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1. 发明申请

US20210186557A1 SURGERY MULTICHANNEL DEVICE 有权
公开(公告)号：US20210186557A1
公开(公告)日：2021-06-24
申请号：US16620004
申请日：2018-06-06
申请人： SERVIZO GALEGO DE SAÚDE (SERGAS)
发明人： José Francisco NOGUERA AGUILAR , Javier AGUIRREZABALAGA GONZÁLEZ , Alberto CENTENO CORTÉS
IPC分类号： A61B17/34
摘要： The invention provides a pneumatic sealing system device which allows sealing a working channel, a surgery multichannel device comprising a pneumatic sealing system and a method for installing said pneumatic sealing system on a multichannel device. The device is a mentioned instruments simultaneously.

2. 发明授权

US11571240B2 Surgery multichannel device 有权
公开(公告)号：US11571240B2
公开(公告)日：2023-02-07
申请号：US16620004
申请日：2018-06-06
申请人： SERVIZO GALEGO DE SAÚDE (SERGAS)
发明人： José Francisco Noguera Aguilar , Javier Aguirrezabalaga González , Alberto Centeno Cortés
IPC分类号： A61B17/34 , A61B17/00
摘要： The invention provides a pneumatic sealing system device which allows sealing a working channel, a surgery multichannel device comprising a pneumatic sealing system and a method for installing said pneumatic sealing system on a multichannel device. The device is a mentioned instruments simultaneously.

3. 发明申请

US20220113320A1 IN VITRO METHOD FOR THE DIAGNOSIS OR PROGNOSIS OF NEURODEGENERATIVE DISORDERS 有权
公开(公告)号：US20220113320A1
公开(公告)日：2022-04-14
申请号：US17422102
申请日：2020-01-10
申请人： FUNDACIÓN BIOMÉDICA GALICIA SUR (FBGS) , SERVIZO GALEGO DE SAÚDE (SERGAS) , UNIVERSIDAD DE VIGO
发明人： Carlos SPUCH CALVAR , Tania RIVERA BALTANÁS , Jose Manuel OLIVARES DÍAZ , Miguel Ángel CORREA DUARTE , Moisés PEREZ LORENZO , Verónica SALGUEIRIÑO MACEIRA , Ana SOUSA CASTILLO , Maria BLANCO FORMOSO
IPC分类号： G01N33/68
摘要： The present invention is focused on an in vitro method for the diagnosis or prognosis of neurodegenerative disorders. The method comprises measuring the level of expression or the concentration level of at least a lipoprotein receptor-related protein fragment (LRP fragment) or at least a lipoprotein receptor-related protein (LRP).

4. 外观设计

USD993408S1 Catheter insertion device 有权
公开(公告)号：USD993408S1
公开(公告)日：2023-07-25
申请号：US29736594
申请日：2020-06-01
申请人： SERVIZO GALEGO DE SAÚDE (SERGAS)
设计人： Alejandro Montero Salinas , Antón Fernández García , Fernando Mosteiro Pereira
摘要： The patent or application file contains at least one drawing executed in color. Copies of this patent or patent application publication with color drawing(s) will be provided by the Office upon request and payment of the necessary fee.
FIG. 1 is a side view of a catheter insertion device;
FIG. 2 is another side view thereof;
FIG. 3 is a front view thereof;
FIG. 4 is a rear view thereof;
FIG. 5 is a bottom view thereof; and,
FIG. 6 is a top view thereof.
The portions in broken lines illustrate environment do not form part of the claimed design. The lettering and numerals on one side of one tube does not form part of the claimed design.

