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1. 发明申请

WO2009003049A2 SELF-EXPANDING PROSTHESIS 审中-公开
标题翻译：自我展现
公开(公告)号：WO2009003049A2
公开(公告)日：2008-12-31
申请号：PCT/US2008/068210
申请日：2008-06-25
申请人： MICRO VENTION, INC. , TIEU, Tai, D. , GULACHENSKI, Joseph
发明人： TIEU, Tai, D. , GULACHENSKI, Joseph
IPC分类号： A61F2/94 , A61F2/82 , A61B18/04
CPC分类号： A61F2/86 , A61F2/95 , A61F2002/823 , A61F2210/0014 , A61F2210/0033
摘要： In one preferred embodiment, a prosthesis is provided that can be selectively expanded by increasing the temperature of the prosthesis within the patient. The prosthesis is composed of a shape memory material that expands when heated to a temperature greater than an average body temperature, allowing the user to selectively heat and therefore expand the prosthesis at a desired location.
摘要翻译：在一个优选实施例中，提供了可以通过增加患者体内的假体的温度来选择性地扩张的假体。假体由形状记忆材料组成，当被加热到大于平均体温的温度时，该形状记忆材料膨胀，允许使用者选择性地加热并因此使假体在期望的位置膨胀。

2. 发明申请

WO2004082523A8 MITRAL VALVE REPAIR SYSTEM 审中-公开
标题翻译：麻醉阀维修系统
公开(公告)号：WO2004082523A8
公开(公告)日：2005-07-21
申请号：PCT/US2004007383
申请日：2004-03-11
申请人： EDWARDS LIFESCIENCES CORP , ZARBATANY DAVID , TIEU TAI , PUNG PONAKA , VIDELL JOSEPH , PERRY KENNETH E , KRUMME JOHN , BUCHBINDER MAURICE
发明人： ZARBATANY DAVID , TIEU TAI , PUNG PONAKA , VIDELL JOSEPH , PERRY KENNETH E , KRUMME JOHN , BUCHBINDER MAURICE
IPC分类号： A61B17/00 , A61B17/04 , A61B17/22 , A61B17/30 , A61F2/24 , A61B17/068 , A61B17/064
CPC分类号： A61B17/0469 , A61B17/0467 , A61B17/0482 , A61B17/0487 , A61B2017/00243 , A61B2017/00371 , A61B2017/00783 , A61B2017/0445 , A61B2017/0451 , A61B2017/0464 , A61B2017/0472 , A61B2017/0488 , A61B2017/22052 , A61B2017/22069 , A61B2017/306 , A61F2/2442
摘要： A mitral valve repair system comprises a guide catheter having a proximal end, a distal end, and at least one internal lumen formed therein, a therapy catheter capable of applying a suture to the tissue, and a fastener catheter capable of attaching a fastener to the suture. The therapy catheter and the fastener catheter are capable of traversing the internal lumen of the guide catheter. The mitral valve is repaired by advancing the catheter through the guide catheter, stabilizing a first leaflet with the therapy catheter, deploying a first suture into the stabilized first leaflet, disengaging the first leaflet from the therapy catheter while leaving the first suture attached thereto, stabilizing a second leaflet with the therapy catheter, deploying a second suture into the second leaflet, disengaging the second leaflet from the therapy catheter while leaving the second suture attached thereto, and joining the first and second leaflets by reducing the distance between the first and second sutures.
摘要翻译：二尖瓣修复系统包括具有近端，远端和形成在其中的至少一个内腔的导向导管，能够将缝合线施加到组织的治疗导管，以及能够将紧固件附接到缝合。治疗导管和紧固导管能够穿过引导导管的内腔。通过将导管推进通过引导导管来修复二尖瓣，通过治疗导管稳定第一传单，将第一缝合线部署到稳定化的第一传单中，使第一传单从治疗导管脱离，同时使第一缝合线附着于其上，稳定具有治疗导管的第二传单，将第二缝合线部署到第二传单中，使第二传单与治疗导管脱离接合，同时留下附接到其上的第二缝合线，以及通过减小第一和第二缝合线之间的距离来接合第一和第二小叶。

