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1. 发明申请

WO2010148256A1 FUEL COMPOSITIONS COMPRISING ISOPRENE DERIVATIVES 审中-公开
标题翻译：包含异丙苯衍生物的燃料组合物
公开(公告)号：WO2010148256A1
公开(公告)日：2010-12-23
申请号：PCT/US2010/039088
申请日：2010-06-17
申请人： DANISCO US INC. , MCAULIFFE, Joseph, C. , PARAMONOV, Sergey, E. , SANFORD, Karl, J.
发明人： MCAULIFFE, Joseph, C. , PARAMONOV, Sergey, E. , SANFORD, Karl, J.
IPC分类号： C07C5/02
CPC分类号： C10L1/04 , C07C9/14
摘要： The invention provides for methods, compositions and systems using bioisoprene derived from renewable carbon for production of a variety of hydrocarbon fuels and fuel additives.
摘要翻译：本发明提供了使用衍生自可再生碳的生物异戊二烯用于生产各种烃燃料和燃料添加剂的方法，组合物和系统。

2. 发明申请

WO2011075748A1 MEMBRANE BIOREACTOR FOR INCREASED PRODUCTION OF ISOPRENE GAS 审中-公开
标题翻译：用于增加异丙苯生产的膜生物反应器
公开(公告)号：WO2011075748A1
公开(公告)日：2011-06-23
申请号：PCT/US2010/061913
申请日：2010-12-22
申请人： DANISCO US INC. , THE GOODYEAR TIRE & RUBBER COMPANY , CALABRIA, Anthony R. , CHOTANI, Gopal K. , FONG, Robin , NIELSEN, Alex T. , SANFORD, Karl J.
发明人： CALABRIA, Anthony R. , CHOTANI, Gopal K. , FONG, Robin , NIELSEN, Alex T. , SANFORD, Karl J.
IPC分类号： C12P5/02
CPC分类号： C12P5/007 , Y02E50/343
摘要： The invention provides improved methods for the production of isoprene from biological materials.
摘要翻译：本发明提供从生物材料生产异戊二烯的改进方法。

3. 发明申请

WO2010031068A1 REDUCTION OF CARBON DIOXIDE EMISSION DURING ISOPRENE PRODUCTION BY FERMENTATION 审中-公开
标题翻译：通过发酵减少异丙酚生产过程中的二氧化碳排放
公开(公告)号：WO2010031068A1
公开(公告)日：2010-03-18
申请号：PCT/US2009/057021
申请日：2009-09-15
申请人： DANISCO US INC. , THE GOODYEAR TIRE & RUBBER COMPANY , CHOTANI, Gopal, K. , NIELSEN, Alex , SANFORD, Karl, J.
发明人： CHOTANI, Gopal, K. , NIELSEN, Alex , SANFORD, Karl, J.
IPC分类号： C12N1/20 , C12P5/02
CPC分类号： C12P5/007 , C12N1/20 , Y02E50/343
摘要： The present invention provides methods for increasing the amount of isoprene produced by cultured cells with only a minimal increase in carbon dioxide emitted, thereby resulting in process having a greater yield of isoprene relative to carbon dioxide. In addition, the present invention provides compositions that include the cultured cells or isoprene produced there from.
摘要翻译：本发明提供了增加培养细胞产生的异戊二烯量的方法，其中发射的二氧化碳的增加只有极小的增加，从而导致异戊二烯相对于二氧化碳的产量更高的方法。此外，本发明提供了包含从其制备的培养细胞或异戊二烯的组合物。

4. 发明申请

WO2009076676A3 COMPOSITIONS AND METHODS FOR PRODUCING ISOPRENE 审中-公开
公开(公告)号：WO2009076676A3
公开(公告)日：2009-06-18
申请号：PCT/US2008/086869
申请日：2008-12-15
申请人： DANISCO US INC. , THE GOODYEAR TIRE & RUBBER COMPANY , CERVIN, Marguerite , WHITED, Gregory, M. , CHOTANI, Gopal, K. , VALLE, Fernando , FIORESI, Carol , SANFORD, Karl, J. , MCAULIFFE, Joseph, C. , FEHER, Frank, J. , PUHALA, Aaron, S. , MIASNIKOV, Andrei , ALDOR, Ilana, S.
发明人： CERVIN, Marguerite , WHITED, Gregory, M. , CHOTANI, Gopal, K. , VALLE, Fernando , FIORESI, Carol , SANFORD, Karl, J. , MCAULIFFE, Joseph, C. , FEHER, Frank, J. , PUHALA, Aaron, S. , MIASNIKOV, Andrei , ALDOR, Ilana, S.
IPC分类号： C12P5/02
摘要： The invention features methods for producing isoprene from cultured cells. The invention also provides compositions that include these cultured cells.

