专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

2. 发明专利

CA2652960C METHODS OF SCREENING FOR TRPM4 MODULATORS OF INSULIN SECRETION 未知
公开(公告)号：CA2652960C
公开(公告)日：2016-08-23
申请号：CA2652960
申请日：2007-05-25
申请人： THE QUEEN'S MEDICAL CENTER
发明人： PENNER REINHOLD , FLEIG ANDREA
IPC分类号： C12Q1/02 , C12Q1/68 , G01N33/53 , G01N33/567
摘要： The invention relates to methods useful in identifying candidate agents that modulate insulin secretion from an insulin secreting cell, where such molecules modulate TRPM4 activity and expression in the insulin secreting cell.

3. 发明专利

ES2569411T3 Sistema de seguimiento de movimiento para imágenes adaptativas en tiempo real y espectroscopia 未知
公开(公告)号：ES2569411T3
公开(公告)日：2016-05-10
申请号：ES07777148
申请日：2007-05-18
申请人： THE QUEEN'S MEDICAL CENTER , THE UNIV OF HAWAII , MEDICAL COLLEGE WISCONSIN INC , UWM RES FOUND INC
发明人： ERNST THOMAS MICHAEL , ARMSTRONG BRIAN STEWART RANDALL , PRIETO THOMAS EDMUND
IPC分类号： A61B5/00 , A61B5/055 , A61B5/11 , A61B6/04 , G01R33/28 , G01R33/565 , G06K9/32 , G06K17/00 , G06T7/00
摘要： Sistema de seguimiento de movimiento para seguir el movimiento de un objeto ('P') en un volumen de escaneo ('V') de un escáner por Resonancia Magnética (120), comprendiendo el sistema: un marcador de orientación de objeto (30) conectado al objeto (P); y un detector (40) que detecta de manera repetida posturas del marcador de orientación de objeto (30), caracterizado por que: el marcador de orientación de objeto (30), tal como un Retroreflector de rejilla, está configurado para indicar una postura en seis grados de libertad, el detector (40) comprende una cámara que está instalada dentro de una parte de imán (20) del escáner (120); un ordenador de seguimiento de movimiento (50) está dispuesto para analizar posturas del marcador de orientación de objeto (30) a medida que son detectadas por el detector (40) para determinar el movimiento del objeto (P) entre las repetidas detecciones; y el ordenador de seguimiento de movimiento (50) está dispuesto para enviar información de seguimiento al escáner (120) para obtener imágenes mientras ajusta dinámicamente las imágenes para compensar el movimiento del objeto (P).

4. 发明授权

US09867549B2 Motion tracking system for real time adaptive imaging and spectroscopy 有权
公开(公告)号：US09867549B2
公开(公告)日：2018-01-16
申请号：US14828299
申请日：2015-08-17
申请人： THE QUEEN'S MEDICAL CENTER , THE UNIVERSITY OF HAWAII , THE MEDICAL COLLEGE OF WISCONSIN, INC. , UWM RESEARCH FOUNDATION, INC.
发明人： Thomas Michael Ernst , Thomas Edmund Prieto , Brian Stewart Randall Armstrong
IPC分类号： A61B5/00 , A61B5/055 , A61B6/04 , A61B5/11 , G01R33/28 , G01R33/565 , G06T7/00 , A61B6/00 , G06K9/00 , H04N7/18 , G06T7/70 , G06K9/32 , G06K17/00
CPC分类号： A61B5/055 , A61B5/0077 , A61B5/1127 , A61B5/1128 , A61B5/721 , A61B5/7292 , A61B6/0492 , A61B6/547 , G01R33/28 , G01R33/56509 , G06K9/00624 , G06K2009/3291 , G06K2017/0045 , G06T7/0012 , G06T7/70 , H04N7/18
摘要： This invention relates to a system that adaptively compensates for subject motion in real-time in an imaging system. An object orientation marker (30), preferably a retro-grate reflector (RGR), is placed on the head or other body organ of interest of a patient (P) during a scan, such as an MRI scan. The marker (30) makes it possible to measure the six degrees of freedom (x, y, and z-translations, and pitch, yaw, and roll), or “pose”, required to track motion of the organ of interest. A detector, preferably a camera (40), observes the marker (30) and continuously extracts its pose. The pose from the camera (40) is sent to the scanner (120) via an RGR processing computer (50) and a scanner control and processing computer (100), allowing for continuous correction of scan planes and position (in real-time) for motion of the patient (P). This invention also provides for internal calibration and for co-registration over time of the scanner's and tracking system's reference frames to compensate for drift and other inaccuracies that may arise over time.