3. 发明申请

WO2004082523A3 MITRAL VALVE REPAIR SYSTEM 审中-公开
公开(公告)号：WO2004082523A3
公开(公告)日：2004-09-30
申请号：PCT/US2004/007383
申请日：2004-03-11
申请人： EDWARDS LIFESCIENCES CORPORATION , ZARBATANY, David , TIEU, Tai , PUNG, Ponaka , VIDELL, Joseph , PERRY, Kenneth, E. , KRUMME, John , BUCHBINDER, Maurice
发明人： ZARBATANY, David , TIEU, Tai , PUNG, Ponaka , VIDELL, Joseph , PERRY, Kenneth, E. , KRUMME, John , BUCHBINDER, Maurice
IPC分类号： A61B17/068
摘要： A mitral valve repair system comprises a guide catheter having a proximal end, a distal end, and at least one internal lumen formed therein, a therapy catheter capable of applying a suture to the tissue, and a fastener catheter capable of attaching a fastener to the suture. The therapy catheter and the fastener catheter are capable of traversing the internal lumen of the guide catheter. The mitral valve is repaired by advancing the catheter through the guide catheter, stabilizing a first leaflet with the therapy catheter, deploying a first suture into the stabilized first leaflet, disengaging the first leaflet from the therapy catheter while leaving the first suture attached thereto, stabilizing a second leaflet with the therapy catheter, deploying a second suture into the second leaflet, disengaging the second leaflet from the therapy catheter while leaving the second suture attached thereto, and joining the first and second leaflets by reducing the distance between the first and second sutures.

4. 发明申请

WO2013138789A1 STENT AND STENT DELIVERY DEVICE 审中-公开
公开(公告)号：WO2013138789A1
公开(公告)日：2013-09-19
申请号：PCT/US2013/032636
申请日：2013-03-15
申请人： MICROVENTION, INC. , VONG, Shirley , TSAI, Priscilla , LAM, Cang , SOLTANIAN, Ross , BAK-BOYCHUK, Greg , TIEU, Tai, D. , PUNG, Ponaka , TUASON, Arnold , GRIFFITH, Heather
发明人： VONG, Shirley , TSAI, Priscilla , LAM, Cang , SOLTANIAN, Ross , BAK-BOYCHUK, Greg , TIEU, Tai, D. , PUNG, Ponaka , TUASON, Arnold , GRIFFITH, Heather
IPC分类号： A61F2/06
CPC分类号： A61F2/852 , A61F2/844 , A61F2/885 , A61F2/90 , A61F2/966 , A61F2002/823 , A61F2002/9522 , A61F2002/9528 , A61F2002/9665 , A61F2210/0014 , A61F2210/0076 , A61F2230/0021 , A61F2230/005 , A61F2230/0058 , A61F2230/0067 , A61F2250/0018 , A61F2250/0023 , A61F2250/0039 , A61F2250/0098 , A61F2310/00131
摘要： In one embodiment according to the present invention, a stent is described having a generally cylindrical body formed from a single woven nitinol wire. The distal and proximal ends of the stent include a plurality of loops, some of which include marker members used for visualizing the position of the stent. In another embodiment, the previously described stent includes an inner flow diverting layer.
摘要翻译：在根据本发明的一个实施例中，描述了一种支架，其具有由单一编织的镍钛诺导线形成的大致圆柱形的主体。支架的远端和近端包括多个环，其中一些环包括用于可视化支架位置的标记构件。在另一个实施例中，前述的支架包括内部流动转向层。