5. 发明申请

US20200064358A1 METHOD FOR PROGNOSIS OF THE OUTCOME OF PATIENTS WITH HEART FAILURE (HF) 审中-公开
公开(公告)号：US20200064358A1
公开(公告)日：2020-02-27
申请号：US16488067
申请日：2018-02-28
申请人： FUNDACIÓN INSTITUTO DE INVESTIGACIÓN SANITARIA DE SANTIAGO DE COMPOSTELA , SERVIZO GALEGO DE SAÚDE (SERGAS) , UNIVERSIDADE DE SANTIAGO DE COMPOSTELA
发明人： José Ramón GONZÁLEZ JUANATEY , Rosa Mª BERMEJO AGRA , Sonia EIRAS PENAS
IPC分类号： G01N33/68 , A61B5/02
摘要： The present invention offers a solution to the lack of a novel and efficient method capable to predict the outcome of patients with HF. In this context, patients with a bad prognosis are expected to be hospitalized or die in the incoming years following the diagnosis of HF, due to the HF, or due to a complication of the HF. This method is based on the concentration of Orosomucoid (APG) and Omentin in an isolated blood sample from the patient. In this sense, a high concentration of AGP and a low concentration of Omentin in blood are associated with a bad prognosis. This improved method of prognosis is aimed to help on the design of the most appropriate treatment for the patient.

6. 发明申请

US20200173997A1 CHOLESTERYL LINOLEATE (18:2) IN FECES SAMPLES AS BIOMARKER FOR COLORECTAL CANCER 审中-公开
公开(公告)号：US20200173997A1
公开(公告)日：2020-06-04
申请号：US16612343
申请日：2018-05-11
申请人： SERVIZO GALEGO DE SAÚDE (SERGAS) , ASOCIACIÓN CENTRO DE INVESTIGACIÓN COOPERATIVA EN BIOCIENCIAS - CIC BIOGUNE , ADMINISTRACIÓN GENERAL DE LA COMUNIDAD AUTÓNOMA DE EUSKADI , CENTRO DE INVESTIGACIÓN BIOMÉDICA EN RED
发明人： Joaquín CUBIELLA FERNÁNDEZ , Juan Manuel FALCÓN PÉREZ , Luis BUJANDA FERNÁNDEZ DE PIEROLA
IPC分类号： G01N33/574 , G01N33/92 , G16H50/70
摘要： The present invention relates to biomarkers for colorectal cancer. Specifically, it relates to metabolic markers as a screening, diagnostic or monitoring tool for detecting colorectal cancer (CRC) and/or advanced adenoma (AD) in a subject. In a particular embodiment, it refers to an in vitro method for the screening, diagnosis or monitoring of colorectal cancer and/or advanced adenoma in a subject, said method comprising the following steps: a) determining the levels of the metabolic marker ChoE(18:2) in a feces sample isolated from said subject; b) comparing the levels in said feces sample with a reference value; wherein an increase of ChoE(18:2) levels in the subject sample with regard to said reference value is indicative of CRC and/or AD.

7. 发明授权

US11230694B2 Antimicrobial strain 有权
公开(公告)号：US11230694B2
公开(公告)日：2022-01-25
申请号：US16463348
申请日：2017-11-24
申请人： SERVIZO GALEGO DE SAÚDE (SERGAS) , UNIVERSIDADE DE SANTIAGO DE COMPOSTELA (USC)
发明人： Lucía Martínez Lamas , Maximiliano Álvarez Fernández , Pedro Diz Dios , Jacobo Limeres Posse
IPC分类号： C12N1/20 , A23L33/135 , A61K9/00 , C12R1/46
摘要： The present invention belongs to the field of the biotechnology, and relates to novel Streptococcusbacteria which are useful as antimicrobial agents, particularly against caries and periodontal disease. The invention relates to compositions and functional food comprising the novel bacteria. In particular, the present invention relates to a novel bacterial strain, deposited at the Colección Española de Cultivos Tipo, with accession number CECT 9174, which has proven to be useful in the prevention and treatment of caries and periodontal disease.

