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1. 发明申请

WO2021130532A1 PROCESS FOR PRODUCING A PHARMACEUTICAL COMPOSITION CONTAINING MICRO PARTICLES 审中-公开
公开(公告)号：WO2021130532A1
公开(公告)日：2021-07-01
申请号：PCT/IB2020/001034
申请日：2020-12-18
申请人： SUNSTAR INC.
发明人： ARAKI, Mayo , TANAKA, Rie , TAKEDA, Youko
IPC分类号： A61K9/06 , A61K31/65 , A61K47/02 , A61K47/10 , A61K47/14 , A61K47/32 , A61K47/36 , A61K47/38 , A61K9/1611 , A61K9/1617 , A61K9/1635 , A61K9/1652 , A61K9/1682
摘要： A pharmaceutical composition having consistently a desirable release rate is prepared by controlling the finally mixing time based on the molecular weight measured in the intermediate product. The pharmaceutical composition includes micro particles containing a polyhydric alcohol, a salt, a water-soluble polymer and a pharmaceutically active ingredient. The micro particles are dispersed in a matrix of a hydrophobic ingredient and an amphipathic ingredient.

2. 发明申请

WO2009036204A3 PHASE II DETOXIFICATION AND ANTIOXIDANT ACTIVITY 审中-公开
公开(公告)号：WO2009036204A3
公开(公告)日：2009-03-19
申请号：PCT/US2008/076064
申请日：2008-09-11
申请人： JOSLIN DIABETES CENTER, INC. , SUNSTAR INC. , BLACKWELL, T. Keith , MATSUMOTO, Motonobu , MAKINO, Taketoshi , GOTO, Masashi , ISHIKADO, Atsushi , MAEDA, Mariko , AZECHI, Satoe
发明人： BLACKWELL, T. Keith , MATSUMOTO, Motonobu , MAKINO, Taketoshi , GOTO, Masashi , ISHIKADO, Atsushi , MAEDA, Mariko , AZECHI, Satoe
IPC分类号： A61K47/00
摘要： Provided are methods and compositions that enhance Nrf2 (SKN-1) activation of phase II detoxification or antioxidant enzyme transcription, comprising plant extracts (e.g., willow extracts) or active fractions thereof, as well as methods for identifying additional compounds that increase the Nrf2-regulation of those enzymes.

3. 发明申请

WO1998017236A1 ORAL PREPARATIONS CONTAINING BIOLOGICALLY ACTIVE CRYSTALLIZED GLASS 审中-公开
标题翻译：含有生物活性结晶玻璃的口腔制剂
公开(公告)号：WO1998017236A1
公开(公告)日：1998-04-30
申请号：PCT/JP1997003843
申请日：1997-10-23
申请人： SUNSTAR INC. , INOUE, Tamae , OSAKA, Akiyoshi
发明人： SUNSTAR INC.
IPC分类号： A61K07/16
CPC分类号： A61K6/0017 , A61K6/0067 , A61K6/0091
摘要： An oral preparation characterized by containing a biologically active crystallized glass comprising 25 to 60 wt.% of SiO2, 15 to 60 wt.% of CaO and 0 to 30 wt.% of P2O5, with each percentage being based on the crystallized glass; an oral paint prepared by further adding a film-forming substance and an organic solvent to the preparation; and another oral preparation prepared by further adding a polymer capable of adhering to the surface of a tooth to the above preparation.
摘要翻译：一种口服制剂，其特征在于含有25-60重量％的SiO2，15-60重量％的CaO和0-30重量％的P2O5的生物活性结晶玻璃，其中每个百分数均以结晶玻璃为基准; 通过向制剂中进一步添加成膜物质和有机溶剂而制备的口腔涂料; 以及通过进一步添加能够粘附到牙齿表面上的聚合物制备的另一种口服制剂。

4. 发明申请

WO1997046137A1 TOOTH BRUSH 审中-公开
标题翻译：牙刷
公开(公告)号：WO1997046137A1
公开(公告)日：1997-12-11
申请号：PCT/JP1997001966
申请日：1997-06-05
申请人： SUNSTAR INC. , MORI, Toyokazu , SAKURAI, Shinya , MATSUMOTO, Hitoshi , NISHIMURA, Koki , KUBO, Koichi
发明人： SUNSTAR INC.
IPC分类号： A46D01/04
CPC分类号： A46D1/023 , A46B2200/1066 , A46D1/00 , A46D1/0276 , A46D1/0284 , A46D1/0292 , A46D1/04
摘要： A tooth brush having an excellent cleaning effect to detail portions inside an oval cavity to which bacterial plaque easily adheres, such as interdental portions, dental neck portions, pits and fissures, etc., and from which removal of the plaque so deposited by a tooth brush has been regarded as difficult. The tooth brush has a soft impact to the gingiva, does not damage the gingiva nor imparts a pain, is highly stiff and has an excellent plaque removal effect. Sea-and-island type composite fibers, in which two to five islands of polyamide resin are dispersed in a sea portion of a polyester resin, are implanted to an implantation bed, the sea-and-island type composite fiber so implanted has a composite portion comprising the island portions and the sea portions over a predetermined length from the proximal end portion of implantation, and only the island portions are disposed on the distal end side from this composite portion in such a manner as to form two to five core hairs of predetermined length.
摘要翻译：一种具有优良清洁效果的牙刷，用于细细细菌斑块容易粘附的椭圆形腔内的部分，例如齿间部分，牙颈部分，凹坑和裂缝等，并且由牙齿去除由牙齿沉积的斑块刷被认为是困难的。牙刷对牙龈具有柔软的冲击，不会损伤牙龈，也不会产生疼痛，硬度高，具有优异的牙斑清除效果。其中将聚酰胺树脂的2至5个岛分散在聚酯树脂的海水部分中的海岛型复合纤维被植入植入床，所以植入的海岛型复合纤维具有复合材料包括从植入的基端部开始的规定长度的岛部和海部的部分，并且只有岛部从该复合部分配置在远端侧，从而形成两至五根核心毛预定长度。

