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1. 发明授权

EP0217986B1 Variable tensioning system for shear seal valves 失效
标题翻译：用于剪切密封阀的可变张力系统
公开(公告)号：EP0217986B1
公开(公告)日：1991-03-06
申请号：EP85306539.9
申请日：1985-09-13
申请人： Stearns, Stanley D.
发明人： Stearns, Stanley D.
IPC分类号： F16K5/16 , F16K3/08
CPC分类号： F16K11/0743 , F16K5/166

2. 发明公开

EP2780061A1 DELIVERY SYSTEM FOR INJECTION THROUGH ZONE OF BODY 有权
标题翻译：释放系统注射用身体区域
公开(公告)号：EP2780061A1
公开(公告)日：2014-09-24
申请号：EP12849893.8
申请日：2012-10-18
申请人： Gabriel Institute, Inc. , Stearns, Stanley D. , Loy, Max H. Jr. , Davis, Donald G.
发明人： STEARNS, Stanley, D. , LOY, Max, H.; Jr. , DAVIS, Donald, G.
IPC分类号： A61M5/20
CPC分类号： A61M5/1785 , A61M5/16886 , A61M5/172 , A61M5/2053 , A61M5/32 , A61M5/46 , A61M5/484 , A61M2202/049 , A61M2205/3334 , A61M2206/20
摘要： A dispensing device which disperses medicate through a needle across a zone within a body with zero pressure differential. The device includes a needle which is, during use, becomes encapsulated within a tubular needle-receiving member, a therapeutic agent reservoir in fluid communication with the needle, positioned within said housing, and in communication with the needle, a second reservoir, a reservoir-connecting conduit in communication with the therapeutic agent reservoir, a fluid drive in communication with the fluid in the second reservoir and in communication with said reservoir-connecting conduit, and a linear drive attached to said needle or to said needle-receiving member.

3. 发明公开

EP0217986A1 Variable tensioning system for shear seal valves 失效
标题翻译： Veränderlichspannende AnlagefürSchieber mit Scherabdichtung。
公开(公告)号：EP0217986A1
公开(公告)日：1987-04-15
申请号：EP85306539.9
申请日：1985-09-13
申请人： Stearns, Stanley D.
发明人： Stearns, Stanley D.
IPC分类号： F16K5/16 , F16K3/08
CPC分类号： F16K11/0743 , F16K5/166
摘要： This disclosure sets forth a variable tensioning system for use in a valve featuring shear seals. In the preferred and illustrated embodiment, a spring system provides loading on the valve element (18) to force that element into engagement with a valve seat (14). A sliding sealing surface is accomplished in this contact. The valve element (18) may be a tapered plug, a sphere or a flat face or plate. Typically, it is a hard member working against a seat (14) supporting a seal surface featuring a sliding shear seal. A specific minimum load is applied to the valve element (18) to accomplish sealing against minimum pressure. The present apparatus incorporates a closed chamber (24) enclosing a slideable piston (31). The piston (31) has a specific cross-sectional area exposed to fluid pressure of the fluid being controlled by the valve. The piston (31) applies pressure dependent force against the valve element (18). This adds to the force applied to the valve element (18) by a spring means (30), the two forces controllably adding to assure that the seal is sufficiently loaded to perfect a seal up to a specified maximum pressure.
摘要翻译：本公开提出了一种用于具有剪切密封件的阀的可变张紧系统。在优选和示出的实施例中，弹簧系统提供在阀元件（18）上的负载以迫使元件与阀座（14）接合。在此接触中实现滑动密封面。阀元件（18）可以是锥形塞子，球体或平面或板。典型地，它是一个坚固的构件，它抵抗支撑一个具有滑动剪切密封的密封表面的座（14）。特定的最小负载施加到阀元件（18）以实现最小压力的密封。本装置包括封闭可滑动活塞（31）的封闭腔室（24）。活塞（31）具有暴露于由阀控制的流体的流体压力的特定横截面积。活塞（31）对阀元件（18）施加压力依赖力。这增加了通过弹簧装置（30）施加到阀元件（18）的力，这两个力可控地增加以确保密封件被充分地加载以将密封件完美地达到特定的最大压力。

