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1. 发明申请

US20060189673A1 Phenylazole compound, production process therefor and antioxidant 审中-公开
标题翻译：苯唑化合物，其生产工艺及抗氧化剂
公开(公告)号：US20060189673A1
公开(公告)日：2006-08-24
申请号：US10553108
申请日：2004-04-13
申请人： Nobuo Mochizuki , Nobuhiro Umeda , Seiichi Uchida , Seiichi Ikeyama , Shiro Tsubokura , Mitsumasa Takada
发明人： Nobuo Mochizuki , Nobuhiro Umeda , Seiichi Uchida , Seiichi Ikeyama , Shiro Tsubokura , Mitsumasa Takada
IPC分类号： A61K31/4164 , A61K31/415
CPC分类号： C07D405/12 , A61K31/4155 , A61K31/4178 , C07D409/12 , C07D411/12
摘要： The present invention relates to a compound represented by formula (1): (wherein R represents a hydrogen atom or a C1-6 alkyl group which may be substituted, A represents an imidazolyl group or a pyrazolyl group, B represents a group represented by the following formula: (wherein R5 and R6 each independently represents a hydrogen atom, a cyano group, a hydroxyl group, a halogen atom, a C1-6 alkyl group, a C1-6 alkoxy group, or the like, k represents 0 or an integer of 1 to 15, and R5 and R6 may be identical or different from each other, when k is 2 or more), and Z represents a substituted chroman-2-yl group, a substituted 2,3-dihydrobenzofuran-2-yl, a substituted thiochroman-2-yl group, a substituted 2,3-dihydrobenzothiophene-2-yl group, or a substituted 1,3-benzoxathiol-2-yl group).
摘要翻译：本发明涉及由式（1）表示的化合物：其中R表示氢原子或可被取代的C 1-6烷基，A表示咪唑基或吡唑基 B表示由下式表示的基团：（其中，R 5和R 6各自独立地表示氢原子，氰基，羟基，卤素原子，C 1-6烷基， C 1-6烷氧基等，k表示0或1〜15的整数，R 5和R 6可以相同或不同，k为2以上时） Z表示取代的苯并二氢吡喃-2-基，取代的2,3-二氢苯并呋喃-2-基，取代的二氢苯并噻喃-2-基，取代的2,3-二氢苯并噻吩-2-基或取代的 1,3-苯并硫代-2-基）。

2. 发明授权

US06184297B2 Ethylene copolymer composition 失效
标题翻译：乙烯共聚物组成
公开(公告)号：US06184297B2
公开(公告)日：2001-02-06
申请号：US08798907
申请日：1997-02-12
申请人： Mamoru Takahashi , Seiichi Ikeyama , Akira Todo , Toshiyuki Tsutsui , Seiji Ohta , Hajime Inagaki
发明人： Mamoru Takahashi , Seiichi Ikeyama , Akira Todo , Toshiyuki Tsutsui , Seiji Ohta , Hajime Inagaki
IPC分类号： C08L2308
CPC分类号： C08L23/0815 , C08F10/02 , C08F110/02 , C08F210/16 , C08F210/18 , C08L23/06 , C08L23/10 , C08L23/12 , C08L23/14 , C08L23/16 , C08L23/20 , C08L23/22 , C08L51/06 , C08L2205/02 , Y10S526/943 , C08F2/00 , C08L2666/24 , C08L2666/06 , C08F2500/12 , C08F2500/11 , C08F2500/08 , C08F210/14 , C08F210/08 , C08F232/00 , C08F2500/25 , C08L2666/04
摘要： An ethylene copolymer composition comprising an ethylene/&agr;-olefin copolymer [A1] obtained by using a catalyst for olefin polymerization containing an organoaluminum oxy-compound (a) and at least two kinds of specific metallocene compounds (b), and one (co)polymer selected from the group consisting of [B1] a low-density polyethylene obtained by high-pressure radical polymerization, [B2] a crystalline polyolefin and [B3] an olefin type elastomer. An ethylene copolymer composition comprising an ethylene/&agr;-olefin copolymer [A2] having specific properties, and one (co)polymer selected from the group consisting of [B1] a low-density polyethylene obtained by high-pressure radical polymerization, [B2] a crystalline polyolefin and [B3] an olefin type elastomer.
摘要翻译：一种乙烯共聚物组合物，其包含通过使用含有有机铝氧化合物（a）和至少两种特定茂金属化合物（b）的烯烃聚合催化剂获得的乙烯/α-烯烃共聚物[A1]和一种（共）选自[B1]通过高压自由基聚合得到的低密度聚乙烯的聚合物，[B2]结晶聚烯烃和[B3]烯烃类弹性体。包含具有特定性能的乙烯/α-烯烃共聚物[A2]和一种选自[B1]通过高压自由基聚合得到的低密度聚乙烯的（共）聚合物的乙烯共聚物组合物，[B2] 结晶聚烯烃和[B3]烯烃类弹性体。