5. 发明申请

WO2009086214A1 A SYSTEM AND METHOD OF DETECTING IMPLANT DETACHMENT 审中-公开
标题翻译：检测植入物分离的系统和方法
公开(公告)号：WO2009086214A1
公开(公告)日：2009-07-09
申请号：PCT/US2008/087855
申请日：2008-12-19
申请人： MICROVENTION, INC. , TIEU, Tai, D. , MARTINEZ, George
发明人： TIEU, Tai, D. , MARTINEZ, George
IPC分类号： A61F2/06
CPC分类号： A61F2/95 , A61F2002/9505 , A61F2250/0071 , G06Q30/0254 , G06Q30/0261
摘要： A system and method of detecting implant detachment within the body of a patient. The activation of the heater coil causes the degradation, melting or reduction of a component that brings the heater coil into or out of electrical contact with another component, or causes the individual loops of the coil to contact each other, thereby resulting in a notable change in resistance in the circuit supplying the heater coil with electricity.
摘要翻译：一种检测患者体内植入物分离的系统和方法。加热器线圈的激活导致使加热器线圈进入或者与另一部件电接触的部件的劣化，熔化或还原，或使线圈的各个环路彼此接触，从而导致显着变化在供电加热器线圈的电路中的电阻。

6. 发明申请

WO2007005579A1 SYSTEM, APPARATUS, AND METHOD FOR REPAIRING SEPTAL DEFECTS 审中-公开
标题翻译：系统，装置和修复缺陷缺陷的方法
公开(公告)号：WO2007005579A1
公开(公告)日：2007-01-11
申请号：PCT/US2006/025531
申请日：2006-06-28
申请人： EDWARDS LIFESCIENCES CORPORATION , ZARBATANY, David , TIEU, Tai
发明人： ZARBATANY, David , TIEU, Tai
IPC分类号： A61M1/00 , A61B17/00 , A61B17/04
CPC分类号： A61B17/0482 , A61B17/0057 , A61B17/0467 , A61B17/0487 , A61B2017/00243 , A61B2017/00575 , A61B2017/0445 , A61B2017/0451 , A61B2017/0464 , A61B2017/0472 , A61B2017/0488 , A61B2017/0496 , A61B2017/306
摘要： An apparatus and method for repairing septal defects includes advancing a catheter to the site of the defect, grasping opposing edges of the defect, passing one or more suture lines through the opposing edges, and tightening the suture lines. The catheter can include one or more vacuum ports, with the vacuum ports being sized and configured to grasp opposing edges of the defect when vacuum is applied thereto. The vacuum ports may be positioned longitudinally distant from each other along the catheter, and may also be on different sides of the catheter. The vacuum ports may have vacuum applied via independent control. The catheter can also include suture deploying structure that prevents the suture line from becoming entangled in the catheter.
摘要翻译：用于修复间隔缺损的装置和方法包括将导管推进到缺损部位，抓住缺损的相对边缘，使一条或多条缝合线穿过相对边缘，并收紧缝合线。导管可以包括一个或多个真空端口，其中真空端口的尺寸和构造被设计成当向其施加真空时抓住缺陷的相对边缘。真空端口可以沿着导管相对于彼此纵向定位，并且也可以在导管的不同侧面上。真空端口可以通过独立控制来施加真空。导管还可以包括防止缝合线缠结在导管中的缝线展开结构。

7. 发明申请

WO2012155093A1 DEVICE FOR OCCLUDING A LUMEN 审中-公开
标题翻译：用于监护一个灯的装置
公开(公告)号：WO2012155093A1
公开(公告)日：2012-11-15
申请号：PCT/US2012/037621
申请日：2012-05-11
申请人： MICROVENTION, INC. , FITZ, Matthew , TIEU, Tai, D. , O'LEARY, Shawn
发明人： FITZ, Matthew , TIEU, Tai, D. , O'LEARY, Shawn
IPC分类号： A61M29/00
CPC分类号： A61B17/12031 , A61B17/12109 , A61B17/1214 , A61B17/12172 , A61B17/12177 , A61B17/12181 , A61B17/1219
摘要： One embodiment according to the present invention includes an occlusion device in which the support structure or frame expands circumferentially within the lumen to secure an expansile plug or embolic material. Once in place, the expansile plug or embolic material expands, thereby occluding the target lumen. Another embodiment according to the present invention includes a radially expandable support structure having a closed portion for capturing subsequently delivered embolic material, such as embolic coils. For example, the structure may have a closed portion at its distal end or at its middle (forming an hourglass shape). Additionally, the closed portion may be formed from the support structure itself or from a discrete, second layer that is attached within the support structure.
摘要翻译：根据本发明的一个实施例包括闭塞装置，其中支撑结构或框架在腔内周向膨胀以固定膨胀塞子或栓塞材料。一旦就位，膨胀塞或栓塞物膨胀，从而封闭目标腔。根据本发明的另一实施例包括具有封闭部分的径向可扩张的支撑结构，用于捕获随后输送的栓塞材料，例如栓塞线圈。例如，该结构可以在其远端或其中部（形成沙漏形状）处具有封闭部分。此外，封闭部分可以由支撑结构本身形成，也可以由连接在支撑结构内的离散的第二层形成。