5. 发明申请

WO1997034710A1 VIBRATION GENERATING DEVICE AND ORAL HYGIENE DEVICE USING SAME 审中-公开
标题翻译：使用相同的振动发生装置和口腔卫生装置
公开(公告)号：WO1997034710A1
公开(公告)日：1997-09-25
申请号：PCT/JP1997000959
申请日：1997-03-21
申请人： SUNSTAR INC. , MATSUI, Tsuguo , SUGIMOTO, Michihisa , KITA, Masaharu
发明人： SUNSTAR INC.
IPC分类号： B06B01/04
CPC分类号： A61C17/3481 , A61C17/224 , A61C17/3427 , B06B1/045 , H02K49/10 , Y10T74/18552
摘要： An oral hygiene device comprises a rotating body (22) mounted to a rotating shaft (21) of an electric motor (14), an output shaft (11) resiliently supported via a resonance pin (25) to be swingable finely, a drive magnetic body (23) provided on the rotating body (22), and a driven magnetic body (31) provided on the output shaft (11) to face the drive magnetic body (23) so as to be out of contact therewith. The drive magnetic body (23) and the driven magnetic body (31) are composed of permanent magnets, and as the rotating body (22) revolves, a varying magnetic field is generated between the both magnetic bodies (23, 31) to cause vibration of the output shaft (11) at high speed. In this manner, there are provided a vibration generating device, which can be manufactured at low cost and efficiently transmit vibration, and an oral hygiene device using the same.
摘要翻译：一种口腔清洁装置，包括安装在电动机（14）的旋转轴（21）上的旋转体（22），经由共振销（25）弹性支撑以便可微调的输出轴（11），驱动磁设置在旋转体（22）上的主体（23）和设置在输出轴（11）上以与驱动磁体（23）相对的驱动磁体（31），以与其不接触。驱动磁体（23）和被驱动磁体（31）由永磁体构成，随着旋转体（22）旋转，在两个磁体（23,31）之间产生变化的磁场，引起振动的输出轴（11）。以这种方式，提供了可以以低成本制造并且有效地传递振动的振动产生装置，以及使用该振动产生装置的口腔卫生装置。

6. 发明申请

WO2009036204A2 PHASE II DETOXIFICATION AND ANTIOXIDANT ACTIVITY 审中-公开
标题翻译： II期脱毒和抗氧化活性
公开(公告)号：WO2009036204A2
公开(公告)日：2009-03-19
申请号：PCT/US2008076064
申请日：2008-09-11
申请人： JOSLIN DIABETES CENTER INC , SUNSTAR INC , BLACKWELL T KEITH , MATSUMOTO MOTONOBU , MAKINO TAKETOSHI , GOTO MASASHI , ISHIKADO ATSUSHI , MAEDA MARIKO , AZECHI SATOE
发明人： BLACKWELL T KEITH , MATSUMOTO MOTONOBU , MAKINO TAKETOSHI , GOTO MASASHI , ISHIKADO ATSUSHI , MAEDA MARIKO , AZECHI SATOE
IPC分类号： F03D1/04
CPC分类号： A61K36/76 , G01N33/5014 , G01N2500/10
摘要： Provided are methods and compositions that enhance Nrf2 (SKN-1) activation of phase II detoxification or antioxidant enzyme transcription, comprising plant extracts (e.g., willow extracts) or active fractions thereof, as well as methods for identifying additional compounds that increase the Nrf2-regulation of those enzymes.
摘要翻译：提供了增强Nrf2（SKN-1）激活II期解毒或抗氧化酶转录的方法和组合物，其包含植物提取物（例如柳树提取物）或其活性部分，以及鉴定增加Nrf2- 这些酶的调节。

