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1. 发明专利

CA2153720A1 EXPRESSION SYSTEMS UTILIZING AUTOLYZING FUSION PROTEINS AND A NOVEL REDUCING POLYPEPTIDE 未知
公开(公告)号：CA2153720A1
公开(公告)日：1996-01-14
申请号：CA2153720
申请日：1995-07-12
申请人： TAKAHASHI TOHRU , KOISHI RYUTA , KAWASHIMA ICHIRO , SERIZAWA NOBUFUSA
发明人： TAKAHASHI TOHRU , KOISHI RYUTA , KAWASHIMA ICHIRO , SERIZAWA NOBUFUSA
IPC分类号： C12N15/53 , A61K38/00 , A61K38/44 , A61K39/12 , A61P7/12 , A61P9/10 , C07K14/08 , C07K14/54 , C07K16/10 , C07K16/40 , C12N1/21 , C12N5/12 , C12N5/18 , C12N9/02 , C12N9/50 , C12N15/24 , C12N15/40 , C12N15/62 , C12N15/70 , C12Q1/686 , C12Q1/6876 , C12R1/19 , G01N33/573 , C07K19/00 , C07H21/04 , C07K1/22 , C12N15/57
摘要： The present invention provides expression systems for exogenous polypeptides wherein the polypeptide is expressed as a fusion protein together with clover yellow virus Nuclear Inclusion a (NIa), the NIa component serving to autolyze the fusion protein after expression. This system can be used to express a novel polypeptide which we have designated KM31-7 protein and which is capable of reducing dichloroindophenol and reduced glutathione. This polypeptide is useful in the treatment of disorders caused by oxidative stress.

2. 发明申请

WO2008141266A1 TWO - DIMENSIONAL CODE SCANNER WITH GUIDE ILLUMINATION 审中-公开
标题翻译：具有指导照明的两维码扫描器
公开(公告)号：WO2008141266A1
公开(公告)日：2008-11-20
申请号：PCT/US2008/063383
申请日：2008-05-12
申请人： OPTOELECTRONICS CO., LTD. , OPTICON, INC. , TAKAHASHI, Tohru
发明人： TAKAHASHI, Tohru
IPC分类号： G06K7/10
CPC分类号： G06K7/10702
摘要： A bar code scanner is disclosed which may include an LED. The LED includes a light source that emits light. The bar code scanner may also include a lens set. The lens set includes a back side and a front side. The front side includes a plurality of spherical lobes. When light from the light source is incident on the back side of the lens set, each of the spherical lobes preferably focuses the light into a light beam, which is then generated from each of the lobes. In certain embodiments of the invention, the LED can be mounted on the back side of a circuit board in such a fashion as to protrude through the aperture in the circuit board and then to shine light on the lens set.
摘要翻译：公开了一种条形码扫描器，其可以包括LED。 LED包括发光的光源。条形码扫描器还可以包括透镜组。透镜组包括后侧和前侧。前侧包括多个球形凸起。当来自光源的光入射到透镜组的背面时，每个球形波瓣优选地将光聚焦成光束，然后从每个凸角产生光束。在本发明的某些实施例中，LED可以安装在电路板的背面，以便突出穿过电路板中的孔，然后将光照射在透镜组上。

3. 发明申请

WO2007032957A2 TEMPERATURE COMPENSATED LASER FOCUSING OPTICS 审中-公开
标题翻译：温度补偿激光聚焦光学
公开(公告)号：WO2007032957A2
公开(公告)日：2007-03-22
申请号：PCT/US2006/034529
申请日：2006-09-06
申请人： OPTOELECTRONICS CO., LTD. , OPTICON, INC. , TAKAHASHI, Tohru
发明人： TAKAHASHI, Tohru
IPC分类号： H01S3/04
CPC分类号： H01S5/02212 , H01S5/02288
摘要： A laser source assembly comprises a laser diode for generating a laser beam and a focusing lens for focusing the light beam. A spacer is provided for keeping the diode and the lens at a predetermined distance, and is made of a material of low expansion coefficient. Preferably, the subassembly constituted of the diode, the spacer and the lens is housed in a case made of another material that may have a higher expansion coefficient. A resilient element is provided to continuously keep the diode and the lens abutting on the opposite ends of the spacer.
摘要翻译：激光源组件包括用于产生激光束的激光二极管和用于聚焦光束的聚焦透镜。提供了用于将二极管和透镜保持在预定距离的间隔物，并且由具有低膨胀系数的材料制成。优选地，由二极管，间隔物和透镜构成的子组件容纳在由具有较高膨胀系数的其它材料制成的壳体中。提供弹性元件以连续地保持二极管和透镜抵靠在间隔物的相对端上。