5. 发明申请

US20140100552A1 VASCULAR ACCESS SYSTEMS HAVING A GUIDEWIRE ANTI-MIGRATION FEATURE 有权
标题翻译：具有GUIDEWIRE抗转移特征的血管通路系统
公开(公告)号：US20140100552A1
公开(公告)日：2014-04-10
申请号：US14044590
申请日：2013-10-02
申请人： The Queen's Medical Center
发明人： Thomas Scott Gallacher , Jeffrey N. Yu
IPC分类号： A61M25/09
CPC分类号： A61M25/09041 , A61M25/0097 , A61M25/0169 , A61M25/09 , A61M39/20 , A61M2025/09125
摘要： Disclosed herein is a removable cap for connection to an input port of a catheter, comprising a proximal end having a lumen configured to house a guidewire therethrough; a distal end configured to reversibly mate with a luer lock of the input port of a catheter, the distal end having a lumen configured to house the guidewire therethrough; and a tubular body between the proximal end and the distal end, wherein the tubular body comprises an anti-migration feature transformable between a first configuration to allow slidable movement of the guidewire within the cap in a first direction toward the patient, and a second configuration to prevent slidable movement of the guidewire within the cap in the first direction toward the patient. Systems and methods are also disclosed.
摘要翻译：本文公开了一种用于连接到导管的输入端口的可移除盖，包括近端，其具有被配置为容纳穿过其中的导丝的内腔; 远端构造成与导管的输入端口的鲁尔锁可逆地配合，所述远端具有被配置为容纳导丝通过其的腔; 以及在所述近端和远端之间的管状体，其中所述管状体包括可在第一构型之间变换的抗迁移特征，所述第一构型允许所述导丝在所述帽内朝向所述患者朝第一方向滑动移动;以及第二构造以防止导线在第一方向上朝着患者体内在帽内滑动。还公开了系统和方法。

6. 发明申请

US20140037174A1 MOTION TRACKING SYSTEM FOR REAL TIME ADAPTIVE IMAGING AND SPECTROSCOPY 有权
标题翻译：用于实时自适应成像和光谱的运动跟踪系统
公开(公告)号：US20140037174A1
公开(公告)日：2014-02-06
申请号：US14034252
申请日：2013-09-23
申请人： The Queen's Medical Center , UWM Research Foundation, Inc. , The Medical College of Wisconsin, Inc. , The University of Hawaii
发明人： Thomas Michael Ernst , Thomas Edmund Prieto , Brian Stewart Randall Armstrong
IPC分类号： G01R33/565 , G06T7/00
CPC分类号： A61B5/055 , A61B5/0077 , A61B5/1127 , A61B5/1128 , A61B5/721 , A61B5/7292 , A61B6/0492 , A61B6/547 , G01R33/28 , G01R33/56509 , G06K9/00624 , G06K2009/3291 , G06K2017/0045 , G06T7/0012 , G06T7/70 , H04N7/18
摘要： This invention relates to a system that adaptively compensates for subject motion in real-time in an imaging system. An object orientation marker (30), preferably a retro-grate reflector (RGR), is placed on the head or other body organ of interest of a patient (P) during a scan, such as an MRI scan. The marker (30) makes it possible to measure the six degrees of freedom (x, y, and z-translations, and pitch, yaw, and roll), or “pose”, required to track motion of the organ of interest. A detector, preferably a camera (40), observes the marker (30) and continuously extracts its pose. The pose from the camera (40) is sent to the scanner (120) via an RGR processing computer (50) and a scanner control and processing computer (100), allowing for continuous correction of scan planes and position (in real-time) for motion of the patient (P). This invention also provides for internal calibration and for co-registration over time of the scanner's and tracking system's reference frames to compensate for drift and other inaccuracies that may arise over time.
摘要翻译：本发明涉及一种在成像系统中实时补偿被摄体运动的系统。在诸如MRI扫描的扫描期间，将物体取向标记（30），优选逆格栅反射器（RGR）放置在患者（P）的感兴趣的头部或其他身体器官上。标记（30）使得可以测量跟踪感兴趣的器官的运动所需的六个自由度（x，y和z-平移，俯仰，偏航和滚动）或“姿势”。检测器，优选地是照相机（40），观察标记物（30）并连续提取其姿态。来自相机（40）的姿势经由RGR处理计算机（50）和扫描仪控制和处理计算机（100）发送到扫描器（120），允许扫描平面和位置（实时）的连续校正，用于患者（P）的运动。本发明还提供内部校准和随着扫描器和跟踪系统的参考帧随时间的共同配准，以补偿随时间可能出现的漂移和其他不准确。