8. 发明申请

WO2010121049A1 IMPLANT DELIVERY SYSTEM 审中-公开
标题翻译：植物输送系统
公开(公告)号：WO2010121049A1
公开(公告)日：2010-10-21
申请号：PCT/US2010/031268
申请日：2010-04-15
申请人： MICROVENTION, INC. , TIEU, Tai D. , MORITA, Hideo , NGUYEN, Helen
发明人： TIEU, Tai D. , MORITA, Hideo , NGUYEN, Helen
IPC分类号： A61B19/00
CPC分类号： A61B17/12022 , A61B17/1214 , A61B2017/12054 , A61F2/2439 , A61F2/95 , A61F2/966 , A61F2002/30062 , A61F2002/9505 , A61F2002/9511 , A61F2210/0004
摘要： In one embodiment, the present invention relates to a mechanically releasable delivery system. More specifically, this embodiment includes an implantable device secured by tether at a distal end of the delivery system. The tether is fixed to the implantable device and looped around a selectively slidable mandrel. When the mandrel is retracted to expose its distal end, the looped tether slides off the mandrel, freeing the implantable device. Alternately, the tether can be fixed to the delivery system, wrapped around a portion of the implantable device and looped on to the slidable mandrel. Preferably, movement of the mandrel is controlled by an actuation control on the handle of the delivery system, allowing the user to selectively release the implantable device during a medical procedure.
摘要翻译：在一个实施方案中，本发明涉及机械可释放的递送系统。更具体地，该实施例包括通过系绳在输送系统的远端处固定的可植入装置。系绳固定在可植入装置上，环绕选择性滑动心轴。当心轴缩回以露出其远端时，环形系绳从心轴滑下，释放可植入装置。或者，系绳可以固定到递送系统，缠绕在可植入装置的一部分上并环绕到可滑动的心轴上。优选地，通过在输送系统的手柄上的致动控制来控制心轴的运动，允许使用者在医疗过程期间选择性地释放可植入装置。

