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    • 1. 发明授权
    • Process and compositions for synthetic calibration of bio-photonic scanners
    • 生物光子扫描仪的合成校准工艺和组成
    • US07365839B2
    • 2008-04-29
    • US10981139
    • 2004-11-03
    • Scott FergusonStephen J. Poole
    • Scott FergusonStephen J. Poole
    • G01J1/10G01J3/44
    • G01N21/274G01N21/65
    • A method, apparatus, and set of compositions are disclosed for calibrating a bio-photonic scanner. The scanner detects selected molecular structures of tissues, nondestructively, in vivo. The apparatus may include a computer, including processor and memory connecting to the scanner, including an illuminator to direct light nondestructively onto tissue in vivo, a detector to detect an intensity of a radiant response of the tissue to the light, and a probe to direct light onto the subject and receive a radiant response back into the detector. The apparatus is calibrated using a synthetic material to mimic the radiant response of live tissue, correcting for background fluorescence and elastic scattering. Dopants in a matrix of synthetic material mimic selected molecular structures of tissue. Matrix materials include a dilatant compound, and dopants include biological materials as well as K-type polarizing film powdered and mixed.
    • 公开了用于校准生物光子扫描仪的方法,装置和组合。 扫描仪在体内非破坏性地检测组织的选定分子结构。 该装置可以包括计算机,包括连接到扫描器的处理器和存储器,包括用于将光非破坏性地将光引导到体内的照明器,用于检测组织对光的辐射响应的强度的检测器,以及用于引导 将光照射到被摄体上并接收到辐射响应回到检测器中。 使用合成材料校准装置以模拟活组织的辐射响应,校正背景荧光和弹性散射。 合成材料基质中的掺杂剂模拟组织的选定分子结构。 基质材料包括膨胀化合物,掺杂剂包括生物材料以及K型偏光膜粉末和混合物。