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1. 发明授权

US08758274B2 Automated adjustment of posture state definitions for a medical device 有权
标题翻译：自动调整医疗器械的姿势状态定义
公开(公告)号：US08758274B2
公开(公告)日：2014-06-24
申请号：US12769431
申请日：2010-04-28
申请人： Rajeev M. Sahasrabudhe , Lynn Davenport , Jon P. Davis , Wende L. Dewing , Elizabeth A. Fehrmann , Steven Goetz , Shyam Gokaldas , Eric J. Panken
发明人： Rajeev M. Sahasrabudhe , Lynn Davenport , Jon P. Davis , Wende L. Dewing , Elizabeth A. Fehrmann , Steven Goetz , Shyam Gokaldas , Eric J. Panken
IPC分类号： A61B5/00
CPC分类号： A61B5/4839 , A61B5/021 , A61B5/024 , A61B5/0476 , A61B5/0488 , A61B5/1116 , A61B5/1118 , A61B5/14532 , A61B5/686 , A61B5/7264 , A61B5/7282 , A61B5/742 , A61B5/7475 , A61B2560/0223 , A61B2560/0475 , A61N1/36071 , A61N1/36535 , A61N1/37247 , G06F19/00 , G06F19/324 , G16H50/20
摘要： Techniques relate to operating a medical device by classifying a detected posture state of a patient. This classification may be performed by comparing the detected posture state of the patient to posture state definitions available within the system. Each definition may be described in terms of a parameter (e.g., vector) indicative of a direction in three-dimensional space. The posture state definitions may be calibrated by automatically estimating values for these parameters, thereby eliminating the need for the patient to assume each posture state during the calibration process to capture actual parameter values. According to another aspect, the estimated parameter values may be updated as the patient assumes various postures during a daily routine. For instance, estimated vectors initially used to calibrate the posture state definitions may be changed over time to more closely represent posture states the patient actually assumes, and to further adapt to changes in a patient's condition.
摘要翻译：技术涉及通过对检测到的患者的姿势状态进行分类来操作医疗装置。可以通过将检测到的患者的姿势状态与系统内可用的姿势状态定义进行比较来执行该分类。可以根据指示三维空间中的方向的参数（例如，矢量）来描述每个定义。可以通过自动估计这些参数的值来校准姿势状态定义，从而消除了在校准过程期间患者承担每个姿势状态以捕获实际参数值的需要。根据另一方面，当患者在日常例行程序中呈现各种姿势时，可以更新所估计的参数值。例如，最初用于校准姿势状态定义的估计矢量可以随着时间而改变以更加紧密地表示患者实际假定的姿势状态，并进一步适应患者状况的变化。

2. 发明申请

US20110172927A1 AUTOMATED ADJUSTMENT OF POSTURE STATE DEFINITIONS FOR A MEDICAL DEVICE 有权
标题翻译：自动调整医疗器械的姿态定义
公开(公告)号：US20110172927A1
公开(公告)日：2011-07-14
申请号：US12769431
申请日：2010-04-28
申请人： Rajeev M. Sahasrabudhe , Lynn Davenport , Jon P. Davis , Wende L. Dewing , Elizabeth A. Fehrmann , Steven Goetz , Shyam Gokaldas , Eric J. Panken
发明人： Rajeev M. Sahasrabudhe , Lynn Davenport , Jon P. Davis , Wende L. Dewing , Elizabeth A. Fehrmann , Steven Goetz , Shyam Gokaldas , Eric J. Panken
IPC分类号： G06F19/00
CPC分类号： A61B5/4839 , A61B5/021 , A61B5/024 , A61B5/0476 , A61B5/0488 , A61B5/1116 , A61B5/1118 , A61B5/14532 , A61B5/686 , A61B5/7264 , A61B5/7282 , A61B5/742 , A61B5/7475 , A61B2560/0223 , A61B2560/0475 , A61N1/36071 , A61N1/36535 , A61N1/37247 , G06F19/00 , G06F19/324 , G16H50/20
摘要： Techniques relate to operating a medical device by classifying a detected posture state of a patient. This classification may be performed by comparing the detected posture state of the patient to posture state definitions available within the system. Each definition may be described in terms of a parameter (e.g., vector) indicative of a direction in three-dimensional space. The posture state definitions may be calibrated by automatically estimating values for these parameters, thereby eliminating the need for the patient to assume each posture state during the calibration process to capture actual parameter values. According to another aspect, the estimated parameter values may be updated as the patient assumes various postures during a daily routine. For instance, estimated vectors initially used to calibrate the posture state definitions may be changed over time to more closely represent posture states the patient actually assumes, and to further adapt to changes in a patient's condition.
摘要翻译：技术涉及通过对检测到的患者的姿势状态进行分类来操作医疗装置。可以通过将检测到的患者的姿势状态与系统内可用的姿势状态定义进行比较来执行该分类。可以根据指示三维空间中的方向的参数（例如，矢量）来描述每个定义。可以通过自动估计这些参数的值来校准姿势状态定义，从而消除了在校准过程期间患者承担每个姿势状态以捕获实际参数值的需要。根据另一方面，当患者在日常例行程序中呈现各种姿势时，可以更新所估计的参数值。例如，最初用于校准姿势状态定义的估计矢量可以随着时间而改变以更加紧密地表示患者实际假定的姿势状态，并进一步适应患者状况的变化。

