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    • 3. 发明授权
    • Method of treating blepharitis
    • 治疗睑炎的方法
    • US08349806B2
    • 2013-01-08
    • US12501316
    • 2009-07-10
    • Kurt E. BrubakerRomulus K. BrazzellReza M. HaqueJohn C. Ice, Jr.José L. BoyerJoseph B. BoydRobert J. Dempsey
    • Kurt E. BrubakerRomulus K. BrazzellReza M. HaqueJohn C. Ice, Jr.José L. BoyerJoseph B. BoydRobert J. Dempsey
    • A61K31/7052
    • A61K31/7052A61K9/0048
    • The present invention relates to a method for treating non-infectious, inflammatory chronic posterior blepharitis in a subject. The present invention also relates to a method for treating chronic posterior blepharitis in a subject for over two weeks. The method comprises identifying a subject in need thereof, and topically administering to the eye of the subject a pharmaceutical formulation consisting essentially of an effective amount azithromycin. The present invention further relates to a method for treating dry eye secondary to blepharitis in a subject. The method comprises the steps of: identifying a subject suffering from dry eye secondary to posterior blepharitis, and topically administering to the eye of the subject a pharmaceutical formulation comprising an effective amount of azithromycin. The present invention further relates to method for reducing contact lens intolerance of a subject due to blepharitis or dry eye secondary to blepharitis.
    • 本发明涉及治疗受试者中非传染性,炎性慢性后睑炎的方法。 本发明还涉及治疗受试者的慢性后睑炎的方法超过两周。 该方法包括鉴定有需要的受试者,并且对受试者的眼睛局部施用基本上由有效量的阿奇霉素组成的药物制剂。 本发明还涉及一种治疗受试者的睑缘炎继发性干眼症的方法。 该方法包括以下步骤:鉴定患有后睑炎继发性干眼症的受试者,并且向受试者的眼睛局部施用包含有效量的阿奇霉素的药物制剂。 本发明还涉及减少由于睑炎引起的睑缘炎或干眼引起的受试者的隐形眼镜不耐受的方法。