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1. 发明申请

WO2012145073A1 BASKET STYLE CARDIAC MAPPING CATHETER HAVING SPLINE BENDS FOR DETECTION OF CARDIAC RHYTHM DISORDERS 审中-公开
标题翻译：具有检测心脏疾病症状的线索的篮式风格护理导管
公开(公告)号：WO2012145073A1
公开(公告)日：2012-10-26
申请号：PCT/US2012/027182
申请日：2012-03-01
申请人： TOPERA, INC. , KORDIS, Thomas, F. , SEHRA, Ruchir , JOHNSON, Eric, T. , RAGLAND, Robert, Ryan , KENT, Darrin, J.
发明人： KORDIS, Thomas, F. , SEHRA, Ruchir , JOHNSON, Eric, T. , RAGLAND, Robert, Ryan , KENT, Darrin, J.
IPC分类号： A61B5/042
CPC分类号： A61B5/0422 , A61B5/042 , A61B5/6858 , A61B5/6859 , A61B18/1492 , A61B2018/0016 , A61B2018/00267 , A61B2018/00351 , A61B2562/17 , F04C2270/0421 , Y10T29/49117
摘要： A system (10) for sensing multiple local electric voltages from endocardial surface of a heart, may comprise: a first elongate tubular member (20); a basket assembly (12) comprising: a plurality of flexible splines (14); a proximal anchor (18) for securably affixing the proximal portions (62) of the splines (14); said proximal anchor (18) being secured at the distal end (20B) of the first elongate tubular member (20); a distal tip (16) for securably affixing the distal portions (66) of the splines (14), said proximal anchor (18) and said distal tip (16) defining a longitudinal axis therein between about which the splines (14) are disposed; wherein the splines (14) approach the distal tip (18) at an angle (a) of about 90° or less; wherein the splines (14) in the radially expanded non - spherical shape contain a distal excurvate outward bend (80) disposed at the distal portion (66) of the spline (14) to bend the splines (14) back towards the proximal anchor (18).
摘要翻译：用于从心脏的心内膜表面感测多个局部电压的系统（10）可以包括：第一细长管状构件（20）; 篮组件（12），包括：多个柔性花键（14）; 近端锚固件（18），用于牢固地固定花键（14）的近端部分（62）; 所述近端锚固件（18）固定在所述第一细长管状构件（20）的远端（20B）处; 用于牢固地固定花键（14）的远端部分（66）的远侧末端（16），所述近端锚固件（18）和所述远侧末端（16）在其间限定纵向轴线，所述纵向轴线在其之间布置花键（14） ; 其中所述花键（14）以大约90°或更小的角度（a）接近远侧末端（18）; 其中所述径向膨胀的非球形形状的所述花键（14）包含设置在所述花键（14）的远端部分（66）处的远端偏斜向外弯曲部（80），以使所述花键（14）向近侧锚 18）。

2. 发明申请

WO2011127211A3 METHODS, SYSTEM AND APPARATUS FOR THE DETECTION, DIAGNOSIS AND TREATMENT OF BIOLOGICAL RHYTHM DISORDERS 审中-公开
标题翻译：用于检测，诊断和治疗生物性红斑狼疮的方法，系统和装置
公开(公告)号：WO2011127211A3
公开(公告)日：2012-01-05
申请号：PCT/US2011031470
申请日：2011-04-06
申请人： UNIV CALIFORNIA , NARAYAN SANJIV M , SEHRA RUCHIR , TOPERA MEDICAL INC
发明人： NARAYAN SANJIV M , SEHRA RUCHIR
IPC分类号： A61B5/0472 , A61B5/042 , A61B5/046
CPC分类号： A61B5/0452 , A61B5/0255 , A61B5/04011 , A61B5/04012 , A61B5/0422 , A61B5/0432 , A61B5/044 , A61B5/0456 , A61B5/046 , A61B5/0464 , A61B5/0472 , A61B5/4857 , A61B5/6852 , A61B5/7221 , A61B5/726 , A61B5/7264 , A61B5/7278
摘要： System, assembly and method are provided to facilitate reconstruction of cardiac information representing a complex rhythm disorder associated with a patient's heart to indicate a source of the heart rhythm disorder. The complex rhythm disorder can be treated by application of energy to modify the source of the rhythm disorder.
摘要翻译：提供系统，组装和方法以便于重建表示与患者心脏相关联的复杂节律紊乱的心脏信息，以指示心律失常的来源。可以通过施加能量来改变节律紊乱的来源来治疗复杂的节律紊乱。

