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1. 发明授权

US4855230A Microorganism inhibition of frost damage to plants 失效
标题翻译：微生物抑制霜冻对植物的伤害
公开(公告)号：US4855230A
公开(公告)日：1989-08-08
申请号：US110557
申请日：1987-10-19
申请人： Steven E. Lindow
发明人： Steven E. Lindow
IPC分类号： A01N63/00
CPC分类号： A01N63/00 , Y10S435/847 , Y10S435/874 , Y10S435/876
摘要： Plant host acceptable microorganisms, which are ice nucleation deficient and use at least one nutrient from the plant also used by ice nucleating native microorganisms, are applied to a plant part at an early stage in the growth cycle. The multiplication of the native ice nucleating microorganisms is inhibited, so that under normal frost conditions encountered in the field, frost damage is substantially diminished. The non-nucleating microorganisms may be obtained by special selection procedures, selecting from naturally occuring microorganisms or mutagenized microorganisms, where additionally the organisms may be transformed to provide for other desirable properties.
摘要翻译：在生长周期的早期阶段，将植物宿主可接受的微生物（其是冰成核缺陷的，并且还使用来自植物的至少一种营养物也被冰成核天然微生物使用）施用于植物部分。天然冰成核微生物的增殖被抑制，使得在现场遇到的正常霜冻条件下，霜冻损伤明显降低。非成核微生物可以通过特殊选择方法获得，从天然存在的微生物或诱变微生物中选择，其中另外可以转化生物体以提供其它所需的性质。

2. 发明授权

US4636386A Mycological method for controlling italian thistle growth 失效
标题翻译：用于控制意大利蓟生长的真菌学方法
公开(公告)号：US4636386A
公开(公告)日：1987-01-13
申请号：US643214
申请日：1984-08-22
申请人： Gary L. Anderson , Steven E. Lindow
发明人： Gary L. Anderson , Steven E. Lindow
IPC分类号： A01N63/04 , A01N63/00 , C12N1/00 , C12R1/645
CPC分类号： C12R1/645 , A01N63/04 , Y10S435/911
摘要： A novel pathovar has been isolated and purified, which pathovar most resembles Alternaria zinniae Pape, but has a host specificity for Italian thistle. By administering spores of this pathovar, called Alternaria sp., particularly shortly after emergence, Italian thistle growth is substantially inhibited.The spores of Alternaria sp. described in the subject invention have been deposited at the A.T.C.C. on Aug. 17, 1984 and given Accession No. 20723.
摘要翻译：已经分离和纯化了一种新型病原体，其病原体最类似于链格孢（Alternaria zinniae Pape），但对意大利蓟具有宿主特异性。通过施用这种称为链格孢属的病原体的孢子，特别是在出苗后不久，意大利蓟生长被显着抑制。链格孢属孢子本发明描述的方法已经存于A.T.C.C. 1984年8月17日，加拿大号20723。

3. 发明授权

US4464473A Ice nucleating microorganisms 失效
标题翻译：冰成核微生物
公开(公告)号：US4464473A
公开(公告)日：1984-08-07
申请号：US371162
申请日：1982-04-23
申请人： Cindy S. Orser , Steven E. Lindow , Nickolas J. Panopoulos , Brian J. Staskawicz
发明人： Cindy S. Orser , Steven E. Lindow , Nickolas J. Panopoulos , Brian J. Staskawicz
IPC分类号： C07H21/04 , C07K14/21 , C07K14/27 , C12N20060101 , C12N1/00 , C12N1/20 , C12N5/00 , C12N15/00 , C12N15/31 , C12N15/70 , F25C1/00 , F25C3/04 , C12P21/00
CPC分类号： F25C3/04 , C07K14/21 , C07K14/27 , C12N15/70 , F25C1/00 , F25C2303/044
摘要： DNA sequences encoding for ice nucleation activity are isolated and introduced into unicellular hosts. The modified hosts demonstrate ice nucleation activity analogous to the DNA source host. The cellular products find use in inhibiting supercooling.
摘要翻译：分离编码冰核活性的DNA序列并将其引入单细胞宿主体内。修饰的宿主证明类似于DNA源宿主的冰核活动。蜂窝产品用于抑制过冷。

