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1. 发明授权

US08849954B2 Apparatus and method for managing multimedia playback 有权
标题翻译：用于管理多媒体播放的装置和方法
公开(公告)号：US08849954B2
公开(公告)日：2014-09-30
申请号：US10964806
申请日：2004-10-15
申请人： Sung-geun Kim
发明人： Sung-geun Kim
IPC分类号： H04N9/80 , G06F15/16 , G11B20/10
CPC分类号： G11B27/11 , G11B20/10 , G11B2020/10972 , G11B2220/2562 , H04N9/87
摘要： An apparatus and method of managing reproduction of multimedia contents. A multimedia reproduction method includes: receiving identification information on predetermined multimedia contents; receiving first reproduction information on the predetermined multimedia contents, from a multimedia reproduction management apparatus receiving the transmitted identification information; and if first identification information contained in the received first reproduction information corresponds with the transmitted identification information, reproducing the predetermined multimedia contents based on the first reproduction information. According to the apparatus and method, even when a DVD title being played back is replaced by another DVD title, or when the power of a DVD playback apparatus is suddenly interrupted, the reproduction position information is safely maintained.
摘要翻译：一种管理多媒体内容的再现的装置和方法。多媒体再现方法包括：接收关于预定多媒体内容的识别信息; 从接收所发送的识别信息的多媒体再现管理装置接收关于预定多媒体内容的第一再现信息; 并且如果所接收的第一再现信息中包含的第一识别信息与所发送的识别信息相对应，则基于第一再现信息再现预定的多媒体内容。根据该装置和方法，即使正在播放的DVD标题被另一DVD标题替代，或者当DVD播放装置的电源突然中断时，安全地保持再现位置信息。

2. 发明授权

US06314385B1 Method for controlling maintenance of semiconductor fabricating equipment arranged in a processing line 失效
标题翻译：用于控制处理线中布置的半导体制造设备的维护的方法
公开(公告)号：US06314385B1
公开(公告)日：2001-11-06
申请号：US09168094
申请日：1998-10-08
申请人： Sung-geun Kim , Byung-wan Kim
发明人： Sung-geun Kim , Byung-wan Kim
IPC分类号： G05B902
CPC分类号： G05B19/41875 , G05B2219/32209 , Y02P90/10 , Y02P90/14 , Y02P90/22
摘要： A method for controlling semiconductor fabricating equipment includes receiving at a maintenance module in a host computer first maintenance data generated from semiconductor fabricating equipment. A value of the first data is compared with a predesignated first reference threshold at the maintenance module. A warning message is displayed on a display device, if the value of the first data is not less than the first reference threshold. If the value of the first data is not less than the first reference threshold, second maintenance data is received, and it is determined whether maintenance of the fabricating equipment occurred. If not, the value of the second data is compared with a predesignated second reference threshold at the maintenance module. If the value of the second data is not less than the second reference threshold, the fabricating equipment is interlocked by the maintenance module, and the fabricating equipment is stopped.
摘要翻译：一种用于控制半导体制造设备的方法包括在主机中的维护模块处接收由半导体制造设备产生的第一维护数据。在维护模块处将第一数据的值与预先指定的第一参考阈值进行比较。如果第一数据的值不小于第一参考阈值，则在显示装置上显示警告消息。如果第一数据的值不小于第一参考阈值，则接收第二维护数据，并且确定是否发生制造设备的维护。如果不是，则在维护模块处将第二数据的值与预先指定的第二参考阈值进行比较。如果第二数据的值不小于第二参考阈值，则制造设备由维护模块互锁，制造设备停止。

3. 发明授权

US06308112B1 Method for controlling emergency states of semiconductor fabricating equipment arranged in a processing line 失效
标题翻译：用于控制布置在处理线中的半导体制造设备的紧急状态的方法
公开(公告)号：US06308112B1
公开(公告)日：2001-10-23
申请号：US09148632
申请日：1998-09-04
申请人： Sung-geun Kim , Jong-hwa Park
发明人： Sung-geun Kim , Jong-hwa Park
IPC分类号： G06F1900
CPC分类号： H01L21/67294 , G05B23/0286 , H01L21/67276
摘要： A method for controlling emergency states of equipment in a semiconductor fabrication system includes determining whether on-line communication has been restored between a host computer and semiconductor fabrication equipment after an interruption in communication. If on-line communication has been restored, post-restoration emergency state data are received automatically from the equipment. Then it is determined whether the post-restoration emergency state data indicate the equipment is in a warning state. If the post-restoration emergency state data indicate the warning state, it is determined whether the warning state is a critical state. If the warning state is the critical state, a key value of a variable ID corresponding to the equipment is changed to a value indicative of shutting down the equipment. Then the equipment is shut down by inserting the variable ID into an equipment control message and downloading the equipment control message to the equipment. As a result, unforeseen operational problems can be prevented in advance and the work load of the operator can be considerably reduced.
摘要翻译：一种用于控制半导体制造系统中的设备的紧急状态的方法，包括：在通信中断之后，确定在主计算机和半导体制造设备之间是否已经恢复了在线通信。如果在线通信恢复，则自动从设备接收恢复后的紧急状态数据。然后确定恢复后紧急状态数据是否指示设备处于警告状态。如果恢复后紧急状态数据指示警告状态，则确定警告状态是否是关键状态。如果警告状态为临界状态，则与设备对应的变量ID的键值变为表示关闭设备的值。然后通过将变量ID插入到设备控制消息中并将设备控制消息下载到设备来关闭设备。结果，可以预先防止意外的操作问题，并且可以显着地减少操作者的工作负荷。

