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1. 发明申请

WO2013038429A3 NOVEL SGLT INHIBITORS 审中-公开
标题翻译：新的SGLT抑制剂
公开(公告)号：WO2013038429A3
公开(公告)日：2013-11-28
申请号：PCT/IN2012000612
申请日：2012-09-12
申请人： PANACEA BIOTEC LTD , JAIN RAJESH , TREHAN SANJAY , DAS JAGATTARAN , NANDA GURMEET KAUR , THUNGATHURTHI SASTRY V R S , SINGH NISHAN , SHARMA SUDHIR KUMAR
发明人： JAIN RAJESH , TREHAN SANJAY , DAS JAGATTARAN , NANDA GURMEET KAUR , THUNGATHURTHI SASTRY V R S , SINGH NISHAN , SHARMA SUDHIR KUMAR
IPC分类号： A61P3/04 , A61P3/06 , A61P3/10
CPC分类号： C07D309/10 , C07D493/08 , C07H7/04
摘要： The present invention relates to novel compounds of Formula (I), their pharmaceutically acceptable derivatives, tautomeric forms, isomers, polymorphs, prodrugs, metabolites, salts or solvates thereof. The invention also relates to the processes for the synthesis of novel compounds of Formula (I), their pharmaceutically acceptable derivatives, tautomeric forms, isomers, polymorphs, prodrugs, metabolites, salts or solvates thereof. The present invention also provides pharmaceutical compositions comprising novel compounds of Formula (I) and methods of treating or preventing one or more conditions or diseases that may be regulated or normalized via inhibition of Sodium Glucose Cotransporter-2 (SGLT-2).
摘要翻译：本发明涉及式（I）的新化合物，其药学上可接受的衍生物，互变异构形式，异构体，多晶型物，前药，代谢物，盐或溶剂化物。本发明还涉及合成式（I）的新化合物，其药学上可接受的衍生物，互变异构形式，异构体，多晶型物，前药，代谢物，盐或溶剂合物的方法。本发明还提供了包含式（I）的新化合物的药物组合物以及治疗或预防可通过抑制葡萄糖协同转运蛋白-2（SGLT-2）而调节或正常化的一种或多种病症或疾病的方法。

2. 发明申请

WO2013038429A2 NOVEL SGLT INHIBITORS 审中-公开
标题翻译：新型SGLT抑制剂
公开(公告)号：WO2013038429A2
公开(公告)日：2013-03-21
申请号：PCT/IN2012/000612
申请日：2012-09-12
申请人： PANACEA BIOTEC LTD. , JAIN, Rajesh , TREHAN, Sanjay , DAS, Jagattaran , NANDA, Gurmeet, Kaur , THUNGATHURTHI, Sastry, V., R., S. , SINGH, Nishan , SHARMA, Sudhir, Kumar
发明人： JAIN, Rajesh , TREHAN, Sanjay , DAS, Jagattaran , NANDA, Gurmeet, Kaur , THUNGATHURTHI, Sastry, V., R., S. , SINGH, Nishan , SHARMA, Sudhir, Kumar
IPC分类号： A61K31/70
CPC分类号： C07D309/10 , C07D493/08 , C07H7/04
摘要： The present invention relates to novel compounds of Formula (I), their pharmaceutically acceptable derivatives, tautomeric forms, isomers, polymorphs, prodrugs, metabolites, salts or solvates thereof. The invention also relates to the processes for the synthesis of novel compounds of Formula (I), their pharmaceutically acceptable derivatives, tautomeric forms, isomers, polymorphs, prodrugs, metabolites, salts or solvates thereof. The present invention also provides pharmaceutical compositions comprising novel compounds of Formula (I) and methods of treating or preventing one or more conditions or diseases that may be regulated or normalized via inhibition of Sodium Glucose Cotransporter-2 (SGLT-2).
摘要翻译：本发明涉及式（I）的新化合物，其药学上可接受的衍生物，互变异构形式，异构体，多晶型物，前药，代谢物，盐或溶剂合物。本发明还涉及合成式（I）的新化合物，其药学上可接受的衍生物，互变异构形式，异构体，多晶型物，前药，代谢物，盐或溶剂合物的方法。本发明还提供包含式（I）的新型化合物和治疗或预防可通过抑制葡萄糖转运蛋白-2（SGLT-2）调节或归一化的一种或多种病症或疾病的药物组合物。

