专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明专利

JP2005121661A Hematology controls and system for multi-parameter blood measurement 审中-公开
标题翻译：用于多参数血液测量的血液学控制和系统
公开(公告)号：JP2005121661A
公开(公告)日：2005-05-12
申请号：JP2004302032
申请日：2004-10-15
申请人： Streck Lab Inc , ストレックラボラトリーズ,インコーポレーテッドStreck Laboratories,Inc.
发明人： RYAN WAYNE L , SCHOLL JOHN
IPC分类号： G01N1/28 , G01N15/10 , G01N33/49 , G01N33/50 , G01N33/543 , G01N33/96
CPC分类号： G01N33/5094 , G01N33/96 , G01N2001/2893 , G01N2015/1018 , Y10S436/807 , Y10T436/10 , Y10T436/101666 , Y10T436/105831 , Y10T436/106664 , Y10T436/107497 , Y10T436/108331 , Y10T436/2525
摘要： PROBLEM TO BE SOLVED: To provide a hematology control composition and a system used for measuring a plurality of parameters in a blood sample with a multi-parameter automatic apparatus for blood. SOLUTION: The system for measuring blood components includes a control to be used for (a) an automatic test apparatus and (b) a test apparatus. The control comprises (1) an isotonic suspension medium obtained of leukocyte subpopulations and including an agent for assuring a properly positioned five-part scattergram; (2) a component selected from the group of a reticulocyte component, a leukocyte component, an erythrocyte component, a nucleated erythrocyte component, a platelet component, a reticulated platelet component, and a mixture thereof; and (3) a reticulocyte component. COPYRIGHT: (C)2005,JPO&NCIPI
摘要翻译：要解决的问题：提供一种血液控制组合物和用于使用用于血液的多参数自动装置测量血液样品中的多个参数的系统。解决方案：用于测量血液成分的系统包括用于（a）自动测试装置和（b）测试装置的控制。对照包括（1）白细胞亚群获得的等渗悬浮介质，并包括用于确保适当定位的五部分散点图的试剂; （2）选自网织红细胞成分，白细胞成分，红细胞成分，成核红细胞成分，血小板成分，网状血小板成分及其混合物的成分; 和（3）网织红细胞成分。版权所有（C）2005，JPO＆NCIPI

2. 发明申请

WO1992019951A1 TISSUE FIXATIVE AND METHOD 审中-公开
标题翻译：组织固定和方法
公开(公告)号：WO1992019951A1
公开(公告)日：1992-11-12
申请号：PCT/US1992003758
申请日：1992-05-08
申请人： STRECK LABORATORIES, INC.
发明人： STRECK LABORATORIES, INC. , RYAN, Wayne, L.
IPC分类号： G01N01/30
CPC分类号： G01N1/30 , G01N2001/307 , Y10S435/96
摘要： Tissue fixatives, such as diazolidinyl urea, which are free of aldehydes and toxic chemicals are described. When used, either in aqueous or alcoholic solutions, good tissue preservation is attained. In addition, tissue antigens are retained which makes the fixative useful for immunostaining procedures.
摘要翻译：描述了不含醛和有毒化学物质的组织固定剂，如二唑烷基脲。当用于水溶液或醇溶液时，可获得良好的组织保存。此外，保留了组织抗原，这使得固定剂可用于免疫染色程序。

3. 发明专利

AU3717197A Method and composition for preserving antigens and nucleic acids and process for utilizing cytological material produced by same 未知
公开(公告)号：AU3717197A
公开(公告)日：1998-02-09
申请号：AU3717197
申请日：1997-07-16
申请人： STRECK LABORATORIES INC
发明人： RYAN WAYNE L
IPC分类号： A61K39/00 , A61K39/21 , G01N1/30 , G01N33/567 , G01N33/50 , C12Q1/08 , G01N31/00

4. 发明专利

DK1816461T3 Fremgangsmåde og indretning til indsamling og sikring af celler til brug for analyse 未知
公开(公告)号：DK1816461T3
公开(公告)日：2020-04-14
申请号：DK07008752
申请日：2003-10-16
申请人： STRECK LABORATORIES INC
发明人： RYAN WAYNE L
IPC分类号： G01N1/31 , A01N1/00 , B01L3/14 , B01L99/00

5. 发明专利

AU6645900A Hematology control and system for multi-parameter hematology measurements 未知
公开(公告)号：AU6645900A
公开(公告)日：2001-03-19
申请号：AU6645900
申请日：2000-08-17
申请人： STRECK LABORATORIES INC
发明人： RYAN WAYNE L , SCHOLL JOHN
IPC分类号： G01N1/28 , G01N15/10 , G01N33/49 , G01N33/50 , G01N33/543 , G01N33/96 , G01N31/00
摘要： Hematology control compositions and systems used to measure a plurality of parameters in a blood sample are provided. The hematology control compositions are particularly useful as a control for multi-parameter, automated instrument systems. The control compositions comprise a reticulocyte component, a white blood cell component, a red blood cell component, a nucleated red blood cell component, a platelet component and a reticulated platelet component. Methods of making and using the control compositions are also provided.

