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1. 发明申请

US20120252926A1 LATENTLY REACTIVE POLYURETHANE DISPERSION WITH ACTIVATABLE CROSSLINKING 有权
标题翻译：最终的反应性聚氨酯分散与激活交联
公开(公告)号：US20120252926A1
公开(公告)日：2012-10-04
申请号：US13436050
申请日：2012-03-30
申请人： Axel MEYER , Maria Teresa Hechavarria Fonseca , Tina Schröder-Grimonpont , Stefan Dahmen , Christian Beil , Karl-Heinz Schumacher , Thomas Abend
发明人： Axel MEYER , Maria Teresa Hechavarria Fonseca , Tina Schröder-Grimonpont , Stefan Dahmen , Christian Beil , Karl-Heinz Schumacher , Thomas Abend
IPC分类号： C09D5/14 , B29C65/52 , C09J175/12 , C08J7/18 , C08L75/12 , C09D175/12
CPC分类号： C08G18/6692 , B29C65/1416 , B29C65/1419 , B29C65/1422 , B29C65/1425 , B29C65/48 , B29C65/4815 , B29C65/483 , B29C65/4845 , B29C65/4865 , C08G18/0823 , C08G18/0828 , C08G18/10 , C08G18/12 , C08G18/725 , C08G18/798 , C09D175/04 , C09J175/04 , C08G18/3253 , C08G18/3872
摘要： A description is given of an aqueous polymer dispersion comprising at least one polyurethane, dispersed in aqueous phase and having one or more uretdione groups, and at least one solid polyamine with a deactivated surface, said dispersion being useful as an adhesive, coating material or sealant or for producing adhesive, coating or sealing compositions. The compositions can be activated thermally or by electromagnetic radiation.
摘要翻译：描述了包含至少一种分散在水相中并具有一个或多个脲二酮基团的聚氨酯和至少一种具有失活表面的固体多胺的聚合物水分散体，所述分散体可用作粘合剂，涂料或密封剂或用于生产粘合剂，涂料或密封组合物。组合物可以热或通过电磁辐射活化。

2. 发明申请

US20120077044A1 BIODISINTEGRATABLE COMPOSITE FOILS 有权
标题翻译：生物可降解复合材料
公开(公告)号：US20120077044A1
公开(公告)日：2012-03-29
申请号：US13191982
申请日：2011-07-27
申请人： Cornelis Petrus BEYERS , Heiko Diehl , Stefan Dahmen , Volker Kriegisch , Ulrike Licht , Axel Meyer , Motonori Yamamoto
发明人： Cornelis Petrus BEYERS , Heiko Diehl , Stefan Dahmen , Volker Kriegisch , Ulrike Licht , Axel Meyer , Motonori Yamamoto
IPC分类号： B32B37/12 , B32B27/40 , B05D7/24
CPC分类号： C09D175/06 , B32B37/12 , B32B37/14 , B32B2037/148 , B32B2307/7163 , B32B2317/12 , B32B2553/00 , C08G18/0823 , C08G18/10 , C08G18/12 , C08G18/4216 , C08G18/4238 , C08G18/6659 , C08G18/792 , C08G2170/80 , C08G2230/00 , C09J175/06 , Y10T428/31551 , C08G18/3234 , C08G18/3821
摘要： The use of an aqueous polyurethane dispersion adhesive is described for producing biodisintegratable composite foils where at least two substrates are adhesive-bonded to one another with use of the polyurethane dispersion adhesive, where at least one of the substrates is a biodisintegrable polymer foil. At least 60% by weight of the polyurethane is composed of diisocyanates, polyesterdiols, and at least one bifunctional carboxylic acid selected from dihydroxycarboxylic acids and diaminocarboxylic acids.
摘要翻译：描述了使用水性聚氨酯分散体粘合剂用于生产生物可分解复合箔，其中使用聚氨酯分散粘合剂将至少两个基底彼此粘合，其中至少一个基底是生物可分解聚合物箔。至少60重量％的聚氨酯由二异氰酸酯，聚酯二醇和至少一种选自二羟基羧酸和二氨基羧酸的双官能羧酸组成。

