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1. 发明授权

US10029122B2 Charged particle—patient motion control system apparatus and method of use thereof 有权
公开(公告)号：US10029122B2
公开(公告)日：2018-07-24
申请号：US15176025
申请日：2016-06-07
申请人： Susan L. Michaud , Stephen L. Spotts , James P. Bennett , W. Davis Lee
发明人： Susan L. Michaud , Stephen L. Spotts , James P. Bennett , W. Davis Lee
IPC分类号： A61N5/00 , A61N5/10 , G21K5/04 , A61B6/03 , A61B6/00 , G21K1/08
摘要： The invention comprises a system for controlling a charged particle beam shape and direction relative to a controlled and dynamically positioned patient and/or an imaging surface, such as a scintillation plate of a tomography system and/or a first two-dimensional imaging system coupled to a second two-dimensional imaging system. Multiple interlinked beam/patient/imaging control stations allow safe zone operation and clear interaction with the charged particle beam system and the patient. Both treatment and imaging are facilitated using automated sequences controlled with a work-flow control system.

2. 发明申请

US20180169441A1 CANCER THERAPY TREATMENT BEAM / SCANNING CONTROL APPARATUS AND METHOD OF USE THEREOF 审中-公开
公开(公告)号：US20180169441A1
公开(公告)日：2018-06-21
申请号：US15892282
申请日：2018-02-08
申请人： Stephen L. Spotts , W. Davis Lee
发明人： Stephen L. Spotts , W. Davis Lee
IPC分类号： A61N5/10 , G21K1/087 , G21K5/04 , A61B6/03 , G21K1/093 , H01J35/14
CPC分类号： A61N5/1077 , A61B6/03 , A61B6/032 , A61B6/037 , A61B6/4085 , A61N5/103 , A61N5/1043 , A61N5/1044 , A61N5/1049 , A61N5/1067 , A61N5/107 , A61N5/1081 , A61N5/1082 , A61N2005/1061 , A61N2005/1074 , A61N2005/1087 , A61N2005/1097 , G21K1/087 , G21K1/093 , G21K5/04 , G21K5/10 , H01J35/14
摘要： The invention comprises a method and apparatus for controlling tumor treatment, comprising the steps of: (1) a control system controlling a cancer therapy system, the control system comprising a set of modular control units, the cancer therapy system comprising a set of subsystem elements, (2) altering a first subsystem of the set of subsystem elements; and (3) updating a first modular control unit, of the set of modular control units, corresponding to the first subsystem without a necessitated change of remaining code elements of the set of modular control units corresponding to non-altered subsystem elements of the set of subsystem elements with an optional step of altering main subsystem controller code configured to control the set of subsystem control modules. Optionally the control system directly controls each of the subsystem elements and/or communicates with each of the set of subsystem elements without direct communication between the set of subsystem elements.

3. 发明授权

US10118052B2 Charged particle cancer therapy installation system 有权
公开(公告)号：US10118052B2
公开(公告)日：2018-11-06
申请号：US15727596
申请日：2017-10-07
申请人： Stephen L. Spotts , James P. Bennett , W. Davis Lee
发明人： Stephen L. Spotts , James P. Bennett , W. Davis Lee
IPC分类号： A61N5/10 , G21K5/04 , A61N5/01
摘要： The invention comprises a method for installing a proton based cancer therapy system in a hospital related brownfield building, comprising the steps of: (1) transporting gantry system elements to a basement of the brownfield, the gantry system comprising: a rotatable gantry support; a gantry counterweight; a rotatable gantry arm, and a main bearing, comprising: a diameter of at least ten feet, a first circular segment, comprising a first arc-to-chord section, a second circular segment, comprising a second arc-to-chord section, and an intermediate section; (2) transporting through a pre-existing elevator shaft in the hospital related brownfield building the main bearing in a disassembled form; and (3) after the step of transporting through the pre-existing elevator shaft, assembling the gantry system on the ground floor, the step of assembling comprising attaching the first circular segment of the main bearing to the second circular segment of the main bearing using the intermediate section.

