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1. 发明专利

SG11201601486TA HETEROCYCLIC COMPOUNDS AND METHODS OF USE 未知
公开(公告)号：SG11201601486TA
公开(公告)日：2016-03-30
申请号：SG11201601486T
申请日：2014-08-28
申请人： CHAKRAVARTY SARVAJIT , RAI ROOPA , PHAM SON MINH , PUJALA BRAHMAM , JANGIR RAMNIWAS , GUGULOTH RAMBABU , SHARMA VIJAY KUMAR
发明人： CHAKRAVARTY SARVAJIT , RAI ROOPA , PHAM SON MINH , PUJALA BRAHMAM , JANGIR RAMNIWAS , GUGULOTH RAMBABU , SHARMA VIJAY KUMAR
IPC分类号： A61K31/4745 , C07D471/04
摘要： This disclosure provides compounds and methods of using those compounds to treat metabolic disorders and hyperproliferative disorders, including administration of the compounds in conjunction with hormone receptor antagonists.

2. 发明专利

ZA202200321B A SMART HEALTHCARE SYSTEM AND A METHOD THEREOF 未知
公开(公告)号：ZA202200321B
公开(公告)日：2022-06-29
申请号：ZA202200321
申请日：2022-01-06
申请人： SRIVASTAVA SWARAJ , YADAV AYUSH , SHARMA VIJAY KUMAR
发明人： SRIVASTAVA SWARAJ , YADAV AYUSH , SHARMA VIJAY KUMAR

3. 发明专利

ZA202202792B A BIOMETRIC-BASED AUTOMATED LIQUID DISPENSER SYSTEM AND A METHOD THEREOF 未知
公开(公告)号：ZA202202792B
公开(公告)日：2022-05-25
申请号：ZA202202792
申请日：2022-03-08
申请人： YADAV AYUSH , SHARMA VIJAY KUMAR
发明人： YADAV AYUSH , SHARMA VIJAY KUMAR

4. 发明申请

WO2012118943A1 SYNTHESIS OF INTERMEDIATE FOR TREPROSTINIL PRODUCTION 审中-公开
标题翻译：合成中草药生产
公开(公告)号：WO2012118943A1
公开(公告)日：2012-09-07
申请号：PCT/US2012/027234
申请日：2012-03-01
申请人： UNITED THERAPEUTICS CORPORATION , SHARMA, Vijay
发明人： SHARMA, Vijay
IPC分类号： C07D315/00 , C07F7/04 , C07F7/08
CPC分类号： C07C51/00 , C07C45/42 , C07C45/68 , C07C47/575 , C07C213/08 , C07F1/08 , C07C217/68
摘要： The compound according to Formula I is an intermediate in the synthesis of prostacylin analogs. The present invention provides an efficient method for synthesizing a Formula I compound.
摘要翻译：根据式I的化合物是前列腺酰胆碱类似物的合成中的中间体。本发明提供了合成式I化合物的有效方法。

5. 发明申请

WO2011140329A1 TRANSGENIC PLANTS HAVING INCREASED BIOMASS 审中-公开
标题翻译：具有增加生物量的转基因植物
公开(公告)号：WO2011140329A1
公开(公告)日：2011-11-10
申请号：PCT/US2011/035345
申请日：2011-05-05
申请人： CERES, INC. , APUYA, Nestor , SHARMA, Vijay , WU, Chuan-Yin
发明人： APUYA, Nestor , SHARMA, Vijay , WU, Chuan-Yin
IPC分类号： A01H5/00 , C12N15/29 , C12Q1/68 , A01H5/10 , C12N15/54
CPC分类号： C12N15/8242 , C07K14/415 , C12N9/1048 , C12N15/8261 , C12Q1/6895 , C12Q2600/13 , Y02A40/146
摘要： Methods and materials for modulating biomass levels in plants are disclosed. For example, nucleic acids encoding biomass-modulating polypeptides are disclosed as well as methods for using such nucleic acids to transform plant cells. Also disclosed are plants having increased biomass levels and plant products produced from plants having increased biomass levels.
摘要翻译：公开了调节植物生物量的方法和材料。例如，公开了编码生物质调节多肽的核酸以及使用这种核酸转化植物细胞的方法。还公开了具有增加的生物量水平的植物和由具有增加的生物量水平的植物产生的植物产品。