3. 发明申请

WO2012145077A1 METHOD FOR DETECTION OF CARDIAC RHYTHM DISORDERS USING BASKET STYLE CARDIAC MAPPING CATHETER 审中-公开
标题翻译：使用篮状花岗蛋白贴图导管检测心脏疾病的方法
公开(公告)号：WO2012145077A1
公开(公告)日：2012-10-26
申请号：PCT/US2012/027220
申请日：2012-03-01
申请人： TOPERA, INC. , KORDIS, Thomas, F. , SEHRA, Ruchir
发明人： KORDIS, Thomas, F. , SEHRA, Ruchir
IPC分类号： A61B5/042
CPC分类号： A61B5/0422 , A61B5/042 , A61B5/6858 , A61B5/6859 , A61B18/1492 , A61B2018/0016 , A61B2018/00267 , A61B2018/00351 , A61B2562/17 , F04C2270/0421 , Y10T29/49117
摘要： A method for sensing local electric voltages from endocardial surface of a heart, comprising: providing a system (10) for sensing multiple local electric voltages from endocardial surface of a heart, comprising: an elongate tubular member (20); a basket assembly (12) comprising: a plurality of flexible splines (14); wherein the splines (14) comprise a superelastic material such that the basket assembly (12) exhibits a radially expanded non-spherical shape when not radially compressed; and wherein each of the splines (14) in the radially expanded non-spherical shape contain a proximal recurve (76) in the proximate portion (62) of the spline (14), the proximal recurve (76) comprises a proximal excurvate outward bend (84) and a proximal incurvate inward bend (82); delivering the system (10) to the heart so that the basket assembly (12) is disposed within the right atrium of the heart; and contacting atrial tissue with the electrodes (186) disposed on the spline to detect local electric voltages from endocardial surface thereat.
摘要翻译：一种用于感测来自心脏心内膜表面的局部电压的方法，包括：提供用于感测来自心脏心内膜表面的多个局部电压的系统（10），包括：细长管状构件（20）; 篮组件（12），包括：多个柔性花键（14）; 其中所述花键（14）包括超弹性材料，使得所述筐组件（12）在未径向压缩时呈现出径向膨胀的非球形形状; 并且其中所述径向膨胀的非球形形状中的每个所述花键（14）在所述花键（14）的所述近似部分（62）中包含近端折曲（76），所述近端折曲（76）包括近端偏离向外弯曲（84）和近端固化的向内弯曲部（82）; 将系统（10）递送到心脏，使得篮组件（12）设置在心脏的右心房内; 并将心房组织与布置在花键上的电极（186）接触，以检测来自心内膜表面的局部电压。

4. 发明申请

WO2011127211A2 METHODS, SYSTEM AND APPARATUS FOR THE DETECTION, DIAGNOSIS AND TREATMENT OF BIOLOGICAL RHYTHM DISORDERS 审中-公开
标题翻译：用于检测，诊断和治疗生物性红斑狼疮的方法，系统和装置
公开(公告)号：WO2011127211A2
公开(公告)日：2011-10-13
申请号：PCT/US2011/031470
申请日：2011-04-06
申请人： THE REGENTS OF THE UNIVERSITY OF CALIFORNIA , NARAYAN, Sanjiv M. , SEHRA, Ruchir , TOPERA MEDICAL, INC.
发明人： NARAYAN, Sanjiv M. , SEHRA, Ruchir
IPC分类号： A61B5/042
CPC分类号： A61B5/0452 , A61B5/0255 , A61B5/04011 , A61B5/04012 , A61B5/0422 , A61B5/0432 , A61B5/044 , A61B5/0456 , A61B5/046 , A61B5/0464 , A61B5/0472 , A61B5/4857 , A61B5/6852 , A61B5/7221 , A61B5/726 , A61B5/7264 , A61B5/7278
摘要： System, assembly and method are provided to facilitate reconstruction of cardiac information representing a complex rhythm disorder associated with a patient's heart to indicate a source of the heart rhythm disorder. The complex rhythm disorder can be treated by application of energy to modify the source of the rhythm disorder.
摘要翻译：提供系统，组装和方法以便于重建表示与患者心脏相关联的复杂节律紊乱的心脏信息，以指示心律失常的来源。可以通过施加能量来改变节律紊乱的来源来治疗复杂的节律紊乱。

5. 发明申请

WO2011127209A1 METHODS, SYSTEM AND APPARATUS FOR THE DETECTION, DIAGNOSIS AND TREATMENT OF BIOLOGICAL RHYTHM DISORDERS 审中-公开
标题翻译：用于检测，诊断和治疗生物节律异常的方法，系统和装置
公开(公告)号：WO2011127209A1
公开(公告)日：2011-10-13
申请号：PCT/US2011/031468
申请日：2011-04-06
申请人： THE REGENTS OF THE UNIVERSITY OF CALIFORNIA , NARAYAN, Sanjiv M. , SEHRA, Ruchir , TOPERA MEDICAL, INC.
发明人： NARAYAN, Sanjiv M. , SEHRA, Ruchir
IPC分类号： A61B5/0472 , A61B5/042 , A61B5/046
CPC分类号： A61B5/0452 , A61B5/0255 , A61B5/04011 , A61B5/04012 , A61B5/0422 , A61B5/0432 , A61B5/044 , A61B5/0456 , A61B5/046 , A61B5/0464 , A61B5/0472 , A61B5/4857 , A61B5/6852 , A61B5/7221 , A61B5/726 , A61B5/7264 , A61B5/7278
摘要： System, assembly and method are provided to facilitate reconstruction of cardiac information representing a complex rhythm disorder associated with a patient's heart to indicate a source of the heart rhythm disorder. The complex rhythm disorder can be treated by application of energy to modify the source of the rhythm disorder.
摘要翻译：提供系统，组件和方法以促进表示与患者心脏相关联的复杂节律紊乱的心脏信息的重建，以指示心律紊乱的来源。复杂的节奏障碍可以通过应用能量来改变节奏障碍的来源。

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