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1. 发明授权

US12085491B2 Tissue piece treating apparatus 有权
公开(公告)号：US12085491B2
公开(公告)日：2024-09-10
申请号：US17413569
申请日：2019-11-12
申请人： SAKURA SEIKI CO., LTD. , SAKURA FINETEK JAPAN CO., LTD.
发明人： Tetsu Nagabayashi , Takahiro Sakurai
IPC分类号： G01N1/00 , G01N1/31 , G01N1/36
CPC分类号： G01N1/31 , G01N1/36 , G01N2001/315
摘要： A tissue piece treating apparatus including a storage container in which a tissue piece is operable to be housed, and a treating tank in which the storage container is housed, the storage container includes a plurality of through holes, the treating tank is disposed to a main body part by being inclined relative to a horizontal direction, and the storage container is housed by being inclined at the same angle as the treating tank.

2. 发明申请

US20210278428A1 COVER SLIP STICKING DEVICE 有权
公开(公告)号：US20210278428A1
公开(公告)日：2021-09-09
申请号：US16324904
申请日：2017-05-30
申请人： SAKURA SEIKI CO., LTD. , SAKURA FINETEK JAPAN CO., LTD.
发明人： Tomonori KAWAI , Yamato MIYAIRI
IPC分类号： G01N35/00 , G01N1/31 , G02B21/34
摘要： It is an object to provide a cover slip sticking device capable of improving matching between types of clearing agents and cover slips. As a means for solving the problem, a cover slip sticking device includes a dipping bath (21) in which slide glasses (22) on which specimens are attached are housed to be dipped in a clearing agent, a holder (11) having a cover slip (10) and cover slip information (14), a mounting part (C) on which the holder is mounted, a sticking part (B) sticking the cover slip (10) taken out from the holder (11) on the slide glass (22), a reading unit (62) reading the cover slip information (14), a storage unit (65) storing a type of the clearing agent and matching information between types of clearing agents and types of cover slips and a determination unit (66) comparing the cover slip information (14) read by the reading unit (62) and the type of the clearing agent stored in the storage unit (65) with the matching information to determine whether the types match with each other or not.

3. 发明授权

US10267712B2 Centrifugal smearing device and sealed rotating container 有权
公开(公告)号：US10267712B2
公开(公告)日：2019-04-23
申请号：US14778016
申请日：2014-03-07
申请人： Sakura Seiki Co., Ltd. , Sakura Finetek Japan Co., Ltd.
发明人： Matsumi Toya , Tadashi Toufukuji
IPC分类号： G01N1/28 , B01L1/00 , B04B5/10 , B04B7/02 , B04B5/04 , B04B7/06 , B01L3/00 , B01L9/00 , B04B7/08
摘要： A centrifugal smearing device including a sealed rotating container that houses a chamber with a slide glass removably attached for holding a liquid sample to smear cells with a centrifugal force onto the slide glass, and a base housing the sealed rotating container and including rotational driving means for rotating the sealed rotating container, the sealed rotating container includes a main body capable of housing the chamber and a lid for closing an upper surface opening portion of the main body, a seal portion for sealing a space between the main body and the end face of the upper face opening portion is provided on an outer circumferential edge of the lid, and a scattering protection wall is formed at an inside of the seal portion so as to protrude downward to hide the seal portion from inside so that a liquid does not scatter onto the seal portion.