6. 发明专利

AU4341700A Blood control and system for erythrocyte sedimentation measurement 未知
公开(公告)号：AU4341700A
公开(公告)日：2000-11-17
申请号：AU4341700
申请日：2000-04-12
申请人： STRECK LABORATORIES INC
发明人： RYAN WAYNE L
IPC分类号： G01N33/96
摘要： A control and system for blood testing, including a control having morphologically fixed and stabilized blood cells that have been added to a diluent. The control and system can be used advantageously for indirect acute protein plasma measurement, including erythrocyte sedimentation rate testing.

7. 发明申请

WO2006110339A1 CELLULAR STANDARDS FOR GLYCATED HEMOGLOBIN AlC DETERMINATION 审中-公开
标题翻译：用于糖化HEMOGLOBIN AlC测定的细胞标准品
公开(公告)号：WO2006110339A1
公开(公告)日：2006-10-19
申请号：PCT/US2006/011884
申请日：2006-03-30
申请人： STRECK LABORATORIES, INC. , RYAN, Wayne , WU, Jiong
发明人： RYAN, Wayne , WU, Jiong
IPC分类号： G01N33/72 , C07K14/805
CPC分类号： G01N33/723 , Y10T436/10 , Y10T436/105831 , Y10T436/108331 , Y10T436/25 , Y10T436/25125
摘要： Disclosed are cellular hemoglobin AIc (Hb AIc ) normal and abnormal (high) controls for use in detecting Hb AIc levels. The present invention also relates to methods for generating cellular Hb AIc controls using red blood cells and methods for using the cellular controls. The present invention encompasses several methods for the preparation of Hb AIc cellular controls including: (1) a boronate method where the glycation occurs non-specif ically; (2) a stabilized diabetic blood method where the glycation occurs specifically on Hb AIc, and (3) the glycation of normal blood method that is achieved by controlling conditions such that glycation occurs predominantly on Hb AIc. These methods produce cellular Hb AIc controls with desirable stability and that can be detected on a variety of instruments. In preferred embodiments, the control contains intact erythrocytes .
摘要翻译：公开了用于检测Hb AIc水平的细胞血红蛋白AIc（Hb AIc）正常和异常（高）对照。本发明还涉及使用红细胞产生细胞Hb AIc对照的方法和使用细胞对照的方法。本发明包括几种用于制备HbA1c细胞对照的方法，包括：（1）硼酸盐法，其中糖化发生非特异性; （2）稳定的糖尿病血液法，其中糖化特异性地发生在HbA1c上，和（3）通过控制使糖基化主要发生在HbA1c上的病症来实现的正常血液法糖化。这些方法产生具有期望稳定性的细胞Hb AIc对照，并且可以在各种仪器上检测。在优选的实施方案中，对照含有完整的红细胞。

8. 发明申请

WO1994007532A1 METHOD AND COMPOSITION FOR PRESERVING ANTIGENS AND PROCESS FOR UTILIZING CYTOLOGICAL MATERIAL PRODUCED BY SAME 审中-公开
标题翻译：用于保存抗生素的方法和组合物和利用其生产的生物材料的方法
公开(公告)号：WO1994007532A1
公开(公告)日：1994-04-14
申请号：PCT/US1993008520
申请日：1993-09-09
申请人： STRECK LABORATORIES, INC. , RYAN, Wayne, L.
发明人： STRECK LABORATORIES, INC.
IPC分类号： A61K39/12
CPC分类号： A61K39/00 , G01N1/30
摘要： A method and composition for fixing and stabilizing tissues, cells, and cell components such that the antigenic sites are preserved for a useful period of time is provided. The fixative employs a formaldehyde donor that is non-toxic, non-flammable, and that stabilizes the cell with minimal damage to and alteration of the cell morphology. The cell antigenic sites are left intact so that studies with monoclonal antibodies may be conducted. Vaccines and related immunotherapeutic methods utilizing antigens stabilized by the fixative of the present invention are also provided. The invention also discloses a method for developing a positive control for test reagents and for test instrumentation.
摘要翻译：提供了一种用于固定和稳定组织，细胞和细胞组分以使抗原位点保持一段有用时间的方法和组合物。固定剂使用无毒，不易燃的甲醛供体，并且以最小的细胞形态损伤和改变来稳定细胞。细胞抗原位点保持完整，以便可以进行用单克隆抗体的研究。还提供了使用通过本发明的固定剂稳定的抗原的疫苗和相关的免疫治疗方法。本发明还公开了一种用于开发测试试剂和测试仪器的阳性对照的方法。