3. 发明授权

US07109349B2 Process for obtaining Cizolirtine and its enantiomers 失效
标题翻译：获得Cizolirtine及其对映异构体的方法
公开(公告)号：US07109349B2
公开(公告)日：2006-09-19
申请号：US11041637
申请日：2005-01-24
申请人： Antoni Torrens Jover , Helmut H. Buschmann , Stefan Dahmen , Matthias Lormann
发明人： Antoni Torrens Jover , Helmut H. Buschmann , Stefan Dahmen , Matthias Lormann
IPC分类号： C07D231/12
CPC分类号： C07D231/12
摘要： A process is described for the preparation of a precursor alcohol of Cizolirtine, (±)-2-[phenyl(1-methyl-1H-pyrazol-5-yl)methoxy]-N,N-dimethylethanamine and its enantiomers. The process involves the asymmetric addition of a metalated phenyl reagent to a pyrazolcarbaldehyde in the presence of a chiral ligand to yield chiral alcohols. The chiral alcohols are further O-alkylated to yield Cizolirtine or its enantiomers.
摘要翻译：描述了制备Cizolirtine（±）-2- [苯基（1-甲基-1H-吡唑-5-基）甲氧基] -N，N-二甲基乙胺及其对映异构体的前体醇的方法。该方法包括在手性配体存在下将金属化苯基试剂不对称加成到吡唑甲醛中以产生手性醇。手性醇进一步O-烷基化以得到西来甜胺或其对映异构体。

4. 发明授权

US08841369B2 Latently reactive polyurethane dispersion with activatable crosslinking 有权
标题翻译：具有可活化交联的潜在反应性聚氨酯分散体
公开(公告)号：US08841369B2
公开(公告)日：2014-09-23
申请号：US13436050
申请日：2012-03-30
申请人： Axel Meyer , Maria Teresa Hechavarria Fonseca , Tina Schroeder-Grimonpont , Stefan Dahmen , Christian Beil , Karl-Heinz Schumacher , Thomas Abend
发明人： Axel Meyer , Maria Teresa Hechavarria Fonseca , Tina Schroeder-Grimonpont , Stefan Dahmen , Christian Beil , Karl-Heinz Schumacher , Thomas Abend
IPC分类号： C08K5/17 , C08K5/23 , C08G18/10 , C08G18/08 , C08G18/79 , C08G18/12 , C08G18/66 , C08G18/72 , C09D175/04 , C09J175/04 , B29C65/48
CPC分类号： C08G18/6692 , B29C65/1416 , B29C65/1419 , B29C65/1422 , B29C65/1425 , B29C65/48 , B29C65/4815 , B29C65/483 , B29C65/4845 , B29C65/4865 , C08G18/0823 , C08G18/0828 , C08G18/10 , C08G18/12 , C08G18/725 , C08G18/798 , C09D175/04 , C09J175/04 , C08G18/3253 , C08G18/3872
摘要： A description is given of an aqueous polymer dispersion comprising at least one polyurethane, dispersed in aqueous phase and having one or more uretdione groups, and at least one solid polyamine with a deactivated surface, said dispersion being useful as an adhesive, coating material or sealant or for producing adhesive, coating or sealing compositions. The compositions can be activated thermally or by electromagnetic radiation.
摘要翻译：描述了包含至少一种分散在水相中并具有一个或多个脲二酮基团的聚氨酯和至少一种具有失活表面的固体多胺的聚合物水分散体，所述分散体可用作粘合剂，涂层材料或密封剂或用于生产粘合剂，涂料或密封组合物。组合物可以热或通过电磁辐射活化。

5. 发明申请

US20090247771A1 PROCESS FOR OBTAINING ENANTIOMERS OF DULOXETINE PRECURSORS 审中-公开
标题翻译：获得杜鹃素前体成分的方法
公开(公告)号：US20090247771A1
公开(公告)日：2009-10-01
申请号：US12280084
申请日：2007-02-27
申请人： Helmut Heinrich Buschmann , Antoni Torrens Jover , Matthias Lormann , Stefan Dahmen
发明人： Helmut Heinrich Buschmann , Antoni Torrens Jover , Matthias Lormann , Stefan Dahmen
IPC分类号： C07D333/16
CPC分类号： C07D333/24 , C07D333/12 , C07D333/14 , Y02P20/55
摘要： The present invention is directed to a process for the preparation of an enantiomerically enriched compound of formula II wherein, R1, R2 and R3 are each independently selected from hydrogen, halogen, substituted or unsubstituted lower alkyl or substituted or unsubstituted aryl; X is —C(═O)-Z or —Y, wherein —Y is selected from —CH2—OR4, —CH2-halogen or —CH2—NR6R7; wherein Z is selected from —NR6R7 or —OR5, wherein R5 is selected from hydrogen, substituted or unsubstituted lower alkyl or ester activating group; R4 is selected from hydrogen, hydroxyl protecting group or hydroxyl activating group; R6 and R7 are each independently selected from hydrogen, amino protecting group, amido protecting group or substituted or unsubstituted lower alkyl; or a pharmaceutically acceptable salt, complex or solvate thereof; which comprises an enantioselective addition with a thienyl zinc reagent, in the presence of a chiral ligand.
摘要翻译：本发明涉及制备对映体富集的式II化合物的方法，其中R 1，R 2和R 3各自独立地选自氢，卤素，取代或未取代的低级烷基或取代或未取代的芳基; X是-C（-O）-Z或-Y，其中-Y选自-CH2-OR4，-CH2-卤素或-CH2-NR6R7; 其中Z选自-NR 6 R 7或-OR 5，其中R 5选自氢，取代或未取代的低级烷基或酯活化基团; R4选自氢，羟基保护基或羟基活化基团; R6和R7各自独立地选自氢，氨基保护基，酰氨基保护基或取代或未取代的低级烷基; 或其药学上可接受的盐，复合物或溶剂化物; 其包括在手性配体存在下用噻吩锌试剂进行对映选择性加成。