4. 发明授权

US10156502B2 Tissue piece treating method in which liquid chemical is stirred by supplying and draining liquid chemical 有权
公开(公告)号：US10156502B2
公开(公告)日：2018-12-18
申请号：US14900476
申请日：2014-07-01
申请人： Sakura Seiki Co., Ltd. , Sakura Finetek Japan Co., Ltd.
发明人： Atsuo Ito
IPC分类号： G01N1/28 , G01N1/31
摘要： The present invention addresses a problem of providing a tissue piece treating method and a tissue piece treating apparatus by which treatment of a tissue piece by each of liquid chemicals can be favorably performed and a running cost can be reduced. In order to address the problem, in a tissue piece treating method in a tissue piece treating apparatus (30) for executing an immersion treatment process by each of the liquid chemicals by supplying the liquid chemicals with different types into a treatment tank (40) in which a basket (42) accommodating the tissue piece is disposed in a predetermined order, a liquid supply/drain cycle in which the liquid chemical in such an amount that the entire basket (42) is exposed in the treatment tank (40) is drained from the treatment tank (40) during the execution of the immersion treatment process by each of the liquid chemicals, and the drained liquid chemical is supplied into the treatment tank (40) so that the entire basket (42) is immersed is repeatedly performed so as to agitate the liquid chemical.

5. 发明授权

US09829418B2 Centrifugal smearing device and sealed rotating container 有权
公开(公告)号：US09829418B2
公开(公告)日：2017-11-28
申请号：US14778004
申请日：2014-03-07
申请人： Sakura Seiki Co., Ltd. , Sakura Finetek Japan Co., Ltd.
发明人： Matsumi Toya , Tetsu Nagabayashi
IPC分类号： A61B10/00 , G01N1/28 , B04B5/04 , B04B7/02 , B04B7/06 , B01L3/00 , B04B5/10 , B04B7/08
CPC分类号： G01N1/2813 , B01L3/508 , B01L2200/0615 , B01L2200/0689 , B01L2300/042 , B01L2400/0409 , B04B5/0407 , B04B5/10 , B04B7/02 , B04B7/06 , B04B7/08 , B04B2007/025 , G01N2001/2846
摘要： The present invention addresses the problem of providing a centrifugal smearing device and a sealed rotating container in which liquid components do not leak to an outside of the sealed rotating container. To solve this problem, in a centrifugal smearing device (30) including a sealed rotating container (34) that houses a chamber (10) with a slide glass removably attached for holding the liquid sample to smear cells in the liquid sample with a centrifugal force onto the slide glass, and a base (31) housing the sealed rotating container (34) and including rotational driving means (32) for rotating the sealed rotating container (34), the sealed rotating container (34) includes a main body (40) capable of housing the chamber (10) and a lid (42) for closing an upper surface opening portion of the main body (40), and has a storage section (46) for storing liquid scattered from the chamber (10) during being centrifuged, formed on an inside face of the main body (40).

6. 发明申请

US20160153875A1 TISSUE PIECE TREATING METHOD AND TISSUE PIECE TREATING APPARATUS 审中-公开
标题翻译：组织切片治疗方法和组织治疗装置
公开(公告)号：US20160153875A1
公开(公告)日：2016-06-02
申请号：US14900476
申请日：2014-07-01
申请人： SAKURA SEIKI CO., LTD. , SAKURA FINETEK JAPAN CO., LTD.
发明人： Atsuo ITO
IPC分类号： G01N1/31
CPC分类号： G01N1/31 , G01N2001/315
摘要： The present invention addresses a problem of providing a tissue piece treating method and a tissue piece treating apparatus by which treatment of a tissue piece by each of liquid chemicals can be favorably performed and a running cost can be reduced. In order to address the problem, in a tissue piece treating method in a tissue piece treating apparatus (30) for executing an immersion treatment process by each of the liquid chemicals by supplying the liquid chemicals with different types into a treatment tank (40) in which a basket (42) accommodating the tissue piece is disposed in a predetermined order, a liquid supply/drain cycle in which the liquid chemical in such an amount that the entire basket (42) is exposed in the treatment tank (40) is drained from the treatment tank (40) during the execution of the immersion treatment process by each of the liquid chemicals, and the drained liquid chemical is supplied into the treatment tank (40) so that the entire basket (42) is immersed is repeatedly performed so as to agitate the liquid chemical.
摘要翻译：本发明解决了提供一种组织片处理方法和组织片处理装置的问题，通过该组织片处理装置可以有利地进行各种液体化学品的组织片的处理，并且可以降低运行成本。为了解决这个问题，在组织片处理装置（30）中的组织片处理方法中，通过将不同种类的液体化学品供给到处理槽（40）中，对各液体化学品进行浸渍处理，其中容纳组织片的篮子（42）以预定顺序设置，液体供应/排出循环，其中整个篮子（42）暴露在处理槽（40）中的液体化学品排出在每次液体化学品执行浸渍处理过程期间从处理槽（40）中排出的液体化学品被供应到处理槽（40）中，使得整个筐（42）被浸没被重复地执行以搅拌液体化学品。

