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1. 发明公开

EP1574858A1 Analyte test system for determining the concentration of an analyte in a physiological or aqueous fluid 有权
标题翻译：用于确定生理液体中分析物的浓度的测试系统
公开(公告)号：EP1574858A1
公开(公告)日：2005-09-14
申请号：EP05003296.0
申请日：2005-02-16
申请人： Stiene, Matthias, Dr.
发明人： Stiene, Matthias, Dr.
IPC分类号： G01N33/52 , G01N33/487 , B01L3/00 , C12Q1/54
CPC分类号： G01N33/526 , B01L3/502707 , B01L3/502792 , B01L2300/0803 , B01L2300/0812 , B01L2300/0825 , B01L2300/0887 , B01L2300/089 , B01L2400/0406 , G01N33/54366 , Y10T156/1039 , Y10T156/1051 , Y10T156/1052
摘要： This invention provides a device for determining the concentration of an analyte like glucose, cholesterol, free fatty acids, triglycerides, proteins, ketones, phenylalanine or enzymes, in a physiological or aqueous fluid like blood, serum, plasma, saliva, urine, interstitial and/or intracellular fluid, the device having an integrated calibration and quality control system suitable for dry reagent test strips with a very small sample volume of about 0.5µL based on to a new sample distribution system. The production of the inventive analyte test element involves only a small number of uncomplicated production steps enabling an inexpensive production of the strips.
摘要翻译：本发明提供一种设备，用于确定采矿如葡萄糖，胆固醇，游离脂肪酸，甘油三酸酯，蛋白质，酮，苯丙氨酸或酶的分析物的浓度，在如血液，血清，血浆，唾液，尿液，间质和生理或wässrige流体 /或细胞内流体，具有集成的校准并适于干试剂测试条具有基于到一个新的样本分配系统的约0.5亩升的非常小的样品体积的质量控制系统中的设备，生产根据本发明的分析物测试元件都涉及只有少数的使得能够廉价地制造的带的不复杂的生产步骤。

2. 发明专利

CA2497244A1 ANALYTE TEST SYSTEM FOR DETERMINING THE CONCENTRATION OF AN ANALYTE IN A PHYSIOLOGICAL OR AQUEOUS FLUID 未知
公开(公告)号：CA2497244A1
公开(公告)日：2005-09-05
申请号：CA2497244
申请日：2005-02-14
申请人： STIENE MATTHIAS
发明人： STIENE MATTHIAS
IPC分类号： G01N21/78 , B01L3/00 , C12M1/34 , C12Q1/00 , C12Q1/26 , C12Q1/32 , C12Q1/48 , C12Q1/54 , G01N1/28 , G01N33/48 , G01N33/487 , G01N33/52 , G01N33/543 , G01N35/08 , G01N37/00
摘要： This invention provides a device for determining the concentration of an analyte like glucose, cholesterol, free fatty acids, triglycerides, proteins, ketones, phenylalani ne or enzymes, in a physiological or aqueous fluid like blood, serum, plasma, saliva, urine, interstitial and/or intracellular fluid, the device having an integrated calibration and quality control system suitable for dry reagent test strips with a very small sample volume of about 0.5.mu. L based on to a new sample distribution system. The production of the inventive analyte test element involves only a small number of uncomplicated production steps enabling an inexpensiv e production of the strips.

