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1. 发明申请

US20090143736A1 CATHETER STYLET WITH CATHETER ACCOMMODATING LUMEN 有权
标题翻译：导管架与导管容纳灯
公开(公告)号：US20090143736A1
公开(公告)日：2009-06-04
申请号：US12326981
申请日：2008-12-03
申请人： Stephan Mittermeyer , Christoph Pedain
发明人： Stephan Mittermeyer , Christoph Pedain
IPC分类号： A61M25/00
CPC分类号： A61M25/0102 , A61M25/0045 , A61M25/0054 , A61M2025/0004 , A61M2025/0063
摘要： The invention relates to a catheter stylet for stiffening a catheter during the placing process, wherein the stylet comprises an accommodating lumen for at least one fluid-guiding line of the catheter. It also relates to a catheter stylet catheter system, comprising such a stylet and comprising a catheter which comprises a fluid-guiding line, and to a method for stiffening a catheter during the placing process, wherein a stylet which comprises an accommodating lumen is arranged around at least one fluid-guiding line of the catheter.
摘要翻译：本发明涉及用于在放置过程中加强导管的导管探针，其中探针包括用于导管的至少一个流体引导线的容纳腔。它还涉及一种导管探针导管系统，其包括这种探针并且包括导管，其包括流体引导线，以及用于在放置过程期间加强导管的方法，其中包括容纳腔的探针设置在导管的至少一个流体引导线。

2. 发明申请

WO2012116747A1 COMPUTER-ASSISTED INFUSION PLANNING AND SIMULATION 审中-公开
标题翻译：计算机辅助灌输计划和模拟
公开(公告)号：WO2012116747A1
公开(公告)日：2012-09-07
申请号：PCT/EP2011/053156
申请日：2011-03-03
申请人： BRAINLAB AG , STEPHAN, Mittermeyer
发明人： STEPHAN, Mittermeyer
IPC分类号： G06F19/00 , A61B19/00 , A61M5/142 , A61M5/14
CPC分类号： G16H50/50 , A61B34/10 , A61B2034/101 , A61M2005/1406 , A61M2005/14208 , A61M2005/14292 , G06F19/00 , G06F19/3468
摘要： A method for planning an infusion of a medical liquid by an infusion apparatus comprising an infusion device, wherein the method comprises the steps of: acquiring planning scan data which represent a medical image of at least a body region (3) of a patient and are obtained by a planning scan before the infusion device is positioned; determining a planned device position from the planning scan data; acquiring verification scan data which represent a medical image of the region of the patient after the infusion device has been positioned; determining a source volume of the liquid from the verification scan data; and determining infusion parameters from the verification scan data and the source volume.
摘要翻译：一种用于通过包括输注装置的输注装置计划输液医疗液体的方法，其中所述方法包括以下步骤：获取代表患者的至少身体区域（3）的医学图像的规划扫描数据，并且是在输液装置定位之前通过计划扫描获得; 从所述规划扫描数据确定计划的设备位置; 获取验证扫描数据，所述验证扫描数据代表在所述输注装置定位之后的所述患者区域的医学图像; 从所述验证扫描数据确定所述液体的源体积; 以及从验证扫描数据和源体积确定输注参数。

3. 发明授权

US09449149B2 Method for optimising local drug delivery 有权
标题翻译：优化局部药物递送的方法
公开(公告)号：US09449149B2
公开(公告)日：2016-09-20
申请号：US14113308
申请日：2011-05-11
申请人： Rowena Thomson , Stephan Mittermeyer
发明人： Rowena Thomson , Stephan Mittermeyer
IPC分类号： G06K9/00 , G06F19/00 , A61B5/05
CPC分类号： G06F19/3468 , G06F19/00 , G16H50/20
摘要： The present invention relates to a data processing method for determining an infusion location in an anatomical region of interest of a patient's body for infusing a medical substance, the method being executed by a computer and comprising steps of: a) acquiring permeability data comprising information about the permeability of anatomical vessels in the body; b) acquiring body vessels set data comprising information about a body vessel set, wherein the body vessel set represents a set of at least one anatomical body vessel in the patient's body and wherein the body vessel set data comprises information about the spatial structure of the at least one body vessel; c) acquiring coverage condition data comprising information about a predetermined coverage of a target region with the medical substance; d) determining, for a plurality of candidate infusion locations, candidate coverage data comprising information about a candidate coverage of a target region with the medical substance based on the permeability data, the body vessel set data and the coverage condition data; e) determining infusion location data comprising information about the infusion location based on the permeability data, the body vessel set data and the coverage condition data.
摘要翻译：本发明涉及一种数据处理方法，用于确定患者身体感兴趣的解剖学区域中用于注射医疗物质的输注位置，该方法由计算机执行，该方法包括以下步骤：a）获取包含关于解剖血管在体内的渗透性; b）获取身体容器设置包括关于身体血管集合的信息的数据，其中所述体容器组表示患者身体中的一组至少一个解剖体体血管，并且其中所述身体血管设置数据包括关于所述患者的空间结构的信息至少一个身体血管; c）获取覆盖条件数据，所述覆盖条件数据包括关于所述医疗物质的目标区域的预定覆盖范围的信息; d）针对多个候选输注位置，基于所述渗透率数据，所述身体血管集合数据和所述覆盖条件数据，确定包括关于所述医疗物质的目标区域的候选覆盖度的信息的候选覆盖数据; e）基于渗透性数据，身体血管集数据和覆盖条件数据确定包括关于输注位置的信息的输注位置数据。