4. 发明申请

US20180161601A1 AUTOMATED CANCER THERAPY TREATMENT BEAM / SCANNING APPARATUS AND METHOD OF USE THEREOF 审中-公开
公开(公告)号：US20180161601A1
公开(公告)日：2018-06-14
申请号：US15892240
申请日：2018-02-08
申请人： Stephen L. Spotts , W. Davis Lee
发明人： Stephen L. Spotts , W. Davis Lee
IPC分类号： A61N5/10 , G21K1/087 , G21K5/04 , A61B6/03 , G21K1/093 , H01J35/14
CPC分类号： A61N5/1077 , A61B6/00 , A61B6/03 , A61B6/032 , A61B6/4258 , A61B6/5205 , A61N5/1037 , A61N5/1039 , A61N5/1044 , A61N5/1049 , A61N5/1067 , A61N5/1069 , A61N5/107 , A61N5/1082 , A61N2005/1051 , A61N2005/1052 , A61N2005/1054 , A61N2005/1061 , A61N2005/1074 , A61N2005/1087 , A61N2005/1095 , A61N2005/1097 , G21K1/08 , G21K1/087 , G21K1/093 , G21K5/04 , H01J35/14
摘要： The invention comprises a method and apparatus for proton treatment of a tumor, comprising the steps of a central control system: (1) receiving an initial cancer treatment irradiation plan; (2) directing a treatment of the tumor using the positively charged particles; (3) during a treatment session and after the step of directing the treatment of the tumor, receiving imaging input from an imaging system; (4) generating an updated cancer treatment irradiation plan using the imaging input; (5) continuing the treatment session using the updated cancer treatment irradiation plan; and (6) optionally, while the patient remains in the treatment room and under approval of a medical professional not in line of sight of the patient, repeating at least three times the steps of: receiving imaging input from the imaging system; generating an updated cancer treatment irradiation plan; and continuing the treatment session using the updated cancer treatment irradiation plan.

5. 发明授权

US09744380B2 Patient specific beam control assembly of a cancer therapy apparatus and method of use thereof 有权
公开(公告)号：US09744380B2
公开(公告)日：2017-08-29
申请号：US15207245
申请日：2016-07-11
申请人： Susan L. Michaud , Daniel J. Raymond , Stephen L. Spotts
发明人： Susan L. Michaud , Daniel J. Raymond , Stephen L. Spotts
IPC分类号： A61N5/00 , A61N5/10 , A61B6/03 , G21K5/04 , A61B6/00 , G21K1/08
CPC分类号： A61N5/1081 , A61B6/03 , A61B6/032 , A61B6/4216 , A61B6/4258 , A61B6/5205 , A61N5/1037 , A61N5/1039 , A61N5/1044 , A61N5/1067 , A61N5/1069 , A61N5/107 , A61N5/1077 , A61N5/1082 , A61N2005/1054 , A61N2005/1087 , A61N2005/1095 , A61N2005/1097 , G21K1/08 , G21K5/04
摘要： The invention comprises a patient specific tray insert removably inserted into a tray frame to form a beam control tray assembly, which is removably inserted into a slot of a tray receiver assembly proximate a gantry nozzle of a charged particle cancer treatment system. Optionally, multiple tray inserts, each used to control a different beam state parameter, are inserted into corresponding slots of the tray receiver assembly where the multiple inserts are used to control beam intensity, shape, focus, and/or energy. The beam control tray assembling includes an identifier, such as an electromechanical identifier, of the particular insert type, which is communicated to a main controller, such as via the tray receiver assembly along with slot position and/or patient information.