3. 发明申请

US20060194872A1 Diamine derivative, production process therefor and antioxidant 失效
标题翻译：二胺衍生物，生产工艺及抗氧化剂
公开(公告)号：US20060194872A1
公开(公告)日：2006-08-31
申请号：US10552015
申请日：2004-04-13
申请人： Nobuhiro Umeda , Nobuo Mochizuki , Seiichi Uchida , Seiichi Ikeyama
发明人： Nobuhiro Umeda , Nobuo Mochizuki , Seiichi Uchida , Seiichi Ikeyama
IPC分类号： A61K31/353 , A61K31/343
CPC分类号： C07D307/79 , C07D311/70
摘要： The present invention relates to a compound represented by formula (1): (wherein, R1, R2, R3 and R4 respectively and independently represent a hydrogen atom or a C1-6 alkyl group, and n represents an integer of 1 or 2) and a production process thereof, as well as an antioxidant that contains the compound as its active ingredient, and a kidney disease treatment agent, cerebrovascular disorder treatment agent, retina oxidative disorder inhibitor and lipoxygenase inhibitor that contain the antioxidant.
摘要翻译：本发明涉及由式（1）表示的化合物：其中，R 1，R 2，R 3和R 4分别独立地表示氢原子或C 1-6烷基，n表示 1或2的整数）及其制备方法，以及含有该化合物作为其活性成分的抗氧化剂，以及含有抗氧化剂的肾脏疾病治疗剂，脑血管障碍治疗剂，视网膜氧化障碍抑制剂和脂氧合酶抑制剂。

4. 发明授权

US06894120B2 Ethylene copolymer composition 失效
标题翻译：乙烯共聚物组成
公开(公告)号：US06894120B2
公开(公告)日：2005-05-17
申请号：US10819284
申请日：2004-04-07
申请人： Mamoru Takahashi , Akira Todo , Seiichi Ikeyama , Toshiyuki Tsutsui , Shinya Matsunaga , Norio Kaneshige
发明人： Mamoru Takahashi , Akira Todo , Seiichi Ikeyama , Toshiyuki Tsutsui , Shinya Matsunaga , Norio Kaneshige
IPC分类号： C08L23/06 , C08L23/08 , C08L23/00
CPC分类号： C08L23/0815 , C08L23/06 , C08L2314/06 , Y10S526/943 , Y10T428/1397 , C08L2666/04
摘要： An ethylene copolymer composition comprising an ethylene/α-olefin copolymer, A-4, of ethylene with an α-olefin of 3 to 20 carbon atoms in an amount of 65-98% by weight, whose melt tension, MT, at 190° C. and MFR satisfy the relation MT>2.2×MFR−0.84, and at least one crystalline polyolefin, B-2, in an amount of 1-40% by weight selected from the group consisting of, B-I, an ethylene homopolymer or a copolymer of ethylene with an α-olefin of 3 to 20 carbon atoms, prepared using a non-metallocene type catalyst, B-II, a propylene hompolymer or a copolymer of propylene with at least one olefin selected from ethylene and an α-olefin of 4 to 20 carbon atoms, and, B-III, a homopolymer of an α-olefin of 4 to 20 carbon atoms or a copolymer of α-olefins of 4 to 20 carbon atoms, and articles made from the composition.
摘要翻译：一种乙烯共聚物组合物，其包含乙烯/α-烯烃共聚物A-4，其乙烯与3-20个碳原子的α-烯烃的重量百分比为65-98％，其熔体张力MT在190℃ C.和MFR满足MT> 2.2×MFR -0.84的关系，和至少一种结晶聚烯烃B-2，其量为1-40％（重量），选自BI 乙烯均聚物或乙烯与3-20个碳原子的α-烯烃的共聚物，其使用非茂金属型催化剂，B-II，丙烯均聚物或丙烯与至少一种选自乙烯的烯烃的共聚物制备和4至20个碳原子的α-烯烃，和B-III，4-20个碳原子的α-烯烃的均聚物或4-20个碳原子的α-烯烃的共聚物，以及由组成。

