslinkable vinyl monomer and an epoxy group-containing vinyl monomer, a ligand being bound to the porous mother particles, and the porous mother particles including a ring-opening epoxy group produced by ring-opening of the epoxy group included in the porous mother particles.
摘要翻译：亲和层析填充材料包括多孔母体颗粒，其包括包含可交联乙烯基单体和含环氧基的乙烯基单体的单体混合物的共聚物，与多孔母体颗粒结合的配体，以及多孔母体颗粒，开环环氧基，其由包含在多孔母体颗粒中的环氧基开环制得。

7. 发明申请

US20110233454A1 ORGANIC POLYMER PARTICLES AND PROCESS FOR PRODUCING SAME 审中-公开
标题翻译：有机聚合物颗粒及其生产方法
公开(公告)号：US20110233454A1
公开(公告)日：2011-09-29
申请号：US13152802
申请日：2011-06-03
申请人： Kouji TAMORI , Eiji TAKAMOTO , Takahiro KAWAI
发明人： Kouji TAMORI , Eiji TAKAMOTO , Takahiro KAWAI
IPC分类号： C08F222/16 , H01F1/36
CPC分类号： C08G63/181 , C08G63/199 , C08G63/52 , Y10T428/2991 , Y10T428/2998
摘要： Organic polymer particles having a structure shown by the following formula (1) are disclosed. wherein A represents an alkylidene group, an alkylene group, a cyclohexylene group, or a phenylene group, and B represents a linear or branched alkylene group or an alkylidene group having 1 to 6 carbon atoms.
摘要翻译：公开了具有下式（1）所示结构的有机聚合物颗粒。其中A表示亚烷基，亚烷基，亚环己基或亚苯基，B表示直链或支链亚烷基或碳原子数1〜6的亚烷基。

8. 发明授权

US07981512B2 Organic polymer-magnetic particles and process for producing same 有权
标题翻译：有机聚合物 - 磁性颗粒及其制备方法
公开(公告)号：US07981512B2
公开(公告)日：2011-07-19
申请号：US11773801
申请日：2007-07-05
申请人： Kouji Tamori , Eiji Takamoto , Takahiro Kawai
发明人： Kouji Tamori , Eiji Takamoto , Takahiro Kawai
IPC分类号： B32B5/16
CPC分类号： C08G63/181 , C08G63/199 , C08G63/52 , Y10T428/2991 , Y10T428/2998
摘要： Organic polymer particles having a structure shown by the following formula (1) are disclosed. wherein A represents an alkylidene group, an alkylene group, a cyclohexylene group, or a phenylene group, and B represents a linear or branched alkylene group or an alkylidene group having 1 to 6 carbon atoms.
摘要翻译：公开了具有下式（1）所示结构的有机聚合物颗粒。其中A表示亚烷基，亚烷基，亚环己基或亚苯基，B表示直链或支链亚烷基或碳原子数1〜6的亚烷基。

9. 发明授权

US08846877B2 Packing material for affinity chromatography 有权
标题翻译：亲和层析的包装材料
公开(公告)号：US08846877B2
公开(公告)日：2014-09-30
申请号：US13121124
申请日：2009-09-24
申请人： Kouji Tamori , Tetsuo Fukuta , Masaaki Miyaji , Yong Wang , Takayoshi Abe , Yuusuke Okano , Masaki Momiyama , Takahiro Kawai
发明人： Kouji Tamori , Tetsuo Fukuta , Masaaki Miyaji , Yong Wang , Takayoshi Abe , Yuusuke Okano , Masaki Momiyama , Takahiro Kawai
IPC分类号： C07K1/14 , G01N33/544 , G01N33/547 , B01J20/32 , C07K1/22 , B01J20/286
CPC分类号： C07K1/22 , B01J20/286 , B01J20/321 , B01J20/3219 , B01J20/3274 , Y10T428/29
摘要： An affinity chromatography packing material includes porous mother particles that include a copolymer of a monomer mixture including a crosslinkable vinyl monomer and an epoxy group-containing vinyl monomer, a ligand being bound to the porous mother particles, and the porous mother particles including a ring-opening epoxy group produced by ring-opening of the epoxy group included in the porous mother particles.
摘要翻译：亲和层析填充材料包括多孔母体颗粒，其包括包含可交联乙烯基单体和含环氧基的乙烯基单体的单体混合物的共聚物，与多孔母体颗粒结合的配体，以及多孔母体颗粒，开环环氧基，其由包含在多孔母体颗粒中的环氧基开环制得。

10. 发明申请

US20100022755A1 PLATELET AGGREGATION INDUCING SUBSTANCE 有权
标题翻译： PLATELET聚集诱导物质
公开(公告)号：US20100022755A1
公开(公告)日：2010-01-28
申请号：US12520508
申请日：2007-12-12
申请人： Yasuto Umeda , Shinichi Takasaki , Takafumi Takebayashi , Takahiro Kawai
发明人： Yasuto Umeda , Shinichi Takasaki , Takafumi Takebayashi , Takahiro Kawai
IPC分类号： C07K14/745
CPC分类号： C07K14/001 , C07K14/78 , Y10T428/2982
摘要： A platelet aggregation inducing substance containing as an active ingredient a polypeptide having a peptide fragment represented by formula (1) (component A): -(Pro-X-Gly)n- (1) wherein X represents Pro or Hyp; and n represents an integer of from 20 to 5,000.
摘要翻译：含有作为活性成分的具有式（1）表示的肽片段（成分A）的多肽的血小板聚集诱导物质： - （Pro-X-Gly）n-（1）其中X表示Pro或Hyp; n表示20〜5000的整数。

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