3. 发明申请

WO2008092639A1 RESEALABLE CONTAINER FOR STORING MOISTURE SENSITIVE TEST ELEMENTS 审中-公开
标题翻译：用于储存水分敏感测试元素的可再生容器
公开(公告)号：WO2008092639A1
公开(公告)日：2008-08-07
申请号：PCT/EP2008/000679
申请日：2008-01-29
申请人： EGOMEDICAL SWISS AG , STIENE, Matthias , JONES, Eurig, Wyn
发明人： STIENE, Matthias , JONES, Eurig, Wyn
IPC分类号： G01N33/487 , B65D81/26
CPC分类号： B65D81/266 , G01N33/48778 , Y10T29/53
摘要： A container for moisture sensitive test elements comprising a container body (2, 102, 202), an insert (22, 122, 220) fitting in container body, whereby a cavity (18, 118) is created between outer surface of insert wall (24, 124, 240) and inner surface of container body wall (4, 104, 204), and a lid (50, 150, 250) dimensioned to seal container open end when in a closed position, wherein a desiccant material is contained within the cavity (18, 118) between container body wall and insert wall. Insert wall defines a hollow channel (29, 129, 229) which is dimensioned that at least one test element extents from the insert channel facilitating accessibility to an individual test element for the testing of an analyte of interest. Desiccant material includes an indicator whose colour changes when exposed to moisture indicating to a user whether contents therein, i.e. test elements, have been compromised by environmental factors.
摘要翻译：一种用于湿气敏感测试元件的容器，包括容器主体（2,102,202），安装在容器主体中的插入件（22,122,220），由此在插入壁的外表面之间形成空腔（18,118） 24，124,240）和容器主体壁（4,104,204）的内表面，以及盖子（50,150,250），其尺寸适于在处于关闭位置时密封容器开口端，其中干燥剂材料包含在容器主体壁和插入壁之间的空腔（18,118）。插入壁限定了一个中空通道（29,129,209），其尺寸使得至少一个测试元件从插入通道延伸，便于接近单独的测试元件以测试感兴趣的分析物。干燥剂材料包括当暴露于湿气时其颜色变化的指示器，其指示用户其内容物即测试元件是否已被环境因素所影响。

4. 发明申请

WO2010063304A1 TEST ELEMENT HOLDING SYSTEM AND PERSONAL DIAGNOSTIC DEVICE COMPRISING THE SAME 审中-公开
标题翻译：测试单元保持系统和包含该测试单元的个人诊断设备
公开(公告)号：WO2010063304A1
公开(公告)日：2010-06-10
申请号：PCT/EP2008/010340
申请日：2008-12-05
申请人： EGOMEDICAL SWISS AG , STIENE, Matthias , JONES, Eurig, Wyn
发明人： STIENE, Matthias , JONES, Eurig, Wyn
IPC分类号： G01N21/86 , G01N33/487 , G01N33/52
CPC分类号： G01N33/4875 , G01N21/8483
摘要： A test element holding system for a personal diagnostic device is provided comprising a test element holder and an analyte test element for inserting into the test element holder, characterized in that the test element holder comprises first and second major structures generally arranged in a parallel formation to each other, defining a horizontal passageway of predefined width generally corresponding to at least the thickness of the test element, wherein a first engagement means for allowing pivotal engagement with a first recess of the test element and a second engagement means for releasably engaging a second recess of the test element are provided at or adjacent to the first and/or second major structures of the test element holder to allow securing of the test element within the holder by a 'hingelock' mechanism. Visible indication is provided to a user that the test element has been correctly inserted into the test element holder. Also provided is a removable protective structure for the test element holding system of the personal diagnostic device.
摘要翻译：提供了一种用于个人诊断装置的测试元件保持系统，其包括用于插入到测试元件保持器中的测试元件保持器和分析物测试元件，其特征在于，测试元件保持器包括通常以平行形式布置的第一和第二主要结构彼此限定通常对应于测试元件的厚度的预定宽度的水平通道，其中第一接合装置用于允许与测试元件的第一凹部枢转接合，以及第二接合装置，用于可释放地接合第二凹部测试元件设置在测试元件保持器的第一和/或第二主要结构处或附近，以允许通过“铰链锁定”机构将测试元件固定在保持器内。向用户提供了可见的指示，即测试元件已被正确地插入到测试元件固定器中。还提供了用于个人诊断装置的测试元件保持系统的可移除的保护结构。