4. 发明申请

US20130035921A1 METHOD AND APPARATUS FOR ESTIMATING TEMPERATURE IN A BODY 审中-公开
标题翻译：用于估算身体温度的方法和装置
公开(公告)号：US20130035921A1
公开(公告)日：2013-02-07
申请号：US13575637
申请日：2010-01-28
申请人： Maria Inmaculada Rodriguez-Ponce , Stephan Mittermeyer
发明人： Maria Inmaculada Rodriguez-Ponce , Stephan Mittermeyer
IPC分类号： G06G7/56
CPC分类号： A61B5/417 , A61B5/015 , A61B5/055 , A61N1/403 , G01R33/4804 , G01R33/56366 , G09B23/28
摘要： The invention relates a method and an apparatus of predicting or planning a temperature distribution (52) in a body. The method comprises the steps of : a) obtaining a model of the body (50) related to a temperature transport mechanism or temperature distribution (52) in the body; b) simulating an application of heat to at least a part of the body such as targeted tissue; c) determining and/or predicting the temperature (52) or heat distribution in at least a part of the body using the model of the body (50).
摘要翻译：本发明涉及一种预测或规划身体温度分布（52）的方法和装置。该方法包括以下步骤：a）获得与身体温度传递机构或温度分布（52）相关的身体（50）的模型; b）模拟对身体的至少一部分（例如靶组织）施加热量; c）使用身体（50）的模型来确定和/或预测身体的至少一部分中的温度（52）或热分布。

5. 发明授权

US08251955B2 Catheter stylet with catheter accommodating lumen 有权
标题翻译：导管管心针导管容纳内腔
公开(公告)号：US08251955B2
公开(公告)日：2012-08-28
申请号：US12326981
申请日：2008-12-03
申请人： Stephan Mittermeyer , Christoph Pedain
发明人： Stephan Mittermeyer , Christoph Pedain
IPC分类号： A61M5/178 , A61F11/00
CPC分类号： A61M25/0102 , A61M25/0045 , A61M25/0054 , A61M2025/0004 , A61M2025/0063
摘要： The invention relates to a catheter stylet for stiffening a catheter during the placing process, wherein the stylet comprises an accommodating lumen for at least one fluid-guiding line of the catheter. It also relates to a catheter stylet catheter system, comprising such a stylet and comprising a catheter which comprises a fluid-guiding line, and to a method for stiffening a catheter during the placing process, wherein a stylet which comprises an accommodating lumen is arranged around at least one fluid-guiding line of the catheter.
摘要翻译：本发明涉及一种用于在放置过程中加强导管的导管探针，其中探针包括用于导管的至少一个流体引导线的容纳腔。它还涉及一种导管探针导管系统，其包括这种探针并且包括导管，其包括流体引导线，以及用于在放置过程期间加强导管的方法，其中包括容纳腔的探针设置在导管的至少一个流体引导线。

6. 发明申请

US20080228168A1 CATHETER WITH CHANGING MATERIAL PROPERTIES 审中-公开
标题翻译：具有改变材料特性的导管
公开(公告)号：US20080228168A1
公开(公告)日：2008-09-18
申请号：US12048919
申请日：2008-03-14
申请人： Stephan Mittermeyer , Andreas Hartlep
发明人： Stephan Mittermeyer , Andreas Hartlep
IPC分类号： A61M25/01
CPC分类号： A61L29/14 , A61L29/145 , A61M25/0045 , A61M25/0054 , A61M2025/0048
摘要： A catheter for administering a substance into a patient's tissue includes an elongated catheter body surrounding a lumen. At least one part of the length of the catheter body includes a material that changes its stiffness due to changes in the ambient conditions in the administering environment.
摘要翻译：用于将物质施用到患者组织中的导管包括围绕内腔的细长导管体。导管主体的长度的至少一部分包括由于施用环境中的环境条件的变化而改变其刚度的材料。