7. 发明申请

US20160116382A1 TISSUE PIECE TREATING APPARATUS AND METHOD OF OPERATING TISSUE PIECE TREATING APPARATUS 有权
标题翻译：组织治疗装置及组织治疗装置的操作方法
公开(公告)号：US20160116382A1
公开(公告)日：2016-04-28
申请号：US14894952
申请日：2014-05-16
申请人： Sakura Finetek Japan Co., Ltd. , Sakura Seiki Co., Ltd.
发明人： Atsuo ITO
IPC分类号： G01N1/31
CPC分类号： G01N1/31 , G01N1/36
摘要： The present invention addresses the problem of providing a technology capable of automatically preparing a mixed liquid having a fixed ratio. To address the problem, the following processes are carried out in a tissue piece treating apparatus (10). (a) By use of a detection sensor (36), a dehydrating agent is transferred from a dehydrating agent tank (large-capacity tank (15)) to a treatment tank (11) until reaching a prescribed level. (b) By use of the detection sensor (36), an intermediate agent is transferred from an intermediate agent tank (large-capacity tank (17)) to the treatment tank (11) until reaching a prescribed level. (c) An admixture obtained by mixing the dehydrating agent by the process of (a) and the intermediate agent by the process of (b) is transferred from the treatment tank (11) to an admixture tank (14).
摘要翻译：本发明解决了提供能够自动制备具有固定比例的混合液体的技术的问题。为了解决该问题，在组织片处理装置（10）中进行以下处理。（a）通过使用检测传感器（36），将脱水剂从脱水剂槽（大容量罐（15））输送到处理槽（11）直到达到规定的水平。（b）通过使用检测传感器（36），将中间体药剂从中间体罐（大容量罐（17））转移到处理槽（11）直到达到规定的水平。（c）通过（a）的方法将脱水剂与（b）的方法混合使用的混合物从处理槽（11）输送到混合罐（14）。

8. 发明授权

US09164014B2 Thin section fabrication apparatus and method of fabricating thin section 有权
标题翻译：薄截面制造装置及其制造方法
公开(公告)号：US09164014B2
公开(公告)日：2015-10-20
申请号：US14376552
申请日：2013-02-05
申请人： SAKURA FINETEK JAPAN CO., LTD.
发明人： Tetsumasa Ito
IPC分类号： A61B10/00 , G01N1/31 , G01N1/06
CPC分类号： G01N1/31 , G01N1/06 , G01N2001/068
摘要： A thin section fabrication apparatus includes an epi-imaging data acquisition unit that performs imaging by radiating epi-illumination and acquires imaging data, a diffusion imaging data acquisition unit that performs imaging by radiating diffusion illumination and acquires imaging data, an exposed shape extraction unit that extracts an exposed shape of an exposure portion of the biological sample which is exposed to a surface of the embedding block, based on the imaging data acquired by the epi-imaging data acquisition unit, an embedded shape extraction unit that extracts an embedded shape of an embedding portion of the biological sample which is embedded in the embedding block, based on the imaging data acquired by the diffusion imaging data acquisition unit, and a control unit that determines ending of the preliminary cutting by comparing the exposed shape extracted by the exposed shape extraction unit and the embedded shape extracted by the embedded shape extraction unit.
摘要翻译：薄壁制造装置包括：外延成像数据获取单元，其通过辐射外照明并获取成像数据进行成像;漫射成像数据获取单元，其通过辐射扩散照明进行成像并获取成像数据;曝光形状提取单元，基于由外部成像数据获取单元获取的成像数据，提取暴露于嵌入块的表面的生物样品的曝光部分的曝光形状;嵌入形状提取单元，其提取嵌入块的嵌入形状基于由扩散成像数据获取单元获取的成像数据嵌入在嵌入块中的生物样本的嵌入部分，以及控制单元，其通过比较通过曝光形状提取提取的曝光形状来确定预切割的结束单元和嵌入形状提取单元提取的嵌入形状。