5. 发明申请

WO2008092470A1 RESEALEABLE CONTAINER FOR STORING MOISTURE SENSITIVE TEST ELEMENTS 审中-公开
标题翻译：用于储存水分敏感测试元素的可回收容器
公开(公告)号：WO2008092470A1
公开(公告)日：2008-08-07
申请号：PCT/EP2007/000753
申请日：2007-01-29
申请人： EGOMEDICAL SWISS AG , STIENE, Matthias , JONES, Eurig, Wyn
发明人： STIENE, Matthias , JONES, Eurig, Wyn
IPC分类号： G01N33/487 , B65D81/26
CPC分类号： B65D81/266 , G01N33/48778 , Y10T29/53
摘要： A container for moisture sensitive test elements comprising a container body (2, 102), an insert (22, 122) fitting in container body (2, 102), whereby a cavity (18, 118) is created between outer surface of insert wall (24, 124) and inner surface of container wall (4, 104), and a lid (50) dimensioned to seal container open end when in a closed position, wherein a desiccant material is contained within the cavity (18, 118) between container body (2) and insert (22). Insert wall (24, 124) defines a hollow channel (29, 129) which is dimensioned that at least one test element extents from the insert channel (29, 129) facilitating accessibility to an individual test element for the testing of an analyte of interest. Desiccant material includes an indicator whose colour changes when exposed to moisture indicating to a user whether contents therein, i.e. test elements, have been compromised by environmental factors.
摘要翻译：一种用于湿气敏感测试元件的容器，包括容器主体（2,102），安装在容器主体（2,102）中的插入件（22,122），由此在插入件的外表面之间形成空腔（18,118）（24,124）和容器壁（4,104）的内表面，以及盖（50），其尺寸设计成在处于关闭位置时密封容器开口端，其中干燥剂材料容纳在腔（18,118）之间，容器主体（2）和插入件（22）。插入壁（24,124）限定了一个中空通道（29,129），其尺寸使得至少一个测试元件从插入通道（29,129）延伸，便于对各个测试元件的访问以便测试感兴趣的分析物。干燥剂材料包括当暴露于湿气时其颜色变化的指示器，其指示用户其内容物即测试元件是否已被环境因素所影响。

6. 发明申请

WO2007025558A8 ANALYTE TEST SYSTEM USING NON-ENZYMATIC ANALYTE RECOGNITION ELEMENTS 审中-公开
标题翻译：分析测试系统使用非酶解分析识别元件
公开(公告)号：WO2007025558A8
公开(公告)日：2007-07-26
申请号：PCT/EP2005009381
申请日：2005-08-31
申请人： EGOMEDICAL TECHNOLOGIES AG , STIENE MATTHIAS , HORSTKOTTE ELKE , KUHLMEIER DIRK , JONES EURIG WYN
发明人： STIENE MATTHIAS , HORSTKOTTE ELKE , KUHLMEIER DIRK , JONES EURIG WYN
IPC分类号： G01N33/52 , B01L3/00 , G01N21/00 , G01N33/487 , G01N33/543 , G02F1/00
CPC分类号： C12Q1/6834 , B01L3/502707 , B01L3/502761 , B01L3/502792 , B01L2200/0684 , B01L2300/0816 , B01L2300/0825 , B01L2300/0864 , B01L2300/0887 , B01L2300/089 , B01L2400/0406 , B82Y5/00 , G01N21/8483 , G01N33/526 , G01N33/54386 , G01N33/54393
摘要： An analyte test element for the qualitative and/or quantitative determination of at least one analyte in a physiological or aqueous sample fluid having a first surface (2a) and a second surface (4a) in a predetermined distance opposite from each other, said both surfaces are provided with two substantially equivalent patterns forming areas of high and low surface energy which are aligned mostly congruent, whereby the areas of high surface energy (6, 6') create a sample distribution system with at least two detection areas (6a, 6'a), said at least one of the detection areas (6a, 6'a) of the first and second surfaces (2a, 4a) is provided with at least one non-enzymatic recognition element (32). The analyte test element is suitable for analyte test systems evaluating the affinity reaction between an analyte of interest and a recognition element and therefore provides a suitable test system to perform immunoassays, receptor-assays, or other affinity assays with a simple test element containing qualitative or quantitative calibration mechanisms suitable for point of care and home settings.
摘要翻译：一种分析物测试元件，用于定性和/或定量测定具有彼此相反预定距离的第一表面（2a）和第二表面（4a）的生理或含水样品流体中的至少一种分析物，所述两个表面设有形成高和低表面能的区域的两个基本等同的图案，所述高和低表面能大致一致地对齐，由此高表面能量区域（6,6'）形成具有至少两个检测区域（6a，6'）的样本分布系统， a），所述第一和第二表面（2a，4a）的所述检测区域（6a，6'a）中的所述至少一个设置有至少一个非酶促识别元件（32）。分析物测试元件适用于评估目标分析物和识别元件之间的亲和反应的分析物测试系统，因此提供了合适的测试系统以用简单的测试元件进行免疫测定，受体测定或其他亲和测定，所述测试元件包含定性或定量校准机制适用于护理点和家庭环境。