4. 发明申请

WO2002061794A2 COLOR CATHODE LAY TUBE AND METHOD OF MANUFACTURING THE SAME 审中-公开
标题翻译：彩色阴极层管及其制造方法
公开(公告)号：WO2002061794A2
公开(公告)日：2002-08-08
申请号：PCT/JP2002/000567
申请日：2002-01-25
申请人： KABUSHIKI KAISHA TOSHIBA , TAKAHASHI, Tohru , INOUE, Masatsugu , FUKUDA, Kumio , NIKAIDO, Masaru , SHIOZAWA, Hitoshi , NAKAMURA, Akiyoshi , ISHIKAWA, Satoshi
发明人： TAKAHASHI, Tohru , INOUE, Masatsugu , FUKUDA, Kumio , NIKAIDO, Masaru , SHIOZAWA, Hitoshi , NAKAMURA, Akiyoshi , ISHIKAWA, Satoshi
IPC分类号： H01J29/07
CPC分类号： H01J29/07 , H01J9/142 , H01J9/146 , H01J29/58 , H01J2229/0777
摘要： A shadow mask is arranged to face a phosphor screen formed on an inner surface of a panel. A plurality of aperture columns are formed in parallel in the shadow mask. Each aperture column includes a plurality of apertures arranged in line at a predetermined interval. On both sides of each aperture column on the surface of the shadow mask facing the electron gun, stripe-shaped dielectric layers for acting on electron beams toward the apertures are formed respectively, and extend in substantial parallel with the aperture columns. The shadow mask is manufactured in such a manner that stripe-shaped insulating material layers are formed on the surface of a mask base material facing the electron gun, the mask base material is thereafter shaped into a predetermined shape, and the insulating material layers on the shaped mask are sintered.
摘要翻译：荫罩布置为面对形成在面板内表面上的荧光屏。在荫罩中平行形成多个孔列。每个孔径列包括以预定间隔排列成直线的多个孔径。在面对电子枪的荫罩表面上的每个孔列的两侧分别形成用于作用于电子束朝向孔的条形电介质层，并且基本上平行于孔列延伸。荫罩是这样制造的，即在面对电子枪的荫罩基底材料的表面上形成条形绝缘材料层，然后将荫罩基底材料成形为预定的形状，并将绝缘材料层形状的掩模被烧结。

5. 发明申请

WO2009102336A1 SYSTEM AND METHOD FOR COUPLING A LENS TO A PRINTED CIRCUIT 审中-公开
标题翻译：将镜头耦合到印刷电路的系统和方法
公开(公告)号：WO2009102336A1
公开(公告)日：2009-08-20
申请号：PCT/US2008/054091
申请日：2008-02-15
申请人： OPTOELECTRONICS CO., LTD. , OPTICON. INC. , SATOSHI, Komi , TAKAHASHI, Tohru
发明人： SATOSHI, Komi , TAKAHASHI, Tohru
IPC分类号： G03B17/00
CPC分类号： G03B17/12 , H04N5/2254 , H05K1/112 , H05K1/118 , H05K3/28 , H05K2201/09436
摘要： An optical assembly is disclosed which may include a lens having first and second electrodes; and a flexible printed circuit (FPC) configured for placement in proximity to the lens, wherein the FPC may include a bottom insulating layer; a top insulating layer; and an FPC electrode configured to contact the second electrode of the lens, wherein the FPC electrode may include a center portion disposed between the bottom and top insulating layers of the FPC; a post connected to the center portion and extending through the top insulating layer of the FPC; and a contact layer connected to the post and configured to provide the contact with the second electrode of the lens.
摘要翻译：公开了一种光学组件，其可以包括具有第一和第二电极的透镜; 以及配置用于放置在所述透镜附近的柔性印刷电路（FPC），其中所述FPC可以包括底部绝缘层; 顶部绝缘层; 以及配置成与透镜的第二电极接触的FPC电极，其中FPC电极可以包括设置在FPC的底部和顶部绝缘层之间的中心部分; 连接到中心部分并延伸穿过FPC的顶部绝缘层的柱; 以及连接到所述柱并且被配置为提供与所述透镜的第二电极的接触的接触层。