5. 发明申请

WO2010078457A2 METHODS OF PRODUCING ISOPRENE AND A CO-PRODUCT 审中-公开
标题翻译：生产异戊二烯和副产物的方法
公开(公告)号：WO2010078457A2
公开(公告)日：2010-07-08
申请号：PCT/US2009/069862
申请日：2009-12-30
申请人： DANISCO US INC. , THE GOODYEAR TIRE & RUBBER COMPANY , CHOTANI, Gopal, K. , MCAULIFFE, Joseph, C. , PERES, Caroline, M. , WELLS, Derek, H. , SANFORD, Karl, J.
发明人： CHOTANI, Gopal, K. , MCAULIFFE, Joseph, C. , PERES, Caroline, M. , WELLS, Derek, H. , SANFORD, Karl, J.
IPC分类号： C12N9/88 , C12N5/10
CPC分类号： C12P5/007 , C12N9/88 , C12P7/06 , C12P7/065 , C12P7/18 , Y02E50/17
摘要： The invention features methods producing isoprene and a co-product, such as ethanol, 1,3- propanediol, or hydrogen from cultured cells. The invention also provides compositions that include these cultured cells. The invention provides compositions comprising isoprene and ethanol, isoprene and 1,3-propanediol, and isoprene and hydrogen. Additionally, the invention provides methods of co-producing isoprene and ethanol, isoprene and 1,3-propanediol, and isoprene and hydrogen by culturing cells under conditions suitable for co-production of isoprene and ethanol, isoprene and 1,3-propanediol, and isoprene and hydrogen.
摘要翻译：本发明的特征在于生产异戊二烯和共产物例如乙醇，1,3-丙二醇或来自培养细胞的氢的方法。本发明还提供了包含这些培养细胞的组合物。本发明提供了包含异戊二烯和乙醇，异戊二烯和1,3-丙二醇以及异戊二烯和氢的组合物。此外，本发明提供了通过在适于异戊二烯和乙醇，异戊二烯和1,3-丙二醇的共生产的条件下培养细胞来共同生产异戊二烯和乙醇，异戊二烯和1,3-丙二醇以及异戊二烯和氢的方法，以及异戊二烯和氢气。

6. 发明申请

WO2010005525A1 POLYMERS OF ISOPRENE FROM RENEWABLE RESOURCES 审中-公开
标题翻译：可再生能源的ISOPRENE聚合物
公开(公告)号：WO2010005525A1
公开(公告)日：2010-01-14
申请号：PCT/US2009/003897
申请日：2009-06-30
申请人： THE GOODYEAR TIRE & RUBBER COMPANY , GENENCOR INTERNATIONAL, INC. , FEHER, Frank, J. , WHITED, Gregory, M. , CHOTANI, Gopal, K. , VALLE, Fernando , FIORESI, Carol , SANFORD, Karl, J. , MCAULIFFE, Joseph, C. , CERVIN, Marguerite , PUHALA, Aaron, S. , MIASNIKOV, Andrei , ALDOR, Illana, S.
发明人： FEHER, Frank, J. , WHITED, Gregory, M. , CHOTANI, Gopal, K. , VALLE, Fernando , FIORESI, Carol , SANFORD, Karl, J. , MCAULIFFE, Joseph, C. , CERVIN, Marguerite , PUHALA, Aaron, S. , MIASNIKOV, Andrei , ALDOR, Illana, S.
IPC分类号： C12P5/02 , C07C1/00
CPC分类号： C08F236/18 , C08F2/00 , C08F36/04 , C08F136/08 , C08F236/08 , C08F236/10 , C08F236/12 , C08L9/00 , C12P5/007 , Y10T436/24
摘要： It has been found that certain cells in culture can convert carbon available in the cell culture medium into isoprene These cells have a heterologous nucleic acid which is operably linked to a promoter and encodes an isoprene synthase polypeptide The isoprene produced in such a cultured medium can then be recovered and polymenzed into synthetic rubbers and other useful polymeπc matenals The synthetic isoprene containing polymers of this invention offer the benefit of being verifiable as to being denved from non- petrochemical based resources They can also be analytically distinguished from rubbers that come from natural sources The present invention more specifically discloses a polyisoprene polymer which is comprised of repeat units that are denved from isoprene monomer, wherein the polyisoprene polymer has delta 13C value of greater than -22%o This type of polyisoprene can be a αs-1 A- polyisoprene homopolymer rubber.
摘要翻译：已经发现，培养物中的某些细胞可将细胞培养基中可获得的碳转化为异戊二烯。这些细胞具有与启动子可操作地连接并编码异戊二烯合酶多肽的异源核酸。然后可以在这样的培养基中产生的异戊二烯被回收和聚合成合成橡胶和其他有用的聚合物材料本发明的合成异戊二烯聚合物提供了可被验证为从非石化基础资源中被证实的益处。它们还可以与来自天然来源的橡胶进行分析区分。本发明更具体地公开了由异戊二烯单体所取代的重复单元组成的聚异戊二烯聚合物，其中聚异戊二烯聚合物具有大于-22％的δ13 C值。这种类型的聚异戊二烯可以是一种1-聚异戊二烯均聚物橡胶。

