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1. 发明申请

WO2009104168A3 ANTIPATHOGENIC BIOMEDICAL IMPLANTS, METHODS AND KITS EMPLOYING PHOTOCATALYTICALLY ACTIVE MATERIAL 审中-公开
标题翻译：抗生素生物医学植入物，使用光化学活性材料的方法和工具
公开(公告)号：WO2009104168A3
公开(公告)日：2010-06-10
申请号：PCT/IB2009050715
申请日：2009-02-20
申请人： STROEMME MARIA , WELCH KEN , ENGQVIST HAAKAN
发明人： STROEMME MARIA , WELCH KEN , ENGQVIST HAAKAN
IPC分类号： A61L27/42 , A61L27/44 , A61L27/54
CPC分类号： A61L27/54 , A61L2300/102 , A61L2300/404 , A61L2300/624 , A61L2300/63
摘要： An antipathogenic biomedical implant is formed throughout its structure of a matrix material comprising at least about 1 weight percent of a photocatalytically active filler which exhibits an antipathogenic effect upon irradiation with light. The photocatalytically active filler is arranged in the matrix material in the implant to receive light irradiated from an external light source. In another embodiment, an antipathogenic biomedical implant comprises at least about 1 weight percent of a photocatalytically active material which exhibits an antipathogenic effect upon irradiation with light, wherein the photocatalytically active material is arranged in the implant to receive light irradiated from an external light source. Methods for providing an antipathogenic biomedical implant, methods for reducing pathogens on a biomedical implant, methods for reducing the bioburden in a biomedical implant installation, and kits for providing an antipathogenic biomedical implant employ the antipathogenic biomedical implants.
摘要翻译：在其基质材料的整个结构中形成抗病原生物医学植入物，其包含至少约1重量％的光催化活性填料，其在用光照射时表现出抗病原作用。将光催化活性填料布置在植入物中的基质材料中以接收从外部光源照射的光。在另一个实施方案中，抗病原生物医学植入物包含至少约1重量％的光催化活性材料，其在照射光时表现出抗病原作用，其中所述光催化活性材料布置在植入物中以接收从外部光源照射的光。用于提供抗病原生物医学植入物的方法，用于减少生物医学植入物上的病原体的方法，用于减少生物医学植入物装置中的生物负载的方法以及用于提供抗病原性生物医学植入物的试剂盒使用抗病原生物医学植入物。

2. 发明申请

WO2009098658A3 CRYSTALLINE SURGICAL IMPLANT COMPOSITE MATERIALS AND KITS AND METHODS OF MANUFACTURE 审中-公开
标题翻译：晶体植入物复合材料及其制造方法及制造方法
公开(公告)号：WO2009098658A3
公开(公告)日：2010-07-29
申请号：PCT/IB2009050483
申请日：2009-02-05
申请人： SANDVIK INTELLECTUAL PROPERTY , STROEMME MARIA , ENGQVIST HAAKAN
发明人： STROEMME MARIA , ENGQVIST HAAKAN
IPC分类号： A61L27/30 , A61L27/56
CPC分类号： A61L27/306 , A61L27/56 , A61L2420/02 , A61L2420/08 , A61L2430/02
摘要： A meit-extruded substrate (e.g., fiim, nonwoven web, etc.) that contains a thermoplastic starch formed from a starch and plasticizer is provided. The starch and plasticizer are melt blended together in the presence of a weak organic acid (e.g., lactic acid, formic acid, acetic acid, etc.). By selectively controlling certain parameters of the melt blending process (e.g., extrusion temperature, content of the components, etc.), the present inventors have discovered that the starch may be hydrolyzed in a highly efficient manner to form compositions having a comparably lower weight average molecular weight, polydispersity index, and viscosity, which are particularly suitable for use in the formation of melt-extruded substrates.
摘要翻译：提供了包含由淀粉和增塑剂形成的热塑性淀粉的经过挤出的基材（例如，薄膜，非织造纤维网等）。淀粉和增塑剂在弱有机酸（如乳酸，甲酸，乙酸等）存在下熔融共混。通过选择性地控制熔融共混过程的某些参数（例如，挤出温度，组分含量等），本发明人已经发现淀粉可以以高效的方式水解以形成具有相对较低重量平均值的组合物分子量，多分散性指数和粘度，其特别适用于形成熔融挤出的基材。

