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1. 发明申请

US20170050185A1 ROTATABLE CARTRIDGE FOR MEASURING A PROPERTY OF A BIOLOGICAL SAMPLE 有权
标题翻译：用于测量生物样品属性的可旋转盒
公开(公告)号：US20170050185A1
公开(公告)日：2017-02-23
申请号：US15343389
申请日：2016-11-04
申请人： Christoph Boehm , Sascha Lutz , Thomas Dolbinow
发明人： Christoph Boehm , Sascha Lutz , Thomas Dolbinow
IPC分类号： B01L3/00 , G01N35/00 , G01N35/10
CPC分类号： B01L3/50273 , B01L3/502715 , B01L3/502738 , B01L2300/041 , B01L2300/044 , B01L2300/0645 , B01L2300/0672 , B01L2300/0803 , B01L2300/0858 , B01L2300/087 , B01L2300/16 , B01L2400/0409 , B01L2400/0683 , G01N35/00069 , G01N35/1079
摘要： A cartridge for an automatic analyzer, formed from a cover and carrier structure, is operable for rotation about an axis and has at least one container with at least one reservoir containing at least one fluid. Each container may rotate about the axis within a cavity and relative to the carrier structure. A piercing structure opens a seal of each reservoir when the container rotates relative to the carrier structure. Each container and each cavity has a frictional element that mate and cause friction. Each container has an engaging surface which mates with an engaging surface of a rotational actuator that applies torque to rotate and open the container via the piercing structure. A fluidic structure of the cartridge processes a biological sample into a processed biological sample and enables via a measurement structure measurement of the processed biological sample. A duct is between the cavity and the fluidic structure.
摘要翻译：用于由盖和载体结构形成的自动分析器的筒可操作以围绕轴线旋转，并且具有至少一个具有至少一个容纳有至少一种流体的容器的容器。每个容器可以在空腔内并且相对于载体结构围绕轴线旋转。当容器相对于承载结构旋转时，穿孔结构打开每个储存器的密封。每个容器和每个空腔都有一个摩擦元件，与之交配并引起摩擦。每个容器具有接合表面，其与旋转致动器的接合表面配合，该转动致动器施加扭矩以经由穿孔结构旋转并打开容器。筒的流体结构将生物样品处理成经处理的生物样品，并且能够经由经处理的生物样品的测量结构测量。管道在空腔和流体结构之间。

2. 发明授权

US10213742B2 Micro flow filtration system and flow filtration method 有权
公开(公告)号：US10213742B2
公开(公告)日：2019-02-26
申请号：US14386097
申请日：2013-03-25
申请人： Norbert Oranth , Nadine Losleben , Sascha Lutz , Adelbert Grossmann
发明人： Norbert Oranth , Nadine Losleben , Sascha Lutz , Adelbert Grossmann
IPC分类号： B01D61/14 , B01D61/18 , B01D61/20 , B01D61/22
摘要： A micro flow filtration system comprises a fluid circuitry (3) and a first reservoir (1) outside the circuitry (3) suitable for containing a fluid. The fluid circuitry (3) comprises a tangential flow filtration module (10) capable of separating the fluid sample into a retentate stream and a permeate stream upon passage of the fluid sample into the tangential flow filtration module (10) through an inlet feed (18). The fluid circuitry (3) further comprises a second reservoir (2) integrated in the fluid circuitry (3), a pump (5) for creating and driving a fluid flow, optionally at least one pressure sensor (6, 7 or 8) for acquiring and detecting data about the fluid sample, optionally a pressure regulator (9) for regulating the flow in the fluid circuitry (3) and a plurality of conduits (22) forming the fluid circuitry (3) together with the second reservoir (2), the TFF-module (10), the pump (5), the pressure sensor (6, 7 or 8) (if present) and the pressure regulator (9) (if present). The volume of the first reservoir (1) outside the circuitry (3) is significantly larger than the volume of the second reservoir (2). The first reservoir (1) outside the fluid circuitry (3) is connected to the circuitry (3) via a connection conduit (31) such that the fluid flows unidirectionally into the circuitry (3) until the first reservoir (1) is empty so that a continuous fluid flow from the first reservoir (1) to the circuitry (3) is established.

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