6. 发明申请

WO2010109488A2 A DEVICE FOR TRANSFERRING VOLATILE LIQUIDS FROM A CONTAINER TO A VAPORIZER 审中-公开
标题翻译：用于将挥发性液体从容器转移到蒸发器的装置
公开(公告)号：WO2010109488A2
公开(公告)日：2010-09-30
申请号：PCT/IN2010000175
申请日：2010-03-23
申请人： PIRAMAL HEALTHCARE LTD , BHOWMIK BIKRAM , MISHRA RAJESH , SAKHARDANDE MANISHA , SHARMA VIJAY
发明人： BHOWMIK BIKRAM , MISHRA RAJESH , SAKHARDANDE MANISHA , SHARMA VIJAY
CPC分类号： A61M16/183 , A61M2205/6045
摘要： The invention embodies a device for transferring volatile fluid from a container to a receiver, including an anesthetic fluid, comprising a mechanism adapted to a fluid transfer through a sequence of opening and closing of sealing elements wherein the sealing element at receiver end opens first, followed by opening of sealing element at container end to connect the container with the receiver through a fluid passage path, and disconnects fluid passage path first by closing a sealing element at receiver subassembly end and then closing the sealing element at receiver end. Illustrated embodiments comprise a receiver subassembly and an receiver subassembly having mechanisms such that a sequence of movement of the receiver subassembly with reference to receiver subassembly sets in motion the desired sequence of opening and closing of the sealing elements given above. The illustrated movements include (a) rotate the receiver subassembly around its axis in two sequential actions concurrent to movement along its axis towards the receiver subassembly, and reverse the action, (b) rotate the receiver subassembly along its axis and then axially push the same towards the receiver subassembly, and (c) push the receiver subassembly into the receiver subassembly.
摘要翻译：本发明体现了一种用于将挥发性流体从容器转移到接收器的装置，包括麻醉流体，包括适于通过密封元件的打开和关闭序列的流体传递的机构，其中接收器端处的密封元件首先打开，随后通过在容器端处打开密封元件，以通过流体通道路径将容器与接收器连接起来，并且通过在接收器组件端处封闭密封元件然后在接收器端封闭密封元件，首先断开流体通道路径。说明的实施例包括接收器子组件和接收器子组件，其具有这样的机构，使得接收器子组件参考接收器子组件的运动序列使上述给出的密封元件的打开和关闭的期望顺序运动。所示的运动包括（a）以两个顺序的动作使接收器子组件绕其轴线旋转，同时沿其轴线朝向接收器子组件移动，并且反转该动作，（b）使接收器子组件沿其轴线旋转，然后轴向推动相同朝向接收器子组件，以及（c）将接收器子组件推入接收器子组件。

7. 发明申请

WO2006009874A3 METHODS AND COMPOSITIONS FOR TREATMENT OF EXCESS NITRIC OXIDE OR CYANIDE TOXICITY 审中-公开
标题翻译：用于治疗过氧化氮或氰化物毒性的方法和组合
公开(公告)号：WO2006009874A3
公开(公告)日：2006-05-26
申请号：PCT/US2005021535
申请日：2005-06-17
申请人： UNIV CALIFORNIA , BOSS GERRY , SHARMA VIJAY , BRODERICK KATE E
发明人： BOSS GERRY , SHARMA VIJAY , BRODERICK KATE E
IPC分类号： A61K31/70
CPC分类号： A61K31/70
摘要： Methods for treating disease states in a subject caused or exacerbated by the presence of excess nitric oxide (NO) or excess cyanide are provided. Methods for alleviating the symptoms of a disease state in a subject caused or exacerbated by the presence of excess nitric oxide (NO) or excess cyanide in the subject are also provided. Pharmaceutical compositions comprising cobinamide and a pharmaceutically acceptable carrier are also provided.
摘要翻译：提供用于治疗受试者中由于存在过量一氧化氮（NO）或过量氰化物引起或加剧的疾病状态的方法。还提供了减轻受试者中过量一氧化氮（NO）或过量氰化物的存在引起或加剧的受试者疾病状态症状的方法。还提供了包含联苯胺和药学上可接受的载体的药物组合物。

