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    • 2. 发明申请
    • BLOOD ULTRAFILTRATION SUBSTITUTION TARGET METHOD AND DEVICE
    • 血液超滤替代目标方法和装置
    • US20130303961A1
    • 2013-11-14
    • US13885603
    • 2011-11-15
    • Henrik WolffStefan Moll
    • Henrik WolffStefan Moll
    • A61M1/14
    • A61M1/14A61M1/16A61M1/1617A61M1/3403A61M1/342A61M1/3441A61M1/3609A61M2205/3331A61M2205/52A61M2230/207
    • The present invention relates to a method as well as a blood treatment unit for the implementation of this method for the best possible attainment of a predetermined substitution target during the ultrafiltration of blood. According to the invention, a method and a blood treatment unit for the implementation of the method is provided, wherein it is determined by detection of pressure measurement values in the blood treatment unit whether the calculated substitution target is achieved at the end of the dialysis session or not and in case of the result that the calculated substitution target cannot be achieved with the current dialysis parameters, an adjustment of the flow rate of blood, dialysate and/or substituate is performed in order to achieve the substitution target for a given treatment time in an optimal way or modify the treatment time for the given substitution target as little as possible.
    • 本发明涉及一种方法以及用于实施该方法的血液处理单元,用于在超滤血液期间最佳地达到预定的替代目标。 根据本发明,提供了一种用于实施该方法的方法和血液处理单元,其中通过检测血液处理单元中的压力测量值来确定在透析会话结束时是否实现计算的替代目标 或者不是,并且在使用当前透析参数不能实现计算的替代目标的情况下,执行血液,透析液和/或取代物的流量的调整,以便在给定的治疗时间内实现替代靶标 以最佳方式或尽可能少地修改给定替代目标的治疗时间。
    • 5. 发明授权
    • Blood ultrafiltration substitution target method and device
    • 血液超滤取代靶标法及装置
    • US09364597B2
    • 2016-06-14
    • US13885603
    • 2011-11-15
    • Henrik WolffStefan Moll
    • Henrik WolffStefan Moll
    • A61M1/14A61M1/16A61M1/34
    • A61M1/14A61M1/16A61M1/1617A61M1/3403A61M1/342A61M1/3441A61M1/3609A61M2205/3331A61M2205/52A61M2230/207
    • The present invention relates to a method as well as a blood treatment unit for the implementation of this method for the best possible attainment of a predetermined substitution target during the ultrafiltration of blood. According to the invention, a method and a blood treatment unit for the implementation of the method is provided, wherein it is determined by detection of pressure measurement values in the blood treatment unit whether the calculated substitution target is achieved at the end of the dialysis session or not and in case of the result that the calculated substitution target cannot be achieved with the current dialysis parameters, an adjustment of the flow rate of blood, dialysate and/or substituate is performed in order to achieve the substitution target for a given treatment time in an optimal way or modify the treatment time for the given substitution target as little as possible.
    • 本发明涉及一种方法以及用于实施该方法的血液处理单元,用于在超滤血液期间最佳地达到预定的替代目标。 根据本发明,提供了一种用于实施该方法的方法和血液处理单元,其中通过检测血液处理单元中的压力测量值来确定在透析会话结束时是否实现计算的替代目标 或者不是,并且在使用当前透析参数不能实现计算的替代目标的情况下,执行血液,透析液和/或取代物的流量的调整,以便在给定的治疗时间内实现替代靶标 以最佳方式或尽可能少地修改给定替代目标的治疗时间。
    • 7. 发明申请
    • DEVICE FOR EXTRACORPOREAL BLOOD TREATMENT
    • 用于提取血液治疗的装置
    • US20120217189A1
    • 2012-08-30
    • US13394021
    • 2010-09-06
    • Jörn AhrensStefan MollAlex Castellarnau
    • Jörn AhrensStefan MollAlex Castellarnau
    • A61M1/16
    • A61M1/16A61M1/1607A61M1/1609A61M2205/3313A61M2205/3334A61M2205/50A61M2205/52
    • The invention is related to an apparatus for extracorporeal treatment of blood with a dialyzer which is separated by a semipermeable membrane into a first and a second chamber, wherein the first chamber is disposed in a dialysis fluid pathway and the second chamber is connectable to the blood circulation of a patient by means of a blood inflow conduit and a blood outflow conduit, a feed for fresh dialysis fluid, a discharge for spent dialysis fluid, a means for estimation of a flow QBlood in the blood inflow conduit respectively the blood outflow conduit, a means for determining a flow QDialysate in the dialysis fluid pathway, and a measuring device disposed in the discharge for estimation of the absorption ADialysate of the spent dialysis fluid flowing through the discharge, wherein the measuring device has at least one radiation source and a detector system for detection of the intensity of the electromagnetic radiation. Therein provided are a memory, wherein a formula A Blood = ( A Dialysate · Q Dialysate Q Blood ) is stored for the absorption ABlood, and an arithmetic unit for estimation of the absorption ABlood in the blood inflow conduit respectively the blood outflow conduit using the absorption ADialysate, the flow QDialysate, and the flow QBlood.