4. 发明授权

EP2780061B1 DELIVERY SYSTEM FOR INJECTION THROUGH ZONE OF BODY 有权
标题翻译：通过身体区域注射的输送系统
公开(公告)号：EP2780061B1
公开(公告)日：2018-02-21
申请号：EP12849893.8
申请日：2012-10-18
申请人： Gabriel Institute, Inc. , Stearns, Stanley D. , Loy, Max H. Jr. , Davis, Donald G.
发明人： STEARNS, Stanley, D. , LOY, Max, H.; Jr. , DAVIS, Donald, G.
IPC分类号： A61M5/20 , A61M5/172 , A61M5/168 , A61M5/178 , A61M5/32 , A61M5/46 , A61M5/48
CPC分类号： A61M5/1785 , A61M5/16886 , A61M5/172 , A61M5/2053 , A61M5/32 , A61M5/46 , A61M5/484 , A61M2202/049 , A61M2205/3334 , A61M2206/20
摘要： A dispensing device which disperses medicate through a needle across a zone within a body with zero pressure differential. The device includes a needle which is, during use, becomes encapsulated within a tubular needle-receiving member, a therapeutic agent reservoir in fluid communication with the needle, positioned within said housing, and in communication with the needle, a second reservoir, a reservoir-connecting conduit in communication with the therapeutic agent reservoir, a fluid drive in communication with the fluid in the second reservoir and in communication with said reservoir-connecting conduit, and a linear drive attached to said needle or to said needle-receiving member.

5. 发明授权

EP0927822B1 Valveless metering pump 失效
标题翻译：无阀计量泵
公开(公告)号：EP0927822B1
公开(公告)日：2003-10-08
申请号：EP97310661.0
申请日：1997-12-30
申请人： Stearns, Stanley D. , Werner, Paul
发明人： Stearns, Stanley D. , Werner, Paul
IPC分类号： F04B7/06
CPC分类号： F04B7/06 , F04B7/04

6. 发明公开

EP2780061A4 DELIVERY SYSTEM FOR INJECTION THROUGH ZONE OF BODY 有权
标题翻译：释放系统注射用身体区域
公开(公告)号：EP2780061A4
公开(公告)日：2015-07-08
申请号：EP12849893
申请日：2012-10-18
申请人： GABRIEL INST INC , STEARNS STANLEY D , LOY MAX H JR , DAVIS DONALD G
发明人： STEARNS STANLEY D , LOY MAX H ; JR , DAVIS DONALD G
IPC分类号： A61M5/20 , A61M5/168 , A61M5/172 , A61M5/178 , A61M5/32 , A61M5/46 , A61M5/48
CPC分类号： A61M5/1785 , A61M5/16886 , A61M5/172 , A61M5/2053 , A61M5/32 , A61M5/46 , A61M5/484 , A61M2202/049 , A61M2205/3334 , A61M2206/20
摘要： A dispensing device which disperses medicate through a needle across a zone within a body with zero pressure differential. The device includes a needle which is, during use, becomes encapsulated within a tubular needle-receiving member, a therapeutic agent reservoir in fluid communication with the needle, positioned within said housing, and in communication with the needle, a second reservoir, a reservoir-connecting conduit in communication with the therapeutic agent reservoir, a fluid drive in communication with the fluid in the second reservoir and in communication with said reservoir-connecting conduit, and a linear drive attached to said needle or to said needle-receiving member.

7. 发明公开

EP0927822A1 Valveless metering pump 失效
标题翻译： Ventillose Dosierpumpe
公开(公告)号：EP0927822A1
公开(公告)日：1999-07-07
申请号：EP97310661.0
申请日：1997-12-30
申请人： Stearns, Stanley D. , Werner, Paul
发明人： Stearns, Stanley D. , Werner, Paul
IPC分类号： F04B7/06
CPC分类号： F04B7/06 , F04B7/04
摘要： In a valveless positive displacement pump a piston 40 is rotated by a motor 12 and shaft 104 within a cylindrical housing 22 having a closed end. A cam arrangement 16 introduces reciprocating motion into shaft 104 as it rotates, with a dwell period between compression and suction strokes. The piston surface includes a fluid passage which extends to the end of the piston and which includes two intersecting helical slots. As the piston reciprocates (suction/compression) and rotates, the fluid passage is maintained in fluid coupling with an inlet/outlet port by a respective said helical slot, and during the subsequent dwell period the fluid coupling is transferred between the two ports via an intermediate state where both ports are sealed by the piston surface.
摘要翻译：在无阀正排量泵中，活塞40由具有封闭端的圆柱形壳体22内的马达12和轴104旋转。凸轮装置16在其旋转时将往复运动引入轴104中，并且在压缩和抽吸冲程之间具有停留时间段。活塞表面包括延伸到活塞的端部并且包括两个相交的螺旋槽的流体通道。当活塞往复运动（抽吸/压缩）并旋转时，流体通道通过相应的所述螺旋槽与入口/出口保持流体耦合，并且在随后的停留时段期间，流体联接通过经由两个端口都由活塞表面密封的中间状态。

