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1. 发明授权

US09918831B2 Aspheric optical lenses and associated systems and methods 有权
公开(公告)号：US09918831B2
公开(公告)日：2018-03-20
申请号：US13316692
申请日：2011-12-12
申请人： Robert Angelopoulos , Stephen J. Van Noy
发明人： Robert Angelopoulos , Stephen J. Van Noy
IPC分类号： A61F2/16 , B29D11/02 , G02C7/04
CPC分类号： A61F2/1616 , A61F2/164 , B29D11/023 , G02C7/042
摘要： Aspheric optical lenses (e.g., intraocular lenses and contact lenses) are provided. The intraocular lens includes a body portion defining an anterior optical surface and an opposing posterior optical surface. The anterior optical surface includes a central region surrounded by a first outer region and a second outer region. The central region has a first asphericity profile. The first outer region has a second asphericity profile that is different than the first asphericity profile of the central region. The second outer region has a third asphericity profile that is different than the second asphericity profile of the first outer region. The overall asphericity profile of the optical lens provides different depths of focus for different pupil sizes. The result is an optical lens that provides increased depth of focus or pseudo-accommodation while maintaining desired optical power and performance.

2. 发明授权

US09421092B2 Automated intraocular lens injector device 有权
标题翻译：自动人工晶状体注射装置
公开(公告)号：US09421092B2
公开(公告)日：2016-08-23
申请号：US12702465
申请日：2010-02-09
申请人： Kyle Brown , David A. Downer , Sushant Muchhala , Stephen J. Van Noy , Dengzhua (Dan) Yan , Marshall K. Proulx
发明人： Kyle Brown , David A. Downer , Sushant Muchhala , Stephen J. Van Noy , Dengzhua (Dan) Yan , Marshall K. Proulx
IPC分类号： A61F2/16
CPC分类号： A61F2/1678
摘要： An intraocular lens injector cartridge assembly contains a pre-loaded lens and an integral lens-contacting plunger rod. Configured for removably mating with an injector handpiece, the cartridge assembly is suitable for use with either manual or automated injector systems. The injector cartridge assembly includes a tubular body having a longitudinal bore extending between a distal end and a proximal end, an IOL disposed within said longitudinal bore, and a lens-contacting plunger rod retained within said bore, between the IOL and the proximal end of the tubular body. The lens-contacting plunger rod is configured for translation along the longitudinal bore upon engagement by an injector rod introduced by the injector handpiece into the proximal end of the tubular body, so that the IOL is folded and ejected from the distal end of the tubular body by the translation of the lens-contacting plunger rod.
摘要翻译：眼内透镜注射器盒组件包含预加载的透镜和整体的透镜接触柱塞杆。配置为可拆卸地与注射器手柄配合，盒组件适用于手动或自动注射器系统。注射器套筒组件包括管状体，其具有在远端和近端之间延伸的纵向孔，设置在所述纵向孔内的IOL和保持在所述孔内的透镜接触柱塞杆，位于IOL和近端之间管状体。透镜接触柱塞杆构造成在通过由注射器手柄引入的注射器杆接合到管状体的近端中时沿着纵向孔平移，使得IOL从管状体的远端折叠并弹出通过镜片接触柱塞杆的平移。

3. 发明申请

US20110060408A1 INTRAOCULAR LENSES WITH INTERLENTICULAR OPACIFICATION RESISTANCE 有权
标题翻译：具有相互抵触能力的内窥镜
公开(公告)号：US20110060408A1
公开(公告)日：2011-03-10
申请号：US12874863
申请日：2010-09-02
申请人： Chi-Chun Tsai , Brett E. Thomes , Stephen J. Van Noy
发明人： Chi-Chun Tsai , Brett E. Thomes , Stephen J. Van Noy
IPC分类号： A61F2/16
CPC分类号： A61F2/16 , A61F2/1613 , A61F2/1648 , A61F2002/009 , A61F2002/1681 , A61F2250/0056
摘要： The present invention is directed to an intraocular lens, an intraocular lens system and a method of producing and/or implanting the lens or system in an eye wherein at least one intraocular lens includes a coating that aids in resisting interlenticular opacification (ILO). The material of the coating is preferably hydrophilic or super-hydrophobic.
摘要翻译：本发明涉及眼内透镜，眼内透镜系统以及在眼睛中制造和/或植入晶状体或系统的方法，其中至少一个眼内透镜包括有助于抵抗间质不透明化的涂层（ILO）。涂层的材料优选是亲水的或超疏水的。