4. 发明授权

US08247648B2 Biological control of pathogenicity in microbes that use alpha, beta unsaturated fatty acid signal molecules 有权
标题翻译：使用α，β不饱和脂肪酸信号分子的微生物中的致病性的生物学控制
公开(公告)号：US08247648B2
公开(公告)日：2012-08-21
申请号：US12422825
申请日：2009-04-13
申请人： Karyn L. Newman , Steven E. Lindow
发明人： Karyn L. Newman , Steven E. Lindow
IPC分类号： C12N15/09 , C12N15/82 , C12N15/31 , A01H5/00
CPC分类号： C12N9/00 , A01N37/46 , A01N63/00 , C12N15/8279 , C12N15/8281 , A01N25/04 , A01N25/12 , A01N2300/00
摘要： DSF-based microbial pathogens may be controlled by certain methods and compositions. A method of controlling diseases caused in a host organism by pathogenic microbial expression of α,β unsaturated fatty acid signal (DSF) molecules involves inoculating the host organism with a non-pathogenic microbe that disrupts α,β unsaturated fatty acid signal molecule-mediated cell-cell communication by the pathogenic microbe in the host organism. Microbes having protein expression that interferes with α,β unsaturated fatty acid signal molecule-mediated cell-cell communication by the pathogenic microbe in the host organism can be identified and isolated or engineered by transformation with DSF-interference (inhibition or activation) gene or genes. Genes conferring DSF-interference activity can also be expressed in organisms (e.g., plants) susceptible to diseases caused by microbes that use DSF, resulting in genetically resistant organisms.
摘要翻译：基于DSF的微生物病原体可以通过某些方法和组合物来控制。通过α，bgr的致病微生物表达来控制宿主生物体内引起的疾病的方法。不饱和脂肪酸信号（DSF）分子涉及用非致病微生物接种宿主生物，其破坏α和bgr; 不饱和脂肪酸信号分子介导的细胞通过宿主生物体中的致病微生物进行通讯。具有干扰α，bgr的蛋白质表达的微生物通过用DSF干扰（抑制或激活）基因或基因转化，可以鉴定并分离或工程化通过宿主生物体中致病微生物的不饱和脂肪酸信号分子介导的细胞 - 细胞通信。赋予DSF干扰活性的基因也可以在对使用DSF的微生物引起的疾病敏感的生物（例如植物）中表达，导致遗传抗性生物体。

5. 发明申请

US20090227028A1 BIOLOGICAL CONTROL OF PATHOGENICITY IN MICROBES THAT USE ALPHA, BETA UNSATURATED FATTY ACID SIGNAL MOLECULES 有权
标题翻译：使用ALPHA，BETA不饱和脂肪酸信号分子的微生物的致病性生物学控制
公开(公告)号：US20090227028A1
公开(公告)日：2009-09-10
申请号：US12422825
申请日：2009-04-13
申请人： Karyn L. Newman , Steven E. Lindow
发明人： Karyn L. Newman , Steven E. Lindow
IPC分类号： C12N5/10
CPC分类号： C12N9/00 , A01N37/46 , A01N63/00 , C12N15/8279 , C12N15/8281 , A01N25/04 , A01N25/12 , A01N2300/00
摘要： DSF-based microbial pathogens may be controlled by certain methods and compositions. A method of controlling diseases caused in a host organism by pathogenic microbial expression of α,β unsaturated fatty acid signal (DSF) molecules involves inoculating the host organism with a non-pathogenic microbe that disrupts α,β unsaturated fatty acid signal molecule-mediated cell-cell communication by the pathogenic microbe in the host organism. Microbes having protein expression that interferes with α,β unsaturated fatty acid signal molecule-mediated cell-cell communication by the pathogenic microbe in the host organism can be identified and isolated or engineered by transformation with DSF-interference (inhibition or activation) gene or genes. Genes conferring DSF-interference activity can also be expressed in organisms (e.g., plants) susceptible to diseases caused by microbes that use DSF, resulting in genetically resistant organisms.
摘要翻译：基于DSF的微生物病原体可以通过某些方法和组合物来控制。通过α，β不饱和脂肪酸信号（DSF）分子的致病微生物表达来控制在宿主生物体中引起的疾病的方法包括用破坏α，β不饱和脂肪酸信号分子介导的细胞的非致病微生物接种宿主生物体通过宿主生物体中的致病微生物进行细胞通讯。具有干扰α，β不饱和脂肪酸信号分子介导的细胞间通过宿主生物体中的致病微生物的蛋白质表达的微生物可以通过用DSF干扰（抑制或激活）基因或基因转化来鉴定和分离或工程化。赋予DSF干扰活性的基因也可以在对使用DSF的微生物引起的疾病敏感的生物（例如植物）中表达，导致遗传抗性生物体。