8. 发明申请

WO2011153363A1 TREPROSTINIL PRODUCTION 审中-公开
标题翻译：曲妥珠单抗生产
公开(公告)号：WO2011153363A1
公开(公告)日：2011-12-08
申请号：PCT/US2011/038946
申请日：2011-06-02
申请人： UNITED THERAPEUTICS CORPORATION , BATRA, Hitesh , PENMASTA, Raju , SHARMA, Vijay , TULADHAR, Sudersan M. , WALSH, David A.
发明人： BATRA, Hitesh , PENMASTA, Raju , SHARMA, Vijay , TULADHAR, Sudersan M. , WALSH, David A.
IPC分类号： C07C62/00
CPC分类号： C07C51/00 , C07B2200/07 , C07C29/143 , C07C29/42 , C07C45/00 , C07C45/29 , C07C45/61 , C07C45/64 , C07C51/09 , C07C51/367 , C07C59/72 , C07C67/343 , C07C253/30 , C07F7/1892 , Y02P20/55 , C07C69/736 , C07C255/13
摘要： A method is disclosed for preparing a synthetic intermediate for treprostinil via a stereoselective alkyne addition reaction using a chiral inducing agent. Also described are methods of preparing treprostinil or a pharmaceutically acceptable salt thereof comprising the alkyne addition reaction as well as novel intermediates useful for synthesis prostacyclin derivatives. A functional alcohol protecting group protects the alcohol group from participating in reactions that are occurring in other parts of the molecule. The intermediate is later deprotected prior to conversion and hydrolyzing to obtain the final treprostinil product.
摘要翻译：公开了一种通过使用手性诱导剂通过立体选择性炔加成反应制备曲前列环素的合成中间体的方法。还描述了制备包含炔炔加成反应的曲前列素或其药学上可接受的盐的方法以及可用于合成前列环素衍生物的新中间体。功能性醇保护基保护酒精组不参与在分子的其它部分发生的反应。中间体在转化和水解之前随后被去保护以获得最终的曲前列环素产品。

9. 发明申请

WO2011070591A3 A DEVICE FOR SPILLAGE FREE TRANSFERRING VOLATILE LIQUIDS FROM A BOTTLE TO THE RESERVOIR OF A VAPORISER. 审中-公开
标题翻译：一种用于将挥发性液体从瓶子传送到蒸发器储存器的泄漏装置。
公开(公告)号：WO2011070591A3
公开(公告)日：2011-11-24
申请号：PCT/IN2010000792
申请日：2010-12-07
申请人： PIRAMAL HEALTHCARE LTD , MISHRA RAJESH , SAKHARDANDE MANISHA , SHARMA VIJAY , BHOWMIK BIKRAM
发明人： MISHRA RAJESH , SAKHARDANDE MANISHA , SHARMA VIJAY , BHOWMIK BIKRAM
IPC分类号： B65B1/04
CPC分类号： A61M16/183 , A61M2205/6045
摘要： A device and a method for transferring volatile fluid from a container to a receive, said device comprising an adapter secured to said container and a receiver subassembly secured to said receiver; said adapter and receiver subassembly provided with components complementary to one another and movable sealing elements adapted to selectively engage with one other such that in an operative receiver filling configuration, movement of the adapter relative to receiver subassembly leads to first open the sealing element in receiver subassembly to connect fluid path to the receiver and next open the sealing element in the adapter to connect a fluid passage path from the container to the receiver subassembly, and in an operative stopfilling configuration, the movement of adapter relative to receiver subassembly in reverse direction leads to close the sealing element of the adapter prior to closure of the sealing element in the receiver subassembly.
摘要翻译：一种用于将挥发性流体从容器传送到接收器的装置和方法，所述装置包括固定到所述容器的适配器和固定到所述接收器的接收器子组件; 所述适配器和接收器子组件设置有彼此互补的部件和适于选择性地彼此接合的可移动密封元件，使得在可操作的接收器填充构型中，适配器相对于接收器子组件的移动首先将接收器子组件中的密封元件打开将流体路径连接到接收器，然后打开适配器中的密封元件以将流体通道从容器连接到接收器子组件，并且在可操作的停止填充配置中，适配器相对于接收器子组件的相反方向的移动导致在接收器子组件中的密封元件关闭之前关闭适配器的密封元件。