8. 发明申请

WO2005024376A2 PARTIAL MODULATION VIA PULSED FLOW MODULATOR FOR COMPREHENSIVE TWO-DIMENSIONAL LIQUID OR GAS CHROMATOGRAPHY 审中-公开
标题翻译：用于全面二维液体或气相色谱的脉冲流量调节器的部分调制
公开(公告)号：WO2005024376A2
公开(公告)日：2005-03-17
申请号：PCT/US2004/026763
申请日：2004-08-19
申请人： VALCO INSTRUMENTS CO., INC. , STEARNS, Stanley, D. , CAI, Huamin
发明人： STEARNS, Stanley, D. , CAI, Huamin
IPC分类号： G01N
CPC分类号： G01N30/463 , G01N30/465 , G01N2030/383 , G01N2030/623 , Y10T436/118339 , Y10T436/255 , Y10T436/2575
摘要： This invention is a method and device for use with multi-dimensional chromatography that utilizes partial modulation. An analyte-bearing sample is subjected to a first dimension of chromatography. Thereafter the separated analyte-bearing sample is diluted with a modulated second carrier such at the analyte-bearing sample is not stopped or its temperature altered. The partially modulated analyte-bearing sample then feeds into a secondary column where the analyte-bearing sample is further separated.
摘要翻译：本发明是利用部分调制的多维色谱法使用的方法和装置。将分析物载体样品进行第一层色谱。此后，分离的含有分析物的样品用调制的第二载体稀释，使得分析物载体样品不停止或其温度改变。然后将部分调节的含有分析物的样品进料到第二柱中，其中分析物载体样品进一步分离。

9. 发明申请

WO2013074244A1 DELIVERY SYSTEM FOR INJECTION THROUGH ZONE OF BODY 审中-公开
标题翻译：通过身体部位进行注射的输送系统
公开(公告)号：WO2013074244A1
公开(公告)日：2013-05-23
申请号：PCT/US2012/060818
申请日：2012-10-18
申请人： GABRIEL INSTITUTE, INC. , STEARNS, Stanley, D. , LOY, Max, H.; Jr. , DAVIS, Donald, G.
发明人： STEARNS, Stanley, D. , LOY, Max, H.; Jr. , DAVIS, Donald, G.
IPC分类号： A61M5/20
CPC分类号： A61M5/1785 , A61M5/16886 , A61M5/172 , A61M5/2053 , A61M5/32 , A61M5/46 , A61M5/484 , A61M2202/049 , A61M2205/3334 , A61M2206/20
摘要： A dispensing device which disperses medicate through a needle across a zone within a body with zero pressure differential. The device includes a needle which is, during use, becomes encapsulated within a tubular needle-receiving member, a therapeutic agent reservoir in fluid communication with the needle, positioned within said housing, and in communication with the needle, a second reservoir, a reservoir-connecting conduit in communication with the therapeutic agent reservoir, a fluid drive in communication with the fluid in the second reservoir and in communication with said reservoir-connecting conduit, and a linear drive attached to said needle or to said needle-receiving member.
摘要翻译：一种分配装置，其通过针将药物分散在身体内的区域内，零压差。该装置包括在使用期间被封装在管状针接收构件内的针，与针流体连通的治疗剂储存器，定位在所述壳体内，并与针连通，第二储存器，储存器与治疗剂储存器连通的连接管道，与第二储存器中的流体连通并与所述储存器连接管道连通的流体驱动器，以及附接到所述针头或所述针头接收构件的线性驱动器。

10. 发明申请

WO2010129527A1 TREATMENT DELIVERY SYSTEM AND METHOD OF USE 审中-公开
标题翻译：治疗递送系统及其使用方法
公开(公告)号：WO2010129527A1
公开(公告)日：2010-11-11
申请号：PCT/US2010/033511
申请日：2010-05-04
申请人： GABRIEL INSTITUTE, INC. , STEARNS, Stanley, D. , LOY, H., Max
发明人： STEARNS, Stanley, D. , LOY, H., Max
IPC分类号： A61B17/16
CPC分类号： A61B17/1642 , A61B17/3472 , A61B2017/003
摘要： A minimally invasive and particularly small system (10) for drilling into bone (100) and for providing for delivery of medical treatment is provided. The drilling system (10) includes a miniature shaft (104), a bit (102), a guide tube (106) encapsulating the shaft (104) during drilling and a capillary tube (704) thereafter, a capillary tube (704), and a stylet (710). As a result, a hole, targeted towards a cancerous lesion within the bone, is possible. After removal of the shaft (104), the treatment may be introduced via the capillary tube (704) after removal of the stylet (710).
摘要翻译：提供了用于钻入骨头（100）并用于提供医疗处理的微创和特别小的系统（10）。钻井系统（10）包括微型轴（104），钻头（102），在钻井期间封装轴（104）的导管（106）和其后的毛细管（704），毛细管（704），和探针（710）。因此，可以有一个针对骨内癌变病变的孔。在移除轴（104）之后，可以在去除探针（710）之后通过毛细管（704）引入处理。

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