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1. 发明申请

WO2008027783A2 PROSTHETIC TESTICLE 审中-公开
标题翻译：假药
公开(公告)号：WO2008027783A2
公开(公告)日：2008-03-06
申请号：PCT/US2007/076616
申请日：2007-08-23
申请人： VANCE PRODUCTS INCORPORATED, D/B/A COOK UROLOGICAL INCORPORATED , SHIRLEY, Gary, Bradford , PAUL, Ram, H., Jr. , CASE, Brian, C.
发明人： SHIRLEY, Gary, Bradford , PAUL, Ram, H., Jr. , CASE, Brian, C.
IPC分类号： A61L27/34 , A61L27/36 , A61L27/56
CPC分类号： A61L27/56 , A61F2/0059 , A61F2/022 , A61F2230/0076 , A61F2250/0068 , A61L27/34 , A61L27/3641 , C08L75/04
摘要： A prosthetic testicle is provided that is able to mimic the movement and feel of a natural testicle while at the same time being able to remodel itself into native tissue. Additionally, the prosthetic testicle is able to provide long-term delivery of drugs into the patient.
摘要翻译：提供了能够模仿天然睾丸的运动和手感的同时可以将自身改造成天然组织的假体睾丸。此外，假体睾丸能够向患者提供药物的长期输送。

2. 发明申请

WO2008027783A3 PROSTHETIC TESTICLE 审中-公开
标题翻译：假药
公开(公告)号：WO2008027783A3
公开(公告)日：2009-02-12
申请号：PCT/US2007076616
申请日：2007-08-23
申请人： VANCE PRODUCTS INC , SHIRLEY GARY BRADFORD , PAUL RAM H JR , CASE BRIAN C
发明人： SHIRLEY GARY BRADFORD , PAUL RAM H JR , CASE BRIAN C
IPC分类号： A61L27/34 , A61L27/36 , A61L27/54 , A61L27/56
CPC分类号： A61L27/56 , A61F2/0059 , A61F2/022 , A61F2230/0076 , A61F2250/0068 , A61L27/34 , A61L27/3641 , C08L75/04
摘要： A prosthetic testicle is provided that is able to mimic the movement and feel of a natural testicle while at the same time being able to remodel itself into native tissue. Additionally, the prosthetic testicle is able to provide long-term delivery of drugs into the patient. The prosthetic testicle comprises an. interior having a testicular, shape and. a porous coating covering, the interior.
摘要翻译：提供了能够模仿天然睾丸的运动和手感的同时可以将自身改造成天然组织的假体睾丸。此外，假体睾丸能够向患者提供药物的长期输送。假体睾丸包括。内部有睾丸，形状和。一个多孔的涂层覆盖着内部。

3. 发明申请

WO2008097511A3 MEDICAL DEVICE COATINGS FOR RELEASING A THERAPEUTIC AGENT AT MULTIPLE RATES 审中-公开
公开(公告)号：WO2008097511A3
公开(公告)日：2008-08-14
申请号：PCT/US2008/001455
申请日：2008-02-04
申请人： COOK INCORPORATED , SHIRLEY, Gary, Bradford , MOORE, William, F.
发明人： SHIRLEY, Gary, Bradford , MOORE, William, F.
IPC分类号： A61L27/54 , A61L31/16
摘要： Medical device coatings are provided that simultaneously release a therapeutic agent at different rates from different portions of the medical device coating. In a first embodiment, medical device coatings are provided that include particles comprising a therapeutic agent with two or more different particles sizes within a single layer on a surface of the implantable device. In a second embodiment, medical device coating are provided having a higher concentration of the therapeutic agent in a first region of the coating than in a second region of the coating. In a third embodiment, medical device coatings are provided that are formed by certain coating processes wherein the droplet size of a spray coating solution is changed during the coating process. These coating processes preferably include applying a solution comprising a therapeutic agent and a suitable solvent to a surface of an implantable medical device. In a fourth embodiment, methods of treatment are provided that include implanting a coated medical device.

4. 发明申请

WO2008097511A2 MEDICAL DEVICE COATINGS FOR RELEASING A THERAPEUTIC AGENT AT MULTIPLE RATES 审中-公开
标题翻译：用于以多种方式释放治疗药物的医疗装置涂料
公开(公告)号：WO2008097511A2
公开(公告)日：2008-08-14
申请号：PCT/US2008001455
申请日：2008-02-04
申请人： COOK INC , SHIRLEY GARY BRADFORD , MOORE WILLIAM F
发明人： SHIRLEY GARY BRADFORD , MOORE WILLIAM F
IPC分类号： A61F2/958 , A61L27/34 , A61L27/54 , A61L31/10 , A61L31/16
CPC分类号： A61L31/08 , A61F2/90 , A61F2240/00 , A61L27/34 , A61L27/54 , A61L29/08 , A61L29/16 , A61L31/10 , A61L31/16 , A61L2300/416
摘要： Medical device coatings are provided that simultaneously release a therapeutic agent at different rates from different portions of the medical device coating. In a first embodiment, medical device coatings are provided that include particles comprising a therapeutic agent with two or more different particles sizes within a single layer on a surface of the implantable device. In a second embodiment, medical device coating are provided having a higher concentration of the therapeutic agent in a first region of the coating than in a second region of the coating. In a third embodiment, medical device coatings are provided that are formed by certain coating processes wherein the droplet size of a spray coating solution is changed during the coating process. These coating processes preferably include applying a solution comprising a therapeutic agent and a suitable solvent to a surface of an implantable medical device. In a fourth embodiment, methods of treatment are provided that include implanting a coated medical device.
摘要翻译：提供了医疗装置涂层，其同时以与医疗装置涂层的不同部分不同的速率释放治疗剂。在第一实施例中，提供了医疗装置涂层，其包括在可植入装置的表面上的单层内包含具有两种或更多种不同粒径的治疗剂的颗粒。在第二个实施方案中，提供了在涂层的第一区域中具有比在涂层的第二区域更高浓度的治疗剂的医疗器械涂层。在第三实施例中，提供了通过某些涂覆方法形成的医疗装置涂层，其中在涂覆过程中喷雾涂层溶液的液滴尺寸改变。这些涂覆方法优选包括将包含治疗剂和合适溶剂的溶液施用到可植入医疗装置的表面。在第四实施例中，提供了包括植入涂覆的医疗装置的治疗方法。

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