9. 发明申请

WO1987005113A1 GLUCOSE REFERENCE CONTROL FOR GLUCOSE TEST STRIPS 审中-公开
标题翻译：葡萄糖测试条的葡萄糖参考控制
公开(公告)号：WO1987005113A1
公开(公告)日：1987-08-27
申请号：PCT/US1986001106
申请日：1986-05-22
申请人： STRECK LABORATORIES, INC.
发明人： STRECK LABORATORIES, INC. , RYAN, Wayne, L.
IPC分类号： G01N31/00
CPC分类号： G01N33/96 , C12Q1/54 , G01N2496/05 , Y10T436/101666 , Y10T436/104998 , Y10T436/107497 , Y10T436/108331
摘要： A stable glucose reference control has been found in which the true value and the measured value of glucose in blood, colorimetrically obtained with glucose test strips, is approximately the same. The glucose reference control comprises an aqueous suspension of: i) 40 to 500 mg/dL of glucose, and ii) about 0.1 to 0.3 x 1012/dL red blood cells fixed with a fixing agent to render the red blood cells incapable of metabolizing glucose.

10. 发明申请

US20040048386A1 Method of using cyanide-free lyse solution to emulate a cyanide-containing lyse solution in the measurement of hemoglobin 失效
标题翻译：在测量血红蛋白中使用无氰溶剂溶液来模拟含氰化物溶血溶液的方法
公开(公告)号：US20040048386A1
公开(公告)日：2004-03-11
申请号：US10408827
申请日：2003-04-07
申请人： Streck Laboratories Inc.
发明人： Jiong Wu
IPC分类号： G01N033/72
CPC分类号： G01N33/721 , Y10T436/105831 , Y10T436/25125
摘要： A method of emulating with a cyanide-free lyse solution, the measurement of hemoglobin in whole blood using a cyanide-containing lyse solution. Such an illustrative method includes: a) combining a predetermined amount of the whole blood sample with a predetermined amount of a cyanide-free lyse solution to form a mixture, b) developing the mixture to a molar absorbtivity (null) in the range of about 12.4 to 12.6 mMnull1cmnull1, and c) measuring a level of light absorbance of the mixture at a wavelength of about 540 nm. In one preferred illustrative embodiment, the cyanide-free lyse solution includes: a quaternary ammonium salt surfactant, an anionic surfactant, a hemoglobin binding agent selected from the group consisting of imidazole or hydroxylamine, and an aqueous medium. In one preferred embodiment, the molar absorbtivity is developed to a value of about 12.5 mMnull1cmnull1. That is to say to a level that is substantially identical to that of the prior art standard, cyanomethemoglobin. By achieving this level of molar absorbtivity, the final calculated results do not have to be corrected for the different molar absorbtivity exhibited by imidazolemethemoglobin or hydroxylaminemethemoglobin.
摘要翻译：使用不含氰化物的溶血溶液来模拟全血中的血红蛋白的方法，使用含氰化物的溶血溶液。这样的说明性方法包括：a）将预定量的全血样品与预定量的不含氰化物的溶解溶液组合以形成混合物，b）将混合物显影至摩尔吸光度（ε）在约 12.4至12.6mM -1 cm 3，并且c）测量该混合物在约540nm波长处的吸光度。在一个优选的说明性实施方案中，无氰化物裂解溶液包括：季铵盐表面活性剂，阴离子表面活性剂，选自咪唑或羟胺的血红蛋白结合剂和水性介质。在一个优选的实施方案中，将摩尔吸光度显影至约12.5mM -1 cm -1的值。也就是说，与现有技术标准，氰基血红蛋白基本相同的程度。通过实现该摩尔吸光度的水平，最终的计算结果不必对咪唑金属红蛋白或羟基氨基血红蛋白显示的不同摩尔吸光度进行校正。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式