5. 发明授权

US5674945A Ethylene copolymer composition 失效
标题翻译：乙烯共聚物组成
公开(公告)号：US5674945A
公开(公告)日：1997-10-07
申请号：US429010
申请日：1995-04-26
申请人： Mamoru Takahashi , Akira Todo , Seiichi Ikeyama , Toshiyuki Tsutsui , Shinya Matsunaga , Norio Kaneshige
发明人： Mamoru Takahashi , Akira Todo , Seiichi Ikeyama , Toshiyuki Tsutsui , Shinya Matsunaga , Norio Kaneshige
IPC分类号： C08L23/06 , C08L23/08
CPC分类号： C08L23/0815 , C08L23/06 , C08L2314/06 , Y10S526/943 , Y10T428/1397
摘要： Ethylene copolymer compositions comprise: an ethylene/.alpha.-olefin copolymer component comprising at least one ethylene/.alpha.-olefin copolymer having a density within a specific range, a melt flow rate (MFR) within a specific range, an amount of an n-decane-soluble portion within a specific range and a melt tension (MT) that satisfies a specific relation with the MFR; and a (co)polymer component comprising one (co)polymer selected from the group consisting of a low-density polyethylene obtained by high-pressure radical polymerization, a crystalline polyolefin and an olefin elastomer. The ethylene copolymer compositions are excellent in heat stability and moldability, and able to form films of high transparency, high mechanical strength and anti-blocking resistance.
摘要翻译：乙烯共聚物组合物包括：乙烯/α-烯烃共聚物组分，其包含至少一种密度在特定范围内的乙烯/α-烯烃共聚物，特定范围内的熔体流动速率（MFR），正癸烷的量 - 特定范围内的熔融张力（MT），和MFR的特定关系; 和（共）聚合物组分，其包含选自由高压自由基聚合获得的低密度聚乙烯，结晶聚烯烃和烯烃弹性体的一种（共）聚合物。乙烯共聚物组合物的热稳定性和成型性优异，能够形成高透明性，高机械强度和抗粘连性的膜。