4. 发明授权

US10078085B2 Screening and engineering method of super-stable immunoglobulin variable domains and their uses 有权
公开(公告)号：US10078085B2
公开(公告)日：2018-09-18
申请号：US14422912
申请日：2012-08-22
申请人： Hyung-Kwon Lim , Sung Geun Kim , Young Seoub Park , Hyo Jung Nam , Dong-Sik Kim , Jae Chan Park , Yeup Yoon
发明人： Hyung-Kwon Lim , Sung Geun Kim , Young Seoub Park , Hyo Jung Nam , Dong-Sik Kim , Jae Chan Park , Yeup Yoon
IPC分类号： C40B40/10 , G01N33/68 , C07K16/00 , C07K16/18 , C07K16/32
CPC分类号： G01N33/6857 , C07K16/00 , C07K16/18 , C07K16/32 , C07K2317/21 , C07K2317/56 , C07K2317/565 , C07K2317/569 , C07K2317/94 , C07K2319/00 , C07K2319/10 , C40B40/10 , G01N2500/00
摘要： There are provided a method named Tat-associated protein engineering (TAPE), of screening a target protein having higher solubility and excellent thermostability, in particular, an immunoglobulin variable domain (VH or VL) derived from human germ cells, by preparing a gene construct where the target protein and an antibiotic-resistant protein are linked to a Tat signal sequence, and then expressing this within E. coli, and human or engineered VH and VL domain antibodies and human or engineered VH and VL domain antibody scaffolds having solubility and excellent thermostability, which are screened by the TAPE method. There are also provided a library including random CDR sequences in the human or engineered VH or VL domain antibody scaffold screened by the TAPE method, and a preparing method thereof. There are also provided a VH or VL domain antibody having binding ability to the target protein screened by using the library, and a pharmaceutical composition including the domain antibody.

5. 发明申请

US20100184136A1 Methods For Enhancing A Secretion Efficiency Of Recombinant Foreign Protein In Yeast Expression System 有权
标题翻译：用于增强酵母表达系统中重组外源蛋白的分泌效率的方法
公开(公告)号：US20100184136A1
公开(公告)日：2010-07-22
申请号：US12305768
申请日：2006-06-20
申请人： Hyung-Kwon Lim , Sung-Geun Kim
发明人： Hyung-Kwon Lim , Sung-Geun Kim
IPC分类号： C12P21/00
CPC分类号： C12N15/81
摘要： Provided is a method for improving secretion efficiency of a recombinant foreign protein in a yeast expression system. The method comprises transforming a yeast host with a recombinant foreign gene construct comprising a galactose-inducible promoter, a secretion signal sequence and a gene encoding the foreign protein to construct a transformed yeast strain; and culturing the transformed yeast strain under the condition that the activity of the galactose-inducible promoter is controlled. Improved secretion efficiency of the foreign protein can be achieved by decreasing over-expression-induced insoluble precipitation of the recombinant foreign protein suffered by a conventional galactose-inducible promoter-based yeast expression system, via appropriate control of a level of galactose functioning as an inducer of the galactose-inducible promoter in cells. Due to improved secretion efficiency of the recombinant foreign protein, present invention makes a contribution to improvement in productivity of recombinant foreign proteins in the yeast expression system and reduction in production costs.
摘要翻译：提供了一种用于提高酵母表达系统中重组外源蛋白的分泌效率的方法。该方法包括用包含半乳糖诱导型启动子，分泌信号序列和编码外源蛋白的基因的重组外源基因构建体来转化酵母宿主以构建转化的酵母菌株; 并在控制半乳糖诱导型启动子的活性的条件下培养转化的酵母菌株。通过适当控制用作诱导剂的半乳糖水平，通过减少由常规的基于半乳糖诱导型启动子的酵母表达系统所承受的重组外源蛋白质的过表达诱导的不溶性沉淀，可以实现外源蛋白质的分泌效率的提高。的半乳糖诱导型启动子。由于重组外源蛋白的分泌效率提高，本发明对于提高酵母表达系统中重组外源蛋白质的生产力和生产成本的降低有所贡献。