3. 发明申请

WO2009069086A2 COMPOSITE MATERIALS INCLUDING AN INTRINSICALLY CONDUCTING POLYMER, AND METHODS AND DEVICES 审中-公开
标题翻译：包含本体导电聚合物的复合材料，以及方法和装置
公开(公告)号：WO2009069086A2
公开(公告)日：2009-06-04
申请号：PCT/IB2008054967
申请日：2008-11-26
申请人： STROEMME MARIA , NYHOLM LEIF , MIHRANYAN ALBERT
发明人： STROEMME MARIA , NYHOLM LEIF , MIHRANYAN ALBERT
CPC分类号： H01B1/127 , C08G2261/3221 , C08G2261/94 , C08J7/047 , D06M15/61 , H01G9/155 , H01G11/56 , H01M4/045 , H01M4/13 , H01M4/137 , H01M4/139 , H01M4/1399 , H01M4/661 , H01M4/667 , H01M10/0525 , H01M2004/021 , Y02E60/122 , Y02E60/13 , Y02P70/54 , Y10T428/1331
摘要： A composite material in the form of a continuous structure comprises an intrinsically conducting polymer (ICP) layer coated on a substrate, the composite material having a surface area of at least 0.1 m2/g, at least 1 m2/g, or at least 5 m2/g. Methods of manufacturing the composite material comprise coating the substrate with a layer of the intrinsically conducting polymer. Electrochemical or electrical devices comprise at least one component formed of the composite material.
摘要翻译：连续结构形式的复合材料包括涂覆在基材上的固有导电聚合物（ICP）层，复合材料的表面积至少为0.1m 2 / g，至少1m 2 / g，或至少5 米2 /克。制造复合材料的方法包括用本体导电聚合物层涂覆基底。电化学或电气装置包括由复合材料形成的至少一个部件。

4. 发明申请

WO2009037659A3 MAGNETIC DETECTION OF SMALL ENTITIES 审中-公开
标题翻译：小型实体的磁性检测
公开(公告)号：WO2009037659A3
公开(公告)日：2009-05-28
申请号：PCT/IB2008053789
申请日：2008-09-17
申请人： STROEMBERG MATTIAS , GOERANSSON JENNY , GUNNARSSON KLAS , NILSSON MATS , SVEDLINDH PETER , STROEMME MARIA
发明人： STROEMBERG MATTIAS , GOERANSSON JENNY , GUNNARSSON KLAS , NILSSON MATS , SVEDLINDH PETER , STROEMME MARIA
IPC分类号： C12Q1/68
CPC分类号： G01N33/542 , C12Q1/6825 , C12Q1/6844 , C12Q1/6851 , G01N2458/10 , C12Q2563/155 , C12Q2563/143 , C12Q2531/125 , C12Q2545/114
摘要： The present invention relates to a novel detection or quantifying method for biological entities or molecules such as, but not limited to, DNA, microorganisms and pathogens, proteins and antibodies, that by themselves are target molecules or from which target molecules are extracted. The methods comprise the steps of i) forming target molecule-dependent volume- amplified entities, ii) allowing magnetic nanoparticles to bind to said volume-amplified entities, and iii) measuring changes in dynamic magnetic response of the magnetic nanoparticles caused by the increase in hydrodynamic volume of said magnetic nanoparticles or measuring the magnetic field due to the magnetic nanoparticles as they bind to a sensor surface functionalized with a secondary capturing probe. The present invention further relates to biosensors and kits to be used in such a method.
摘要翻译：本发明涉及用于生物实体或分子（例如但不限于DNA，微生物和病原体，蛋白质和抗体）的新型检测或定量方法，其自身是靶分子或从中提取靶分子。所述方法包括以下步骤：i）形成靶分子依赖性体积放大实体，ii）允许磁性纳米颗粒结合所述体积放大实体，以及iii）测量由于所述磁性纳米颗粒的增加而引起的所述磁性纳米颗粒的动态磁响应的变化所述磁性纳米颗粒的流体动力学体积或测量当磁性纳米颗粒结合用二级捕获探针功能化的传感器表面时的磁场。本发明进一步涉及用于这种方法的生物传感器和试剂盒。