    • 本发明涉及一种用透析器体外处理血液的装置,该透析器由半透膜分隔成第一和第二腔室,其中第一腔室设置在透析液通路中,第二腔室可连接血液 通过血液流入管道和血液流出管道,新鲜透析液体的进料,废透析液的排出物,用于分别估计血液流出管道中的血流QBlood的装置, 用于确定透析流体通路中的流动QDialysate的装置,以及设置在所述放电中用于估计流过所述放电的废透析液的吸收剂量的测量装置,其中所述测量装置具有至少一个辐射源和检测器 用于检测电磁辐射强度的系统。 其中提供了一种存储器,其中存储用于吸收ABlood的公式A Blood =(A透析液·Q透析液Q血液)和用于估计血液流入导管中的吸收ABlood的运算单元, 吸收ADDIysate,流量QDialysate和流量QBlood。
    • 9. 发明授权
    • Apparatus for extracorporeal blood treatment
    • 体外血液治疗仪器
    • US09220827B2
    • 2015-12-29
    • US13816968
    • 2011-08-17
    • Joern MeibaumStefan MollAlex Castellarnau
    • Joern MeibaumStefan MollAlex Castellarnau
    • A61M37/00A61M1/14A61M1/16G01N21/33
    • A61M1/14A61M1/16A61M1/1609A61M1/1613A61M1/361A61M1/3612A61M2202/0498A61M2205/3306A61M2205/3313A61M2205/52G01N21/33
    • The invention describes an apparatus for extracorporeal blood treatment with a dialyzer which is separated by a semipermeable membrane in to a first and second chamber (29, 30), wherein the first chamber (29) is arrange in a dialysate pathway and the second chamber (30) is connectable to the blood circulation of a patient by means of a blood supply conduit (32) and a blood return conduit (31), an inlet (20) for fresh dialysate, an outlet (30) for spent dialysate, a measuring device (37) arranged in the outlet (36), wherein said measuring device (37) has at least one radiation source consisting of several light sources (1) for electromagnetic radiation. The invention is characterized in that the measuring device (37) is designed to generate substantially monochromatic electromagnetic radiation of different wavelengths, and to lead only one of these wavelength (at the same time) though the outlet (36) for spent dialysate, wherein at least one detector system (5) is provided for detection of the intensity or the absorption of the substantially monochromatic electromagnetic radiation passing through the outlet (36) for spent dialysate.
    • 本发明描述了一种用透析器进行体外血液处理的装置,其由半透膜分隔到第一和第二腔室(29,30)中,其中第一腔室(29)布置在透析液通路中,第二腔室 30)可通过血液供应管道(32)和血液回流管道(31),用于新鲜透析液的入口(20),用于透析液的出口(30),血液透析液 设置在所述出口(36)中的装置(37),其中所述测量装置(37)具有由用于电磁辐射的多个光源(1)组成的至少一个辐射源。 本发明的特征在于,测量装置(37)被设计成产生不同波长的基本上单色的电磁辐射,并且仅通过用于废透析液的出口(36)仅引导这些波长(同时)中的一个波长(其中在 提供了至少一个检测器系统(5),用于检测通过用于透析液的出口(36)的基本上单色的电磁辐射的强度或吸收。