6. 发明申请

US20080187940A1 Transformed Saccharomyces Cerevisiae and Method For Mass-Production of Lk8 Protein Using the Same 有权
标题翻译：转化的酿酒酵母和使用它的大量生产Lk8蛋白的方法
公开(公告)号：US20080187940A1
公开(公告)日：2008-08-07
申请号：US10587155
申请日：2005-01-26
申请人： Hyung-Kwon Lim , Jung Hwan Park , Sung-Geun Kim
发明人： Hyung-Kwon Lim , Jung Hwan Park , Sung-Geun Kim
IPC分类号： G01N33/569 , C12N15/63 , C12P21/02 , C12N1/19
CPC分类号： C12N15/81 , C07K14/755
摘要： The present invention relates to a method for preparing LK8 protein, more precisely, a method for mass-production of LK8 protein using Saccharomyces cerevisiae transformed by a gene coding LK8 protein having angiogenesis inhibiting activity. The transformed strain of the present invention and production processes of LK8 protein are expected to contribute greatly to the commercialization of LK8 protein as a novel angiogenesis inhibitor.
摘要翻译：本发明涉及一种用于制备LK8蛋白的方法，更确切地说，涉及使用由编码具有血管发生抑制活性的LK8蛋白的基因转化的酿酒酵母来批量生产LK8蛋白的方法。预期本发明的转化菌株和LK8蛋白的生产过程对于作为新型血管发生抑制剂的LK8蛋白质的商业化有很大贡献。

7. 发明授权

US06304791B1 Method for controlling semiconductor equipment interlocked with a host computer 失效
标题翻译：用于控制与主机互锁的半导体设备的方法
公开(公告)号：US06304791B1
公开(公告)日：2001-10-16
申请号：US09137935
申请日：1998-08-21
申请人： Sung-geun Kim
发明人： Sung-geun Kim
IPC分类号： G06F1900
CPC分类号： G05B19/4184 , G05B2219/45032 , G05B2219/50106 , Y02P90/14
摘要： A method for controlling semiconductor fabrication equipment prevents an operator from accidently operating a piece of equipment which is in an interlocked state, since a host computer automatically stores information on any interlocked piece of equipment, and rechecks that information before allowing any product to be introduced into a piece of equipment. Optimal process conditions for each process are registered in the host computer. The registered optimal process condition is compared with process data reported from each piece of equipment. If it is determined that the reported data are in the range of the optimal process conditions in view of the comparison, it is then determined whether or not the reported data also satisfy a specific rule registered in the host computer. If it is determined that the reported data satisfy the specific rule, the process continues. Otherwise, if it is determined that the reported data do not satisfy the specific rule, the equipment and a tracking module of the host computer are simultaneously interlocked and the interlocking is automatically saved in the host computer. The process is stopped until the process failure is solved.
摘要翻译：一种用于控制半导体制造设备的方法防止操作者意外地操作处于联锁状态的设备，因为主计算机自动存储关于任何互锁的设备的信息，并且在允许任何产品被引入之前重新检查该信息一件设备。在主计算机中注册每个进程的最佳处理条件。将注册的最佳工艺条件与每台设备报告的过程数据进行比较。如果根据比较确定所报告的数据在最佳处理条件的范围内，则确定所报告的数据是否也满足在主计算机中登记的特定规则。如果确定报告的数据满足特定规则，则该过程继续。否则，如果确定报告的数据不满足特定规则，则主机的设备和跟踪模块同时互锁，并且互锁被自动保存在主计算机中。该过程停止，直到过程失败被解决。