3. 发明申请

WO2012172566A2 NOVEL SGLT INHIBITORS 审中-公开
标题翻译：新型SGLT抑制剂
公开(公告)号：WO2012172566A2
公开(公告)日：2012-12-20
申请号：PCT/IN2012000416
申请日：2012-06-13
申请人： PANACEA BIOTEC LTD , JAIN RAJESH , TREHAN SANJAY , DAS JAGATTARAN , NANDA GURMEET KAUR , THUNGATHURTHI SASTRY V R S , SINGH NISHAN , SHARMA SUDHIR KUMAR
发明人： JAIN RAJESH , TREHAN SANJAY , DAS JAGATTARAN , NANDA GURMEET KAUR , THUNGATHURTHI SASTRY V R S , SINGH NISHAN , SHARMA SUDHIR KUMAR
IPC分类号： C07H15/203
CPC分类号： A61K31/7048 , A61K31/70 , C07D309/10 , C07D401/04 , C07D493/08 , C07H7/04 , C07H9/04 , C07H13/04 , C07H13/12 , C07H15/04 , C07H19/01
摘要： The present invention relates to novel compounds of Formula (I), their pharmaceutically acceptable derivatives, tautomeric forms, isomers, polymorphs, prodrugs, metabolites, salts or solvates thereof. The invention also relates to the processes for the synthesis of novel compounds of Formula (I), their pharmaceutically acceptable derivatives, tautomeric forms, isomers, polymorphs, prodrugs, metabolites, salts or solvates thereof. The present invention also provides pharmaceutical compositions comprising novel compounds of Formula (I) and methods of treating or preventing one or more conditions or diseases that may be regulated or normalized via inhibition of Sodium Glucose Cotransporter-2 (SGLT-2).
摘要翻译：本发明涉及式（I）的新化合物，其药学上可接受的衍生物，互变异构形式，异构体，多晶型物，前药，代谢物，盐或溶剂合物。本发明还涉及合成式（I）的新化合物，其药学上可接受的衍生物，互变异构形式，异构体，多晶型物，前药，代谢物，盐或溶剂合物的方法。本发明还提供包含式（I）的新型化合物和治疗或预防可通过抑制葡萄糖转运蛋白-2（SGLT-2）调节或归一化的一种或多种病症或疾病的药物组合物。

4. 发明申请

WO2011070592A2 NOVEL SUGAR DERIVATIVES 审中-公开
标题翻译：新糖衍生物
公开(公告)号：WO2011070592A2
公开(公告)日：2011-06-16
申请号：PCT/IN2010000796
申请日：2010-12-09
申请人： PANACEA BIOTEC LTD , JAIN RAJESH , TREHAN SANJAY , THUNGATHURTHI SASTRY V R S , NANDA GURMEET KAUR , DAS JAGATTARAN , MAGADI SITARAM KUMAR , SHARMA SUDHIR KUMAR
发明人： JAIN RAJESH , TREHAN SANJAY , THUNGATHURTHI SASTRY V R S , NANDA GURMEET KAUR , DAS JAGATTARAN , MAGADI SITARAM KUMAR , SHARMA SUDHIR KUMAR
CPC分类号： C07H15/04 , C07D309/10
摘要： The present invention relates to novel compounds of Formula (I), their pharmaceutically acceptable derivatives, analogs, tautomeric forms, isomers, polymorphs, prodrugs, metabolites, salts or solvates thereof. The invention also relates to the processes for the synthesis of novel compounds of Formula I, their pharmaceutically acceptable derivatives, analogs, tautomeric forms, isomers, polymorphs, prodrugs, metabolites, salts or solvates thereof. The present invention also provides pharmaceutical compositions comprising novel compounds of Formula I and methods of treating or preventing one or more conditions or diseases that may be regulated or normalized via inhibition of Sodium Glucose Cotransporter-2 (SGLT-2). The invention also relates to the use of compounds of Formula I, their pharmaceutically acceptable derivatives, analogs, tautomeric forms, isomers, polymorphs, prodrugs, metabolites, salts or solvates thereof, for the manufacture of a medicament for the prophylaxis, amelioration and/or treatment of conditions or diseases that may be regulated or normalized via inhibition of Sodium Glucose Cotransporter-2 (SGLT-2) and the related diseases, disorders and conditions, in a subject in need thereof.
摘要翻译：本发明涉及式（I）的新化合物，其药学上可接受的衍生物，类似物，互变异构形式，异构体，多晶型物，前药，代谢物，盐或溶剂合物。本发明还涉及合成式I的新化合物，其药学上可接受的衍生物，类似物，互变异构形式，异构体，多晶型物，前药，代谢物，盐或溶剂合物的方法。本发明还提供包含式I的新化合物和治疗或预防一种或多种可通过抑制葡萄糖转运蛋白-2（SGLT-2）调节或归一化的病症或疾病的药物组合物。本发明还涉及式I化合物，其药学上可接受的衍生物，类似物，互变异构体形式，异构体，多晶型物，前体药物，代谢物，盐或溶剂合物在制备用于预防和/或改善在有需要的受试者中通过抑制葡萄糖转运蛋白-2（SGLT-2）和相关疾病，病症和病症来调节或归一化的病症或疾病的治疗。

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