6. 发明申请

US20060135788A1 PROCESS FOR OBTAINING CIZOLIRTINE AND ITS ENANTIOMERS 失效
标题翻译：获得CIZOLIRTINE及其成份的方法
公开(公告)号：US20060135788A1
公开(公告)日：2006-06-22
申请号：US11041637
申请日：2005-01-24
申请人： Antoni Jover , Helmut Buschmann , Stefan Dahmen , Matthias Lormann
发明人： Antoni Jover , Helmut Buschmann , Stefan Dahmen , Matthias Lormann
IPC分类号： C07D231/12
CPC分类号： C07D231/12
摘要： A process is described for the preparation of a precursor alcohol of Cizolirtine, (±)-2-[phenyl(1-methyl-1H-pyrazol-5-yl)methoxy]-N,N-dimethylethanamine and its enantiomers. The process involves the asymmetric addition of a metalated phenyl reagent to a pyrazolcarbaldehyde in the presence of a chiral ligand to yield chiral alcohols. The chiral alcohols are further O-alkylated to yield Cizolirtine or its enantiomers.
摘要翻译：描述了制备Cizolirtine（±）-2- [苯基（1-甲基-1H-吡唑-5-基）甲氧基] -N，N-二甲基乙胺及其对映异构体的前体醇的方法。该方法包括在手性配体存在下将金属化苯基试剂不对称加成到吡唑甲醛中以产生手性醇。手性醇进一步O-烷基化以得到西来甜胺或其对映异构体。

7. 发明授权

US08956497B2 Biodisintegratable composite foils 有权
标题翻译：生物整合复合箔
公开(公告)号：US08956497B2
公开(公告)日：2015-02-17
申请号：US13191982
申请日：2011-07-27
申请人： Cornelis Petrus Beyers , Heiko Diehl , Stefan Dahmen , Volker Kriegisch , Ulrike Licht , Axel Meyer , Motonori Yamamoto
发明人： Cornelis Petrus Beyers , Heiko Diehl , Stefan Dahmen , Volker Kriegisch , Ulrike Licht , Axel Meyer , Motonori Yamamoto
IPC分类号： C09J4/00 , C09J101/00 , C09J201/00 , B32B27/00 , B32B27/40 , B32B37/12 , C09D175/06 , B32B37/14 , C08G18/66 , C08G18/79 , C08G18/08 , C08G18/10 , C08G18/12 , C08G18/42 , C09J175/06
CPC分类号： C09D175/06 , B32B37/12 , B32B37/14 , B32B2037/148 , B32B2307/7163 , B32B2317/12 , B32B2553/00 , C08G18/0823 , C08G18/10 , C08G18/12 , C08G18/4216 , C08G18/4238 , C08G18/6659 , C08G18/792 , C08G2170/80 , C08G2230/00 , C09J175/06 , Y10T428/31551 , C08G18/3234 , C08G18/3821
摘要： A method for producing biodisintegratable composite foils with an aqueous polyurethane dispersion adhesive. The method involves adhesive-bonding a first substrate to a second substrate with use of the aqueous polyurethane dispersion adhesive. At least one of the first substrate and the second substrate is made of a biodisintegratable polymer foil, and at least 60% by weight of the polyurethane contains diisocyanates, polyesterdiols, and bifunctional carboxylic acids. The bifunctional carboxylic acids are dihydroxycarboxylic acids or diaminocarboxylic acids.
摘要翻译：一种用水性聚氨酯分散体粘合剂生产生物可分解复合箔的方法。该方法包括使用水性聚氨酯分散体粘合剂将第一基底粘合到第二基底上。第一衬底和第二衬底中的至少一个由生物可分解聚合物箔制成，并且至少60重量％的聚氨酯含有二异氰酸酯，聚酯二醇和双官能羧酸。双官能羧酸是二羟基羧酸或二氨基羧酸。

