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1. 发明授权

US09339891B2 Liquid phase laser ablation method and apparatus 有权
标题翻译：液相激光烧蚀方法及装置
公开(公告)号：US09339891B2
公开(公告)日：2016-05-17
申请号：US14000721
申请日：2012-02-13
申请人： Sanshiro Nagare
发明人： Sanshiro Nagare
IPC分类号： B23K26/122 , B82Y40/00 , B23K26/12 , B29C59/16 , B23K26/16 , B23K26/36 , B29C35/08
CPC分类号： B23K26/122 , B23K26/0622 , B23K26/0643 , B23K26/0648 , B23K26/082 , B23K26/1224 , B23K26/16 , B23K26/361 , B23K26/362 , B29C59/16 , B29C2035/0838 , B82Y40/00
摘要： A liquid phase laser ablation apparatus is provided, which includes a vessel for storing liquid in which a component to be atomized is arranged; a laser oscillating device for oscillating a laser light irradiated to the component through the liquid; a reflecting mirror configured to freely change an angle of incidence of the laser light with respect to a surface of the liquid; a focusing lens for focusing the laser light oscillated from the laser oscillating device; a cover body for covering an upper surface of the vessel; and a laser light introduction port provided on the cover body or a side surface of the vessel above the surface of the liquid. Accordingly, liquid will not adhere to optical components constituting the apparatus, there is little contamination and damage to the optical components, and laser ablation can occur in a continuous and stable manner for a long period of time.
摘要翻译：提供了一种液相激光烧蚀装置，其包括用于储存液体的容器，其中布置有被雾化的部件; 激光振荡装置，用于使通过所述液体照射到所述部件的激光振荡; 反射镜，被配置为自由地改变激光相对于液体的表面的入射角; 聚焦透镜，用于聚焦从激光振荡装置振荡的激光; 用于覆盖容器的上表面的盖体; 以及设置在所述盖体上的所述液体的表面上方的所述容器的侧面的激光导入口。因此，液体不会附着在构成装置的光学部件上，对光学部件的污染和损伤小，激光烧蚀可以长时间连续稳定地进行。

2. 发明申请

US20060251584A1 Drug nano-particle, method and apparatus for preparing pharmaceutical preparation using the particle 审中-公开
标题翻译：药物纳米颗粒，使用该颗粒制备药物制剂的方法和装置
公开(公告)号：US20060251584A1
公开(公告)日：2006-11-09
申请号：US10560030
申请日：2004-06-10
申请人： Sanshiro Nagare , Mamoru Senna
发明人： Sanshiro Nagare , Mamoru Senna
IPC分类号： A61K9/14 , A61L9/04
CPC分类号： A61K9/146 , A61K9/14 , A61K9/5123 , A61K9/5192
摘要： This invention provides a drug nanoparticle 7 obtained by irradiating laser beam 3 to a solid target 2 composed of drug powder so as to release the drug as downsized component particle from the solid target 2, wherein the drug nanoparticles 7 has an average diameter of 100 nm or less. According to the above structure, there can be provided: a drug nanoparticle having a high bioavailability, a high purity and an excellent handling property in a case where the drug nanoparticle is used as medical agent, agricultural chemical (agrichemical), chemical fertilizer or the like. The method of manufacturing the drug and the medical agent manufacturing apparatus are capable of effectively manufacturing the drug nanoparticles through simple manufacturing steps.
摘要翻译：本发明提供一种药物纳米粒子7，其通过将激光束3照射到由药物粉末构成的固体靶2上，从固体靶2释放作为小型化成分粒子的药物，其中药物纳米粒子7的平均直径为100nm 或更少。根据上述结构，可以提供：在药物纳米粒子用作药剂的情况下，具有高生物利用度，高纯度和优异的处理性能的药物纳米粒子，农药（农化），化肥或喜欢。制造药物和药剂制造装置的方法能够通过简单的制造步骤有效地制造药物纳米粒子。

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