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    • 1. 发明授权
    • Method and device for measuring systolic and diastolic blood pressure and heart rate in an environment with extreme levels of noise and vibrations
    • 在具有极高噪声和振动水平的环境中测量收缩压和舒张压和心率的方法和装置
    • US06805671B2
    • 2004-10-19
    • US10342277
    • 2003-01-15
    • Stergios StergiopoulosAmar DhanantwariLisa PintoRonald ZachariahMan Yee Winnie Wong
    • Stergios StergiopoulosAmar DhanantwariLisa PintoRonald ZachariahMan Yee Winnie Wong
    • A61B502
    • A61B5/02208A61B5/025A61B7/045
    • A method and a device for measuring blood pressure and heart rate in an environment comprising extreme levels of noise and vibrations is disclosed. Blood pressure signals corresponding to the Korotkoff sounds are detected using an array of primary acoustic sensors, placed on the patient's skin over the brachial artery. A secondary acoustic transducer is placed on the outside of a pressure cuff the patient away for detecting noise and vibrations. Pressure is applied to the artery using the pressure cuff forcing the artery to close. The pressure is then reduced and while reducing the pressure the acoustic signals detected by the first and second acoustic sensor as well as a signal indicative of the pressure applied to the artery are provided to a processor. The signals provided by the primary acoustic sensors are then processed using a combination of focused beamforming and planar wave beamforming. The final beam time series is then processed using an adaptive interferer canceller algorithm with the signal provided by the secondary acoustic sensor as interferer. Use of an array of acoustic sensors in combination with beamforming substantially enhances signal detection as well as accurate isolation of the signal source which is highly beneficial for blood pressure measurements measurements performed under extreme levels of noise and vibrations.
    • 公开了一种用于在包括极高水平的噪声和振动的环境中测量血压和心率的方法和装置。 使用放置在肱动脉上的患者皮肤上的主要声学传感器阵列来检测对应于Korotkoff声音的血压信号。 辅助声换能器放置在患者远离的压力袖带的外侧,用于检测噪声和振动。 使用压力袖带迫使动脉闭合,向动脉施加压力。 然后降低压力并且在降低压力的同时,将由第一和第二声学传感器检测的声学信号以及指示施加到动脉的压力的信号提供给处理器。 然后,使用聚焦波束形成和平面波束形成的组合来处理由主声传感器提供的信号。 然后使用自适应干扰消除器算法来处理最终光束时间序列,其中由第二声传感器提供的信号作为干扰源。 使用声波传感器阵列与波束成形技术相结合,可显着增强信号检测以及信号源的准确隔离,这对于在极高噪声和振动水平下进行的血压测量测量非常有益。
    • 2. 发明授权
    • High resolution 3D ultrasound imaging system deploying a multidimensional array of sensors and method for multidimensional beamforming sensor signals
    • 高分辨率3D超声成像系统部署了多维传感器阵列和多维波束成形传感器信号的方法
    • US06482160B1
    • 2002-11-19
    • US09718516
    • 2000-11-24
    • Stergios StergiopoulosAmar C. Dhanantwari
    • Stergios StergiopoulosAmar C. Dhanantwari
    • A61B800
    • G01S15/8927G01S7/52046G01S15/8929G01S15/8993G10K11/346Y10S128/916
    • An adaptive multidimensional beamformer having near-instantaneous convergence for ultrasound imaging systems deploying multidimensional sensor arrays is disclosed. In a first step, the multidimensional beamformer is decomposed into sub-apertures. Each sub-aperture is then again decomposed into two coherent subsets of circular and/or line array beamformers in different coordinate directions of the multidimensional array. Implementation of the multidimensional beamformer according to the present invention provides the basis for a 3D ultrasound imaging system according to the present invention comprising a compact multidimensional sensor array and a compact processing unit that is field deployable and generates high resolution three-dimensional images in real time. It is also possible to capture four-dimensional images, the fourth dimension being time and the resulting images forming a video image of a volume of a moving organ.
    • 公开了一种对于部署多维传感器阵列的超声成像系统具有近瞬间会聚的自适应多维波束形成器。 在第一步骤中,多维波束形成器被分解为子孔径。 然后,每个子孔径再分解成在多维阵列的不同坐标方向上的圆形和/或线阵列波束形成器的两个相干子集。 根据本发明的多维波束形成器的实现为根据本发明的3D超声波成像系统提供了基础,其包括紧凑的多维传感器阵列和紧凑的处理单元,该处理单元是现场可部署的并且实时生成高分辨率三维图像 。 也可以捕获四维图像,第四维是时间,并且所得到的图像形成移动器官的体积的视频图像。
    • 4. 发明申请
    • Method and device for measuring systolic and diastolic blood pressure and heart rate
    • 测量收缩压和舒张压和心率的方法和装置
    • US20060253040A1
    • 2006-11-09
    • US11356958
    • 2006-02-21
    • Stergios StergiopoulosDimitrios Hatzinakos
    • Stergios StergiopoulosDimitrios Hatzinakos
    • A61B5/02
    • A61B5/02208A61B5/7207A61B5/7239A61B7/045
    • A method and a device for measuring blood pressure and heart rate is disclosed. Blood pressure signals corresponding to the Korotkoff sounds are detected using an array of primary acoustic sensors. A secondary acoustic sensor is used for detecting noise and vibrations. The signals provided by the primary acoustic sensors are then processed using adaptive linear beamforming and are combined into a single signal. The combined signal is then provided to an adaptive interferer canceller together with the signal of the secondary acoustic sensor for removing noise and vibration effects. Artifacts due to a patient's motion are removed in a following post-processing step. The post-processed signal and the pressure signal are then graphically displayed enabling a trained user to correct the automatic measurement, to decide whether a repeat measurement is necessary, and to quickly and accurately diagnose heart pulse patterns.