7. 发明授权

US09449383B2 Determination of a physically-varying anatomical structure 有权
标题翻译：确定物理变化的解剖结构
公开(公告)号：US09449383B2
公开(公告)日：2016-09-20
申请号：US14115997
申请日：2011-05-17
申请人： Rowena Thomson , Stephan Mittermeyer , Rainer Lachner
发明人： Rowena Thomson , Stephan Mittermeyer , Rainer Lachner
IPC分类号： A61B5/05 , G06T7/00 , G06T7/20 , A61B5/06 , G06T5/50
CPC分类号： G06T7/0012 , A61B5/061 , G06T5/50 , G06T7/0016 , G06T7/215 , G06T7/97 , G06T2207/30016 , G06T2207/30096
摘要： The present invention relates to a data processing method for providing variation data which describe a physically-varying anatomical structure, in particular an indiscernible anatomical structure, in particular a non-enhancing tumor, comprising the steps of: providing second image data which describe a second image of a region of an anatomical body, wherein the region includes a second anatomical part which includes the physically-varying anatomical structure; providing first image data which represent a first image of the same region, wherein said same region includes a first anatomical part which does not include the physically-varying anatomical structure or which includes the physically-varying anatomical structure in a different physical state than in the second anatomical part; providing position change data which describe positional changes of corresponding image elements between the first image and the second image, on the basis of the first and second image data; and providing the variation data on the basis of the position change data.
摘要翻译：本发明涉及一种数据处理方法，用于提供描述物理变化的解剖结构，特别是不可辨认的解剖结构，特别是非增强肿瘤的变化数据，包括以下步骤：提供描述第二图像数据的第二图像数据解剖体的区域的图像，其中所述区域包括包括物理变化的解剖结构的第二解剖部分; 提供表示相同区域的第一图像的第一图像数据，其中所述相同区域包括不包括物理变化的解剖结构的第一解剖部分，或者包括物理上不同的物理状态的解剖结构，而不同于第二解剖部位; 提供基于第一和第二图像数据描述第一图像和第二图像之间的对应图像元素的位置变化的位置变化数据; 以及基于位置变化数据提供变化数据。

8. 发明申请

US20130325432A1 METHOD FOR ENABLING THE PLANNING OF A TREATMENT OF A TUMOUR USING A THERAPEUTIC VIRUS 审中-公开
标题翻译：使用治疗病毒治疗肿瘤计划的方法
公开(公告)号：US20130325432A1
公开(公告)日：2013-12-05
申请号：US14001045
申请日：2011-03-18
申请人： Stephan Mittermeyer , Eva Wembacher-Schroder
发明人： Stephan Mittermeyer , Eva Wembacher-Schroder
IPC分类号： G06F19/00
CPC分类号： G16H50/50
摘要： A method for enabling the planning of a treatment of a tumour within a body using a therapeutic virus, wherein the virus distribution in the body is calculated by simulating the virus replication process, starting from an initial virus distribution, and the calculated virus distribution is provided for the planning.
摘要翻译：一种能够使用治疗性病毒来规划体内肿瘤治疗的方法，其中通过从初始病毒分布开始模拟病毒复制过程来计算身体中的病毒分布，并且提供计算出的病毒分布为规划。

9. 发明授权

US07883492B2 Catheter with portions that can change in volume 有权
标题翻译：导管与部分可以改变体积
公开(公告)号：US07883492B2
公开(公告)日：2011-02-08
申请号：US12049534
申请日：2008-03-17
申请人： Stephan Mittermeyer , Andreas Hartlep
发明人： Stephan Mittermeyer , Andreas Hartlep
IPC分类号： A61M29/00
CPC分类号： A61M25/0023 , A61M25/0045 , A61M2005/14292 , A61M2025/0057 , A61M2025/006 , A61M2025/1052
摘要： A catheter for administering a substance into body tissues includes an elongated catheter body that has at least one portion of the length of the catheter body that expands after the catheter is inserted in the patient's body. The portion that expands provides a seal against backflow of the substance along the outer surface of the catheter body and away from the intended treatment area.
摘要翻译：用于将物质施用到身体组织中的导管包括细长的导管体，其具有导管主体的长度的至少一部分，其在将导管插入患者体内后扩张。膨胀的部分提供密封，以防止物质沿着导管主体的外表面并远离预期治疗区域的回流。

10. 发明申请

US20090124976A1 DRUG SUPPLY SYSTEM FOR CED (CONVECTION-ENHANCED DELIVERY) CATHETER INFUSIONS 有权
标题翻译：用于CED（对照增强输送）导管输液的药物供应系统
公开(公告)号：US20090124976A1
公开(公告)日：2009-05-14
申请号：US12270877
申请日：2008-11-14
申请人： Stephan Mittermeyer
发明人： Stephan Mittermeyer
IPC分类号： A61M5/142
CPC分类号： A61M5/14526 , A61M31/00 , A61M2210/0693
摘要： The invention relates to a drug supply system for CED (convection-enhanced delivery) catheter infusions, comprising: a drug conducting system which comprises a drug depot and a catheter supply line; and a conveying device which provides for conveying the drug from the drug depot into the catheter supply line; wherein the drug conducting system is a system which is closed to the outside in a fluidic seal, and wherein a conveying fluid conveying system is arranged between the conveying device and the drug supply system and is connected on the one hand to the conveying device and on the other to the drug depot, via a drug displacement element, without fluid-drug contact.
摘要翻译：本发明涉及一种用于CED（对流增强递送）导管输注的药物供应系统，包括：药物传导系统，其包括药物贮库和导管供应管线; 以及输送装置，其用于将药物从药剂库输送到导管供给管线中; 其中所述药物传导系统是在流体密封中封闭到外部的系统，并且其中输送流体输送系统布置在输送装置和药物供应系统之间，并且一方面连接到输送装置上另一个到毒品库，通过药物置换元件，没有流体药物接触。

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