8. 发明申请

US20180153897A1 RIBOFLAVIN FOR THE TREATMENT OF ISCHEMIC STROKE AND/OR OTHER GLUTAMATE EXCITOTOXICITY-ASSOCIATED DISEASES 审中-公开
公开(公告)号：US20180153897A1
公开(公告)日：2018-06-07
申请号：US15571764
申请日：2016-05-04
申请人： UNIVERSIDADE DE SANTIAGO DE COMPOSTELA , SERVIZO GALEGO DE SAÚDE (SERGAS) , FUNDACIÓN RAMÓN DOMÍNGUEZ
发明人： José Manuel BREA FLORIANI , Francisco CAMPOS PÉREZ , José CASTILLO SÁNCHEZ , Mª Isabel LOZA GARCÍA , Tomás SOBRINO MOREIRAS
IPC分类号： A61K31/525 , A61K31/19 , A61K31/22 , A61K9/00 , A61P9/10 , A61P25/00
CPC分类号： A61K31/525 , A61K9/0019 , A61K31/19 , A61K31/22 , A61K2300/00 , A61P9/10 , A61P25/00
摘要： The present invention relates to a combination therapy comprising the use of riboflavin and oxaloacetate. Specifically, it is directed to new compositions, pharmaceutical compositions, kits of parts and methods for treating ischemic stroke and/or other excitotoxicity-associated diseases. It further relates to riboflavin for use in the therapeutic treatment of acute ischemic stroke by intravascular administration within the first twelve hours of symptom onset.

9. 发明申请

WO2018224557A1 SURGERY MULTICHANNEL DEVICE 审中-公开
公开(公告)号：WO2018224557A1
公开(公告)日：2018-12-13
申请号：PCT/EP2018/064913
申请日：2018-06-06
申请人： SERVIZO GALEGO DE SAÚDE (SERGAS)
发明人： NOGUERA AGUILAR, José Francisco , AGUIRREZABALAGA GONZÁLEZ, Javier , CENTENO CORTÉS, Alberto
IPC分类号： A61B17/34
摘要： The invention provides a pneumatic sealing system device which allows sealing a working channel, a surgery multichannel device comprising a pneumatic sealing system and a method for installing said pneumatic sealing system on a multichannel device. The device is a mentioned instruments simultaneously.

10. 发明申请

WO2017194779A1 USE OF ANTI-CD26 ANTIBODY LEVELS AS AUTOIMMUNE AND/OR INFLAMMATORY DISEASE BIOMARKERS 审中-公开
标题翻译：使用抗-CD26抗体水平作为自身免疫和/或炎性疾病生物标志物
公开(公告)号：WO2017194779A1
公开(公告)日：2017-11-16
申请号：PCT/EP2017/061537
申请日：2017-05-12
申请人： SERVIZO GALEGO DE SAÚDE (SERGAS) , UNIVERSIDADE DE SANTIAGO DE COMPOSTELA
发明人： PEGO REIGOSA, José María , CORDERO SANTAMARÍA, Óscar , VARELA CALVIÑO, Rubén
IPC分类号： A61K31/00 , G01N33/564
摘要： The present invention relates to the use of anti-CD26 antibodies as markers for the screening, diagnosis or monitoring of human subjects having, or suspected to have an autoimmune and/or inflammatory disease, such as rheumatoid arthritis, in particular those in an early stage of the disease. More specifically, itrefersto an invitromethod for the screening of a subjecthaving,or suspected of having an autoimmune and/orinflammatory disease, such as rheumatoid arthritis, comprising the following steps: a)determining the levels of anti-CD26 IgG antibodies in an antibody-containing sample isolated from said subject; b)comparing the levels in said antibody-containing sample with a reference value; wherein an increase of the anti-CD26 IgG antibody levels in the subject sample with regard to said reference value is indicative of disease; and wherein said reference value corresponds to the anti-CD26 IgG antibody mean levels in healthy subjects.
摘要翻译：本发明涉及抗CD26抗体作为筛选，诊断或监测患有或疑似患有自身免疫性和/或炎症性疾病如人类风湿性关节炎特别是那些处于疾病早期阶段的人。更具体地说，它涉及筛选患有或疑似患有自身免疫性和/或炎症性疾病如类风湿性关节炎的受试者的方法，包括以下步骤：a）测定含有抗体的患者中抗CD26IgG抗体的水平从所述受试者分离的样品; b）将所述含有抗体的样品中的水平与参考值进行比较; 其中受试者样品中抗CD26IgG抗体水平相对于所述参考值的增加指示疾病; 并且其中所述参考值对应于健康受试者中的抗CD26IgG抗体平均水平。

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