6. 发明申请

WO2007032957A3 TEMPERATURE COMPENSATED LASER FOCUSING OPTICS 审中-公开
标题翻译：温度补偿激光聚焦光学
公开(公告)号：WO2007032957A3
公开(公告)日：2007-11-08
申请号：PCT/US2006034529
申请日：2006-09-06
申请人： OPTOELECTRONICS CO LTD , OPTICON INC , TAKAHASHI TOHRU
发明人： TAKAHASHI TOHRU
IPC分类号： G02B7/02
CPC分类号： H01S5/02212 , H01S5/02288
摘要： A laser source assembly comprises a laser diode for generating a laser beam and a focusing lens for focusing the light beam. A spacer is provided for keeping the diode and the lens at a predetermined distance, and is made of a material of low expansion coefficient. Preferably, the subassembly constituted of the diode, the spacer and the lens is housed in a case made of another material that may have a higher expansion coefficient. A resilient element is provided to continuously keep the diode and the lens abutting on the opposite ends of the spacer.
摘要翻译：激光源组件包括用于产生激光束的激光二极管和用于聚焦光束的聚焦透镜。提供隔离物以使二极管和透镜保持预定的距离，并且由低膨胀系数的材料制成。优选地，由二极管，隔离物和透镜构成的子组件容纳在由可以具有较高膨胀系数的另一种材料制成的壳体中。提供弹性元件以连续保持二极管和透镜抵靠在间隔件的相对端上。

7. 发明申请

WO1989007787A1 METHOD OF PREPARING SUBSTRATE HAVING PATTERN FORMED THEREON 审中-公开
标题翻译：制备形成图案的基板的方法
公开(公告)号：WO1989007787A1
公开(公告)日：1989-08-24
申请号：PCT/JP1989000152
申请日：1989-02-15
申请人： TERUMO KABUSHIKI KAISHA , MURAHARA, Masataka , SHIMOMURA, Takeshi , TAKAHASHI, Tohru
发明人： TERUMO KABUSHIKI KAISHA
IPC分类号： G03F07/20
CPC分类号： G03F7/027
摘要： A method of preparing a substrate having a pattern of a high-resolution formed thereon by irradiating a resist-coated substrate through a mask with a beam having a wavelength shorter than 300 nm at a dose smaller than 2 J/cm .
摘要翻译：通过以小于2J / cm 2的剂量用波长短于300nm的光束通过掩模照射抗蚀剂涂覆的基板来制备具有高分辨率图案的基板的方法。

8. 发明申请

WO2008143612A1 BAR CODE SCANNER WITH ENVIRONMENTAL SENSING 审中-公开
标题翻译：条形码扫描器与环境感应
公开(公告)号：WO2008143612A1
公开(公告)日：2008-11-27
申请号：PCT/US2007/011824
申请日：2007-05-17
申请人： OPTOELECTRONICS CO., LTD. , OPTICON, INC. , HOSOI, Kazukuni , TAKAHASHI, Tohru
发明人： HOSOI, Kazukuni , TAKAHASHI, Tohru
IPC分类号： G06K7/10
CPC分类号： G06K7/10891
摘要： A bar code scanner (10) is disclosed which may include a scanner gun (100); and at least one sensor (104) in communication with the scanner gun (100), wherein the at least one sensor (104) is operable to detect at least one operating condition of the bar code scanner(10).
摘要翻译：公开了一种条形码扫描器（10），其可包括扫描枪（100）; 和与扫描枪（100）连通的至少一个传感器（104），其中所述至少一个传感器（104）可操作以检测所述条形码扫描器（10）的至少一个操作状态。

9. 发明申请

WO2012045481A3 ANTIBODY TARGETING OSTEOCLAST-RELATED PROTEIN SIGLEC-15 审中-公开
标题翻译：抗体靶向与OSTEOCLAST相关的蛋白质信号15
公开(公告)号：WO2012045481A3
公开(公告)日：2012-08-16
申请号：PCT/EP2011005219
申请日：2011-10-04
申请人： DAIICHI SANKYO CO LTD , WATANABE ICHIRO , HIRUMA YOSHIHARU , TSUDA EISUKE , MATSUOKA TATSUJI , OHTSUKA TOSHIAKI , TAKAHASHI TOHRU , AGATSUMA TOSHINORI , MILLER SANDRA , MACEK ROBERT , BAEHS KATHRIN-LADETZKI , RUNZ STEFFEN , SCHUBERT ULRIKE , SCHUSTER INGRID , PONSEL DIRK
发明人： WATANABE ICHIRO , HIRUMA YOSHIHARU , TSUDA EISUKE , MATSUOKA TATSUJI , OHTSUKA TOSHIAKI , TAKAHASHI TOHRU , AGATSUMA TOSHINORI , MILLER SANDRA , MACEK ROBERT , BAEHS KATHRIN-LADETZKI , RUNZ STEFFEN , SCHUBERT ULRIKE , SCHUSTER INGRID , PONSEL DIRK
IPC分类号： C07K16/28
CPC分类号： A61K39/3955 , A61K45/06 , A61K2039/505 , C07K16/2803 , C07K2317/21 , C07K2317/55 , C07K2317/92
摘要： An isolated antibody capable of binding Siglec-15 which inhibits osteoclast formation and/or osteoclastic bone resorption, or a functional fragment thereof. The heavy chain of the antibody comprises a CDRH1 comprising a sequence having at least 80% sequence identity to SEQ ID NO: 106, a CDRH2 comprising a sequence having at least 80% sequence identity to SEQ ID NO: 107, and a CDRH3 comprising a sequence having at least 80% sequence identity to one of SEQ ID NOS: 35, 45, 55, 65 or 80. The light chain of the antibody comprises a CDRL1 comprising a sequence having at least 80% sequence identity to SEQ ID NO: 73 or 83, a CDRL2 comprising a sequence having at least 80% sequence identity to SEQ ID NO: 108, and a CDRL3 comprising a sequence having at least 80% sequence identity to one of SEQ ID NOS: 40, 50, 60, 70, 90, 100 or 109.
摘要翻译：能够结合抑制破骨细胞形成和/或破骨细胞骨吸收的Siglec-15的分离抗体或其功能片段。抗体的重链包含CDRH1，其包含与SEQ ID NO：106具有至少80％序列同一性的序列，CDRH2包含与SEQ ID NO：107具有至少80％序列同一性的序列，以及CDRH3，其包含具有与SEQ ID NO：35,45,55,65或80之一具有至少80％序列同一性的序列。抗体的轻链包含CDRL1，其包含与SEQ ID NO：73具有至少80％序列同一性的序列或83，CDRL2，其包含与SEQ ID NO：108具有至少80％序列同一性的序列，和CDRL3，其包含与SEQ ID NO：40,50,60,70， 90，100或109。