3. 发明申请

US20080015563A1 APPARATUS AND METHOD FOR CREATING, MAINTAINING, AND CONTROLLING A VIRTUAL ELECTRODE USED FOR THE ABLATION OF TISSUE 审中-公开
标题翻译：用于创建，维护和控制用于消除组织的虚拟电极的装置和方法
公开(公告)号：US20080015563A1
公开(公告)日：2008-01-17
申请号：US11782134
申请日：2007-07-24
申请人： Michael Hoey , Mark Christopherson , Steven Goetz
发明人： Michael Hoey , Mark Christopherson , Steven Goetz
IPC分类号： A61N1/00
CPC分类号： A61B18/18 , A61B18/1206 , A61B18/1233 , A61B18/14 , A61B18/1402 , A61B18/1815 , A61B2018/00029 , A61B2018/00196 , A61B2018/00666 , A61B2018/00678 , A61B2018/00702 , A61B2018/00708 , A61B2018/00779 , A61B2018/00791 , A61B2018/00797 , A61B2018/00821 , A61B2018/00875 , A61B2018/1213 , A61B2018/1253 , A61B2018/1417 , A61B2018/1472 , A61B2018/1475 , A61B2218/002 , A61B2218/007
摘要： An apparatus and a method for producing a virtual electrode within or upon a tissue to be treated with radio frequency alternating electric current. An apparatus in accord with the present disclosure includes a supply of a conductive or electrolytic fluid to be provided to the patient, an alternating current generator, and a processor for creating, maintaining, and controlling the ablation process by the interstitial or surficial delivery of the fluid to a tissue and the delivery of electric power to the tissue via the virtual electrode. A method in accord with the present disclosure includes delivering a conductive fluid to a predetermined tissue ablation site for a predetermined time period, applying a predetermined power level of radio frequency current to the tissue, monitoring at least one of several parameters, and adjusting either the applied power and/or the fluid flow in response to the measured parameters.
摘要翻译：一种在用射频交流电流处理的组织内或之上产生虚拟电极的装置和方法。根据本公开的装置包括提供要提供给患者的导电或电解液，交流发生器和用于通过间隔或表面递送的产生，维持和控制消融过程的处理器流体到组织并经由虚拟电极向组织递送电力。根据本公开的方法包括将导电流体递送到预定组织消融部位预定时间段，向组织施加预定功率水平的射频电流，监测几个参数中的至少一个，并且调整响应于测量的参数施加的功率和/或流体流量。

4. 发明申请

US20070213789A1 Global parameter adjustment for multiple stimulation programs 有权
标题翻译：多个刺激程序的全局参数调整
公开(公告)号：US20070213789A1
公开(公告)日：2007-09-13
申请号：US11372354
申请日：2006-03-09
申请人： Joseph Nolan , Ruth Bauhahn , Steven Goetz
发明人： Joseph Nolan , Ruth Bauhahn , Steven Goetz
IPC分类号： A61N1/36
CPC分类号： A61N1/37252
摘要： The disclosure describes a method and system that allows a user to modify a stimulation parameter in a plurality of stimulation programs with a single adjustment. During stimulation therapy, the user, such as a patient, may desire to change a parameter of the plurality of stimulation programs. The patient may press a single button on an external programmer to make the parameter change, or global adjustment, to all of the plurality of stimulation programs. This global adjustment eliminates the need for the patient to navigate through each of the plurality of stimulation programs separately and adjust the parameter. Additionally, changing the plurality of stimulation programs may be desirable for uniform stimulation therapy between programs used by the patient. The external programmer may calculate an appropriate parameter change for each stimulation program to keep parameter ratios equal between the plurality of stimulation programs.
摘要翻译：本公开描述了允许用户通过单次调整来修改多个刺激程序中的刺激参数的方法和系统。在刺激治疗期间，诸如患者的使用者可能希望改变多个刺激程序的参数。患者可以按压外部编程器上的单个按钮使参数改变或全局调整到所有多个刺激程序。这种全局调整消除了患者需要单独导航多个刺激程序中的每一个并调整参数。此外，改变多个刺激程序对于患者使用的程序之间的均匀刺激治疗可能是期望的。外部编程器可以计算每个刺激程序的适当参数变化，以保持多个刺激程序之间的参数比率相等。