9. 发明申请

WO2004082523A2 MITRAL VALVE REPAIR SYSTEM AND METHOD FOR USE 审中-公开
标题翻译：麻醉阀维修系统及使用方法
公开(公告)号：WO2004082523A2
公开(公告)日：2004-09-30
申请号：PCT/US2004007383
申请日：2004-03-11
申请人： EDWARDS LIFESCIENCES CORP , ZARBATANY DAVID , TIEU TAI , PUNG PONAKA , VIDELL JOSEPH , PERRY KENNETH E , KRUMME JOHN , BUCHBINDER MAURICE
发明人： ZARBATANY DAVID , TIEU TAI , PUNG PONAKA , VIDELL JOSEPH , PERRY KENNETH E , KRUMME JOHN , BUCHBINDER MAURICE
IPC分类号： A61B17/00 , A61B17/04 , A61B17/22 , A61B17/30 , A61F2/24 , A61F
CPC分类号： A61B17/0469 , A61B17/0467 , A61B17/0482 , A61B17/0487 , A61B2017/00243 , A61B2017/00371 , A61B2017/00783 , A61B2017/0445 , A61B2017/0451 , A61B2017/0464 , A61B2017/0472 , A61B2017/0488 , A61B2017/22052 , A61B2017/22069 , A61B2017/306 , A61F2/2442
摘要： The present invention is directed to various systems for repairing tissue within the heart of a patient. The mitral valve repair system of the present invention comprises a guide catheter having a proximal end, a distal end, and at least one internal lumen formed therein, a therapy catheter capable of applying a suture to the tissue, and a fastener catheter capable of attaching a fastener to the suture. The therapy catheter and the fastener catheter are capable of traversing the internal lumen of the guide catheter. In addition, the present invention discloses various methods for repairing tissue within the heart of the patient. In one embodiment, the method of repairing heart valve tissue includes advancing a guide catheter through a circulatory pathway to a location in the heart proximate to a heart valve, advancing a therapy catheter through the guide catheter to the heart valve, stabilizing a first leaflet with the therapy catheter, deploying a first suture into the stabilized first leaflet, disengaging the first leaflet from the therapy catheter while leaving the first suture attached thereto, stabilizing a second leaflet with the therapy catheter, deploying a second suture into the second leaflet, disengaging the second leaflet from the therapy catheter while leaving the second suture attached thereto, and joining the first and second leaflets by reducing the distance between the first and second sutures.
摘要翻译：本发明涉及用于修复患者心脏内的组织的各种系统。本发明的二尖瓣修复系统包括具有近端，远端和形成在其中的至少一个内腔的引导导管，能够将缝合线施加到组织上的治疗导管，以及能够附接紧固件到缝合线。治疗导管和紧固导管能够穿过引导导管的内腔。此外，本发明公开了用于修复患者心脏内的组织的各种方法。在一个实施例中，修复心脏瓣膜组织的方法包括使引导导管通过循环路径前进到靠近心脏瓣膜的心脏中的位置，将治疗导管通过引导导管推进到心脏瓣膜，使第一传单与所述治疗导管将第一缝合线部署到所述稳定化的第一小叶中，使所述第一传播带与所述治疗导管脱离接合，同时使所述第一缝合线附接到所述导管，使所述治疗导管稳定第二传播片，将第二缝合线部署到所述第二传单中，第二传单，同时离开附接到其上的第二缝合线，并且通过减小第一和第二缝合线之间的距离来接合第一和第二小叶。

10. 发明申请

WO2010121049A9 IMPLANT DELIVERY SYSTEM 审中-公开
标题翻译：植入物输送系统
公开(公告)号：WO2010121049A9
公开(公告)日：2010-12-02
申请号：PCT/US2010031268
申请日：2010-04-15
申请人： MICROVENTION INC , TIEU TAI D , MORITA HIDEO , NGUYEN HELEN
发明人： TIEU TAI D , MORITA HIDEO , NGUYEN HELEN
IPC分类号： A61B19/00
CPC分类号： A61B17/12022 , A61B17/1214 , A61B2017/12054 , A61F2/2439 , A61F2/95 , A61F2/966 , A61F2002/30062 , A61F2002/9505 , A61F2002/9511 , A61F2210/0004
摘要： In one embodiment, the present invention relates to a mechanically releasable delivery system. More specifically, this embodiment includes an implantable device secured by tether at a distal end of the delivery system. The tether is fixed to the implantable device and looped around a selectively slidable mandrel. When the mandrel is retracted to expose its distal end, the looped tether slides off the mandrel, freeing the implantable device. Alternately, the tether can be fixed to the delivery system, wrapped around a portion of the implantable device and looped on to the slidable mandrel. Preferably, movement of the mandrel is controlled by an actuation control on the handle of the delivery system, allowing the user to selectively release the implantable device during a medical procedure.
摘要翻译：在一个实施例中，本发明涉及一种机械可释放的输送系统。更具体地说，该实施例包括通过系绳在输送系统的远端处固定的可植入装置。系绳固定在可植入装置上并环绕可选择性滑动的心轴。当心轴缩回以暴露其远端时，环状绳索从心轴上滑下，释放可植入装置。可选地，系绳可以被固定到输送系统，缠绕在可植入装置的一部分周围并且环绕到可滑动心轴上。优选地，心轴的运动通过输送系统的手柄上的致动控制来控制，从而允许使用者在医疗程序期间选择性地释放可植入装置。

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