8. 发明授权

US08790753B2 Rubber material with barrier material made of cycloolefin copolymers 有权
标题翻译：具有由环烯烃共聚物制成的阻隔材料的橡胶材料
公开(公告)号：US08790753B2
公开(公告)日：2014-07-29
申请号：US13370987
申请日：2012-02-10
申请人： Kevin Müller , Stefan Dahmen
发明人： Kevin Müller , Stefan Dahmen
IPC分类号： B05D1/02 , B05D3/00 , C08L65/00
CPC分类号： C09D145/00 , B29D30/0681 , B29D2030/0682 , B32B1/08 , B32B25/16 , B32B27/325 , B32B2605/08 , B60C1/0008 , B60C1/0041 , C08L2201/50 , Y10T152/10495 , Y10T428/31837
摘要： A rubber material is described, modified with a barrier material in the form of a copolymer which can be produced via ring-opening metathesis polymerization of a) at least one olefin monomer selected from the group consisting of monocyclic olefin monomers having one or two endocyclic C—C double bonds and bicyclic olefin monomers having one endocyclic C—C double bond and b) at least one polycyclic olefin monomer having at least two C—C double bonds. The barrier material can be used to reduce the gas permeability of the rubber material.
摘要翻译：描述了一种橡胶材料，其以共聚物形式的阻隔材料进行改性，该共聚物可以通过开环易位聚合制备，a）至少一种烯烃单体，其选自具有一个或两个内环C的单环烯烃单体 -C双键和具有一个环内C-C双键的双环烯烃单体和b）至少一种具有至少两个C-C双键的多环烯烃单体。阻挡材料可用于降低橡胶材料的气体渗透性。

9. 发明申请

US20120205022A1 RUBBER MATERIAL WITH BARRIER MATERIAL MADE OF CYCLOOLEFIN COPOLYMERS 有权
标题翻译：橡胶材料与环氧树脂共聚物的阻挡材料
公开(公告)号：US20120205022A1
公开(公告)日：2012-08-16
申请号：US13370987
申请日：2012-02-10
申请人： Kevin Müller , Stefan Dahmen
发明人： Kevin Müller , Stefan Dahmen
IPC分类号： C08F232/08 , C09D145/00 , B05D3/00 , B60C9/02 , B29D30/06 , B05D1/02 , B32B25/08 , B60C1/00
CPC分类号： C09D145/00 , B29D30/0681 , B29D2030/0682 , B32B1/08 , B32B25/16 , B32B27/325 , B32B2605/08 , B60C1/0008 , B60C1/0041 , C08L2201/50 , Y10T152/10495 , Y10T428/31837
摘要： A rubber material is described, modified with a barrier material in the form of a copolymer which can be produced via ring-opening metathesis polymerization of a) at least one olefin monomer selected from the group consisting of monocyclic olefin monomers having one or two endocyclic C—C double bonds and bicyclic olefin monomers having one endocyclic C—C double bond and b) at least one polycyclic olefin monomer having at least two C—C double bonds. The barrier material can be used to reduce the gas permeability of the rubber material.
摘要翻译：描述了一种橡胶材料，其以共聚物形式的阻隔材料进行改性，该共聚物可以通过开环易位聚合制备，a）至少一种烯烃单体，其选自具有一个或两个内环C的单环烯烃单体 -C双键和具有一个环内C-C双键的双环烯烃单体和b）至少一种具有至少两个C-C双键的多环烯烃单体。阻挡材料可用于降低橡胶材料的气体渗透性。

10. 发明授权

US07078531B2 Process for obtaining enantiomers of thienylazolylalcoxyethanamines 失效
标题翻译：获得噻吩并噻唑基乙酰胺的对映异构体的方法
公开(公告)号：US07078531B2
公开(公告)日：2006-07-18
申请号：US11041638
申请日：2005-01-24
申请人： Antoni Torrens Jover , Helmut H. Buschmann , Stefan Dahmen , Matthias Lormann
发明人： Antoni Torrens Jover , Helmut H. Buschmann , Stefan Dahmen , Matthias Lormann
IPC分类号： C07D231/12
CPC分类号： C07D409/06
摘要： A process is described for the preparation of a precursor alcohol of (±)-2-[thienyl(1-methyl-1H-pyrazol-5-yl)methoxy]-N,N-dimethyletanamine and in general for thienylazolylalcoxyethanamines and their enantiomers. The process involves asymmetric addition of a metalated thienyl reagent to a pyrazolcarbaldehyde in the presence of a chiral ligand to yield chiral alcohols. The chiral alcohols are further O-alkylated to yield the corresponding pharmaceutically active thienylazolylalcoxyethanamines.
摘要翻译：描述了制备（±）-2- [噻吩基（1-甲基-1H-吡唑-5-基）甲氧基] -N，N-二甲基乙胺的前体醇的方法，通常用于噻吩并噻唑基醛乙氧基胺及其对映异构体。该方法包括在手性配体的存在下将金属化噻吩试剂不对称加成到吡唑甲醛中以产生手性醇。手性醇进一步O-烷基化，得到相应的药学活性噻吩并噻唑基乙醇胺。

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