6. 发明授权

US5459217A Ethylene/alpha-olefin copolymer 失效
标题翻译：乙烯/α-烯烃共聚物
公开(公告)号：US5459217A
公开(公告)日：1995-10-17
申请号：US345793
申请日：1994-11-22
申请人： Akira Todo , Mamoru Takahashi , Seiichi Ikeyama , Toshiyuki Tsutsui
发明人： Akira Todo , Mamoru Takahashi , Seiichi Ikeyama , Toshiyuki Tsutsui
IPC分类号： C08F210/16 , C08J5/18 , C08F10/02 , C08F210/02
CPC分类号： C08J5/18 , C08F210/16 , C08J2323/08
摘要： The present invention provides an ethylene/.alpha.-olefin copolymer comprising constituent units (a) derived from ethylene and constituent units (b) derived from an .alpha.-olefin having 3 to 20 carbon atoms, the ethylene copolymer being characterized in that(A) the ethylene/.alpha.-olefin copolymer has a density (d) of 0.88 to 0.95 g/cm.sup.3 ;(B) the ethylene/.alpha.-olefin copolymer has a MFR of 0.01 to 200 g/10 min as measured at a temperature of 190.degree. C. and a load of 2.16 kg;(C) the temperature (Tm) at which the exothermic curve of the ethylene/.alpha.-olefin copolymer measured by a differential scanning calorimeter (DSC) shows the highest peak and the density (d) satisfy the relationTm 75.times.MFR; and(F) the melt tension (MT) at 190.degree. C. and MFR of the copolymer satisfy the relation,3.98.times.MFR.sup.-0.66 >MT>2.times.MFR.sup.-0.65.
摘要翻译：本发明提供一种乙烯/α-烯烃共聚物，其包含衍生自乙烯的构成单元（a）和衍生自具有3-20个碳原子的α-烯烃的构成单元（b），所述乙烯共聚物的特征在于（A）乙烯/α-烯烃共聚物的密度（d）为0.88〜0.95g / cm3; （B）乙烯/α-烯烃共聚物在190℃的温度和2.16kg的负荷下测得的MFR为0.01至200g / 10min; （C）通过差示扫描量热计（DSC）测定的乙烯/α-烯烃共聚物的放热曲线的温度（Tm）显示最高峰，密度（d）满足Tm <400d-250的关系; （D）在室温下正癸烷可溶成分的量分数（W）满足关系式，在MFR≤10g/ 10分钟的情况下，W <80×exp（-100（d-0.88））+0.1，在MFR≥10g/ 10min的情况下，W <80x（MFR-9）0.35×exp（-100（d-0.88））+ 0.1; （E）当熔融共聚物在190℃的剪切应力达到2.4×10 6达因/ cm 2时给出的剪切速率所限定的流动指数（FI）满足关系式，FI> 75xMFR; 和（F）190℃下的熔体张力（MT），共聚物的MFR满足关系式3.98xMFR-0.66> MT> 2xMFR-0.65。

7. 发明授权

US5290896A Ethylene/pentene-1 copolymer, and ethylene/pentene-1 copolymer composition 失效
标题翻译：乙烯/戊烯-1共聚物和乙烯/戊烯-1共聚物组合物
公开(公告)号：US5290896A
公开(公告)日：1994-03-01
申请号：US661256
申请日：1991-02-27
申请人： Mamoru Kioka , Tsuneo Yashiki , Takashi Ueda , Masaki Kohyama , Masaya Yamada , Seiichi Ikeyama , Yoshinori Akana , Kenji Iwata , Satoshi Matsumoto , Hideki Sakai
发明人： Mamoru Kioka , Tsuneo Yashiki , Takashi Ueda , Masaki Kohyama , Masaya Yamada , Seiichi Ikeyama , Yoshinori Akana , Kenji Iwata , Satoshi Matsumoto , Hideki Sakai
IPC分类号： C08F210/02 , C08F210/16 , C08J5/18 , C08K5/00 , C08K5/524 , C08L23/08 , C08F210/14
CPC分类号： C08J5/18 , C08F210/16 , C08K5/005 , C08J2323/08 , C08L23/0815
摘要： The present invention relates to a novel ethylene/pentene-1 copolymer whose molded film has a good balance between impact resistance and tear properties and high transparency, also is prominently reduced in a variation of the transparency even after subjected to a heat treatment, and further shows high blocking resistance, provided that the copolymer fulfills specific requisites. The invention also relates to a process for the preparation of the above-mentioned ethylene/pentene-1 copolymer and a formulation of the ethylene/pentene-1 copolymer composition using a stabilizer. According to the invention, there can be obtained an ethylene/pentene-1 copolymer composition which is excellent in heat stability in the molding stage, long-term heat stability and weatherability.
摘要翻译：本发明涉及一种新型的乙烯/戊烯-1共聚物，其成型膜在抗冲击性和撕裂性能以及高透明度之间具有良好的平衡，即使经受热处理后透明性的变化也显着降低，并且进一步显示出高抗粘连性，只要共聚物满足特定的要求即可。本发明还涉及制备上述乙烯/戊烯-1共聚物的方法和使用稳定剂的乙烯/戊烯-1共聚物组合物的配方。根据本发明，可以获得在成型阶段的热稳定性优异，长期的热稳定性和耐气候性的乙烯/戊烯-1共聚物组合物。