    • 公开了一种用于测量血压和心率的方法和装置。 使用主要声学传感器阵列来检测对应于Korotkoff声音的血压信号。 二次声传感器用于检测噪声和振动。 然后由主要声学传感器提供的信号使用自适应线性波束形成进行处理,并且被组合成单个信号。 然后将组合的信号与辅助声传感器的信号一起提供给自适应干扰消除器,以消除噪声和振动效应。 在后续处理步骤中移除由于患者运动引起的人工制品。 后处理信号和压力信号然后被图形显示,使训练有素的用户能够校正自动测量,以确定是否需要重复测量,以及快速准确地诊断心脏脉搏模式。
    • 5. 发明授权
    • High resolution 3D ultrasound imaging system deploying a multi-dimensional array of sensors and method for multi-dimensional beamforming sensor signals
    • 高分辨率3D超声成像系统部署了多维传感器阵列和多维波束成形传感器信号的方法
    • US06719696B2
    • 2004-04-13
    • US10273951
    • 2002-10-21
    • Stergios StergiopoulosAmar C. Dhanantwari
    • Stergios StergiopoulosAmar C. Dhanantwari
    • A61B800
    • G01S15/8927G01S7/52046G01S15/8929G01S15/8993G10K11/346Y10S128/916
    • An adaptive multidimensional beamformer having near-instantaneous convergence for ultrasound imaging systems deploying multidimensional sensor arrays is disclosed. In a first step, the multidimensional beamformer is decomposed into sub-apertures. Each sub-aperture is then again decomposed into two coherent subsets of circular and/or line array beamformers in different coordinate directions of the multidimensional array. Implementation of the multidimensional beamformer according to the present invention provides the basis for a 3D ultrasound imaging system according to the present invention comprising a compact multidimensional sensor array and a compact processing unit that is field deployable and generates high resolution three-dimensional images in real time. It is also possible to capture four-dimensional images, the fourth dimension being time and the resulting images forming a video image of a volume of a moving organ.
    • 公开了一种对于部署多维传感器阵列的超声成像系统具有近瞬间会聚的自适应多维波束形成器。 在第一步骤中,多维波束形成器被分解为子孔径。 然后,每个子孔径再分解成在多维阵列的不同坐标方向上的圆形和/或线阵列波束形成器的两个相干子集。 根据本发明的多维波束形成器的实现为根据本发明的3D超声波成像系统提供了基础,其包括紧凑的多维传感器阵列和紧凑的处理单元,该处理单元是可现场部署的并且实时生成高分辨率三维图像 。 也可以捕获四维图像,第四维是时间,并且所得到的图像形成移动器官的体积的视频图像。
    • 6. 发明授权
    • Method and device for measuring systolic and diastolic blood pressure and heart rate in an environment with extreme levels of noise and vibrations
    • 在具有极高噪声和振动水平的环境中测量收缩压和舒张压和心率的方法和装置
    • US06705998B2
    • 2004-03-16
    • US10133575
    • 2002-04-29
    • Stergios StergiopoulosAmar DhanantwariLisa PintoRonald Zachariah
    • Stergios StergiopoulosAmar DhanantwariLisa PintoRonald Zachariah
    • A61B502
    • A61B5/02208A61B5/022A61B5/025A61B7/045
    • A method and a device for measuring systolic and diastolic blood pressure and heart rate in an environment comprising extreme levels of noise and vibrations is disclosed. Blood pressure signals corresponding to the Korotkoff sounds are detected using a first acoustic sensor, or array of sensors, placed on the patient's skin over the brachial artery. A second acoustic transducer is placed on the outside of a pressure cuff the patient away for detecting noise and vibrations. Pressure is applied to the artery using the pressure cuff forcing the artery to close. The pressure is then reduced and while reducing the pressure the acoustic signals detected by the first and second acoustic sensor as well as a signal indicative of the pressure applied to the artery are provided to a processor. The signal of the first acoustic sensor is then processed using an adaptive interferer canceller algorithm with the signal of the second acoustic sensor as interferer. From the processed signal heart beat pulses are determined and relating the heart beat pulses to the pressure signal provides the systolic and diastolic blood pressure. Use of the adaptive interferer canceller provides good results for measurements performed under extreme levels of noise and vibrations such as aboard a helicopter, naval vessels, ambulances and noisy emergency rooms.