10. 发明申请

WO2012045481A2 ANTIBODY TARGETING OSTEOCLAST-RELATED PROTEIN SIGLEC-15 审中-公开
标题翻译：抗体靶向与种子细胞相关的蛋白质SIGLEC-15
公开(公告)号：WO2012045481A2
公开(公告)日：2012-04-12
申请号：PCT/EP2011/005219
申请日：2011-10-04
申请人： DAIICHI SANKYO COMPANY, LIMITED , WATANABE, Ichiro , HIRUMA, Yoshiharu , TSUDA, Eisuke , MATSUOKA, Tatsuji , OHTSUKA, Toshiaki , TAKAHASHI, Tohru , AGATSUMA, Toshinori , MILLER, Sandra , MACEK, Robert , BAEHS, Kathrin-Ladetzki , RUNZ, Steffen , SCHUBERT, Ulrike , SCHUSTER, Ingrid , PONSEL, Dirk
发明人： WATANABE, Ichiro , HIRUMA, Yoshiharu , TSUDA, Eisuke , MATSUOKA, Tatsuji , OHTSUKA, Toshiaki , TAKAHASHI, Tohru , AGATSUMA, Toshinori , MILLER, Sandra , MACEK, Robert , BAEHS, Kathrin-Ladetzki , RUNZ, Steffen , SCHUBERT, Ulrike , SCHUSTER, Ingrid , PONSEL, Dirk
IPC分类号： C07K16/28
CPC分类号： A61K39/3955 , A61K45/06 , A61K2039/505 , C07K16/2803 , C07K2317/21 , C07K2317/55 , C07K2317/92
摘要： An isolated antibody capable of binding Siglec-15 which inhibits osteoclast formation and/or osteoclastic bone resorption, or a functional fragment thereof. The heavy chain of the antibody comprises a CDRH1 comprising a sequence having at least 80% sequence identity to SEQ ID NO: 106, a CDRH2 comprising a sequence having at least 80% sequence identity to SEQ ID NO: 107, and a CDRH3 comprising a sequence having at least 80% sequence identity to one of SEQ ID NOS: 35, 45, 55, 65 or 80. The light chain of the antibody comprises a CDRL1 comprising a sequence having at least 80% sequence identity to SEQ ID NO: 73 or 83, a CDRL2 comprising a sequence having at least 80% sequence identity to SEQ ID NO: 108, and a CDRL3 comprising a sequence having at least 80% sequence identity to one of SEQ ID NOS: 40, 50, 60, 70, 90, 100 or 109.
摘要翻译：能够结合抑制破骨细胞形成和/或破骨细胞骨吸收的Siglec-15的分离的抗体，或其功能片段。抗体的重链包含CDRH1和CDRH3，CDRH1包含与SEQ ID NO：106具有至少80％序列同一性的序列，CDRH2包含与SEQ ID NO：107具有至少80％序列同一性的序列，CDRH3包含序列与SEQ ID NO：35,45,55,65或80之一具有至少80％的序列同一性。抗体的轻链包含CDRL1，该CDRL1包含与SEQ ID NO：73具有至少80％序列同一性的序列或83的序列，包含与SEQ ID NO：108具有至少80％序列同一性的序列的CDRL2，和包含与SEQ ID NO：40,50,60,70,80,90， 90,100或109。

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