7. 发明申请

WO1994024990A1 INTRAORAL COMPOSITION 审中-公开
标题翻译：内在成分
公开(公告)号：WO1994024990A1
公开(公告)日：1994-11-10
申请号：PCT/JP1994000690
申请日：1994-04-25
申请人： SUNSTAR INC. , OTSUKI, Hidehiko , NISHIMURA, Naoko , TSUMURA, Yukako
发明人： SUNSTAR INC.
IPC分类号： A61K07/16
CPC分类号： A61Q11/00 , A61K8/34 , A61K8/375 , A61K8/90 , A61K47/10 , A61K47/14
摘要： An intraoral composition containing at least one arylpropionate nonsteroidal antiphlogistic, which is improved in oral mucosa penetration and reduced in oral irritation by incorporating at least one of polyethylene glycol and isoprene glycol or 1-30 wt.%, based on the whole composition, of hexylene glycol. An intraoral composition that can exhibit an excellent effect of treating and preventing periodontal diseases such as gingivitis or periodontitis for long and that can incorporate stably the arylpropionate nonsteroidal antiphlogistic even after the lapse of time even when filled in a container lined with a synthetic resin is provided either by incorporating the arylpropionate nonsteroidal antiphlogistic in the presence of both a polyoxyethylene-polyoxypropylene copolymer surfactant and L-menthol or in the presence of both a nonionic surfactant and at least one member selected from the group consisting of fatty acid esters of propylene glycol, glycerol and higher alcohols, or by incorporating 0.01-20 parts by weight of at least one member selected from the group consisting of terpene hydrocarbons, phenolic compounds and derivatives thereof, and halogenated diphenyl ethers per part by weight of the arylpropionate nonsteroidal antiphlogistic.
摘要翻译：含有至少一种芳基丙酸酯非甾类消炎药的口腔内组合物，其通过加入聚乙二醇和异戊二醇中的至少一种或基于整个组合物为1-30重量％的口服粘膜渗透而降低口服刺激性，乙二醇。可以显示出治疗和预防诸如牙龈炎或牙周炎等牙周病的良好效果的口腔内组合物，即使在填充在内衬有合成树脂的容器的情况下，即使经过时间也能稳定地并入芳基丙酸酯非甾体类消炎药在聚氧乙烯 - 聚氧丙烯共聚物表面活性剂和L-薄荷醇存在下，或者在非离子表面活性剂和选自丙二醇的脂肪酸酯，甘油的至少一种的存在下，通过加入芳基丙酸酯非甾类消炎药或高分子量醇，或者通过掺入0.01-20重量份的选自萜烯烃，酚类化合物及其衍生物和卤代二苯醚中的至少一种，每重量份芳基丙酸酯非甾类消炎药。

8. 发明申请

US20230021605A1 CHEWING ASSISTANCE SYSTEM 有权
公开(公告)号：US20230021605A1
公开(公告)日：2023-01-26
申请号：US17788636
申请日：2020-12-22
申请人： SUNSTAR INC.
发明人： Takeshi KANATA
IPC分类号： A61B5/397 , A61B5/11 , A61B5/22 , A61B5/00
摘要： Provided are chewing information storage means that stores information about chewing quality, muscle activity obtaining means that obtains a muscle activity signal of masticatory muscle of a person, analysis means that frequency-analyzes the muscle activity signal obtained by the muscle activity obtaining means, and analyzes chewing behavior based on the frequency-analyzed muscle activity signal, quality determination means determines quality of the chewing behavior based on information of the chewing behavior analyzed by the analysis means, and extraction means that extracts assistance information corresponding to the chewing quality determined by the quality determination means, from chewing information storage means.

9. 发明授权

US11478342B2 Electric toothbrush 有权
公开(公告)号：US11478342B2
公开(公告)日：2022-10-25
申请号：US16607078
申请日：2018-04-24
申请人： SUNSTAR INC.
发明人： Yukinori Wada
IPC分类号： A61C17/34 , A61C17/22
摘要： A brush head is provided on the front surface at a distal-end-side part of a neck of a replaceable brush. A fitting shaft portion is provided on a planting base of the brush head so as to protrude rearward and penetrate through a support wall portion of the neck. A shaft hole is formed at a rotation center of a brush head body of the brush head so as to extend frontward from a rear surface of the brush head body. The neck has ahead support shaft mounted to the shaft hole so as to rotatably support the brush head. A front end of the head support shaft is located frontward of a rear surface of the planting base, and power from the driving portion is transmitted to a rear part of the fitting shaft portion.

10. 发明申请

US20200170766A1 DENTAL FLOSS 审中-公开
公开(公告)号：US20200170766A1
公开(公告)日：2020-06-04
申请号：US16702050
申请日：2019-12-03
申请人： SUNSTAR INC. , Nishinokaze Gizyutsu Kobo, LLC
发明人： Atsushi KINUGASA , Kousuke TORII , Kunio NISHIMOTO
IPC分类号： A61C15/04
摘要： A dental floss 2 containing a multifilament is a flat braided cord. The number of threads constituting the flat braided cord is preferably 6 to 33, and the dental floss preferably has a width of 0.5 to 4.0 mm, and a passage gap of 0.01 to 0.1 mm. The flat cord may contain a monofilament or a multifilament-connected thread together with the multifilament. Constituent threads of the braided cord are obliquely arranged and fixed, and, when the cord is moved in a length direction, the obliquely fixed constituent threads efficiently remove food residue, dental plaque, and the like between teeth. Furthermore, the flat braided cord is flat and thin, and easy to insert between teeth. Accordingly, a dental floss that can efficiently remove food residue, dental plaque, and the like between teeth is provided.

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