会员体验
专利管家(专利管理)
工作空间(专利管理)
风险监控(情报监控)
数据分析(专利分析)
侵权分析(诉讼无效)
联系我们
交流群
官方交流:
QQ群: 891211   
微信请扫码    >>>
现在联系顾问~
热词
    • 10. 发明申请
    • METHOD FOR PREFERENTIAL PRODUCTION OF GEOMETRIC ISOMERS AND ISOLATION METHOD
    • 优选生产几何异构体和分离方法的方法
    • WO2007100161A1
    • 2007-09-07
    • PCT/JP2007/054623
    • 2007-03-02
    • NISSAN CHEMICAL INDUSTRIES, LTD.KUSUOKA, YoshiyukiSUZUKI, HideakiTANAKA, Norio
    • KUSUOKA, YoshiyukiSUZUKI, HideakiTANAKA, Norio
    • C07D277/32A01N43/78
    • A01N43/78C07D277/32
    • A method for the preferential production of the Z form of a compound represented by the formula (5) [in the formula (5), Q, A and B have the same meanings as stated below], by reacting an acrylonitrile compound represented by the formula (1) [in the formula (1), Q represents unsubstituted or substituted phenyl or heterocyclyl, in particular 4-thiazolyl, 1- or 3-pyrazolyl, 1,3-oxazolyl-4-yl, phenyl, pyridyl or the like, A represents pyrazolyl, thiazolyl or the like, and B represents alkylcarbonyl or the like] with a compound represented by formula (3) [in the formula (3), B represents alkylcarbonyl or the like] or a compound represented by the formula (4) [in the formula (4), B has the same meaning as aforesaid], in the presence of a compound represented by the formula (2) [in the formula (2) R represents H, dimetylamino and the like], and a method for the isolation of geometric isomers, wherein, by dissolving or suspending a geometric isomer mixture of an acrylonitrile compound represented by the formula (5) in an alcohol or a solvent containing an alcohol, the E form is preferentially decomposed and the Z form is isolated, and wherein the decomposition product can be simply recovered by normal operations and reutilized.
    • 优选制备由式(5)[式(5)中Q,A和B表示的化合物的Z形式的Z形式的方法具有如下所述的相同含义],通过使由 式(1)[式(1)中,Q表示未取代或取代的苯基或杂环基,特别是4-噻唑基,1-或3-吡唑基,1,3-恶唑基-4-基,苯基,吡啶基等 与式(3)表示的化合物[式(3)中,B表示烷基羰基等]或式(I)表示的化合物,A表示吡唑基,噻唑基等,B表示烷基羰基等] 4)[式(4)中,B具有与上述相同的含义],在式(2)表示的化合物[式(2)中R表示H,二甲基氨基等]的存在下, 分离几何异构体的方法,其中通过溶解或悬浮丙烯腈化合物代表的几何异构体混合物 通过式(5)在醇或含有醇的溶剂中,E型优先分解,Z形分离,其中分解产物可以通过正常操作简单回收并重新利用。