5. 发明专利

EA018466B1 КРИОГЕЛИ ИЗ СОПОЛИМЕРА ВИНИЛОВОГО СПИРТА, СОПОЛИМЕРЫ ВИНИЛОВОГО СПИРТА И СПОСОБЫ ИХ ПОЛУЧЕНИЯ И ПРОДУКТЫ ИЗ НИХ 未知
公开(公告)号：EA018466B1
公开(公告)日：2013-08-30
申请号：EA201100494
申请日：2009-09-14
申请人： STROEMME MARIA , MIHRANYAN ALBERT
发明人： STROEMME MARIA , MIHRANYAN ALBERT
IPC分类号： C08F8/12 , A61K9/00 , C08F218/08
摘要： Визобретенииобразующийкриогельсополимервиниловогоспиртапозволяетприпроведенииоперацийс нимполучатькриогель, тоестьгидрогель, полученныйв результатекриотропногогелеобразования, вводномраствореприконцентрациименьшечемприблизительно 10 мас.%, вотсутствиехимическогосшивающегоагентаи вотсутствиеэмульгатора. Криогельизсополимеравиниловогоспиртасодержитпоменьшеймереприблизительно 75 мас.% водыи сополимервиниловогоспирта, включающийомыленныйпродуктсополимеравинилацетата, полученногопоменьшеймереизприблизительно 80 мас.% мономеравинилацетатаи (i) поменьшеймереприблизительно 3 мас.% мономераакриламидаилисмесимономераакриламидаи мономераакриловойкислотыили (ii) поменьшеймереприблизительно 5 мас.% мономераакриловойкислоты. Сополимервинилацетата, сополимервиниловогоспиртаи криогельизсополимеравиниловогоспиртамогутбытьполученыв соответствиис конкретнымиспособами, акриогелиизсополимероввиниловогоспиртамогутбытьиспользованыв различныхобластяхприменения, включающихбиомедицинскиеимплантатыи тонкиепленки, идлядоставкитерапевтическихиликосметическихагентов.

6. 发明专利

CA2736833A1 VINYL ALCOHOL CO-POLYMER CRYOGELS, VINYL ALCOHOL CO-POLYMERS, AND METHODS AND PRODUCTS THEREOF 未知
公开(公告)号：CA2736833A1
公开(公告)日：2010-03-18
申请号：CA2736833
申请日：2009-09-14
申请人： STROEMME MARIA , MIHRANYAN ALBERT
发明人： STROMME MARIA , MIHRANYAN ALBERT
IPC分类号： C08F8/12 , A61K9/00 , C08F218/08
摘要： A cryogel-forming vinyl alcohol co-polymer is operable to form a cryogel, i.e., a hydrogel formed by crytropic gelation, in an aqueous solution at a concentration of less than about 10% by weight, in the absence of a chemical cross-linking agent and in the absence of an emulsifier. In one embodiment, a vinyl alcohol co-polymer cryogel comprises at least about 75% by weight water and a vinyl alcohol co-polymer, wherein the vinyl alcohol co-polymer is operable to form a cryogel in an aqueous solution at a concentration of less than about 10% by weight, in the absence of a chemical cross-linking agent and in the absence of an emulsifier. In another embodiment, a vinyl alcohol co-polymer cryogel comprises at least abut 75% by weight water and a vinyl alcohol co-polymer comprising a saponified product of a vinyl acetate co- polymer formed from at least about 80% by weight of vinyl acetate monomer, and (i) at least about 3% by weight of acrylamide monomer or a mixture of acrylamide monomer and acrylic acid monomer, or (ii) at least about 5% by weight acrylic acid monomer. The vinyl acetate co- polymer, vinyl alcohol co-polymer and vinyl alcohol co-polymer cryogel may be formed according to particular methods, and the vinyl alcohol co-polymer cryogels may be used in various applications including biomedical implants and thin films and for delivery of therapeutic or cosmetic agents.

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