6. 发明申请

US20160271424A1 CHARGED PARTICLE STATE DETERMINATION APPARATUS AND METHOD OF USE THEREOF 审中-公开
标题翻译：充电颗粒状态测定装置及其使用方法
公开(公告)号：US20160271424A1
公开(公告)日：2016-09-22
申请号：US15167617
申请日：2016-05-27
申请人： W. Davis Lee , Stephen L. Spotts , Susan L. Michaud
发明人： W. Davis Lee , Stephen L. Spotts , Susan L. Michaud
IPC分类号： A61N5/10
CPC分类号： A61N5/1069 , A61B6/032 , A61B6/4258 , A61B6/5205 , A61N5/1037 , A61N5/1044 , A61N5/1067 , A61N5/107 , A61N5/1077 , A61N5/1082 , A61N2005/105 , A61N2005/1054 , A61N2005/1087 , A61N2005/1095 , A61N2005/1097 , G21K1/08 , G21K5/04
摘要： The invention comprises a system for determining the state of a charged particle beam, such as beam position, intensity, and/or energy. For example, the charged particle beam state is determined at or about a patient undergoing charged particle cancer therapy using one or more film layers designed to emit photons upon passage of a charged particle beam, which yields information on position and/or intensity of the charged particle beam. The emitted photons are used to calculate position of the treatment beam in imaging and/or during tumor treatment. Optionally and preferably, updating a tomography map uses the same hardware with the same alignment used for cancer therapy at proximately the same time.
摘要翻译：本发明包括用于确定带电粒子束的状态的系统，例如光束位置，强度和/或能量。例如，带电粒子束状态是在使用一个或多个设计成在带电粒子束通过时发射光子的一个或多个膜层进行带电粒子癌治疗的患者或周围确定的，其产生关于带电粒子束的位置和/或强度的信息粒子束。发射的光子用于计算成像和/或肿瘤治疗期间治疗束的位置。任选且优选地，更新断层摄影图使用与大致相同的时间使用与癌症治疗相同的比对的相同的硬件。

7. 发明申请

US20160250503A1 TREATMENT DELIVERY CONTROL SYSTEM AND METHOD OF OPERATION THEREOF 审中-公开
标题翻译：治疗传送控制系统及其操作方法
公开(公告)号：US20160250503A1
公开(公告)日：2016-09-01
申请号：US15152479
申请日：2016-05-11
申请人： Vladimir Balakin , Stephen L. Spotts
发明人： Vladimir Balakin , Stephen L. Spotts
IPC分类号： A61N5/10 , A61B6/03
CPC分类号： A61N5/1077 , A61B6/03 , A61N5/1044 , A61N5/1067 , A61N5/107 , A61N5/1082 , A61N2005/1074 , A61N2005/1087 , A61N2005/1097 , G21K1/087 , G21K1/093 , G21K5/04 , H01J35/14
摘要： The invention relates to a method and apparatus for control of a charged particle cancer therapy system. A treatment delivery control system is used to directly control multiple subsystems of the cancer therapy system without direct communication between selected subsystems, which enhances safety, simplifies quality assurance and quality control, and facilitates programming. For example, the treatment delivery control system directly controls one or more of: an imaging system, a positioning system, an injection system, a radio-frequency quadrupole system, a ring accelerator or synchrotron, an extraction system, a beam line, an irradiation nozzle, a gantry, a display system, a targeting system, and a verification system. Generally, the control system integrates subsystems and/or integrates output of one or more of the above described cancer therapy system elements with inputs of one or more of the above described cancer therapy system elements.
摘要翻译：本发明涉及一种用于控制带电粒子癌症治疗系统的方法和装置。治疗传递控制系统用于直接控制癌症治疗系统的多个子系统，而不选择子系统之间的直接通信，这增强了安全性，简化了质量保证和质量控制，并且有助于编程。例如，治疗传递控制系统直接控制成像系统，定位系统，注射系统，射频四极杆系统，环加速器或同步加速器，提取系统，束线，照射中的一个或多个喷嘴，龙门架，显示系统，瞄准系统和验证系统。通常，控制系统集成子系统和/或将上述癌症治疗系统元件中的一个或多个的输出与上述癌症治疗系统元件中的一个或多个的输入集成。

8. 发明授权

US10213626B2 Treatment delivery control system and method of operation thereof 有权
公开(公告)号：US10213626B2
公开(公告)日：2019-02-26
申请号：US15152479
申请日：2016-05-11
申请人： Vladimir Balakin , Stephen L. Spotts
发明人： Vladimir Balakin , Stephen L. Spotts
IPC分类号： A61N5/10 , A61B6/03 , G21K1/093 , G21K5/04 , G21K1/087 , H01J35/14
摘要： The invention relates to a method and apparatus for control of a charged particle cancer therapy system. A treatment delivery control system is used to directly control multiple subsystems of the cancer therapy system without direct communication between selected subsystems, which enhances safety, simplifies quality assurance and quality control, and facilitates programming. For example, the treatment delivery control system directly controls one or more of: an imaging system, a positioning system, an injection system, a radio-frequency quadrupole system, a ring accelerator or synchrotron, an extraction system, a beam line, an irradiation nozzle, a gantry, a display system, a targeting system, and a verification system. Generally, the control system integrates subsystems and/or integrates output of one or more of the above described cancer therapy system elements with inputs of one or more of the above described cancer therapy system elements.