8. 发明授权

US07553837B2 Phenylazole compounds production process and antioxidants 失效
标题翻译：苯唑化合物生产工艺及抗氧化剂
公开(公告)号：US07553837B2
公开(公告)日：2009-06-30
申请号：US10566820
申请日：2004-07-30
申请人： Nobuhiro Umeda , Nobuo Mochizuki , Seiichi Uchida , Mitsumasa Takada , Seiichi Ikeyama , Shiro Tsubokura , Yasuyuki Shiinoki , Fumie Shirato , Hiroko Momoe
发明人： Nobuhiro Umeda , Nobuo Mochizuki , Seiichi Uchida , Mitsumasa Takada , Seiichi Ikeyama , Shiro Tsubokura , Yasuyuki Shiinoki , Fumie Shirato , Hiroko Momoe
IPC分类号： A61K31/497 , A61K31/445 , A01N43/40 , C07D241/04 , C07D295/00 , C07D211/00
CPC分类号： C07D471/04 , C07D405/12 , C07D405/14
摘要： The present invention is directed to compounds represented by the formula (1): B-D-Z (1), wherein B represent the following formula (B-1), (B-2) or (B-3); A represents an optionally substituted imidazole or pyrazole group; E represents the following formula (1a); X represents an oxygen atom, the formula: SOu, or the formula: N—R9; Y represents a carbon atom or a nitrogen atom; D represents an oxygen atom, a sulfur atom or the formula (1a); Z represents (a chroman-2-yl group, a chroman-4-yl group, a 2,3-dihydrobenzofuran-2-yl group, a 2,3-dihydrobenzofuran-3-yl group, etc.) which is substituted with NHR10 or OR11)] or pharmaceutically acceptable salts thereof, and to antioxidants, therapeutic agents for kidney diseases or cerebrovascular disorder, and retinal oxidative damage inhibitors, which include the compounds as the active ingredient.
摘要翻译：本发明涉及由式（1）表示的化合物：B-D-Z（1），其中B表示下式（B-1），（B-2）或（B-3）; A表示任选取代的咪唑或吡唑基; E表示下式（1a）; X表示氧原子，分子式为：SOu或式：N-R 9; Y表示碳原子或氮原子; D表示氧原子，硫原子或式（1a）; Z表示（苯并二氢吡喃-2-基，苯并二氢吡喃-4-基，2,3-二氢苯并呋喃-2-基，2,3-二氢苯并呋喃-3-基等），其被 NHR10或OR11）]或其药学上可接受的盐，以及抗氧化剂，肾脏疾病或脑血管障碍的治疗剂和视网膜氧化损伤抑制剂，其包括作为活性成分的化合物。