4. 发明申请

US20110022170A1 Truncated diffractive intraocular lenses 审中-公开
$Truncated diffractive intraocular lenses$
标题翻译：截断的衍射眼内透镜
公开(公告)号：US20110022170A1
公开(公告)日：2011-01-27
申请号：US12847214
申请日：2010-07-30
申请人： Michael J. Simpson , Mutlu Karakelle , Stephen J. Van Noy , Xiaoxiao Zhang , Xin Hong , Jihong Xie
发明人： Michael J. Simpson , Mutlu Karakelle , Stephen J. Van Noy , Xiaoxiao Zhang , Xin Hong , Jihong Xie
IPC分类号： A61F2/16 , G02C7/02 , G02C7/06
CPC分类号： A61F2/1654 , A61F2/1618 , G02C7/042 , G02C7/044 , G02C2202/20
摘要： In one aspect, the present invention provides a method of designing a diffractive ophthalmic lens (e.g., an intraocular lens (IOL)) that includes providing an optic having an anterior refractive surface and a posterior refractive surface, wherein the optic provides a far-focus power (e.g., in a range of about 18 to about 26 Diopters (D)). A truncated diffractive structure can be disposed on at least one of the surfaces for generating a near-focus add power (e.g., in a range of about 3 D to about 4 D). And the diffractive structure can be adjusted so as to obtain a desired distribution of optical energy between the near and far foci for a range of pupil sizes.
摘要翻译：一方面，本发明提供了一种设计衍射眼用透镜（例如，眼内透镜（IOL））的方法，其包括提供具有前折射表面和后折射表面的光学元件，其中所述光学元件提供远焦点功率（例如，在约18至约26屈光度（D）的范围内）。截面的衍射结构可以设置在至少一个表面上，用于产生近焦点添加功率（例如，在约3D至约4D的范围内）。并且可以调整衍射结构，以便在一定范围的瞳孔尺寸之间获得近焦点和远焦点之间期望的光能分布。

5. 发明申请

US20100204705A1 Automated Intraocular Lens Injector Device 有权
标题翻译：自动人工晶状体注射器装置
公开(公告)号：US20100204705A1
公开(公告)日：2010-08-12
申请号：US12702465
申请日：2010-02-09
申请人： Kyle Brown , David A. Downer , Sushant Muchhala , Stephen J. Van Noy , Dengzhua (Dan) Yan , Marshall K. Proulx
发明人： Kyle Brown , David A. Downer , Sushant Muchhala , Stephen J. Van Noy , Dengzhua (Dan) Yan , Marshall K. Proulx
IPC分类号： A61F9/007
CPC分类号： A61F2/1678
摘要： An intraocular lens injector cartridge assembly contains a pre-loaded lens and an integral lens-contacting plunger rod. Configured for removably mating with an injector handpiece, the cartridge assembly is suitable for use with either manual or automated injector systems. The injector cartridge assembly includes a tubular body having a longitudinal bore extending between a distal end and a proximal end, an IOL disposed within said longitudinal bore, and a lens-contacting plunger rod retained within said bore, between the IOL and the proximal end of the tubular body. The lens-contacting plunger rod is configured for translation along the longitudinal bore upon engagement by an injector rod introduced by the injector handpiece into the proximal end of the tubular body, so that the IOL is folded and ejected from the distal end of the tubular body by the translation of the lens-contacting plunger rod.
摘要翻译：眼内透镜注射器盒组件包含预加载的透镜和整体的透镜接触柱塞杆。配置为可拆卸地与注射器手柄配合，盒组件适用于手动或自动注射器系统。注射器套筒组件包括管状体，其具有在远端和近端之间延伸的纵向孔，设置在所述纵向孔内的IOL和保持在所述孔内的透镜接触柱塞杆，位于IOL和近端之间管状体。透镜接触柱塞杆构造成在通过由注射器手柄引入的注射器杆接合到管状体的近端中时沿着纵向孔平移，使得IOL从管状体的远端折叠并弹出通过镜片接触柱塞杆的平移。

6. 发明授权

US06187042B1 Intraocular lens coating compositions 失效
标题翻译：人工晶状体涂层组合物
公开(公告)号：US06187042B1
公开(公告)日：2001-02-13
申请号：US09283701
申请日：1999-04-01
申请人： John W. Sheets, Jr. , Albert R. Leboeuf , Anilbhai S. Patel , Mutlu Karakelle , Stephen J. Van Noy
发明人： John W. Sheets, Jr. , Albert R. Leboeuf , Anilbhai S. Patel , Mutlu Karakelle , Stephen J. Van Noy
IPC分类号： A61F216
CPC分类号： A61L27/16 , Y10S623/926 , C08L33/04
摘要： Intraocular lens coating compositions for reducing the risk of posterior capsule opacification are disclosed. The coating materials, which differ from the substrate material, consist essentially of at least two aryl acrylic hydrophobic monomers of the formula wherein: X is H or CH3; m is 0-10; Y is nothing, O, S, or NR wherein R is H, CH3, CnH2n+1 (n=1−10) iso OC3H7, C6H5, or CH2C6H5; Ar is any aromatic ring which can be unsubstituted or substituted with CH3, C2H5, n-C3H7, iso-C3H7, OCH3, C6H11, Cl, Br, C6H5, or CH2C6H5.
摘要翻译：公开了用于降低后囊混浊风险的眼内透镜涂层组合物。与衬底材料不同的涂层材料基本上由至少两种芳族化合物的芳基丙烯酸疏水性单体组成：X是H或CH 3; m是0-10; Y不是O，S或NR，其中R是 H，CH 3，C n H 2n + 1（n = 1-10）异OC 3 H 7，C 6 H 5或CH 2 C 6 H 5; Ar是可以被未取代或被CH 3，C 2 H 5，n-C 3 H 7，异-C 3 H 7，OCH 3，C 6 H 11， Cl，Br，C6H5或CH2C6H5。