10. 发明申请

WO2011070591A2 A DEVICE FOR SPILLAGE FREE TRANSFERRING VOLATILE LIQUIDS FROM A BOTTLE TO THE RESERVOIR OF A VAPORISER. 审中-公开
标题翻译：一种用于免费将挥发性液体从瓶子传送到蒸发器的储存器的装置。
公开(公告)号：WO2011070591A2
公开(公告)日：2011-06-16
申请号：PCT/IN2010/000792
申请日：2010-12-07
申请人： PIRAMAL HEALTHCARE LTD. , MISHRA, Rajesh , SAKHARDANDE, Manisha , SHARMA, Vijay , BHOWMIK, Bikram
发明人： MISHRA, Rajesh , SAKHARDANDE, Manisha , SHARMA, Vijay , BHOWMIK, Bikram
IPC分类号： B67D7/38
CPC分类号： A61M16/183 , A61M2205/6045
摘要： This invention embodies a device and a method for transferring volatile fluid from a container to a receiver using the said device, the said device comprising an adapter configured to be secured to said container and a receiver sub assembly adapted to be secured to said receiver; said adapter and receiver sub assembly provided with components complementary to one another and movable sealing elements adapted to selectively engage with one other such that in an operative receiver filling configuration, movement of the adapter relative to receiver sub assembly leads to first open the sealing element in receiver sub assembly to connect fluid path to the receiver and next open the sealing element in the adapter to connect a fluid passage path from the container to the receiver sub assembly, and in an operative stop- filling configuration, the movement of adapter relative to receiver sub assembly in reverse direction leads to close the sealing element of the adapter prior to closure of the sealing element in the receiver sub assembly; characterized in that in an operative configuration the adapter and the receiver sub assembly are configured to be linked to one another by engagement of said complementary components and relative movement of the components of said receiver sub assembly sealing element is linear along its axis and of the said adapter sealing element is angular/rotational around its axis.
摘要翻译：本发明体现了使用所述装置将挥发性流体从容器转移到接收器的装置和方法，所述装置包括被配置为固定到所述容器的适配器和适于固定到所述接收器的接收器子组件; 所述适配器和接收器子组件设置有彼此互补的部件和适于选择性地彼此接合的可移动密封元件，使得在可操作的接收器填充构型中，适配器相对于接收器子组件的移动首先将密封元件打开接收器子组件以将流体路径连接到接收器，并且接下来打开适配器中的密封元件以连接从容器到接收器子组件的流体通道路径，并且在可操作的停止填充配置中，适配器相对于接收器的移动副组件反向导致在接收器子组件中的密封元件关闭之前关闭适配器的密封元件; 其特征在于，在可操作的构造中，适配器和接收器子组件被配置为通过所述互补部件的接合而彼此连接，并且所述接收器子组件密封元件的部件的相对运动沿其轴线和所述适配器密封元件围绕其轴线具有角/旋转。

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