7. 发明申请

WO2003066816A3 METHODS FOR PRODUCING END-PRODUCTS FROM CARBON SUBSTRATES 审中-公开
公开(公告)号：WO2003066816A3
公开(公告)日：2003-08-14
申请号：PCT/US2003/003532
申请日：2003-02-06
申请人： GENENCOR INTERNATIONAL, INC. , CHOTANI, Gopal, K. , KUMAR, Manoj , PUCCI, Jeff, P. , SANFORD, Karl, J. , SHETTY, Jayarama, K.
发明人： CHOTANI, Gopal, K. , KUMAR, Manoj , PUCCI, Jeff, P. , SANFORD, Karl, J. , SHETTY, Jayarama, K.
IPC分类号： C12P19/24
摘要： The present invention provides means for the production of desired end-products of in vitro and/or in vivo bioconversion of biomass-based feed stock substrates, including but not limited to such materials as starch and cellulose. In particularly preferred embodiments, the methods of the present invention do not require gelatinization and/or liquefaction of the substrate.

8. 发明申请

WO03066816A2 METHODS FOR PRODUCING END-PRODUCTS FROM CARBON SUBSTRATES 审中-公开
标题翻译：从碳底物生产终产物的方法
公开(公告)号：WO03066816A2
公开(公告)日：2003-08-14
申请号：PCT/US0303532
申请日：2003-02-06
申请人： GENENCOR INT , CHOTANI GOPAL K , KUMAR MANOJ , PUCCI JEFF P , SANFORD KARL J , SHETTY JAYARAMA K
发明人： CHOTANI GOPAL K , KUMAR MANOJ , PUCCI JEFF P , SANFORD KARL J , SHETTY JAYARAMA K
IPC分类号： C12P7/06 , C12P7/10 , C12P7/18 , C12P7/20 , C12P7/44 , C12P7/56 , C12P7/58 , C12P7/60 , C12P19/02 , C12N
CPC分类号： C12P19/02 , C12P7/06 , C12P7/10 , C12P7/18 , C12P7/20 , C12P7/44 , C12P7/56 , C12P7/58 , C12P7/60 , Y02E50/16 , Y02E50/17
摘要： The present invention provides means for the production of desired end-products of in vitro and/or in vivo bioconversion of biomass-based feed stock substrates, including but not limited to such materials as starch and cellulose. In particularly preferred embodiments, the methods of the present invention do not require gelatinization and/or liquefaction of the substrate.
摘要翻译：本发明提供了生产基于生物质的原料基质的体外和/或体内生物转化所需的终产物的方法，包括但不限于淀粉和纤维素等材料。在特别优选的实施方案中，本发明的方法不需要基质的凝胶化和/或液化。