9. 发明公开

US20240345112A1 SEALING APPARATUS 审中-公开
公开(公告)号：US20240345112A1
公开(公告)日：2024-10-17
申请号：US18291849
申请日：2022-06-08
申请人： SAKURA SEIKI CO., LTD. , SAKURA FINETEK JAPAN CO., LTD.
发明人： Masahisa Mimura , Hoshinosuke Okada , Kazuki Komiyama , Daiki Hashizume
IPC分类号： G01N35/00 , G01N21/01
CPC分类号： G01N35/00732 , G01N21/01 , G01N2021/0187 , G01N2035/00811
摘要： A sealing apparatus is provided that enables a sealing agent bottle to be replaced with input of an inappropriate sealing agent prevented, and a cover slip, a sealing agent, and a clearing agent appropriately combined. A sealing apparatus (10) includes a starting bath (22) in which a clearing agent is stored and a slide glass (12) on which a specimen before the sealing is attached is dipped in the clearing agent, a sealing agent bottle (44) that stores a sealing agent dispensed onto the slide glass (12) taken out from the starting bath (22), and includes a recording unit (62) in which at least a type of the sealing agent is recorded, a storage unit (68) storing information on compatibility of the clearing agent with respect to a cover slip (26) and the sealing agent currently applied, and a control unit (66) that performs, when the sealing agent bottle (44) is replaced, control of determining the compatibility of the sealing agent read from the recording unit (62) with respect to the cover slip (26) and the clearing agent stored in the storage unit (68), and at least when the result of the determination is incompatible, making a notification unit (20) issue a notification indicating the incompatibility.

10. 发明申请

US20220373438A1 TISSUE PIECE TREATING APPARATUS 有权
公开(公告)号：US20220373438A1
公开(公告)日：2022-11-24
申请号：US17771795
申请日：2020-10-13
申请人： SAKURA SEIKI CO., LTD. , SAKURA FINETEK JAPAN CO., LTD.
发明人： TADASHI TOFUKUJI , MOE OKABE
IPC分类号： G01N1/31 , G01N1/36 , G01N1/44
摘要： The present invention addresses the problem of a tissue piece treating apparatus in which drying in an inside of a treating tank is promoted, compared with conventional tissue piece treating apparatuses, and the gas in the inside of the treating tank is discharged so that a risk of inflammation can be prevented. As a solution, a tissue piece treating apparatus (10) according to the present invention includes: a treating tank (18) in which a tissue piece is housed, and immersion of the tissue piece is performed by a chemical solution being supplied thereto; a communication passage (34) that is connected to the treating tank (18); one or a plurality of chemical solution bottles (24) that are connected to the treating tank (18) through the communication passage (34), and store chemical solutions to be supplied to the treating tank (18); and a pump (60) that causes an inside of the treating tank (18)to be a negative pressure to supply the chemical solution from the chemical solution bottle (24) to the inside of the treating tank (18), and causes the inside of the treating tank (18) to be a positive pressure to discharge the chemical solution from the inside of the treating tank (18) to the chemical solution bottle (24), in which the communication passage (34), which partially branches, includes an outside air port (42) that communicates with an outside air, and is thus configured to be able to supply and discharge the outside air to and from the inside of the treating tank (18) by receiving an action of the pump (60).

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