    • 公开了一种用于在包括极端噪声和振动的环境中测量收缩和舒张压和心率的方法和装置。 使用放置在肱动脉上的患者皮肤上的第一声传感器或传感器阵列检测对应于Korotkoff声音的血压信号。 将第二声换能器放置在患者远离的压力袖带的外侧以检测噪声和振动。 使用压力袖带迫使动脉闭合,向动脉施加压力。 然后降低压力并且在降低压力的同时,将由第一和第二声学传感器检测的声学信号以及指示施加到动脉的压力的信号提供给处理器。 然后使用具有第二声传感器的信号作为干扰源的自适应干扰消除器算法来处理第一声传感器的信号。 从经处理的信号中,确定心搏脉冲并将心跳脉搏与压力信号相关联,提供收缩压和舒张压。 自适应干扰消除器的使用对于在诸如直升机,海军舰艇,救护车和嘈杂的急诊室之间的极端噪音和振动水平下进行的测量提供了良好的结果。
    • 7. 发明授权
    • Method and device for measuring systolic and diastolic blood pressure and heart rate in an environment with extreme levels of noise and vibrations
    • 在具有极高噪声和振动水平的环境中测量收缩压和舒张压和心率的方法和装置
    • US06520918B1
    • 2003-02-18
    • US09718515
    • 2000-11-24
    • Stergios StergiopoulosAmar C. Dhanantwari
    • Stergios StergiopoulosAmar C. Dhanantwari
    • A61B502
    • A61B7/045A61B5/022A61B5/025
    • A method and a device for measuring systolic and diastolic blood pressure and heart rate in an environment comprising extreme levels of noise and vibrations is disclosed. Blood pressure signals corresponding to the heart beat are detected using a first acoustic sensor placed on a patient near an artery. A second acoustic transducer is placed on the patient away from the artery for detecting noise and vibrations. Pressure is applied to the artery forcing the artery to close. The pressure is then reduced and while reducing the pressure the acoustic signals detected by the first and second acoustic sensor as well as a signal indicative of the pressure applied to the artery are provided to a processing unit. The signal of the first acoustic sensor is then processed using an adaptive interferer canceller algorithm with the signal of the second acoustic sensor as interferer. From the processed signal heart beat pulses are determined and relating the heart beat pulses to the pressure signal provides the systolic and diastolic blood pressure. Use of the adaptive interferer canceller provides good results for measurements performed under extreme levels of noise and vibrations such as aboard a helicopter.
    • 公开了一种用于在包括极端噪声和振动的环境中测量收缩和舒张压和心率的方法和装置。 使用放置在动脉附近的患者上的第一声学传感器来检测对应于心跳的血压信号。 将第二声换能器放置在远离动脉的患者身上,以便检测噪声和振动。 对动脉施加压力以迫使动脉闭合。 然后降低压力并且在减小压力的同时,将由第一和第二声学传感器检测的声学信号以及指示施加到动脉的压力的信号提供给处理单元。 然后使用具有第二声传感器的信号作为干扰源的自适应干扰消除器算法来处理第一声传感器的信号。 从经处理的信号中,确定心搏脉冲并将心跳脉搏与压力信号相关联,提供收缩压和舒张压。 自适应干扰消除器的使用对于在诸如直升机之类的极端噪声和振动水平下进行的测量提供了良好的结果。
    • 10. 发明申请
    • Method and system for blind reconstruction of multi-frame image data
    • 多帧图像数据盲目重建的方法和系统
    • US20070031058A1
    • 2007-02-08
    • US11442992
    • 2006-05-31
    • Dimitrios HatzinakosStergios Stergiopoulos
    • Dimitrios HatzinakosStergios Stergiopoulos
    • G06K9/40G06K9/36
    • G06T5/50G06T3/4076G06T5/003
    • The present invention relates to a method for blind reconstruction of multi-frame image data. Multi-frame image data corresponding to at least two image frames are received. Using a filter function the image data corresponding to each of the at least two image frames are filtered. The filtered image data are then classified producing data indicative of a classified image for each of the at least two image frames. In a following step the filtered image data are fusion-based classified producing data indicative of a classified fused image. By superposing the corresponding data indicative of the classified image with the data indicative of the classified fused image an error function is determined for each of the at least two image frames. Using the error function the filter function for each of the at least two image frames is then updated. This process is repeated until a stopping criterion is met. After stopping the iteration reconstructed image data based on the filtered image data of at least one of the at least two image frames are provided.
    • 本发明涉及一种多帧图像数据盲目重建的方法。 接收对应于至少两个图像帧的多帧图像数据。 使用滤波器功能,对与至少两个图像帧中的每一个对应的图像数据进行滤波。 然后对滤波后的图像数据进行分类,产生指示至少两个图像帧中的每一个的分类图像的数据。 在随后的步骤中,滤波图像数据是基于融合的分类产生表示分类融合图像的数据。 通过将指示分类图像的相应数据与指示分类的融合图像的数据叠加,为至少两个图像帧中的每一个确定误差函数。 然后使用错误功能,更新至少两个图像帧中的每一个的过滤器功能。 重复该过程,直到满足停止标准。 在提供基于至少两个图像帧中的至少一个的滤波图像数据停止迭代重构图像数据之后。