会员体验
专利管家(专利管理)
工作空间(专利管理)
风险监控(情报监控)
数据分析(专利分析)
侵权分析(诉讼无效)
联系我们
交流群
官方交流:
QQ群: 891211   
微信请扫码    >>>
现在联系顾问~
热词
    • 10. 发明申请
    • METHODS AND SYSTEMS FOR THE ANALYSIS OF BIOLOGICAL SEQUENCE DATA
    • 生物序列数据分析的方法和系统
    • WO2004113557A2
    • 2004-12-29
    • PCT/US2004/019429
    • 2004-06-18
    • APPLERA CORPORATIONLABRENZ, JamesSORENSON, Jon M.GEHMAN, Curtis
    • LABRENZ, JamesSORENSON, Jon M.GEHMAN, Curtis
    • C12Q1/00
    • G06F19/22G01N27/44721G06F19/24
    • Nucleic acid sequence determination is a method whereby peaks in data traces representing the detection of labeled nucleotides are classified as either noise or specific nucleotides. Embodiments are described herein that formulate this classification as a graph theory problem whereby graph edges encode peak characteristics. The graph can then be traversed to find the shortest path. Various embodiments formulate the graph in such a way as to minimize computational time. In various cases it is desirable that such classification allow for the possibility of mixed bases in the nucleotide sequence. Embodiments are described herein that address the classification of mixed-bases. Embodiments are also described that detail methods and systems for processing the data in order to make the classification step robust and reliable.
    • 核酸序列测定是一种方法,其中代表标记核苷酸检测的数据踪迹中的峰被分类为噪声或特定核苷酸。 本文描述了将该分类制定为图论的问题,其中图形边缘编码峰值特性。 然后可以遍历该图以找到最短路径。 各种实施例以最小化计算时间的方式来制定图形。 在各种情况下,希望这种分类允许在核苷酸序列中混合碱基的可能性。 本文描述了解决混合基底的分类的实施例。 还描述了用于处理数据以便使分类步骤稳健和可靠的详细方法和系统的实施例。