9. 发明申请

US20180185673A1 MULTIPLE CATION CANCER THERAPY APPARATUS AND METHOD OF USE THEREOF 审中-公开
公开(公告)号：US20180185673A1
公开(公告)日：2018-07-05
申请号：US15907076
申请日：2018-02-27
申请人： W. Davis Lee , Mark R. Amato , Scott Penfold , Stephen L. Spotts
发明人： W. Davis Lee , Mark R. Amato , Scott Penfold , Stephen L. Spotts
IPC分类号： A61N5/10 , G21K1/087 , G21K5/04 , A61B6/03 , G21K1/093 , H01J35/14
CPC分类号： A61N5/1077 , A61B6/00 , A61B6/03 , A61B6/032 , A61B6/4258 , A61B6/5205 , A61N5/1037 , A61N5/1039 , A61N5/1044 , A61N5/1049 , A61N5/1067 , A61N5/1069 , A61N5/107 , A61N5/1082 , A61N2005/1051 , A61N2005/1052 , A61N2005/1054 , A61N2005/1061 , A61N2005/1074 , A61N2005/1087 , A61N2005/1095 , A61N2005/1097 , G21K1/08 , G21K1/087 , G21K1/093 , G21K5/04 , H01J35/14
摘要： The invention comprises a method and apparatus for imaging and/or treating a tumor of a patient using multiple ion types, such as a cations with one, two, or more mass-to-charge ratios and/or electrons, where the multiple ion types are accelerated, at separate times, using a single accelerator, and the multiple ion types are used to treat different depths into a tumor of a patient, where the patient is optionally maintained in a single treatment position relative to a patient positioning system during treatment.

10. 发明授权

US09974978B2 Scintillation array apparatus and method of use thereof 有权
公开(公告)号：US09974978B2
公开(公告)日：2018-05-22
申请号：US15239773
申请日：2016-08-17
申请人： W. Davis Lee , Mark R. Amato , Stephen L. Spotts , James P. Bennett
发明人： W. Davis Lee , Mark R. Amato , Stephen L. Spotts , James P. Bennett
IPC分类号： A61N5/00 , A61N5/10 , A61B6/03 , G21K1/093 , G21K5/04 , A61B6/00 , G01N23/04 , A61B6/04
CPC分类号： A61N5/1069 , A61B6/03 , A61B6/032 , A61B6/0457 , A61B6/4014 , A61B6/4092 , A61B6/4258 , A61B6/4266 , A61B6/4417 , A61B6/4435 , A61B6/5205 , A61B6/5247 , A61N5/1037 , A61N5/1039 , A61N5/1067 , A61N5/107 , A61N5/1077 , A61N5/1082 , A61N2005/105 , A61N2005/1054 , A61N2005/1061 , A61N2005/1087 , A61N2005/1095 , A61N2005/1097 , G01N23/046 , G01N2223/107 , G01N2223/203 , G21K1/093 , G21K5/04
摘要： A scintillation material is longitudinally packaged in a circumferentially surrounding sheath, where the sheath has a lower index of refraction than the scintillation material, to form a scintillation optic or scintillation fiber optic. The scintillation material yields secondary photons upon passage of a charged particle beam, such as a positively charged residual particle beam having transmitted through a sample. The internally generated secondary photons within the sheath are guided to a detector element by the difference in index of refraction. Multiple scintillation optics are assembled to form a two-dimensional scintillation array coupled to a two-dimensional detector array, such as for use in determination of state of the residual charged particle beam, determination of an exit point of the particle beam from the sample, path of the treatment beam, and/or tomographic imaging.

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