7. 发明授权

US08571293B2 Motion tracking system for real time adaptive imaging and spectroscopy 有权
标题翻译：用于实时自适应成像和光谱的运动跟踪系统
公开(公告)号：US08571293B2
公开(公告)日：2013-10-29
申请号：US13735907
申请日：2013-01-07
申请人： The Queen's Medical Center , The University of Hawaii , The Medical College of Wisconsin, Inc. , UWM Research Foundation, Inc.
发明人： Thomas Michael Ernst , Thomas Edmund Prieto , Brian Stewart Randall Armstrong
IPC分类号： G06K9/00
CPC分类号： A61B5/055 , A61B5/0077 , A61B5/1127 , A61B5/1128 , A61B5/721 , A61B5/7292 , A61B6/0492 , A61B6/547 , G01R33/28 , G01R33/56509 , G06K9/00624 , G06K2009/3291 , G06K2017/0045 , G06T7/0012 , G06T7/70 , H04N7/18
摘要： This invention relates to a system that adaptively compensates for subject motion in real-time in an imaging system. An object orientation marker (30), preferably a retro-grate reflector (RGR), is placed on the head or other body organ of interest of a patient (P) during a scan, such as an MRI scan. The marker (30) makes it possible to measure the six degrees of freedom (x, y, and z-translations, and pitch, yaw, and roll), or “pose”, required to track motion of the organ of interest. A detector, preferably a camera (40), observes the marker (30) and continuously extracts its pose. The pose from the camera (40) is sent to the scanner (120) via an RGR processing computer (50) and a scanner control and processing computer (100), allowing for continuous correction of scan planes and position (in real-time) for motion of the patient (P). This invention also provides for internal calibration and for co-registration over time of the scanner's and tracking system's reference frames to compensate for drift and other inaccuracies that may arise over time.
摘要翻译：本发明涉及一种在成像系统中实时补偿被摄体运动的系统。在诸如MRI扫描的扫描期间，将物体取向标记（30），优选逆格栅反射器（RGR）放置在患者（P）的感兴趣的头部或其他身体器官上。标记（30）使得可以测量跟踪感兴趣的器官的运动所需的六个自由度（x，y和z-平移，俯仰，偏航和滚动）或“姿势”。检测器，优选地是照相机（40），观察标记物（30）并连续提取其姿态。来自相机（40）的姿势经由RGR处理计算机（50）和扫描仪控制和处理计算机（100）发送到扫描器（120），允许扫描平面和位置（实时）的连续校正，用于患者（P）的运动。本发明还提供内部校准和随着扫描器和跟踪系统的参考帧随时间的共同配准，以补偿随时间可能出现的漂移和其他不准确。