9. 发明申请

WO2010148144A1 POLYMERIZATION OF ISOPRENE FROM RENEWABLE RESOURCES 审中-公开
标题翻译：可再生能源的异丙苯聚合
公开(公告)号：WO2010148144A1
公开(公告)日：2010-12-23
申请号：PCT/US2010/038898
申请日：2010-06-16
申请人： DANISCO US INC. , THE GOODYEAR TIRE & RUBBER COMPANY , MCAULIFFE, Joseph, C. , PARAMONOV, Sergey , RODEWALD, Stephan , SANFORD, Karl, J.
发明人： MCAULIFFE, Joseph, C. , PARAMONOV, Sergey , RODEWALD, Stephan , SANFORD, Karl, J.
IPC分类号： C08F293/00 , C08F295/00
CPC分类号： C08F4/52 , C08F4/16 , C08F36/08 , C12P5/007 , Y02E50/343
摘要： The invention features compositions and methods for producing polymers of isoprene derived from renewable resources such as isoprene produced from cultured cells that use renewable carbon sources. A starting isoprene composition, such as a bioisoprene composition, is distinguished from petroleum based isoprene by the purity profile (such as lower levels of certain C5 hydrocarbons other than isoprene, presence of certain compounds associated with the biological process for production) and the relative content of the carbon isotopes. Polymers obtained by polymerization of such starting isoprene composition according to this invention, such as a polyisoprene homopolymer or a copolymer having repeat units that are derived from isoprene, are distinguishable from isoprene containing polymers from petrochemical resources. The present invention more specifically discloses a polyisoprene polymer which is comprised of repeat units that are derived from isoprene monomer, wherein the polyisoprene polymer has d 13 C value of greater than -22‰. This type of polyisoprene can be a cis-1,4-polyisoprene homopolymer rubber. Also provided are methods for verifying that a polyisoprene homopolymer or a copolymer having repeat units that are derived from isoprene contains isoprene that is from a sustainable renewable non- petroleum derived source.
摘要翻译：本发明的特征是用于生产衍生自可再生资源的异戊二烯聚合物的组合物和方法，例如由使用可再生碳源的培养细胞产生的异戊二烯。起始的异戊二烯组合物如生物异戊二烯组合物通过纯度分布（例如除异戊二烯以外的某些C5烃的较低水平，与生产生物过程相关的某些化合物的存在）以及相对含量的碳同位素。通过聚合本发明的这种起始异戊二烯组合物得到的聚合物，例如聚异戊二烯均聚物或具有衍生自异戊二烯的重复单元的共聚物，与来自石油化学资源的含异戊二烯聚合物是不同的。本发明更具体地公开了由衍生自异戊二烯单体的重复单元组成的聚异戊二烯聚合物，其中聚异戊二烯聚合物的d13C值大于-220 / 00。这种类型的聚异戊二烯可以是顺式-1,4-聚异戊二烯均聚物橡胶。还提供了用于验证聚异戊二烯均聚物或具有衍生自异戊二烯的重复单元的共聚物含有来自可持续可再生非石油衍生源的异戊二烯的方法。

10. 发明申请

WO2010031076A3 CONVERSION OF PRENYL DERIVATIVES TO ISOPRENE 审中-公开
标题翻译：将衍生物转化为异丙肾上腺素
公开(公告)号：WO2010031076A3
公开(公告)日：2010-11-11
申请号：PCT/US2009057036
申请日：2009-09-15
申请人： DANISCO US INC , GOODYEAR TIRE & RUBBER , MCAULIFFE JOSEPH C , RATHNAYAKE SAMIRA , SANFORD KARL J
发明人： MCAULIFFE JOSEPH C , RATHNAYAKE SAMIRA , SANFORD KARL J
IPC分类号： C12P5/02
CPC分类号： C12P5/007 , C07C1/2078 , C07C1/24 , C12N9/14 , C12N9/16 , C12N9/88 , C12N9/90 , C12Y301/03 , C12Y301/07 , C12Y306/01 , C12Y503/03002
摘要： The present invention provides methods for producing derivatives from cultured cells. In addition, the present invention provides methods for conversion of prenyl derivatives, obtained from biological or petrochemical sources, to isoprene by employing chemical or biological catalysts. The present invention also provides compositions that include the cultured cells or isoprene or prenyl derivatives produced there from.
摘要翻译：本发明提供了从培养细胞产生衍生物的方法。此外，本发明提供了通过使用化学或生物催化剂将由生物或石油化学源获得的异戊烯基衍生物转化为异戊二烯的方法。本发明还提供了包含从其制备的培养细胞或异戊二烯或异戊二烯基衍生物的组合物。

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