7. 发明申请

WO2008071218A1 MONITORING DEVICE 审中-公开
标题翻译：监控设备
公开(公告)号：WO2008071218A1
公开(公告)日：2008-06-19
申请号：PCT/EP2006/012080
申请日：2006-12-14
申请人： EGOMEDICAL SWISS AG , STIENE, Matthias , JONES, Eurig, Wyn
发明人： STIENE, Matthias , JONES, Eurig, Wyn
IPC分类号： G06F19/00 , A61B5/00
CPC分类号： A61B5/4833 , A61B5/14532 , A61B5/411 , A61B5/7435 , G06F19/00 , G06F19/3456 , G06F19/3475 , G06F19/3481
摘要： Provided is a small sized, portable monitoring device capable of determining an analyte under investigation and having a system and method for providing compliance information to a user of his management of a disease, and for easily navigating a menu structure by means of manual controls). Further provided is the provision of feedback to the user in form of a disease management information to be easily understood by a user such as the further described COMPOANCE WINDOW or the INDICATOR CATEGORIES. The user interface can be used in connection with a glucose diagnostic device, a coagulation diagnostic device, immunoassay diagnostic device, and other monitoring devices such as an blood pressure monitor or a pedometer.
摘要翻译：提供了一种小型便携式监视装置，其能够确定被研究的分析物，并且具有用于向用户管理疾病的用户提供合规信息的系统和方法，并且用于通过手动控制容易地导航菜单结构）。进一步提供的是以疾病管理信息的形式向用户提供反馈，以便诸如进一步描述的COMPOANCE WINDOW或指示器类别之类的用户易于理解。用户界面可以与葡萄糖诊断装置，凝血诊断装置，免疫分析诊断装置以及诸如血压计或计步器的其它监测装置结合使用。

8. 发明申请

WO2007025558A1 ANALYTE TEST SYSTEM USING NON-ENZYMATIC ANALYTE RECOGNITION ELEMENTS 审中-公开
标题翻译：使用非酶分析识别元素的分析测试系统
公开(公告)号：WO2007025558A1
公开(公告)日：2007-03-08
申请号：PCT/EP2005/009381
申请日：2005-08-31
申请人： EGOMEDICAL TECHNOLOGIES AG , STIENE, Matthias , HORSTKOTTE, Elke , KUHLMEIER, Dirk , JONES, Eurig, Wyn
发明人： STIENE, Matthias , HORSTKOTTE, Elke , KUHLMEIER, Dirk , JONES, Eurig, Wyn
IPC分类号： G01N33/52 , G01N33/543 , G01N33/487 , B01L3/00 , G01N21/00 , G02F1/00
CPC分类号： C12Q1/6834 , B01L3/502707 , B01L3/502761 , B01L3/502792 , B01L2200/0684 , B01L2300/0816 , B01L2300/0825 , B01L2300/0864 , B01L2300/0887 , B01L2300/089 , B01L2400/0406 , B82Y5/00 , G01N21/8483 , G01N33/526 , G01N33/54386 , G01N33/54393
摘要： An analyte test element for the qualitative and/or quantitative determination of at least one analyte in a physiological or aqueous sample fluid having a first surface (2a) and a second surface (4a) in a predetermined distance opposite from each other, said both surfaces are provided with two substantially equivalent patterns forming areas of high and low surface energy which are aligned mostly congruent, whereby the areas of high surface energy (6, 6') create a sample distribution system with at least two detection areas (6a, 6'a), said at least one of the detection areas (6a, 6'a) of the first and second surfaces (2a, 4a) is provided with at least one non-enzymatic recognition element (32). The analyte test element is suitable for analyte test systems evaluating the affinity reaction between an analyte of interest and a recognition element and therefore provides a suitable test system to perform immunoassays, receptor-assays, or other affinity assays with a simple test element containing qualitative or quantitative calibration mechanisms suitable for point of care and home settings.
摘要翻译：一种分析物测试元件，用于定性和/或定量测定具有第一表面（2a）和第二表面（4a）的生理或水性样品流体中至少一种分析物彼此相对的预定距离，所述两个表面具有两个基本上等效的图案，其形成高度和低表面能的区域，其大体上等同排列，由此高表面能（6,6'）的区域产生具有至少两个检测区域（6a，6'）的样品分布系统，所述第一和第二表面（2a，4a）的所述检测区域（6a，6'a）中的至少一个设置有至少一个非酶识别元件（32）。分析物测试元件适用于分析物测试系统，用于评估感兴趣分析物与识别元件之间的亲和力反应，因此提供合适的测试系统，以进行免疫测定，受体测定或其他亲和力测定，其中包含定性或定量校准机制适用于护理点和家庭设置。