5. 发明申请

US20060265025A1 Automatic lead functionality testing 审中-公开
标题翻译：自动引线功能测试
公开(公告)号：US20060265025A1
公开(公告)日：2006-11-23
申请号：US11414786
申请日：2006-04-28
申请人： Steven Goetz , Nathan Torgerson , Michael Lee
发明人： Steven Goetz , Nathan Torgerson , Michael Lee
IPC分类号： A61N1/00
CPC分类号： A61N1/37 , A61N1/36114 , A61N1/3706 , A61N2001/083
摘要： Techniques for performing lead functionality tests, e.g., lead impedance tests, for implantable electrical leads are described. In some of the described embodiments, an implantable medical device determines whether a patient is in a target activity state, e.g., an activity state in which lead impedance testing will be unobtrusive, such as when a patient is asleep, or capture information of particular interest, such as when the patient is active, in a particular posture, or changing postures. The implantable medical device performs the lead functionality test based on this determination. Additionally, in some embodiments, the implantable medical device may group a plurality of measurements for a single lead functionality test into a plurality of sessions, and perform the measurement sessions interleaved with delivery of therapeutic stimulation.
摘要翻译：描述了用于执行用于可植入电引线的引线功能测试（例如引线阻抗测试）的技术。在一些所描述的实施例中，可植入医疗设备确定患者是否处于目标活动状态，例如，其中导线阻抗测试将是不显眼的活动状态，例如当患者睡着时或捕获特定感兴趣的信息，例如当患者活跃时，处于特定姿势，或改变姿势。可植入医疗装置基于该确定执行引导功能测试。另外，在一些实施例中，可植入医疗装置可以将用于单个引线功能测试的多个测量分组成多个会话，并且执行与递送治疗性刺激交错的测量会话。

6. 发明申请

US20060265024A1 Distributed lead functionality testing 有权
公开(公告)号：US20060265024A1
公开(公告)日：2006-11-23
申请号：US11414536
申请日：2006-04-28
申请人： Steven Goetz , Nathan Torgerson , Michael Lee
发明人： Steven Goetz , Nathan Torgerson , Michael Lee
IPC分类号： A61N1/00
CPC分类号： A61N1/37 , A61N1/36114 , A61N1/3706 , A61N2001/083
摘要： Techniques for performing lead functionality tests, e.g., lead impedance tests, for implantable electrical leads are described. In some of the described embodiments, an implantable medical device determines whether a patient is in a target activity state, e.g., an activity state in which lead impedance testing will be unobtrusive, such as when a patient is asleep, or capture information of particular interest, such as when the patient is active, in a particular posture, or changing postures. The implantable medical device performs the lead functionality test based on this determination. Additionally, in some embodiments, the implantable medical device may group a plurality of measurements for a single lead functionality test into a plurality of sessions, and perform the measurement sessions interleaved with delivery of therapeutic stimulation.

7. 发明申请

US20060247710A1 Telemetry head programmer for implantable medical device and system and method 有权
标题翻译：用于植入式医疗设备的遥测头编程器及系统及方法
公开(公告)号：US20060247710A1
公开(公告)日：2006-11-02
申请号：US11119423
申请日：2005-04-29
申请人： Steven Goetz , Duane Bourget
发明人： Steven Goetz , Duane Bourget
IPC分类号： A61N1/362
CPC分类号： A61N1/37264 , A61N1/37211 , A61N1/37235 , A61N1/37247
摘要： System, telemetry head and method for programming an implantable medical device adapted to provide a therapeutic output to a patient, the implantable medical device being programmable through a telemetry interface. A telemetry head is adapted for transcutaneous communication with the implantable medical device through the telemetry interface when the telemetry head is positioned with respect to the implantable medical device. A computing device has computing processing power and a user interface linked with the telemetry head. The computing device processes the computing instructions associated with the implantable medical device. The computing device supplies the user interface based, at least in part, on the computing instructions associated with the implantable medical device. The telemetry head receives programming instructions from the computing device and provides the programming instructions to the implantable medical device using the transcutaneous telemetry interface.
摘要翻译：系统，遥测头和用于编程适于向患者提供治疗输出的可植入医疗装置的方法，所述可植入医疗装置可通过遥测接口进行编程。当遥测头相对于可植入医疗装置定位时，遥测头适于通过遥测接口与可植入医疗装置的经皮通信。计算设备具有与遥测头相连的计算处理能力和用户界面。计算设备处理与可植入医疗设备相关联的计算指令。所述计算设备至少部分地基于与所述可植入医疗设备相关联的计算指令来提供所述用户界面。遥测头从计算设备接收编程指令，并使用经皮遥测接口将编程指令提供给可植入医疗设备。