9. 发明授权

US06333387B1 Ethylene copolymer composition 有权
标题翻译：乙烯共聚物组成
公开(公告)号：US06333387B1
公开(公告)日：2001-12-25
申请号：US09703665
申请日：2000-11-02
申请人： Mamoru Takahashi , Seiichi Ikeyama , Akira Todo , Toshiyuki Tsutsui , Seiji Ohta , Hajime Inagaki
发明人： Mamoru Takahashi , Seiichi Ikeyama , Akira Todo , Toshiyuki Tsutsui , Seiji Ohta , Hajime Inagaki
IPC分类号： C08L2308
CPC分类号： C08L23/0815 , C08F10/02 , C08F110/02 , C08F210/16 , C08F210/18 , C08L23/06 , C08L23/10 , C08L23/12 , C08L23/14 , C08L23/16 , C08L23/20 , C08L23/22 , C08L51/06 , C08L2205/02 , Y10S526/943 , C08F2/00 , C08L2666/24 , C08L2666/06 , C08F2500/12 , C08F2500/11 , C08F2500/08 , C08F210/14 , C08F210/08 , C08F232/00 , C08F2500/25 , C08L2666/04
摘要： Ethylene/&agr;-olefin copolymer with olefin type elastomer, each having particular properties, including density and melt flow rate, with a density ratio of elastomer to copolymer of less than 1, provide compostions which have excellent moldability and form films having high mechanical strength.
摘要翻译：具有烯烃类弹性体的乙烯/α-烯烃共聚物各自具有特定的性能，包括密度和熔体流动速率，弹性体与共聚物的密度比小于1，提供了具有优异成型性和具有高机械强度的成型膜的组合物。

10. 发明申请

US20090306055A1 PHENYLAZOLE COMPOUNDS, PRODUCTION PROCESS AND ANTIOXIDANTS 审中-公开
标题翻译：苯并噻唑化合物，生产工艺和抗氧化剂
公开(公告)号：US20090306055A1
公开(公告)日：2009-12-10
申请号：US12466919
申请日：2009-05-15
申请人： Nobuhiro Umeda , Nobuo Mochizuki , Seiichi Uchida , Mitsumasa Takada , Seiichi Ikeyama , Shiro Tsubokura , Yasuyuki Shiinoki , Fumie Shirato , Hiroko Moroe
发明人： Nobuhiro Umeda , Nobuo Mochizuki , Seiichi Uchida , Mitsumasa Takada , Seiichi Ikeyama , Shiro Tsubokura , Yasuyuki Shiinoki , Fumie Shirato , Hiroko Moroe
IPC分类号： A61K31/496 , C07D405/10 , C07D471/04 , A61K31/453 , A61K31/4525 , A61K31/551 , A61K31/4433 , A61K31/443 , A61K31/4178 , A61K31/4155 , A61K31/437
CPC分类号： C07D471/04 , C07D405/12 , C07D405/14
摘要： The present invention is directed to compounds represented by the formula (1):B-D-Z (1), wherein B represent the following formula (B-1), A represents an optionally substituted imidazole or pyrazole group; E represents the following formula (1a): X represents an oxygen atom, the formula: SOu, or the formula: N—R9; Y represents a carbon atom or a nitrogen atom; D represents an oxygen atom, a sulfur atom or the formula (1a); Z represents (a chroman-2-yl group, a chroman-4-yl group, a 2,3-dihydrobenzofuran-2-yl group, a 2,3-dihydrobenzofuran-3-yl group, etc.) which is substituted with NHR10 or OR11)] or pharmaceutically acceptable salts thereof, and to antioxidants, therapeutic agents for kidney diseases or cerebrovascular disorder, and retinal oxidative damage inhibitors, which include the compounds as the active ingredient.
摘要翻译：本发明涉及由式（1）表示的化合物：B-D-Z（1），其中B表示下式（B-1），A表示任选取代的咪唑或吡唑基; E表示下式（1a）：X表示氧原子，式：SOu或式：N-R 9; Y表示碳原子或氮原子; D表示氧原子，硫原子或式（1a）; Z表示（苯并二氢吡喃-2-基，苯并二氢吡喃-4-基，2,3-二氢苯并呋喃-2-基，2,3-二氢苯并呋喃-3-基等），其被 NHR10或OR11）]或其药学上可接受的盐，以及抗氧化剂，肾脏疾病或脑血管障碍的治疗剂和视网膜氧化损伤抑制剂，其包括作为活性成分的化合物。

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