6. 发明授权

US4877438A Microbial and chemical control of fruit russetting 失效
标题翻译：水果俄罗斯的微生物和化学防治
公开(公告)号：US4877438A
公开(公告)日：1989-10-31
申请号：US80707
申请日：1987-08-03
申请人： Steven E. Lindow
发明人： Steven E. Lindow
IPC分类号： A01N63/00
CPC分类号： A01N63/00
摘要： A method is provided of reducing fruit russetting by treating the surface of a fruit to reduce the amount of auxins present on the surface. In a preferred embodiment, the population of auxin-producing bacteria is reduced by providing a competing auxin-deficient bacterial population.

7. 发明授权

US4432160A Microrganism inhibition of frost damage to plants 失效
标题翻译：微生物抑制对植物的霜冻伤害
公开(公告)号：US4432160A
公开(公告)日：1984-02-21
申请号：US294604
申请日：1981-08-20
申请人： Steven E. Lindow
发明人： Steven E. Lindow
IPC分类号： A01G7/00 , A01G13/00 , A01N63/00 , B01D53/34 , C12N1/20 , A01G1/00
CPC分类号： A01N63/00
摘要： Plant host acceptable microorganisms, which are ice nucleation deficient and use at least one nutrient from the plant also used by ice nucleating native microorganisms, are applied to a plant part at an early stage in the growth cycle. The multiplication of the native ice nucleating microorganisms is inhibited, so that under normal frost conditions encountered in the field, frost damage is substantially diminished. The non-nucleating microorganisms may be obtained by special selection procedures, selecting from naturally occurring microorganisms or mutagenized microorganisms, where additionally the organisms may be transformed to provide for other desirable properties.The following organisms have been deposited at the A.T.C.C. on Aug. 13, 1981; A5-01, A5-05-1, A5-06, A5-10-1, A5-26, and A4-2B-10.
摘要翻译：在生长周期的早期阶段，将植物宿主可接受的微生物（其是冰成核缺陷的，并且还使用来自植物的至少一种营养物也被冰成核天然微生物使用）施用于植物部分。天然冰成核微生物的增殖被抑制，使得在现场遇到的正常霜冻条件下，霜冻损伤明显降低。非成核微生物可以通过特殊选择方法获得，从天然存在的微生物或诱变微生物中选择，此外还可以转化生物以提供其它所需的性质。以下生物已经存放在A.T.C.C. 1981年8月13日; A5-01，A5-05-1，A5-06，A5-10-1，A5-26和A4-2B-10。

8. 发明授权

US4161084A Method for reducing temperature at which plants freeze 失效
标题翻译：降低植物冻结温度的方法
公开(公告)号：US4161084A
公开(公告)日：1979-07-17
申请号：US921800
申请日：1978-07-03
申请人： Deane C. Arny , Steven E. Lindow
发明人： Deane C. Arny , Steven E. Lindow
IPC分类号： A01G13/00 , A01N63/00 , A01G1/00
CPC分类号： A01N63/00 , A01G13/00
摘要： The method for reducing the temperature at which freezing takes place in plants to reduce frost damage by the addition of non-ice nucleating bacteria to the plants prior to the onset of freezing temperature and preferably while the plants are in their seedling stage.
摘要翻译：减少在植物中发生冷冻的温度的方法，以在冷冻温度开始之前，优选在植物处于其苗期期间，通过向植物中加入非冰成核细菌来减少霜冻损伤。

9. 发明授权

US4045910A Method for reducing frost damage of plants 失效
标题翻译：减少植物霜冻伤害的方法
公开(公告)号：US4045910A
公开(公告)日：1977-09-06
申请号：US710414
申请日：1976-08-02
申请人： Deane C. Arny , Steven E. Lindow
发明人： Deane C. Arny , Steven E. Lindow
IPC分类号： A01G13/00 , A01N63/00 , A01G1/00
CPC分类号： A01N63/00 , A01G13/00 , Y10S435/847
摘要： The protection of plants against frost damage comprising treating the plants before the onset of freezing cold with bacterium M232A.
摘要翻译：保护植物免受霜冻伤害，包括在用细菌M232A冷冻开始之前对植物进行处理。

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