8. 发明授权

US08298787B2 Methods for enhancing a secretion efficiency of recombinant foreign protein in yeast expression system 有权
标题翻译：提高酵母表达系统中重组外源蛋白的分泌效率的方法
公开(公告)号：US08298787B2
公开(公告)日：2012-10-30
申请号：US12305768
申请日：2006-06-20
申请人： Hyung-Kwon Lim , Sung-Geun Kim
发明人： Hyung-Kwon Lim , Sung-Geun Kim
IPC分类号： C12P21/06 , C12P21/04
CPC分类号： C12N15/81
摘要： Provided is a method for improving secretion efficiency of a recombinant foreign protein in a yeast expression system. The method includes transforming a yeast host with a recombinant foreign gene construct containing a galactose-inducible promoter, a secretion signal sequence and a gene encoding the foreign protein to construct a transformed yeast strain; and culturing the transformed yeast strain under the condition that the activity of the galactose-inducible promoter is controlled. Improved secretion efficiency of the foreign protein can be achieved by decreasing overexpression-induced insoluble precipitation of the recombinant foreign protein suffered by a conventional galactose-inducible promoter-based yeast expression system, via appropriate control of a level of galactose functioning as an inducer of the galactose-inducible promoter in cells. Due to improved secretion efficiency of the recombinant foreign protein, present invention makes a contribution to improvement in productivity of recombinant foreign proteins in the yeast expression system and reduction in production costs.
摘要翻译：提供了一种用于提高酵母表达系统中重组外源蛋白的分泌效率的方法。该方法包括用包含半乳糖诱导型启动子，分泌信号序列和编码外源蛋白的基因的重组外源基因构建体来转化酵母宿主以构建转化的酵母菌株; 并在控制半乳糖诱导型启动子的活性的条件下培养转化的酵母菌株。外源蛋白的分泌效率的提高可以通过减少由常规的基于半乳糖诱导型启动子的酵母表达系统所承受的重组外源蛋白的过度表达诱导的不溶性沉淀，通过适当控制作为诱导剂的诱导剂的半乳糖的水平来实现半乳糖诱导型启动子。由于重组外源蛋白的分泌效率提高，本发明对于提高酵母表达系统中重组外源蛋白质的生产力和生产成本的降低有所贡献。

9. 发明申请

US20110200679A1 METHOD FOR MANUFACTURING SUSTAINED RELEASE MICROSPHERE BY SOLVENT FLOW EVAPORATION METHOD 审中-公开
标题翻译：通过溶剂流动蒸发方法制造持续释放微球的方法
公开(公告)号：US20110200679A1
公开(公告)日：2011-08-18
申请号：US13061389
申请日：2009-08-28
申请人： Nak Hyun Lim , Sung Geun Kim , Se Yeon Kim , Hyung Joon Jung , Kyung Hoi Cha
发明人： Nak Hyun Lim , Sung Geun Kim , Se Yeon Kim , Hyung Joon Jung , Kyung Hoi Cha
IPC分类号： A61K9/14 , A61K38/09 , A61P5/24
CPC分类号： A61K9/1647 , A61K9/1694
摘要： The present invention relates to a method for preparing a sustained-release microsphere which can control the long-term release of a drug. More particularly, as the preparation of a microsphere in which a drug is loaded in a carrier comprising a biodegradable polymer, the present invention relates to a method for preparing a sustained-release microsphere wherein a solvent intra-exchange evaporation method by means of co-solvent is used for suppressing the initial burst release of physiologically active substance, to release the physiologically active substance in the body continuously and uniformly.
摘要翻译：本发明涉及可以控制药物长期释放的缓释微球的制备方法。更具体地，作为其中将药物负载在包含可生物降解的聚合物的载体中的微球的制备，本发明涉及一种制备缓释微球的方法，其中通过共 - 溶剂用于抑制生理活性物质的初始爆发释放，以连续均匀地释放身体中的生理活性物质。

10. 发明授权

US06237050B1 Method for controlling components of semiconductor fabricating equipment arranged in a processing line 失效
标题翻译：用于控制布置在处理线中的半导体制造设备的部件的方法
公开(公告)号：US06237050B1
公开(公告)日：2001-05-22
申请号：US09148631
申请日：1998-09-04
申请人： Sung-geun Kim , Tae-hyung Kim
发明人： Sung-geun Kim , Tae-hyung Kim
IPC分类号： G06F1310
CPC分类号： H01L22/20 , G05B19/4184 , G05B2219/31485 , Y02P90/14
摘要： A method for controlling equipment in a semiconductor fabrication system is provided. A host computer automatically receives actual data indicative of an actual state of a unit of equipment for fabricating semiconductor devices. The computer retrieves from a data base stored data indicative of a stored state of the unit. A state change is computed by comparing the actual data with the stored data and the state change is checked against a predetermined threshold. If the state change exceeds the threshold, the data base is updated by storing the actual data, and operation of the equipment is modified. If the state change does not exceed the threshold, the method returns to receiving actual data.
摘要翻译：提供了一种用于控制半导体制造系统中的设备的方法。主计算机自动接收指示用于制造半导体器件的设备单元的实际状态的实际数据。计算机从数据库检索存储表示该单元的存储状态的数据。通过将实际数据与存储的数据进行比较来计算状态改变，并且相对于预定阈值检查状态改变。如果状态变化超过阈值，则通过存储实际数据来更新数据库，并修改设备的操作。如果状态变化不超过阈值，则该方法返回接收实际数据。

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