9. 发明申请

WO2005098431A1 ANALYTE TEST SYSTEM FOR DETERMINING THE CONCENTRATION OF AN ANALYTE IN A PHYSIOLOGICAL FLUID 审中-公开
标题翻译：用于确定生理流体中分析物浓度的分析测试系统
公开(公告)号：WO2005098431A1
公开(公告)日：2005-10-20
申请号：PCT/EP2004/002284
申请日：2004-03-05
申请人： EGOMEDICAL SWISS AG , STIENE, Matthias
发明人： STIENE, Matthias
IPC分类号： G01N33/52
CPC分类号： G01N33/526 , B01L3/502707 , B01L3/502792 , B01L2300/0803 , B01L2300/0812 , B01L2300/0825 , B01L2300/0887 , B01L2300/089 , B01L2400/0406 , G01N33/54366 , Y10T156/1039 , Y10T156/1051 , Y10T156/1052
摘要： This invention provides a device for determining the concentration of an analyte like glucose, cholesterol, free fatty acids, triglycerides, proteins, ketones, phenylalanine or enzymes, in a physiological fluid like blood, serum, plasma, saliva, urine, interstitial and/or intracellular fluid, the device having an integrated calibration and quality control system suitable for dry reagent test strips with a very small sample volume of about 0.5µL based on to a new sample distribution system. The production of the inventive analyte test element involves only a small number of uncomplicated production steps enabling an inexpensive production of the strips.
摘要翻译：本发明提供了一种用于在诸如血液，血清，血浆，唾液，尿，间质和/或血液的生理流体中测定分析物如葡萄糖，胆固醇，游离脂肪酸，甘油三酯，蛋白质，酮，苯丙氨酸或酶的浓度的装置。细胞内液体，该装置具有集成的校准和质量控制系统，其适用于基于新的样品分配系统的具有约0.5μL的非常小的样品体积的干试剂测试条。本发明的分析物测试元件的生产仅涉及少量不复杂的生产步骤，从而能够廉价地生产条带。

10. 发明申请

WO02078533A3 INTEGRATED SAMPLE TESTING METER 审中-公开
标题翻译：集成样品测试仪
公开(公告)号：WO02078533A3
公开(公告)日：2003-05-22
申请号：PCT/GB0201599
申请日：2002-04-02
申请人： INVERNESS MEDICAL LTD , MOERMAN PIET , SHAANAN GAD , MAINVILLE PATRICK , ORBAN BENOIT , COLEY BENJAMIN , FRANCOVICH WALTER , BODE ANDREAS , STIENE MATTHIAS , GRIFFITH ALUN
发明人： MOERMAN PIET , SHAANAN GAD , MAINVILLE PATRICK , ORBAN BENOIT , COLEY BENJAMIN , FRANCOVICH WALTER , BODE ANDREAS , STIENE MATTHIAS , GRIFFITH ALUN
IPC分类号： G01N27/28 , A61B5/15 , A61B5/151 , G01N27/416 , G01N33/487 , A61B5/00
CPC分类号： G01N33/48757 , A61B5/150022 , A61B5/150068 , A61B5/150198 , A61B5/150358 , A61B5/150412 , A61B5/150503 , A61B5/150748 , A61B5/15113 , A61B5/15117 , A61B5/1519 , A61B5/15194 , A61B5/157
摘要： An integrated sample testing meter, for instance for measuring blood, comprising a lancing device, an electrochemical sensor and a test strip cartridge disposed in a single modular housing. The test strip cartridge includes a stack of test strips suitable for performing an electrochemical or photometric analysis of a blood sample. The integrated test system automatically dispenses and positions a test strip in proximity to a lancet puncture site, automatically transfers a blood sample to the test strip from the lancet puncture site and automatically analyzes the blood sample after the test strip collects the sample from the puncture site.
摘要翻译：集成的样本测试仪器，例如用于测量血液，包括设置在单个模块化壳体中的穿刺装置，电化学传感器和测试条盒。测试条带包括适于执行血液样品的电化学或光度分析的测试条的堆叠。集成测试系统自动分配并将测试条定位在刺血针穿刺部位附近，自动将血液样本从刺血针穿刺部位转移到测试条上，并在测试条从穿刺部位收集样品后自动分析血液样本。

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