8. 发明申请

US20130188830A1 MOTION TRACKING SYSTEM FOR REAL TIME ADAPTIVE IMAGING AND SPECTROSCOPY 有权
标题翻译：用于实时自适应成像和光谱的运动跟踪系统
公开(公告)号：US20130188830A1
公开(公告)日：2013-07-25
申请号：US13735907
申请日：2013-01-07
申请人： THE QUEEN'S MEDICAL CENTER , THE UNIVERSITY OF HAWAII , THE MEDICAL COLLEGE OF WISCONSIN, INC. , UWM RESEARCH FOUNDATION, INC.
发明人： Thomas Michael Ernst , Thomas Edmund Prieto , Brian Stewart Randall Armstrong
IPC分类号： A61B5/055
CPC分类号： A61B5/055 , A61B5/0077 , A61B5/1127 , A61B5/1128 , A61B5/721 , A61B5/7292 , A61B6/0492 , A61B6/547 , G01R33/28 , G01R33/56509 , G06K9/00624 , G06K2009/3291 , G06K2017/0045 , G06T7/0012 , G06T7/70 , H04N7/18
摘要： This invention relates to a system that adaptively compensates for subject motion in real-time in an imaging system. An object orientation marker (30), preferably a retro-grate reflector (RGR), is placed on the head or other body organ of interest of a patient (P) during a scan, such as an MRI scan. The marker (30) makes it possible to measure the six degrees of freedom (x, y, and z-translations, and pitch, yaw, and roll), or “pose”, required to track motion of the organ of interest. A detector, preferably a camera (40), observes the marker (30) and continuously extracts its pose. The pose from the camera (40) is sent to the scanner (120) via an RGR processing computer (50) and a scanner control and processing computer (100), allowing for continuous correction of scan planes and position (in real-time) for motion of the patient (P). This invention also provides for internal calibration and for co-registration over time of the scanner's and tracking system's reference frames to compensate for drift and other inaccuracies that may arise over time.
摘要翻译：本发明涉及一种在成像系统中实时补偿被摄体运动的系统。在诸如MRI扫描的扫描期间，将物体取向标记（30），优选逆格栅反射器（RGR）放置在患者（P）的感兴趣的头部或其他身体器官上。标记（30）使得可以测量跟踪感兴趣的器官的运动所需的六个自由度（x，y和z-平移，俯仰，偏航和滚动）或“姿势”。检测器，优选地是照相机（40），观察标记物（30）并连续提取其姿态。来自相机（40）的姿势经由RGR处理计算机（50）和扫描仪控制和处理计算机（100）发送到扫描器（120），允许扫描平面和位置（实时）的连续校正，用于患者（P）的运动。本发明还提供内部校准和随着扫描器和跟踪系统的参考帧随时间的共同配准，以补偿随时间可能出现的漂移和其他不准确。

9. 发明申请

US20210186353A1 MOTION TRACKING SYSTEM FOR REAL TIME ADAPTIVE IMAGING AND SPECTROSCOPY 有权
公开(公告)号：US20210186353A1
公开(公告)日：2021-06-24
申请号：US17121585
申请日：2020-12-14
申请人： THE QUEEN'S MEDICAL CENTER , THE UNIVERSITY OF HAWAII , THE MEDICAL COLLEGE OF WISCONSIN, INC. , UWM RESEARCH FOUNDATION, INC.
发明人： Thomas Michael Ernst , Thomas Edmund Prieto , Brian Stewart Randall Armstrong
IPC分类号： A61B5/055 , A61B6/04 , G06T7/70 , A61B5/00 , G01R33/28 , A61B5/11 , G01R33/565 , G06T7/00 , A61B6/00 , G06K9/00 , H04N7/18
摘要： This invention relates to a system that adaptively compensates for subject motion in real-time in an imaging system. An object orientation marker (30), preferably a retro-grate reflector (RGR), is placed on the head or other body organ of interest of a patient (P) during a scan, such as an MRI scan. The marker (30) makes it possible to measure the six degrees of freedom (x, y, and z-translations, and pitch, yaw, and roll), or “pose”, required to track motion of the organ of interest. A detector, preferably a camera (40), observes the marker (30) and continuously extracts its pose. The pose from the camera (40) is sent to the scanner (120) via an RGR processing computer (50) and a scanner control and processing computer (100), allowing for continuous correction of scan planes and position (in real-time) for motion of the patient (P). This invention also provides for internal calibration and for co-registration over time of the scanner's and tracking system's reference frames to compensate for drift and other inaccuracies that may arise over time.

10. 发明授权

US10660541B2 Systems, devices, and methods for detecting false movements for motion correction during a medical imaging scan 有权
公开(公告)号：US10660541B2
公开(公告)日：2020-05-26
申请号：US15920020
申请日：2018-03-13
申请人： The University of Hawai'i , The Queen's Medical Center
发明人： Thomas Michael Ernst , Brian Keating , Aditya Singh , Maxim Zaitsev , Michael Herbst
IPC分类号： G06K9/00 , A61B5/055 , G06K9/62 , G06K9/66 , G06T7/00 , A61B5/00 , A61B5/11 , G06T7/246
摘要： The systems, methods, and devices described herein generally relate to achieving accurate and robust motion correction by detecting and accounting for false movements in motion correction systems used in conjunction with medical imaging and/or therapeutic systems. In other words, in some embodiments of the systems, methods, and devices described herein can be configured to detect false movements for motion correction during a medical imaging scan and/or therapeutic procedure, and thereby ensure that such false movements are not accounted for in the motion correction process. Upon detection of false movements, the imaging or therapeutic system can be configured to transiently suppress and/or subsequently repeat acquisitions.

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式