7. 发明授权

US5947976A Asymmetric intraocular lens injection cartridge 失效
公开(公告)号：US5947976A
公开(公告)日：1999-09-07
申请号：US089284
申请日：1998-06-02
申请人： Stephen J. Van Noy , Kyle Brown , David A. Downer , David Eister , Lars D. Jensen
发明人： Stephen J. Van Noy , Kyle Brown , David A. Downer , David Eister , Lars D. Jensen
IPC分类号： A61F9/007 , A61F2/16 , A61F9/00
CPC分类号： A61F9/00 , A61F2/1664
摘要： A lens injector cartridge having an asymmetric bore. The asymmetric bore initiates the folding of the lens on one side only, thereby reducing the amount of energy imparted to the lens and the potential for damage to the lens. The gentle folding of the lens also assists in positioning the travel of the haptics down the bore, thereby reducing the potential for damage to the haptics.

8. 发明授权

US09233069B2 Ophthalmic device having therapeutic agent delivery capability and method of forming same 有权
标题翻译：具有治疗剂递送能力的眼科装置及其形成方法
公开(公告)号：US09233069B2
公开(公告)日：2016-01-12
申请号：US12505558
申请日：2009-07-20
申请人： Brett E. Thomas , Stephen J. Van Noy , Chi-Chun Tsai
发明人： Brett E. Thomas , Stephen J. Van Noy , Chi-Chun Tsai
IPC分类号： A61K31/165 , A61K9/00
CPC分类号： A61K9/0051 , A61K31/165 , A61K31/4985 , A61K47/32
摘要： The present invention is directed to ophthalmic devices that are loaded with therapeutic agent. The devices provide prolonged release of the therapeutic agent to the eye. The ophthalmic devices are typically formed of an ophthalmic material that is particularly desirable for the loading of therapeutic agent and/or the therapeutic agent is typically particularly desirable for loading to the ophthalmic material.
摘要翻译：本发明涉及装载有治疗剂的眼科装置。这些装置使治疗剂延长释放到眼睛。眼科装置通常由眼药物形成，其特别适用于治疗剂的加载和/或治疗剂通常特别需要用于装载到眼科材料中。

9. 发明授权

US08317860B2 Stable anterior chamber phakic lenses 有权
标题翻译：稳定的前房晶状体
公开(公告)号：US08317860B2
公开(公告)日：2012-11-27
申请号：US12419680
申请日：2009-04-07
申请人： Raymie H. Lindsey , James M. Scott , Stephen J. Van Noy
发明人： Raymie H. Lindsey , James M. Scott , Stephen J. Van Noy
IPC分类号： A61F2/16
CPC分类号： A61F2/1616 , A61F2/1605
摘要： An anterior chamber phakic lens made from a foldable, highly biocompatible material that has a very low haptic compression force and low axial displacement, yet is stable in the anterior chamber.
摘要翻译：由可折叠，高度生物相容的材料制成的前房晶状体透镜，其具有非常低的触觉压缩力和低轴向位移，但在前房中是稳定的。

10. 发明授权

US06537283B2 Intraocular lens shipping case and injection cartridge 有权
标题翻译：人工晶状体运输箱和注射筒
公开(公告)号：US06537283B2
公开(公告)日：2003-03-25
申请号：US09932285
申请日：2001-08-17
申请人： Stephen J. Van Noy
发明人： Stephen J. Van Noy
IPC分类号： A61F900
CPC分类号： A61F2/1678 , A61F2/1691
摘要： An intraocular lens cartridge having a distal injector portion and a proximal shipping portion. The injector portion and the shipping portion are join be a hinge that allows the shipping portion to be rotated so that the lens, when held in the shipping portion, aligns with the bore of the injector portion. The shipping portion may also be flexible so as to provide a prefold to the lens.
摘要翻译：一种眼内透镜盒，其具有远端注射器部分和近端运送部分。喷射器部分和运送部分被连接成允许运输部分旋转的铰链，使得当保持在运输部分中的透镜与喷射器部分的孔对准时。运送部分也可以是柔性的，以便为镜片提供折叠。

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