8. 发明申请

US20060195145A1 Identifying combinations of electrodes for neurostimulation therapy 审中-公开
公开(公告)号：US20060195145A1
公开(公告)日：2006-08-31
申请号：US11404069
申请日：2006-04-13
申请人： Michael Lee , Steven Goetz , Nathan Torgerson
发明人： Michael Lee , Steven Goetz , Nathan Torgerson
IPC分类号： A61N1/05 , A61N1/00
CPC分类号： A61N1/37247 , A61N1/36082 , A61N1/36185 , Y10S128/903
摘要： A programmer allows a clinician to identify combinations of electrodes from within an electrode set implanted in a patient that enable delivery of desirable neurostimulation therapy by an implantable medical device. The programmer executes an electrode combination search algorithm to select combinations of electrodes to test in a non-random order. According to algorithms consistent with the invention, the programmer may first identify a position of a first cathode for subsequent combinations, and then select electrodes from the set to test with the first cathode as anodes or additional cathodes based on the proximity of the electrodes to the first cathode. The programmer may store information for each combination tested, and the information may facilitate the identification of desirable electrode combinations by the clinician. The clinician may create neurostimulation therapy programs that include identified desirable program combinations.

9. 发明申请

US20060155333A1 Human-implantable-neurostimulator user interface having multiple levels of abstraction 有权
公开(公告)号：US20060155333A1
公开(公告)日：2006-07-13
申请号：US11371868
申请日：2006-03-09
申请人： Steven Goetz
发明人： Steven Goetz
IPC分类号： A61N1/00
CPC分类号： A61N1/37252 , A61N1/08 , A61N1/36071 , A61N1/37247
摘要： A programming-device user interface may include multiple levels of abstraction for programming treatment settings. A stimulation zone-programming interface may be at a highest level of abstraction and may include idealized stimulation zones. A field strength-programming interface may be at a middle level of abstraction and may include electromagnetic field-strength patterns generated by the stimulation zones, and/or electrode settings, and a depiction of how the electromagnetic fields interact with each other. An electrode-programming interface may be at a lowest level of abstraction and may depict treatment settings at an electrodes-view level. These interfaces may include a display of a stimulatable area of the patient's body. The display may include a depiction of leads and/or the underlying physiology, such as a depiction of a portion of a spine. Algorithms map treatment settings from one level of abstraction to settings at one or more other levels of abstraction.

10. 发明申请

US20060036186A1 Automated impedance measurement of an implantable medical device 有权
标题翻译：可植入医疗器械的自动阻抗测量
公开(公告)号：US20060036186A1
公开(公告)日：2006-02-16
申请号：US11253391
申请日：2005-10-19
申请人： Steven Goetz , Jordan Barnhorst , James Hartmann
发明人： Steven Goetz , Jordan Barnhorst , James Hartmann
IPC分类号： A61B5/05
CPC分类号： A61N1/08 , A61N2001/083
摘要： Aspects of the present invention relate to automatic impedance measurements between one or more electrodes in a set of electrodes that may be associated with a lead of an implanted device. A voltage measurement that is associated with a stimulation pulse between the two electrodes may be made. The voltage measurement may be used to determine the impedance between the two electrodes. The impedance measurement may be made for each possible pair of electrodes in the set of electrodes. The impedance measurements may be displayed to a clinician on a user interface.
摘要翻译：本发明的方面涉及可以与植入装置的引线相关联的一组电极中的一个或多个电极之间的自动阻抗测量。可以进行与两个电极之间的刺激脉冲相关联的电压测量。电压测量可用于确定两个电极之间的阻抗。可以对该组电极中的每对可能的电极进行阻抗测量。阻抗测量可以在用户界面上向临床医生显示。

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